-
1
-
-
15944389028
-
Simple coumarins and analogues in medicinal chemistry: Occurrence, synthesis and biological activity
-
Borges F, et al,. Simple coumarins and analogues in medicinal chemistry: occurrence, synthesis and biological activity. Curr Med Chem 2005; 12: 887-916.
-
(2005)
Curr Med Chem
, vol.12
, pp. 887-916
-
-
Borges, F.1
-
2
-
-
84857297856
-
Simple coumarins: Privileged scaffolds in medicinal chemistry
-
Borges F, et al,. Simple coumarins: privileged scaffolds in medicinal chemistry. Front Med Chem 2009; 4: 23-85.
-
(2009)
Front Med Chem
, vol.4
, pp. 23-85
-
-
Borges, F.1
-
3
-
-
33845933196
-
Inhibition of horseradish peroxidase catalytic activity by new 3-phenylcoumarin derivatives: Synthesis and structure-activity relationships
-
Kabeya L, et al,. Inhibition of horseradish peroxidase catalytic activity by new 3-phenylcoumarin derivatives: synthesis and structure-activity relationships. Bioorg Med Chem 2007; 15: 1516-1524.
-
(2007)
Bioorg Med Chem
, vol.15
, pp. 1516-1524
-
-
Kabeya, L.1
-
4
-
-
77953134777
-
Design, synthesis and anticancer activities of stilbene-coumarin hybrid compounds: Identification of novel proapoptotic agents
-
Belluti F, et al,. Design, synthesis and anticancer activities of stilbene-coumarin hybrid compounds: identification of novel proapoptotic agents. Bioorg Med Chem 2010; 18: 3543-3550.
-
(2010)
Bioorg Med Chem
, vol.18
, pp. 3543-3550
-
-
Belluti, F.1
-
5
-
-
77954313236
-
A novel synthesis of 3-aryl coumarins and evaluation of their antioxidant and lipoxygenase inhibitory activity
-
Roussaki M, et al,. A novel synthesis of 3-aryl coumarins and evaluation of their antioxidant and lipoxygenase inhibitory activity. Bioorg Med Chem Lett 2010; 20: 3889-3892.
-
(2010)
Bioorg Med Chem Lett
, vol.20
, pp. 3889-3892
-
-
Roussaki, M.1
-
6
-
-
34948830988
-
Discovery of novel DNA gyrase inhibitors by high-throughput virtual screening
-
Ostrov DA, et al,. Discovery of novel DNA gyrase inhibitors by high-throughput virtual screening. Antimicrob Agents Chemother 2007; 51: 3688-3698.
-
(2007)
Antimicrob Agents Chemother
, vol.51
, pp. 3688-3698
-
-
Ostrov, D.A.1
-
7
-
-
64349103355
-
Structure-activity relationship of new anti-hepatitis C virus agents: Heterobicycle-coumarin conjugates
-
Neyts J, et al,. Structure-activity relationship of new anti-hepatitis C virus agents: heterobicycle-coumarin conjugates. J Med Chem 2009; 52: 1486-1490.
-
(2009)
J Med Chem
, vol.52
, pp. 1486-1490
-
-
Neyts, J.1
-
8
-
-
33745941187
-
Coumarins as inhibitors of HIV reverse transcriptase
-
Kostova I,. Coumarins as inhibitors of HIV reverse transcriptase. Curr HIV Res 2006; 4: 347-363.
-
(2006)
Curr HIV Res
, vol.4
, pp. 347-363
-
-
Kostova, I.1
-
9
-
-
2442507656
-
Antibacterial chalcones - Bioisosteric replacement of the 4'-hydroxy group
-
Nielsen SF, et al,. Antibacterial chalcones-bioisosteric replacement of the 4'-hydroxy group. Bioorg Med Chem 2004; 12: 3047-3054.
