-
1
-
-
58749084365
-
Deaths among drug addicts in Eastern Denmark 2005
-
Pedersen, C.L., Steentoft, A., Kringsholm, B. (2008) Deaths among drug addicts in Eastern Denmark 2005. Ugeskr Laeger, 170, 4124-4127.
-
(2008)
Ugeskr Laeger
, vol.170
, pp. 4124-4127
-
-
Pedersen, C.L.1
Steentoft, A.2
Kringsholm, B.3
-
2
-
-
0142228151
-
Substitutions therapy of opiate addiction in Denmark
-
Ishoy, T., Iversen, C. (2003) Substitutions therapy of opiate addiction in Denmark. Ugeskr Laeger, 165, 3620-3623.
-
(2003)
Ugeskr Laeger
, vol.165
, pp. 3620-3623
-
-
Ishoy, T.1
Iversen, C.2
-
3
-
-
67650491596
-
Methadone-induced mortality in the treatment of chronic pain: Role of QT prolongation
-
Andrews, C.M., Krantz, M.J., Wedam, E.F., Marcuson, M.J., Capacchione, J.F., Haigney, M.C. (2009) Methadone-induced mortality in the treatment of chronic pain: Role of QT prolongation. Cardiology Journal, 16, 210-217.
-
(2009)
Cardiology Journal
, vol.16
, pp. 210-217
-
-
Andrews, C.M.1
Krantz, M.J.2
Wedam, E.F.3
Marcuson, M.J.4
Capacchione, J.F.5
Haigney, M.C.6
-
4
-
-
0028970418
-
The mu1, mu2, delta, kappa opioid receptor binding profiles of methadone stereoisomers and morphine
-
Kristensen, K., Christensen, C.B., Christrup, L.L. (1995) The mu1, mu2, delta, kappa opioid receptor binding profiles of methadone stereoisomers and morphine. Life Science, 56, L45-L50.
-
(1995)
Life Science
, vol.56
-
-
Kristensen, K.1
Christensen, C.B.2
Christrup, L.L.3
-
5
-
-
0036439851
-
Interindividual variability of the clinical pharmacokinetics of methadone: Implications for the treatment of opioid dependence
-
Eap, C.B., Buclin, T., Baumann, P. (2002) Interindividual variability of the clinical pharmacokinetics of methadone: Implications for the treatment of opioid dependence. Clinical Pharmacokinetics, 41, 1153-1193.
-
(2002)
Clinical Pharmacokinetics
, vol.41
, pp. 1153-1193
-
-
Eap, C.B.1
Buclin, T.2
Baumann, P.3
-
6
-
-
0034704455
-
Plasma concentrations of the enantiomers of methadone and therapeutic response in methadone maintenance treatment
-
Eap, C.B., Bourquin, M., Martin, J., Spagnoli, J., Livoti, S., Powell, K. et al.; (2000) Plasma concentrations of the enantiomers of methadone and therapeutic response in methadone maintenance treatment. Drug and Alcohol Dependence, 61, 47-54.
-
(2000)
Drug and Alcohol Dependence
, vol.61
, pp. 47-54
-
-
Eap, C.B.1
Bourquin, M.2
Martin, J.3
Spagnoli, J.4
Livoti, S.5
Powell, K.6
-
7
-
-
0029132157
-
Pharmacokinetics of methadone and its primary metabolite in 20 opiate addicts
-
de Vos, J.W., Geerlings, P.J., van den Brink, W., Ufkes, J.G., van Wilgenburg, H. (1995) Pharmacokinetics of methadone and its primary metabolite in 20 opiate addicts. European Journal of Clinical Pharmacology, 48, 361-366.
-
(1995)
European Journal of Clinical Pharmacology
, vol.48
, pp. 361-366
-
-
de Vos, J.W.1
Geerlings, P.J.2
van den Brink, W.3
Ufkes, J.G.4
van Wilgenburg, H.5
-
8
-
-
0033632124
-
Toxicology and pathology of deaths related to methadone: Retrospective review
-
Karch, S.B., Stephens, B.G. (2000) Toxicology and pathology of deaths related to methadone: Retrospective review. Western Journal of Medicine, 172, 11-14.
