-
1
-
-
77954033982
-
3d pib and csf biomarker associations with hippocampal atrophy in adni subjects
-
Apostolova LG, Hwang KS, Andrawis JP, et al. 3D PIB and CSF biomarker associations with hippocampal atrophy in ADNI subjects. Neurobiol Aging 2010;31:1284-303
-
(2010)
Neurobiol Aging
, vol.31
, pp. 1284-303
-
-
Apostolova, L.G.1
Hwang, K.S.2
Andrawis, J.P.3
-
2
-
-
34047202247
-
Hippocampal and entorhinal atrophy in mild cognitive impairment: Prediction of alzheimer disease
-
Devanand DP, Pradhaban G, Liu X, et al. Hippocampal and entorhinal atrophy in mild cognitive impairment: Prediction of Alzheimer disease. Neurology 2007;68:828-36
-
(2007)
Neurology
, vol.68
, pp. 828-36
-
-
Devanand, D.P.1
Pradhaban, G.2
Liu, X.3
-
3
-
-
0347091262
-
Cholinergic plasticity in hippocampus of individuals with mild cognitive impairment: Correlation with alzheimer's neuropathology
-
Ikonomovic MD, Mufson EJ, Wuu J, Cochran EJ, Bennett DA, DeKosky ST. Cholinergic plasticity in hippocampus of individuals with mild cognitive impairment: Correlation with Alzheimer's neuropathology. J Alzheimers Dis 2003;5:39-48
-
(2003)
J Alzheimers Dis
, vol.5
, pp. 39-48
-
-
Ikonomovic, M.D.1
Mufson, E.J.2
Wuu, J.3
Cochran, E.J.4
Bennett, D.A.5
DeKosky, S.T.6
-
4
-
-
0036156958
-
Upregulation of choline acetyltransferase activity in hippocampus and frontal cortex of elderly subjects with mild cognitive impairment
-
DeKosky ST, Ikonomovic MD, Styren SD, et al. Upregulation of choline acetyltransferase activity in hippocampus and frontal cortex of elderly subjects with mild cognitive impairment. Ann Neurol 2002;51:145-55
-
(2002)
Ann Neurol
, vol.51
, pp. 145-55
-
-
DeKosky, S.T.1
Ikonomovic, M.D.2
Styren, S.D.3
-
5
-
-
0036810329
-
Alzheimer's disease and the basal forebrain cholinergic system: Relations to beta-amyloid peptides, cognition, and treatment strategies
-
Auld DS, Kornecook TJ, Bastianetto S, Quirion R. Alzheimer's disease and the basal forebrain cholinergic system: Relations to beta-amyloid peptides, cognition, and treatment strategies. Prog Neurobiol 2002;68: 209-45
-
(2002)
Prog Neurobiol
, vol.68
, pp. 209-45
-
-
Auld, D.S.1
Kornecook, T.J.2
Bastianetto, S.3
Quirion, R.4
-
7
-
-
84857034775
-
Mild cognitive impairment: Pathology and mechanisms
-
Mufson EJ, Binder L, Counts SE, et al. Mild cognitive impairment: Pathology and mechanisms. Acta Neuropathol 2012;123:13-30
-
(2012)
Acta Neuropathol
, vol.123
, pp. 13-30
-
-
Mufson, E.J.1
Binder, L.2
Counts, S.E.3
-
8
-
-
2042465006
-
The nerve growth factor precursor prongf exhibits neurotrophic activity but is less active than mature nerve growth factor
-
Fahnestock M, Yu G, Michalski B, et al. The nerve growth factor precursor proNGF exhibits neurotrophic activity but is less active than mature nerve growth factor. J Neurochem 2004;89:581-92
-
(2004)
J Neurochem
, vol.89
, pp. 581-92
-
-
Fahnestock, M.1
Yu, G.2
Michalski, B.3
-
9
-
-
1542349149
-
Neurobiology: A move to sort life from death
-
Kaplan DR, Miller FD. Neurobiology: A move to sort life from death. Nature 2004;427:798-99
-
(2004)
Nature
, vol.427
, pp. 798-99
-
-
Kaplan, D.R.1
Miller, F.D.2
-
10
-
-
10744219632
-
Sortilin is essential for prongf-induced neuronal cell death
-
Nykjaer A, Lee R, Teng KK, et al. Sortilin is essential for proNGF-induced neuronal cell death. Nature 2004;427:843-48
-
(2004)
Nature
, vol.427
, pp. 843-48
-
-
Nykjaer, A.1
Lee, R.2
Teng, K.K.3
-
11
-
-
0037093730
-
Dual role for p75(ntr) signaling in survival and cell death: Can intracellular mediators provide an explanation?