-
(2004)
Bioorg Med Chem
, vol.12
, pp. 3047-3054
-
-
Nielsen, S.F.1
-
10
-
-
71049173711
-
Discovery of a novel class of potent coumarin monoamine oxidase B inhibitors: Development and biopharmacological profiling of 7-[(3-chlorobenzyl) oxy]-4-[(methylamino)-methyl]-2H-chromen-2-one methanesulfonate (NW-1772) as a highly potent, selective, reversible, and orally active monoamine oxidase B inhibitor
-
Pisani L, et al,. Discovery of a novel class of potent coumarin monoamine oxidase B inhibitors: development and biopharmacological profiling of 7-[(3-chlorobenzyl)oxy]-4-[(methylamino)-methyl]-2H-chromen-2-one methanesulfonate (NW-1772) as a highly potent, selective, reversible, and orally active monoamine oxidase B inhibitor. J Med Chem 2009; 52: 6685-6706.
-
(2009)
J Med Chem
, vol.52
, pp. 6685-6706
-
-
Pisani, L.1
-
11
-
-
65749116833
-
A new series of 3-phenylcoumarins as potent and selective MAO-B inhibitors
-
Matos MJ, et al,. A new series of 3-phenylcoumarins as potent and selective MAO-B inhibitors. Bioorg Med Chem Lett 2009; 19: 3268-3270.
-
(2009)
Bioorg Med Chem Lett
, vol.19
, pp. 3268-3270
-
-
Matos, M.J.1
-
12
-
-
68349155549
-
Synthesis and evaluation of 6-methyl-3-phenylcoumarins as potent and selective MAO-B inhibitors
-
Matos MJ, et al,. Synthesis and evaluation of 6-methyl-3-phenylcoumarins as potent and selective MAO-B inhibitors. Bioorg Med Chem Lett 2009; 19: 5053-5055.
-
(2009)
Bioorg Med Chem Lett
, vol.19
, pp. 5053-5055
-
-
Matos, M.J.1
-
13
-
-
77955715784
-
Halogenated 3-phenylcoumarins as potent and selective MAO-B inhibitors
-
Matos MJ, et al,. Halogenated 3-phenylcoumarins as potent and selective MAO-B inhibitors. Bioorg Med Chem Lett 2010; 20: 5157-5160.
-
(2010)
Bioorg Med Chem Lett
, vol.20
, pp. 5157-5160
-
-
Matos, M.J.1
-
14
-
-
80054908624
-
Synthesis and study of a series of 3-arylcoumarins as potent and selective monoamine oxidase B inhibitors
-
Matos MJ, et al,. Synthesis and study of a series of 3-arylcoumarins as potent and selective monoamine oxidase B inhibitors. J Med Chem 2011; 54: 7127-7137.
-
(2011)
J Med Chem
, vol.54
, pp. 7127-7137
-
-
Matos, M.J.1
-
15
-
-
79956100956
-
New halogenated phenylcoumarins as tyrosinase inhibitors
-
Matos MJ, et al,. New halogenated phenylcoumarins as tyrosinase inhibitors. Bioorg Med Chem Lett 2011; 21: 3342-3345.
-
(2011)
Bioorg Med Chem Lett
, vol.21
, pp. 3342-3345
-
-
Matos, M.J.1
-
16
-
-
84857253918
-
3-Substituted coumarins as dual inhibitors of AChE and MAO for the treatment of Alzheimer's disease
-
Viña D, et al,. 3-Substituted coumarins as dual inhibitors of AChE and MAO for the treatment of Alzheimer's disease. MedChemComm 2011; 3: 213-218.
-
(2011)
MedChemComm
, vol.3
, pp. 213-218
-
-
Viña, D.1
-
17
-
-
84655170309
-
Hydroxycoumarins as selective MAO-B inhibitors
-
Serra S, et al,. Hydroxycoumarins as selective MAO-B inhibitors. Bioorg Med Chem Lett 2012; 22: 258-261.