-
(2000)
Western Journal of Medicine
, vol.172
, pp. 11-14
-
-
Karch, S.B.1
Stephens, B.G.2
-
9
-
-
0033747394
-
Steady-state pharmacokinetics of (R)- and (S)-methadone in methadone maintenance patients
-
Foster, D.J., Somogyi, A.A., Dyer, K.R., White, J.M., Bochner, F. (2000) Steady-state pharmacokinetics of (R)- and (S)-methadone in methadone maintenance patients. British Journal of Clinical Pharmacology, 50, 427-440.
-
(2000)
British Journal of Clinical Pharmacology
, vol.50
, pp. 427-440
-
-
Foster, D.J.1
Somogyi, A.A.2
Dyer, K.R.3
White, J.M.4
Bochner, F.5
-
10
-
-
17444421220
-
Determination of total and free concentrations of the enantiomers of methadone and its metabolite(2-ethylidene-1,5-dimethyl-3,3-diphenyl-pyrrolidine) in human plasma by enantioselective liquid chromatography with mass spectrometric detection
-
Rodriguez-Rosas, M.E., Medrano, J.G., Epstein, D.H., Moolchan, E.T., Preston, K.L., Wainer, I.W. (2005) Determination of total and free concentrations of the enantiomers of methadone and its metabolite(2-ethylidene-1,5-dimethyl-3,3-diphenyl-pyrrolidine) in human plasma by enantioselective liquid chromatography with mass spectrometric detection. Journal of Chromatography A, 1073, 237-248.
-
(2005)
Journal of Chromatography A
, vol.1073
, pp. 237-248
-
-
Rodriguez-Rosas, M.E.1
Medrano, J.G.2
Epstein, D.H.3
Moolchan, E.T.4
Preston, K.L.5
Wainer, I.W.6
-
11
-
-
67650488215
-
Validation and long-term evaluation of a modified on-line chiral analytical method for therapeutic drug monitoring of (R,S)-methadone in clinical samples
-
Ansermot, N., Rudaz, S., Brawand-Amey, M., Fleury-Souverain, S., Veuthey, J.L., Eap, C.B. (2009) Validation and long-term evaluation of a modified on-line chiral analytical method for therapeutic drug monitoring of (R,S)-methadone in clinical samples. Journal of Chromatography B, 877, 2301-2307.
-
(2009)
Journal of Chromatography B
, vol.877
, pp. 2301-2307
-
-
Ansermot, N.1
Rudaz, S.2
Brawand-Amey, M.3
Fleury-Souverain, S.4
Veuthey, J.L.5
Eap, C.B.6
-
12
-
-
29144536234
-
Determination of free and protein-bound methadone and its major metabolite EDDP: Enantiomeric separation and quantitation by LC/MS/MS
-
Etter, M.L., George, S., Graybiel, K., Eichhorst, J., Lehotay, D.C. (2005) Determination of free and protein-bound methadone and its major metabolite EDDP: Enantiomeric separation and quantitation by LC/MS/MS. Clinical Biochemistry, 38, 1095-1102.
-
(2005)
Clinical Biochemistry
, vol.38
, pp. 1095-1102
-
-
Etter, M.L.1
George, S.2
Graybiel, K.3
Eichhorst, J.4
Lehotay, D.C.5
-
13
-
-
41649103033
-
An enantiomer-selective liquid chromatography-tandem mass spectrometry method for methadone and EDDP validated for use in human plasma, urine, and liver microsomes
-
Moody, D.E., Lin, S.N., Chang, Y., Lamm, L., Greenwald, M.K., Ahmed, M.S. (2008) An enantiomer-selective liquid chromatography-tandem mass spectrometry method for methadone and EDDP validated for use in human plasma, urine, and liver microsomes. Journal of Analytical Toxicology, 32, 208-219.
-
(2008)
Journal of Analytical Toxicology
, vol.32
, pp. 208-219
-
-
Moody, D.E.1
Lin, S.N.2
Chang, Y.3
Lamm, L.4
Greenwald, M.K.5
Ahmed, M.S.6
-
14
-
-
2542417962
-
Method development and validation for quantitative determination of methadone enantiomers in human plasma by liquid chromatography/tandem mass spectrometry
-
Liang, H.R., Foltz, R.L., Meng, M., Bennett, P. (2004) Method development and validation for quantitative determination of methadone enantiomers in human plasma by liquid chromatography/tandem mass spectrometry. Journal of Chromatography B, 806, 191-198.