-
Mamidipudi V, Wooten MW. Dual role for p75(NTR) signaling in survival and cell death: Can intracellular mediators provide an explanation? J Neurosci Res 2002;68:373-84
-
(2002)
J Neurosci Res
, vol.68
, pp. 373-84
-
-
Mamidipudi, V.1
Wooten, M.W.2
-
12
-
-
1642540257
-
Neurotrophins and their receptors: Signaling trios in complex biological systems
-
Teng KK, Hempstead BL. Neurotrophins and their receptors: Signaling trios in complex biological systems. Cell Mol Life Sci 2004;61:35-48
-
(2004)
Cell Mol Life Sci
, vol.61
, pp. 35-48
-
-
Teng, K.K.1
Hempstead, B.L.2
-
13
-
-
20044370999
-
Probdnf induces neuronal apoptosis via activation of a receptor complex of p75ntr and sortilin
-
Teng HK, Teng KK, Lee R, et al. ProBDNF induces neuronal apoptosis via activation of a receptor complex of p75NTR and sortilin. J Neurosci 2005;25:5455-63
-
(2005)
J Neurosci
, vol.25
, pp. 5455-63
-
-
Teng, H.K.1
Teng, K.K.2
Lee, R.3
-
14
-
-
0000326996
-
Competitive signaling between trka and p75 nerve growth factor receptors determines cell survival
-
Yoon SO, Casaccia-Bonnefil P, Carter B, Chao MV.Competitive signaling between TrkA and p75 nerve growth factor receptors determines cell survival. J Neurosci 1998;18:3273-81
-
(1998)
J Neurosci
, vol.18
, pp. 3273-81
-
-
Yoon, S.O.1
Casaccia-Bonnefil, P.2
Carter, B.3
Chao, M.V.4
-
15
-
-
54349117308
-
Human prongf: Biological effects and binding profiles at trka, p75ntr, and sortilin
-
Clewes O, Fahey MS, Tyler SJ, et al. Human ProNGF: Biological effects and binding profiles at TrkA, P75NTR, and sortilin. J Neurochem 2008; 107:1124-35
-
(2008)
J Neurochem
, vol.107
, pp. 1124-35
-
-
Clewes, O.1
Fahey, M.S.2
Tyler, S.J.3
-
17
-
-
78449258688
-
Prongf induces pten via p75ntr to suppress trk-mediated survival signaling in brain neurons
-
Song W, Volosin M, Cragnolini AB, Hempstead BL, Friedman WJ. ProNGF induces PTEN via p75NTR to suppress Trk-mediated survival signaling in brain neurons. J Neurosci 2010;30:15608-15
-
(2010)
J Neurosci
, vol.30
, pp. 15608-15
-
-
Song, W.1
Volosin, M.2
Cragnolini, A.B.3
Hempstead, B.L.4
Friedman, W.J.5
-
18
-
-
78650678063
-
Sortilin associates with trk receptors to enhance anterograde transport and neurotrophin signaling
-
Vaegter CB, Jansen P, Fjorback AW, et al. Sortilin associates with Trk receptors to enhance anterograde transport and neurotrophin signaling. Nat Neurosci 2011;14:54-61
-
(2011)
Nat Neurosci
, vol.14
, pp. 54-61
-
-
Vaegter, C.B.1
Jansen, P.2
Fjorback, A.W.3
-
19
-
-
0034044227
-
Neurotrophin signal transduction in the nervous system
-
Kaplan DR, Miller FD. Neurotrophin signal transduction in the nervous system. Curr Opin Neurobiol 2000;10:381-91
-
(2000)
Curr Opin Neurobiol
, vol.10
, pp. 381-91
-
-
Kaplan, D.R.1
Miller, F.D.2
-
20
-
-
0033215974
-
Ceramide signaling downstream of the p75 neurotrophin receptor mediates the effects of nerve growth factor on outgrowth of cultured hippocampal neurons
-
Brann AB, Scott R, Neuberger Y, et al. Ceramide signaling downstream of the p75 neurotrophin receptor mediates the effects of nerve growth factor on outgrowth of cultured hippocampal neurons. J Neurosci 1999; 19:8199-206
-
(1999)
J Neurosci
