Two-compartment tumor metabolism: Autophagy in the tumor microenvironment, and oxidative mitochondrial metabolism (OXPHOS) in cancer cells

Cell Cycle

Volumn 11, Issue 13, 2012, Pages 2545-2559

  Salem, Ahmed F ^a,b,c   Whitaker Menezes, Diana ^a,b   Lin, Zhao ^a,b   Martinez Outschoorn, Ubaldo E ^a,b   Tanowitz, Herbert B ^d   Al Zoubi, Mazhar Salim ^a,b   Howell, Anthony ^e   Pestell, Richard G ^a,b   Sotgia, Federica ^a,b,e   Lisanti, Michael P ^a,b,e  

^a THOMAS JEFFERSON UNIVERSITY   (United States)

^b THOMAS JEFFERSON UNIVERSITY   (United States)

^c NATIONAL ORGANIZATION FOR DRUG CONTROL AND RESEARCH NODCAR   (Egypt)

^d ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

^e UNIVERSITY OF MANCHESTER   (United Kingdom)

Author keywords

AMP kinase (AMPK); Autophagy; Cancer metabolism; Cancer associated fibroblasts; DNA damage response; DRAM; Glycolysis; GOLPH3; LKB1; Oxidative mitochondrial metabolism (OXPHOS); Tumor stroma

Indexed keywords

ADENYLATE KINASE; LACTIC ACID; PROTEIN KINASE LKB1;

ARTICLE; AUTOPHAGY; BIOGENESIS; BREAST CANCER; CANCER CELL; CONTROLLED STUDY; DAMAGE REGULATED AUTOPHAGY MODULATOR GENE; DISORDERS OF MITOCHONDRIAL FUNCTIONS; DNA DAMAGE; DNA REPAIR; ENZYME ACTIVATION; FIBROBLAST; GENE OVEREXPRESSION; GOLPH3 GENE; HUMAN; HUMAN CELL; KETOGENESIS; MITOCHONDRIAL ENERGY TRANSFER; MITOCHONDRIAL GENE; MITOCHONDRIAL RESPIRATION; TUMOR GROWTH; TUMOR MICROENVIRONMENT;

EID: 84863789652     PISSN: 15384101     EISSN: 15514005     Source Type: Journal    
DOI: 10.4161/cc.20920     Document Type: Article

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