-
(2004)
Journal of Chromatography B
, vol.806
, pp. 191-198
-
-
Liang, H.R.1
Foltz, R.L.2
Meng, M.3
Bennett, P.4
-
15
-
-
0034424764
-
Development and application of a chiral high performance liquid chromatography assay for pharmacokinetic studies of methadone
-
Boulton, D.W., DeVane, C.L. (2000) Development and application of a chiral high performance liquid chromatography assay for pharmacokinetic studies of methadone. Chirality, 12, 681-687.
-
(2000)
Chirality
, vol.12
, pp. 681-687
-
-
Boulton, D.W.1
DeVane, C.L.2
-
16
-
-
11844268080
-
Chiral analysis of methadone and its major metabolites (EDDP and EMDP) by liquid chromatography-mass spectrometry
-
Kelly, T., Doble, P., Dawson, M. (2005) Chiral analysis of methadone and its major metabolites (EDDP and EMDP) by liquid chromatography-mass spectrometry. Journal of Chromatography B, 814, 315-323.
-
(2005)
Journal of Chromatography B
, vol.814
, pp. 315-323
-
-
Kelly, T.1
Doble, P.2
Dawson, M.3
-
17
-
-
77953498774
-
Development of a method to measure methadone enantiomers and its metabolites without enantiomer standard compounds for the plasma of methadone maintenance patients
-
Wang, S.C., Ho, I.K., Wu, S.L., Liu, S.C., Kuo, H.W., Lin, K.M. et al. (2010) Development of a method to measure methadone enantiomers and its metabolites without enantiomer standard compounds for the plasma of methadone maintenance patients. Biomedical Chromatography, 24, 782-788.
-
(2010)
Biomedical Chromatography
, vol.24
, pp. 782-788
-
-
Wang, S.C.1
Ho, I.K.2
Wu, S.L.3
Liu, S.C.4
Kuo, H.W.5
Lin, K.M.6
-
18
-
-
44649170541
-
Validation of chiral capillary electrophoresis-electrospray ionization-mass spectrometry methods for ecstasy and methadone in plasma
-
Schappler, J., Guillarme, D., Prat, J., Veuthey, J.L., Rudaz, S. (2008) Validation of chiral capillary electrophoresis-electrospray ionization-mass spectrometry methods for ecstasy and methadone in plasma. Electrophoresis, 29, 2193-2202.
-
(2008)
Electrophoresis
, vol.29
, pp. 2193-2202
-
-
Schappler, J.1
Guillarme, D.2
Prat, J.3
Veuthey, J.L.4
Rudaz, S.5
-
19
-
-
34047205102
-
Stereoselective determination of methadone and its main metabolite in serum and urine from methadone maintenance patients
-
Valentova, J., Horakova, R., Pechova, I., Okruhlica, L., Devinsky, F. (2006) Stereoselective determination of methadone and its main metabolite in serum and urine from methadone maintenance patients. Neurology and Endocrinology Letters, 27, 130-133.
-
(2006)
Neurology and Endocrinology Letters
, vol.27
, pp. 130-133
-
-
Valentova, J.1
Horakova, R.2
Pechova, I.3
Okruhlica, L.4
Devinsky, F.5
-
20
-
-
33746846139
-
Stereoselective quantification of methadone and a d(6)-labeled isotopomer using high performance liquid chromatography-atmospheric pressure chemical ionization massspectrometry: Application to a pharmacokinetic study in a methadone maintained subject
-
Foster, D.J., Morton, E.B., Heinkele, G., Murdter, T.E., Somogyi, A.A. (2006) Stereoselective quantification of methadone and a d(6)-labeled isotopomer using high performance liquid chromatography-atmospheric pressure chemical ionization massspectrometry: Application to a pharmacokinetic study in a methadone maintained subject. Therapeutic Drug Monitoring, 28, 559-567.