, vol.19
, pp. 8199-206
-
-
Brann, A.B.1
Scott, R.2
Neuberger, Y.3
-
21
-
-
26844507790
-
A trka-to-p75ntr molecular switch activates amyloid beta-peptide generation during aging
-
Costantini C, Weindruch R, Della Valle G, Puglielli L. A TrkA-to-p75NTR molecular switch activates amyloid beta-peptide generation during aging. Biochem J 2005;391:59-67
-
(2005)
Biochem J
, vol.391
, pp. 59-67
-
-
Costantini, C.1
Weindruch, R.2
Della Valle, G.3
Puglielli, L.4
-
22
-
-
16244391770
-
Activation of akt/pkb, increased phosphorylation of akt substrates and loss and altered distribution of akt and pten are features of alzheimer's disease pathology
-
Griffin RJ, Moloney A, Kelliher M, et al. Activation of Akt/PKB, increased phosphorylation of Akt substrates and loss and altered distribution of Akt and PTEN are features of Alzheimer's disease pathology. J Neurochem 2005;93:105-17
-
(2005)
J Neurochem
, vol.93
, pp. 105-17
-
-
Griffin, R.J.1
Moloney, A.2
Kelliher, M.3
-
23
-
-
0036140118
-
Activation of rac gtpase by p75 is necessary for c-jun n-terminal kinaseymediated apoptosis
-
Harrington AW, Kim JY, Yoon SO. Activation of Rac GTPase by p75 is necessary for c-jun N-terminal kinaseYmediated apoptosis. J Neurosci 2002;22:156-66
-
(2002)
J Neurosci
, vol.22
, pp. 156-66
-
-
Harrington, A.W.1
Kim, J.Y.2
Yoon, S.O.3
-
24
-
-
0032864612
-
Entorhinal cortex beta-amyloid load in individuals with mild cognitive impairment
-
Mufson EJ, Chen EY, Cochran EJ, Beckett LA, Bennett DA, Kordower JH. Entorhinal cortex beta-amyloid load in individuals with mild cognitive impairment. Exp Neurol 1999;158:469-90
-
(1999)
Exp Neurol
, vol.158
, pp. 469-90
-
-
Mufson, E.J.1
Chen, E.Y.2
Cochran, E.J.3
Beckett, L.A.4
Bennett, D.A.5
Kordower, J.H.6
-
25
-
-
33745876233
-
Neuropathology of older persons without cognitive impairment from two community-based studies
-
Bennett DA, Schneider JA, Arvanitakis Z, et al. Neuropathology of older persons without cognitive impairment from two community-based studies. Neurology 2006;66:1837-44
-
(2006)
Neurology
, vol.66
, pp. 1837-44
-
-
Bennett, D.A.1
Schneider, J.A.2
Arvanitakis, Z.3
-
26
-
-
14644416500
-
Mild cognitive impairment is related to alzheimer disease pathology and cerebral infarctions
-
Bennett DA, Schneider JA, Bienias JL, Evans DA, Wilson RS. Mild cognitive impairment is related to Alzheimer disease pathology and cerebral infarctions. Neurology 2005;64:834-41
-
(2005)
Neurology
, vol.64
, pp. 834-41
-
-
Bennett, D.A.1
Schneider, J.A.2
Bienias, J.L.3
Evans, D.A.4
Wilson, R.S.5
-
27
-
-
84855988108
-
Rac1b increases with progressive tau pathology within cholinergic nucleus basalis neurons in alzheimer's disease
-
Perez SE, Getova DP, He B, et al. Rac1b increases with progressive tau pathology within cholinergic nucleus basalis neurons in Alzheimer's disease. Am J Pathol 2012;180:526-40
-
(2012)
Am J Pathol
, vol.180
, pp. 526-40
-
-
Perez, S.E.1
Getova, D.P.2
He, B.3
-
28
-
-
0033845932
-
Preclinical ad revisited: Neuropathology of cognitively normal older adults
-
Schmitt FA, Davis DG, Wekstein DR, et al. ''Preclinical'' AD revisited: Neuropathology of cognitively normal older adults. Neurology 2000;55: 370-76
