Novel antileishmanial chalconoids: Synthesis and biological activity of 1- or 3-(6-chloro-2H-chromen-3-yl)propen-1-ones

European Journal of Medicinal Chemistry

Volumn 45, Issue 4, 2010, Pages 1424-1429

  Nazarian, Zohreh ^a   Emami, Saeed ^b   Heydari, Samaneh ^c   Ardestani, Sussan K ^d   Nakhjiri, Maryam ^a   Poorrajab, Fatemeh ^d   Shafiee, Abbas ^a   Foroumadi, Alireza ^a,c  

^a TEHRAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^b MAZANDARAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^c TEHRAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^d UNIVERSITY OF TEHRAN   (Iran)

Author keywords

Antileishmanial activity; Chalcones; Chromene; Leishmania major

Indexed keywords

1 (6 CHLORO 2H CHROMEN 3 YL) 3 (2,3 DIMETHOXYPHENYL)PROP 2 EN 1 ONE; 1 (6 CHLORO 2H CHROMEN 3 YL) 3 (2,5 DIMETHOXYPHENYL)PROP 2 EN 1 ONE; 1 (6 CHLORO 2H CHROMEN 3 YL) 3 (4 METHYLPHENYL)PROP 2 EN 1 ONE; 1 (6 CHLORO 2H CHROMEN 3 YL)PROPEN 1 ONE; 3 (2 BROMOPHENYL) 1 (6 CHLORO 2H CHROMEN 3 YL)PROP 2 EN 1 ONE; 3 (6 CHLORO 2H CHROMEN 3 YL) 1 (2 CHLOROPHENYL)PROP 2 EN 1 ONE; 3 (6 CHLORO 2H CHROMEN 3 YL) 1 (2 FLUOROPHENYL)PROPEN 2 EN 1 ONE; 3 (6 CHLORO 2H CHROMEN 3 YL) 1 (2,4 DICHLOROPHENYL)PROP 2 EN 1 ONE; 3 (6 CHLORO 2H CHROMEN 3 YL) 1 (3,4,5 TRIMETHOXYPHENYL)PROP 2 EN 1 ONE; 3 (6 CHLORO 2H CHROMEN 3 YL)PROPEN 1 ONE; ANTILEISHMANIAL AGENT; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DRUG ACTIVITY; DRUG CYTOTOXICITY; DRUG SCREENING; DRUG STRUCTURE; DRUG SYNTHESIS; IC 50; LEISHMANIA MAJOR; MOUSE; NONHUMAN; PERITONEUM MACROPHAGE; PHYSICAL CHEMISTRY; PROMASTIGOTE;

ANIMALS; ANTIPROTOZOAL AGENTS; CELLS, CULTURED; CHALCONES; LEISHMANIA MAJOR; MACROPHAGES, PERITONEAL; MAGNETIC RESONANCE SPECTROSCOPY; MASS SPECTROMETRY; MICE; SPECTROPHOTOMETRY, INFRARED;

EID: 77349089250     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2009.12.046     Document Type: Article

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