-
(2006)
Therapeutic Drug Monitoring
, vol.28
, pp. 559-567
-
-
Foster, D.J.1
Morton, E.B.2
Heinkele, G.3
Murdter, T.E.4
Somogyi, A.A.5
-
21
-
-
0033053569
-
Development of validated stereoselective methods for methadone determination in clinical samples
-
Rudaz, S., Ortelli, D., Gex-Fabry, M., Deglon, J.J., Balant, L., Veuthey, J.L. (1999) Development of validated stereoselective methods for methadone determination in clinical samples. Chirality, 11, 487-494.
-
(1999)
Chirality
, vol.11
, pp. 487-494
-
-
Rudaz, S.1
Ortelli, D.2
Gex-Fabry, M.3
Deglon, J.J.4
Balant, L.5
Veuthey, J.L.6
-
22
-
-
0032970906
-
Enantioselective highperformance liquid chromatographic method for the determination of methadone and its main metabolite in urine using an AGP and a C8 column coupled serially
-
Angelo, H.R., Beck, N., Kristensen, K. (1999) Enantioselective highperformance liquid chromatographic method for the determination of methadone and its main metabolite in urine using an AGP and a C8 column coupled serially. Journal of Chromatography B, 724, 35-40.
-
(1999)
Journal of Chromatography B
, vol.724
, pp. 35-40
-
-
Angelo, H.R.1
Beck, N.2
Kristensen, K.3
-
23
-
-
0030696579
-
Enantioselective high-performance liquid chromatography determination of methadone enantiomers and its major metabolite in human biological fluids using a new derivatized cyclodextrin-bonded phase
-
Pham-Huy, C., Chikhi-Chorfi, N., Galons, H., Sadeg, N., Laqueille, X., Aymard, N. et al. (1997) Enantioselective high-performance liquid chromatography determination of methadone enantiomers and its major metabolite in human biological fluids using a new derivatized cyclodextrin-bonded phase. Journal of Chromatography B, 700, 155-163.
-
(1997)
Journal of Chromatography B
, vol.700
, pp. 155-163
-
-
Pham-Huy, C.1
Chikhi-Chorfi, N.2
Galons, H.3
Sadeg, N.4
Laqueille, X.5
Aymard, N.6
-
24
-
-
2342574141
-
Brain penetration of methadone (R)- and (S)-enantiomers is greatly increased by P-glycoprotein deficiency in the blood-brain barrier of Abcb1a gene knockout mice
-
Wang, J.S., Ruan, Y., Taylor, R.M., Donovan, J.L., Markowitz, J.S., DeVane, C.L. (2004) Brain penetration of methadone (R)- and (S)-enantiomers is greatly increased by P-glycoprotein deficiency in the blood-brain barrier of Abcb1a gene knockout mice. Psychopharmacology (Berlin), 173, 132-138.
-
(2004)
Psychopharmacology (Berlin)
, vol.173
, pp. 132-138
-
-
Wang, J.S.1
Ruan, Y.2
Taylor, R.M.3
Donovan, J.L.4
Markowitz, J.S.5
DeVane, C.L.6
-
25
-
-
34250342562
-
A validated liquid chromatography-atmospheric pressure chemical ionization-tandem mass spectrometric method for the quantification of methadone, 2-ethylidene-1,5-dimethyl-3,3-diphenylpyrrolidine (EDDP), and 2-Ethyl-5-methyl-3,3-diphenylpyroline (EMDP) in human breast milk
-
Choo, R.E., Jansson, L.M., Scheidweiler, K., Huestis, M.A. (2007) A validated liquid chromatography-atmospheric pressure chemical ionization-tandem mass spectrometric method for the quantification of methadone, 2-ethylidene-1,5-dimethyl-3,3-diphenylpyrrolidine (EDDP), and 2-Ethyl-5-methyl-3,3-diphenylpyroline (EMDP) in human breast milk. Journal of Analytical Toxicology, 31, 265-269.
-
(2007)
Journal of Analytical Toxicology
, vol.31
, pp. 265-269
-
-
Choo, R.E.1
Jansson, L.M.2
Scheidweiler, K.3
Huestis, M.A.4
-
26
-
-
79952109552
-
Quantification of methadone and its metabolite 2-ethylidene-1,5-dimethyl-3,3-diphenylpyrrolidine in third instar larvae of Lucilia sericata (Diptera: Calliphoridae) using liquid chromatography-tandem mass spectrometry
-
Gosselin, M., Ramirez Fernandez, M.M., Wille, S.M., Samyn, N., De, B.G., Bourel, B. (2010) Quantification of methadone and its metabolite 2-ethylidene-1,5-dimethyl-3,3-diphenylpyrrolidine in third instar larvae of Lucilia sericata (Diptera: Calliphoridae) using liquid chromatography-tandem mass spectrometry. Journal of Analytical Toxicology, 34, 374-380.