-
(2000)
Neurology
, vol.55
, pp. 370-76
-
-
Schmitt, F.A.1
Davis, D.G.2
Wekstein, D.R.3
-
29
-
-
0025863618
-
Neuropathological staging of alzheimer-related changes
-
Braak H, Braak E. Neuropathological staging of Alzheimer-related changes. Acta Neuropathol 1991;82:239-59
-
(1991)
Acta Neuropathol
, vol.82
, pp. 239-59
-
-
Braak, H.1
Braak, E.2
-
30
-
-
0032749171
-
Application of the national institute on aging (nia)yreagan institute criteria for the neuropathological diagnosis of alzheimer disease
-
Newell KL, Hyman BT, Growdon JH, Hedley-Whyte ET. Application of the National Institute on Aging (NIA)YReagan Institute criteria for the neuropathological diagnosis of Alzheimer disease. J Neuropathol Exp Neurol 1999;58:1147-55
-
(1999)
J Neuropathol Exp Neurol
, vol.58
, pp. 1147-55
-
-
Newell, K.L.1
Hyman, B.T.2
Growdon, J.H.3
Hedley-Whyte, E.T.4
-
31
-
-
0030700593
-
The cerad neuropathology protocol and consensus recommendations for the postmortem diagnosis of alzheimer's disease: A commentary
-
Mirra SS. The CERAD neuropathology protocol and consensus recommendations for the postmortem diagnosis of Alzheimer's disease: A commentary. Neurobiol Aging 1997;18:S91-94
-
(1997)
Neurobiol Aging
, vol.18
-
-
Mirra, S.S.1
-
32
-
-
4644268336
-
Reduction of cortical trka but not p75(ntr) protein in early-stage alzheimer's disease
-
Counts SE, Nadeem M, Wuu J, Ginsberg SD, Saragovi HU, Mufson EJ. Reduction of cortical TrkA but not p75(NTR) protein in early-stage Alzheimer's disease. Ann Neurol 2004;56:520-31
-
(2004)
Ann Neurol
, vol.56
, pp. 520-31
-
-
Counts, S.E.1
Nadeem, M.2
Wuu, J.3
Ginsberg, S.D.4
Saragovi, H.U.5
Mufson, E.J.6
-
33
-
-
2942536284
-
Increased prongf levels in subjects with mild cognitive impairment and mild alzheimer disease
-
Peng S, Wuu J, Mufson EJ, Fahnestock M. Increased proNGF levels in subjects with mild cognitive impairment and mild Alzheimer disease. J Neuropathol Exp Neurol 2004;63:641-49
-
(2004)
J Neuropathol Exp Neurol
, vol.63
, pp. 641-49
-
-
Peng, S.1
Wuu, J.2
Mufson, E.J.3
Fahnestock, M.4
-
34
-
-
77949826581
-
Deletion of m1 muscarinic acetylcholine receptors increases amyloid pathology in vitro and in vivo
-
Davis AA, Fritz JJ, Wess J, Lah JJ, Levey AI. Deletion of M1 muscarinic acetylcholine receptors increases amyloid pathology in vitro and in vivo. J Neurosci 2010;30:4190-96
-
(2010)
J Neurosci
, vol.30
, pp. 4190-96
-
-
Davis, A.A.1
Fritz, J.J.2
Wess, J.3
Lah, J.J.4
Levey, A.I.5
-
35
-
-
84860217505
-
Hippocampal drebrin loss in mild cognitive impairment
-
Counts SE, He B, Nadeem M, Wuu J, Scheff SW, Mufson EJ. Hippocampal drebrin loss in mild cognitive impairment. Neurodegener Dis 2012;10:216-19
-
(2012)
Neurodegener Dis
, vol.10
, pp. 216-19
-
-
Counts, S.E.1
He, B.2
Nadeem, M.3
Wuu, J.4
Scheff, S.W.5
Mufson, E.J.6
-
36
-
-
4644268336
-
Reduction of cortical trka but not p75(ntr) protein in early-stage alzheimer's disease
-
Counts SE, Nadeem M, Wuu J, Ginsberg SD, Saragovi HU, Mufson EJ. Reduction of cortical TrkA but not p75(NTR) protein in early-stage Alzheimer's disease. Ann Neurol 2004;56:520-31
-
(2004)
Ann Neurol
, vol.56
, pp. 520-31
-
-
Counts, S.E.1
