cAMP-responsive element modulator α (CREMα) contributes to decreased notch-1 expression in T cells from patients with active systemic lupus erythematosus (SLE)

Journal of Biological Chemistry

Volumn 287, Issue 51, 2012, Pages 42525-42532

  Rauen, Thomas ^a,b   Grammatikos, Alexandros P ^a   Hedrich, Christian M ^a   Floege, Jürgen ^b   Tenbrock, Klaus ^b   Ohl, Kim ^b   Kyttaris, Vasileios C ^a   Tsokos, George C ^a  

^a BETH ISRAEL DEACONESS MEDICAL CENTER   (United States)

^b RWTH AACHEN UNIVERSITY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

DNA METHYLATION; GENE TRANSCRIPTIONS; HISTONE H3; KEY REGULATORS; MOLECULAR MECHANISM; NOTCH SIGNALING; PROMOTER ACTIVITIES; PROTEIN LEVEL; RECEPTOR EXPRESSION; SYSTEMIC LUPUS ERYTHEMATOSUS; T CELL RECEPTOR; T CELLS; T LYMPHOCYTES;

ALKYLATION; CELL MEMBRANES; CELL PROLIFERATION; GENES; NUCLEIC ACIDS; TRANSCRIPTION;

CYTOLOGY;

CYCLIC AMP RESPONSIVE ELEMENT MODULATOR; CYCLIC AMP RESPONSIVE ELEMENT MODULATOR ALPHA; HISTONE H3; INTERLEUKIN 17; MESSENGER RNA; NOTCH1 RECEPTOR; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DNA METHYLATION; GENE CONTROL; GENE EXPRESSION REGULATION; HISTONE METHYLATION; HUMAN; HUMAN CELL; IMMUNOPATHOGENESIS; MOUSE; NONHUMAN; NOTCH 1 GENE; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN FUNCTION; SYSTEMIC LUPUS ERYTHEMATOSUS; T LYMPHOCYTE SUBPOPULATION; TRANSCRIPTION TERMINATION; UPREGULATION;

ANIMALS; CASE-CONTROL STUDIES; CELL MEMBRANE; CPG ISLANDS; CYCLIC AMP RESPONSE ELEMENT MODULATOR; DNA METHYLATION; FEMALE; GENE EXPRESSION REGULATION; HISTONES; HUMANS; INTERLEUKIN-17; JURKAT CELLS; LUPUS ERYTHEMATOSUS, SYSTEMIC; MICE; PROMOTER REGIONS, GENETIC; PROTEIN BINDING; RECEPTOR, NOTCH1; RNA, MESSENGER; T-LYMPHOCYTES; TRANSCRIPTION, GENETIC;

EID: 84871115674     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.425371     Document Type: Article

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