-
(2010)
Journal of Analytical Toxicology
, vol.34
, pp. 374-380
-
-
Gosselin, M.1
Ramirez Fernandez, M.M.2
Wille, S.M.3
Samyn, N.4
De, B.G.5
Bourel, B.6
-
27
-
-
0026665674
-
Solid-phase extraction of drugs from biological tissues-A review
-
Scheurer, J., Moore, C.M. (1992) Solid-phase extraction of drugs from biological tissues-A review. Journal of Analytical Toxicology, 16, 264-269.
-
(1992)
Journal of Analytical Toxicology
, vol.16
, pp. 264-269
-
-
Scheurer, J.1
Moore, C.M.2
-
29
-
-
50949101198
-
Chiral analysis of methadone and its main metabolite EDDP in postmortem blood by liquid chromatography-mass spectrometry
-
Johansen, S.S., Linnet, K. (2008) Chiral analysis of methadone and its main metabolite EDDP in postmortem blood by liquid chromatography-mass spectrometry. Journal of Analytical Toxicology, 32, 499-504.
-
(2008)
Journal of Analytical Toxicology
, vol.32
, pp. 499-504
-
-
Johansen, S.S.1
Linnet, K.2
-
30
-
-
84864540850
-
Validation of a fully automated robotic setup for preparation of whole blood samples for LC-MS toxicology analysis
-
Andersen, D., Rasmussen, B.S., Linnet, K. Validation of a fully automated robotic setup for preparation of whole blood samples for LC-MS toxicology analysis. Journal of Analytical Toxicology, 36, 280-287.
-
Journal of Analytical Toxicology
, vol.36
, pp. 280-287
-
-
Andersen, D.1
Rasmussen, B.S.2
Linnet, K.3
-
31
-
-
33645224920
-
Liquid chromatography-mass spectrometry/mass spectrometry method development for drug metabolism studies: Examining lipid matrixionization effects in plasma
-
Little, J.L., Wempe, M.F., Buchanan, C.M. (2006) Liquid chromatography-mass spectrometry/mass spectrometry method development for drug metabolism studies: Examining lipid matrixionization effects in plasma. Journal of Chromatography B, 833, 219-230.
-
(2006)
Journal of Chromatography B
, vol.833
, pp. 219-230
-
-
Little, J.L.1
Wempe, M.F.2
Buchanan, C.M.3
-
32
-
-
33846075702
-
Validation of new methods
-
Peters, F.T., Drummer, O.H., Musshoff, F. (2007) Validation of new methods. Forensic Science International, 165, 216-224.
-
(2007)
Forensic Science International
, vol.165
, pp. 216-224
-
-
Peters, F.T.1
Drummer, O.H.2
Musshoff, F.3
-
33
-
-
77951257715
-
Determination of 19 drugs of abuse and metabolites in whole blood by high-performance liquid chromatography-tandem mass spectrometry
-
Bjork, M.K., Nielsen, M.K., Markussen, L.O., Klinke, H.B., Linnet, K. (2010) Determination of 19 drugs of abuse and metabolites in whole blood by high-performance liquid chromatography-tandem mass spectrometry. Analytical and Bioanalytical Chemistry, 396, 2393-2401.
-
(2010)
Analytical and Bioanalytical Chemistry
, vol.396
, pp. 2393-2401
-
-
Bjork, M.K.1
Nielsen, M.K.2
Markussen, L.O.3
Klinke, H.B.4
Linnet, K.5
-
34
-
-
0035092065
-
General unknown screening in postmortem tissue and blood samples: A semiautomatic solid-phase extraction using polystyrene resins followed by liquid-liquid extraction
-
Stimpfl, T., Jurenitsch, J., Vycudilik, W. (2001) General unknown screening in postmortem tissue and blood samples: A semiautomatic solid-phase extraction using polystyrene resins followed by liquid-liquid extraction. Journal of Analytical Toxicology, 25, 125-129.