Nadeem, M.2
Wuu, J.3
Ginsberg, S.D.4
Saragovi, H.U.5
Mufson, E.J.6
-
37
-
-
78650803250
-
Regional selectivity of rab5 and rab7 protein upregulation in mild cognitive impairment and alzheimer's disease
-
Ginsberg SD, Mufson EJ, Counts SE, et al. Regional selectivity of rab5 and rab7 protein upregulation in mild cognitive impairment and Alzheimer's disease. J Alzheimers Dis 2010;22:631-39
-
(2010)
J Alzheimers Dis
, vol.22
, pp. 631-39
-
-
Ginsberg, S.D.1
Mufson, E.J.2
Counts, S.E.3
-
38
-
-
0024364769
-
Altered levels of microtubule proteins in brains of alzheimer's disease patients
-
Nieto A, Montejo de Garcini E, Avila J. Altered levels of microtubule proteins in brains of Alzheimer's disease patients. Acta Neuropathol 1989;78:47-51
-
(1989)
Acta Neuropathol
, vol.78
, pp. 47-51
-
-
Nieto, A.1
Montejo De Garcini, E.2
Avila, J.3
-
39
-
-
0034656234
-
Selective regional loss of exocytotic presynaptic vesicle proteins in alzheimer's disease brains
-
Sze CI, Bi H, Kleinschmidt-DeMasters BK, Filley CM, Martin LJ. Selective regional loss of exocytotic presynaptic vesicle proteins in Alzheimer's disease brains. J Neurol Sci 2000;175:81-90
-
(2000)
J Neurol Sci
, vol.175
, pp. 81-90
-
-
Sze, C.I.1
Bi, H.2
Kleinschmidt-DeMasters, B.K.3
Filley, C.M.4
Martin, L.J.5
-
41
-
-
0003431468
-
-
3rd Ed. Pacific Grove CA: Duxbury Press
-
Kleinbaum DG, Kupper LL, Muller KE, Nizam A. Applied Regression Analysis and Other Multivariable Methods. 3rd ed. Pacific Grove, CA: Duxbury Press, 1998
-
(1998)
Applied Regression Analysis, Other Multivariable Methods
-
-
Kleinbaum, D.G.1
Kupper, L.L.2
Muller, K.E.3
Nizam, A.4
-
43
-
-
0027276502
-
Ngf level of is not decreased in the serum, brain-spinal fluid, hippocampus, or parietal cortex of individuals with alzheimer's disease
-
Murase K, Nabeshima T, Robitaille Y, Quirion R, Ogawa M, Hayashi K. NGF level of is not decreased in the serum, brain-spinal fluid, hippocampus, or parietal cortex of individuals with Alzheimer's disease. Biochem Biophys Res Commun 1993;193:198-203
-
(1993)
Biochem Biophys Res Commun
, vol.193
, pp. 198-203
-
-
Murase, K.1
Nabeshima, T.2
Robitaille, Y.3
Quirion, R.4
Ogawa, M.5
Hayashi, K.6
-
44
-
-
0043025510
-
Preservation of brain nerve growth factor in mild cognitive impairment and alzheimer disease
-
Mufson EJ, Ikonomovic MD, Styren SD, et al. Preservation of brain nerve growth factor in mild cognitive impairment and Alzheimer disease. Arch Neurol 2003;60:1143-48
-
(2003)
Arch Neurol
, vol.60
, pp. 1143-48
-
-
Mufson, E.J.1
Ikonomovic, M.D.2
Styren, S.D.3
-
45
-
-
13244288122
-
Pro-ngf isolated from the human brain affected by alzheimer's disease induces neuronal apoptosis mediated by p75ntr
-
Pedraza CE, Podlesniy P, Vidal N, et al. Pro-NGF isolated from the human brain affected by Alzheimer's disease induces neuronal apoptosis mediated by p75NTR. Am J Pathol 2005;166:533-43
-
(2005)
Am J Pathol
, vol.166
, pp. 533-43
-
-
Pedraza, C.E.1
Podlesniy, P.2
Vidal, N.3
-
46
-
-
33745700716
-
Pro-ngf from alzheimer's disease and normal human brain displays distinctive abilities to induce processing and nuclear translocation of intracellular domain of p75ntr and apoptosis
