Design, synthesis and anticancer activities of hybrids of indole and barbituric acids-Identification of highly promising leads

Bioorganic and Medicinal Chemistry Letters

Volumn 19, Issue 11, 2009, Pages 3054-3058

  Singh, Palwinder ^a   Kaur, Matinder ^a   Verma, Pooja ^a  

^a GURU NANAK DEV UNIVERSITY   (India)

Author keywords

Anticancer activities; Barbituric acid; Hybrid molecules; Indole

Indexed keywords

BARBITURIC ACID DERIVATIVE; CYCLOOXYGENASE 2; FLUOROURACIL; INDOLE DERIVATIVE; INDOMETACIN; RIBONUCLEOTIDE REDUCTASE; THYMIDYLATE SYNTHASE;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL CULTURE; CONTROLLED STUDY; DRUG DESIGN; DRUG IDENTIFICATION; DRUG STRUCTURE; DRUG SYNTHESIS; HUMAN; HUMAN CELL; PROTEIN INTERACTION;

ANTINEOPLASTIC AGENTS; BARBITURATES; CATALYTIC DOMAIN; CELL LINE, TUMOR; COMPUTER SIMULATION; CYCLOOXYGENASE 2; DRUG DESIGN; DRUG SCREENING ASSAYS, ANTITUMOR; HUMANS; INDOLES; PYRIMIDINONES; RIBONUCLEOTIDE REDUCTASES; STRUCTURE-ACTIVITY RELATIONSHIP; THYMIDYLATE SYNTHASE;

EID: 65149100170     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2009.04.014     Document Type: Article

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