-
(2001)
Journal of Analytical Toxicology
, vol.25
, pp. 125-129
-
-
Stimpfl, T.1
Jurenitsch, J.2
Vycudilik, W.3
-
35
-
-
32544449467
-
Fast gas chromatography/mass spectrometric assay for the validated quantitative determination of methadone and the primary metabolite EDDP in whole blood
-
Gunnar, T., Eskola, T., Lillsunde, P. (2006) Fast gas chromatography/mass spectrometric assay for the validated quantitative determination of methadone and the primary metabolite EDDP in whole blood. Rapid Communications in Mass Spectrometry, 20, 673-679.
-
(2006)
Rapid Communications in Mass Spectrometry
, vol.20
, pp. 673-679
-
-
Gunnar, T.1
Eskola, T.2
Lillsunde, P.3
-
36
-
-
32944457632
-
A validated positive chemical ionization GC/MS method for the identification and quantification of amphetamine, opiates, cocaine, and metabolites in human postmortem brain
-
Lowe, R.H., Barnes, A.J., Lehrmann, E., Freed, W.J., Kleinman, J.E., Hyde, T.M. et al. (2006) A validated positive chemical ionization GC/MS method for the identification and quantification of amphetamine, opiates, cocaine, and metabolites in human postmortem brain. Journal of Mass Spectrometry, 41, 175-184.
-
(2006)
Journal of Mass Spectrometry
, vol.41
, pp. 175-184
-
-
Lowe, R.H.1
Barnes, A.J.2
Lehrmann, E.3
Freed, W.J.4
Kleinman, J.E.5
Hyde, T.M.6
-
37
-
-
0029802715
-
Evaluation of a solidphase extraction procedure for the simultaneous determination of morphine, 6-monoacetylmorphine, codeine and dihydrocodeine in plasma and whole blood by GC/MS
-
Geier, A., Bergemann, D., von Meyer, L. (1996) Evaluation of a solidphase extraction procedure for the simultaneous determination of morphine, 6-monoacetylmorphine, codeine and dihydrocodeine in plasma and whole blood by GC/MS. International Journal of Legal Medicine, 109, 80-83.
-
(1996)
International Journal of Legal Medicine
, vol.109
, pp. 80-83
-
-
Geier, A.1
Bergemann, D.2
von Meyer, L.3
-
38
-
-
34347373034
-
Using environmental analytical data to estimate levels of community consumption of illicit drugs and abused pharmaceuticals
-
Bones, J., Thomas, K.V., Paull, B. (2007) Using environmental analytical data to estimate levels of community consumption of illicit drugs and abused pharmaceuticals. Journal of Environmental Monitoring Supplementary Information, 9, 701-707.
-
(2007)
Journal of Environmental Monitoring Supplementary Information
, vol.9
, pp. 701-707
-
-
Bones, J.1
Thomas, K.V.2
Paull, B.3
-
39
-
-
0020554496
-
Brain and plasma levels of methadone and their relationships to analgesic activity of methadone in rats
-
Liu, S.J., Roerig, D.L., Wang, R.I. (1983) Brain and plasma levels of methadone and their relationships to analgesic activity of methadone in rats. Drug Metabolism and Disposition, 11, 335-338.
-
(1983)
Drug Metabolism and Disposition
, vol.11
, pp. 335-338
-
-
Liu, S.J.1
Roerig, D.L.2
Wang, R.I.3
-
40
-
-
0015805471
-
Methadone in autopsy cases
-
Norheim, G. (1973) Methadone in autopsy cases. Z. Rechtsmed, 73, 219-224.
-
(1973)
Z. Rechtsmed
, vol.73
, pp. 219-224
-
-
Norheim, G.1
-
41
-
-
0017257556
-
Evaluation of the Abuscreen for methadone
-
Manning, T., Bidanset, J.H., Cohen, S., Lukash, L. (1976) Evaluation of the Abuscreen for methadone. Journal of Forensic Sciences, 21, 112-120.
-
(1976)
Journal of Forensic Sciences
, vol.21
, pp. 112-120
-
-
Manning, T.1
Bidanset, J.H.2
Cohen, S.3
Lukash, L.4
|