-
Podlesniy P, Kichev A, Pedraza C, et al. Pro-NGF from Alzheimer's disease and normal human brain displays distinctive abilities to induce processing and nuclear translocation of intracellular domain of p75NTR and apoptosis. Am J Pathol 2006;169:119-31
-
(2006)
Am J Pathol
, vol.169
, pp. 119-31
-
-
Podlesniy, P.1
Kichev, A.2
Pedraza, C.3
-
47
-
-
36549060136
-
Prongf, sortilin, and age-related neurodegeneration
-
Al-Shawi R, Hafner A, Chun S, et al. ProNGF, sortilin, and age-related neurodegeneration. Ann N Y Acad Sci 2007;1119:208-15
-
(2007)
Ann N Y Acad Sci
, vol.1119
, pp. 208-15
-
-
Al-Shawi, R.1
Hafner, A.2
Chun, S.3
-
48
-
-
42049088076
-
Neurotoxic and neurotrophic roles of prongf and the receptor sortilin in the adult and ageing nervous system
-
Al-Shawi R, Hafner A, Olsen J, et al. Neurotoxic and neurotrophic roles of proNGF and the receptor sortilin in the adult and ageing nervous system. Eur J Neurosci 2008;27:2103-4
-
(2008)
Eur J Neurosci
, vol.27
, pp. 2103-4
-
-
Al-Shawi, R.1
Hafner, A.2
Olsen, J.3
-
49
-
-
76849093311
-
Preservation of cortical sortilin protein levels in mci and alzheimer's disease
-
Mufson EJ, Wuu J, Counts SE, Nykjaer A. Preservation of cortical sortilin protein levels in MCI and Alzheimer's disease. Neurosci Lett 2010; 471:129-33
-
(2010)
Neurosci Lett
, vol.471
, pp. 129-33
-
-
Mufson, E.J.1
Wuu, J.2
Counts, S.E.3
Nykjaer, A.4
-
50
-
-
16644378634
-
Multitasking by the p75 neurotrophin receptor: Sortilin things out?
-
Bronfman FC, Fainzilber M. Multitasking by the p75 neurotrophin receptor: Sortilin things out? EMBO Rep 2004;5:867-71
-
(2004)
EMBO Rep
, vol.5
, pp. 867-71
-
-
Bronfman, F.C.1
Fainzilber, M.2
-
51
-
-
67349154949
-
Nrh2 is a trafficking switch to regulate sortilin localization and permit proneurotrophin-induced cell death
-
Kim T, Hempstead BL. NRH2 is a trafficking switch to regulate sortilin localization and permit proneurotrophin-induced cell death. EMBO J 2009;28:1612-23
-
(2009)
EMBO J
, vol.28
, pp. 1612-23
-
-
Kim, T.1
Hempstead, B.L.2
-
52
-
-
33646241085
-
Activity-dependent release of precursor nerve growth factor, conversion to mature nerve growth factor, and its degradation by a protease cascade
-
Bruno MA, Cuello AC. Activity-dependent release of precursor nerve growth factor, conversion to mature nerve growth factor, and its degradation by a protease cascade. Proc Natl Acad Sci USA 2006;103: 6735-40
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 6735-40
-
-
Bruno, M.A.1
Cuello, A.C.2
-
54
-
-
84856986118
-
Impact of the ngf maturation and degradation pathway on the cortical cholinergic system phenotype
-
Allard S, Leon WC, Pakavathkumar P, Bruno MA, Ribeiro-da-Silva A, Cuello AC. Impact of the NGF maturation and degradation pathway on the cortical cholinergic system phenotype. J Neurosci 2012;32:2002-12
-
(2012)
J Neurosci
, vol.32
, pp. 12
-
-
Allard, S.1
Leon, W.C.2
Pakavathkumar, P.3
Bruno, M.A.4
Ribeiro-da-Silva, A.5
Cuello, A.C.6
-
55
-
-
84862903771
-
Increased expression of trkb and capzb2 accompanies preserved cognitive status in early alzheimer disease pathology
-
