Pentoxifylline and propentofylline prevent proliferation and activation of the mammalian target of rapamycin and mitogen activated protein kinase in cultured spinal astrocytes

Journal of Neuroscience Research

Volumn 91, Issue 2, 2013, Pages 300-312

  Norsted Gregory, Ebba ^a   Delaney, Ada ^a   Abdelmoaty, Sally ^a   Bas, Duygu B ^a   Codeluppi, Simone ^a   Wigerblad, Gustaf ^a   Svensson, Camilla I ^a  

^a KAROLINSKA INSTITUTE   (Sweden)

Author keywords

Astrocyte activation; Cytokines; Glia; MAPK; Methyl xanthenes

Indexed keywords

4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; ANTHRA[1,9 CD]PYRAZOL 6(2H) ONE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MAMMALIAN TARGET OF RAPAMYCIN; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; PENTOXIFYLLINE; PROPENTOFYLLINE; S6 KINASE; STRESS ACTIVATED PROTEIN KINASE; TUMOR NECROSIS FACTOR;

ANIMAL CELL; ARTICLE; ASTROCYTE; CELL CULTURE; CELL PROLIFERATION; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; SIGNAL TRANSDUCTION;

ANIMALS; ASTROCYTES; CELL PROLIFERATION; CELLS, CULTURED; CYCLIC AMP; ENZYME INHIBITORS; MALE; MITOGEN-ACTIVATED PROTEIN KINASES; NERVE TISSUE PROTEINS; NEUROPROTECTIVE AGENTS; PENTOXIFYLLINE; RATS; RATS, SPRAGUE-DAWLEY; SIGNAL TRANSDUCTION; SIROLIMUS; SPINAL CORD; TIME FACTORS; TUMOR NECROSIS FACTOR-ALPHA; XANTHINES;

EID: 84870907093     PISSN: 03604012     EISSN: 10974547     Source Type: Journal    
DOI: 10.1002/jnr.23144     Document Type: Article

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