Kao PF, Banigan MG, Vanderburg CR, et al. Increased expression of TrkB and Capzb2 accompanies preserved cognitive status in early Alzheimer disease pathology. J Neuropathol Exp Neurol 2012;71:654-64
-
(2012)
J Neuropathol Exp Neurol
, vol.71
, pp. 654-64
-
-
Kao, P.F.1
Banigan, M.G.2
Vanderburg, C.R.3
-
56
-
-
78049427173
-
Microarray analysis of hippocampal ca1 neurons implicates early endosomal dysfunction during alzheimer's disease progression
-
Ginsberg SD, Alldred MJ, Counts SE, et al. Microarray analysis of hippocampal CA1 neurons implicates early endosomal dysfunction during Alzheimer's disease progression. Biol Psychiatry 2010;68:885-93
-
(2010)
Biol Psychiatry
, vol.68
, pp. 885-93
-
-
Ginsberg, S.D.1
Alldred, M.J.2
Counts, S.E.3
-
57
-
-
49949083479
-
Amyloid beta-peptide levels in laser capture microdissected cornu ammonis 1 pyramidal neurons of alzheimer's brain
-
Aoki M, Volkmann I, Tjernberg LO, Winblad B, Bogdanovic N. Amyloid beta-peptide levels in laser capture microdissected cornu ammonis 1 pyramidal neurons of Alzheimer's brain. Neuroreport 2008;19:1085-89
-
(2008)
Neuroreport
, vol.19
, pp. 1085-89
-
-
Aoki, M.1
Volkmann, I.2
Tjernberg, L.O.3
Winblad, B.4
Bogdanovic, N.5
-
58
-
-
80051520187
-
Precuneus amyloid burden is associated with reduced cholinergic activity in alzheimer disease
-
Ikonomovic MD, Klunk WE, Abrahamson EE, et al. Precuneus amyloid burden is associated with reduced cholinergic activity in Alzheimer disease. Neurology 2011;77:39-47
-
(2011)
Neurology
, vol.77
, pp. 39-47
-
-
Ikonomovic, M.D.1
Klunk, W.E.2
Abrahamson, E.E.3
-
59
-
-
0035135841
-
Protein kinase sgk mediates survival signals by phosphorylating the forkhead transcription factor fkhrl1 (foxo3a)
-
Brunet A, Park J, Tran H, Hu LS, Hemmings BA, Greenberg ME. Protein kinase SGK mediates survival signals by phosphorylating the forkhead transcription factor FKHRL1 (FOXO3a). Mol Cell Biol 2001;21:952-65
-
(2001)
Mol Cell Biol
, vol.21
, pp. 952-65
-
-
Brunet, A.1
Park, J.2
Tran, H.3
Hu, L.S.4
Hemmings, B.A.5
Greenberg, M.E.6
-
60
-
-
84859718265
-
Demonstrated brain insulin resistance in alzheimer's disease patients is associated with igf-1 resistance, irs-1 dysregulation, and cognitive decline
-
Talbot K, Wang HY, Kazi H, et al. Demonstrated brain insulin resistance in Alzheimer's disease patients is associated with IGF-1 resistance, IRS-1 dysregulation, and cognitive decline. J Clin Invest 2012;122:1316-38
-
(2012)
J Clin Invest
, vol.122
, pp. 1316-38
-
-
Talbot, K.1
Wang, H.Y.2
Kazi, H.3
-
61
-
-
17144395975
-
The activation of akt/pkb signaling pathway and cell survival
-
Song G, Ouyang G, Bao S. The activation of Akt/PKB signaling pathway and cell survival. J Cell Mol Med 2005;9:59-71
-
(2005)
J Cell Mol Med
, vol.9
, pp. 59-71
-
-
Song, G.1
Ouyang, G.2
Bao, S.3
-
62
-
-
0036344505
-
Neurotrophin signaling through the p75 neurotrophin receptor
-
Roux PP, Barker PA. Neurotrophin signaling through the p75 neurotrophin receptor. Prog Neurobiol 2002;67:203-33
-
(2002)
Prog Neurobiol
, vol.67
, pp. 203-33
-
-
Roux, P.P.1
Barker, P.A.2
-
63
-
-
55849111494
-
Cholinergic system during the progression of alzheimer's disease: Therapeutic implications
-
Mufson EJ, Counts SE, Perez SE, Ginsberg SD. Cholinergic system during the progression of Alzheimer's disease: Therapeutic implications. Exp Rev Neurother 2008;8:1703-18
-
(2008)
Exp Rev Neurother
, vol.8
, pp. 1703-18
-
-
Mufson, E.J.1
Counts, S.E.2
Perez, S.E.3
Ginsberg, S.D.4
-
64
-
-
0034797352
-
Differential activation of neuronal erk jnksapk and p38 in alzheimer disease: The ''two hit'' hypothesis
-
Zhu X, Castellani RJ, Takeda A, et al. Differential activation of neuronal ERK, JNK/SAPK and p38 in Alzheimer disease: The ''two hit'' hypothesis. Mech Ageing Dev 2001;123:39-46
-
(2001)
Mech Ageing Dev
, vol.123
, pp. 39-46
-
-
Zhu, X.1
Castellani, R.J.2
Takeda, A.3
-
65
-
-
80055022386
-
Progression of tau pathology in cholinergic basal forebrain neurons in mild cognitive impairment and alzheimer's disease
-
Vana L, Kanaan NM, Ugwu IC, Wuu J, Mufson EJ, Binder LI. Progression of tau pathology in cholinergic basal forebrain neurons in mild cognitive impairment and Alzheimer's disease. Am J Pathol 2011;179: 2533-50
-
(2011)
Am J Pathol
, vol.179
, pp. 2533-50
-
-
Vana, L.1
Kanaan, N.M.2
Ugwu, I.C.3
Wuu, J.4
Mufson, E.J.5
Binder, L.I.6
-
66
-
-
33646392455
-
Neuropathologic features of amnestic mild cognitive impairment
-
Petersen RC, Parisi JE, Dickson DW, et al. Neuropathologic features of amnestic mild cognitive impairment. Arch Neurol 2006;63:665-72
-
(2006)
Arch Neurol
, vol.63
, pp. 665-72
-
-
Petersen, R.C.1
Parisi, J.E.2
Dickson, D.W.3
-
67
-
-
67349184808
-
Neuropathology of nondemented aging: Presumptive evidence for preclinical alzheimer disease
-
Price JL, McKeel DW Jr., Buckles VD, et al. Neuropathology of nondemented aging: Presumptive evidence for preclinical Alzheimer disease. Neurobiol Aging 2009;30:1026-36
-
(2009)
Neurobiol Aging
, vol.30
, pp. 1026-36
-
-
Price, J.L.1
McKeel Jr., D.W.2
Buckles, V.D.3
-
68
-
-
27444439471
-
Mild cognitive impairment in different functional domains and incident alzheimer's disease
-
Aggarwal NT, Wilson RS, Beck TL, Bienias JL, Bennett DA. Mild cognitive impairment in different functional domains and incident Alzheimer's disease. J Neurol Neurosurg Psychiatry 2005;76:1479-84
-
(2005)
J Neurol Neurosurg Psychiatry
, vol.76
, pp. 1479-84
-
-
Aggarwal, N.T.1
Wilson, R.S.2
Beck, T.L.3
Bienias, J.L.4
Bennett, D.A.5
-
69
-
-
39549112686
-
Memory impairment, executive dysfunction, and intellectual decline in preclinical alzheimer's disease
-
Grober E, Hall CB, Lipton RB, Zonderman AB, Resnick SM, Kawas C. Memory impairment, executive dysfunction, and intellectual decline in preclinical Alzheimer's disease. J Int Neuropsychol Soc 2008;14:266-78
-
(2008)
J Int Neuropsychol Soc
, vol.14
, pp. 266-78
-
-
Grober, E.1
Hall, C.B.2
Lipton, R.B.3
Zonderman, A.B.4
Resnick, S.M.5
Kawas, C.6
-
70
-
-
66549127860
-
Episodic memory loss is related to hippocampal-mediated beta-amyloid deposition in elderly subjects
-
Mormino EC, Kluth JT, Madison CM, et al. Episodic memory loss is related to hippocampal-mediated beta-amyloid deposition in elderly subjects. Brain 2009;132:1310-23
-
(2009)
Brain
, vol.132
, pp. 1310-23
-
-
Mormino, E.C.1
Kluth, J.T.2
Madison, C.M.3
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