-
(2012)
Bioorg Med Chem Lett
, vol.22
, pp. 258-261
-
-
Serra, S.1
-
18
-
-
64549137053
-
Synthesis, molecular modeling, and selective inhibitory activity against human monoamine oxidases of 3-carboxamido-7-substituted coumarins
-
Chimenti F, et al,. Synthesis, molecular modeling, and selective inhibitory activity against human monoamine oxidases of 3-carboxamido-7- substituted coumarins. J Med Chem 2009; 52: 1935-1942.
-
(2009)
J Med Chem
, vol.52
, pp. 1935-1942
-
-
Chimenti, F.1
-
19
-
-
0035209620
-
International Union of Pharmacology. XXV. Nomenclature and classification of adenosine receptors
-
Fredholm BB, et al,. International Union of Pharmacology. XXV. Nomenclature and classification of adenosine receptors. Pharm Rev 2001; 53: 527-552.
-
(2001)
Pharm Rev
, vol.53
, pp. 527-552
-
-
Fredholm, B.B.1
-
21
-
-
0034052190
-
A(3) adenosine receptor ligands: History and perspectives
-
Baraldi PG, et al,. A(3) adenosine receptor ligands: history and perspectives. Med Res Rev 2000; 20: 103-128.
-
(2000)
Med Res Rev
, vol.20
, pp. 103-128
-
-
Baraldi, P.G.1
-
22
-
-
53849085809
-
Adenosine receptors and asthma in humans
-
Wilson CN,. Adenosine receptors and asthma in humans. Br J Pharmacol 2008; 155: 475-486.
-
(2008)
Br J Pharmacol
, vol.155
, pp. 475-486
-
-
Wilson, C.N.1
-
23
-
-
38749132550
-
Adenosine receptor antagonists: Translating medicinal chemistry and pharmacology into clinical utility
-
Baraldi PG, et al,. Adenosine receptor antagonists: translating medicinal chemistry and pharmacology into clinical utility. Chem Rev 2008; 108: 238-263.
-
(2008)
Chem Rev
, vol.108
, pp. 238-263
-
-
Baraldi, P.G.1
-
24
-
-
64549143749
-
Novel 2- and 4-substituted 1H-imidazo[4,5-c]quinolin-4-amine derivatives as allosteric modulators of the A3 adenosine receptor
-
Kim Y, et al,. Novel 2- and 4-substituted 1H-imidazo[4,5-c]quinolin-4- amine derivatives as allosteric modulators of the A3 adenosine receptor. J Med Chem 2009; 52: 2098-2108.
-
(2009)
J Med Chem
, vol.52
, pp. 2098-2108
-
-
Kim, Y.1
-
25
-
-
79960579532
-
Synthesis of a new series of 1H-imidazol-1-yl substituted 8-phenylxanthines as adenosine receptor ligands
-
Bansal R, et al,. Synthesis of a new series of 1H-imidazol-1-yl substituted 8-phenylxanthines as adenosine receptor ligands. Chem Biol 2011; 8: 1290-1300.
-
(2011)
Chem Biol
, vol.8
, pp. 1290-1300
-
-
Bansal, R.1
-
26
-
-
80054972494
-
Affinity prediction on A3 adenosine receptor antagonists: The chemometric approach
-
Luan F, et al,. Affinity prediction on A3 adenosine receptor antagonists: the chemometric approach. Bioorg Med Chem 2011; 19: 6853-6859.
-
(2011)
Bioorg Med Chem
, vol.19
, pp. 6853-6859
-
-
Luan, F.1
-
27
-
-
36549081419
-
The A3 adenosine receptor: An enigmatic player in cell biology
-
Gessi S, et al,. The A3 adenosine receptor: an enigmatic player in cell biology. Pharmacol Ther 2008; 117: 123-140.
-
(2008)
Pharmacol Ther
, vol.117
, pp. 123-140
-
-
Gessi, S.1
-
28
-
-
23744481524
-
1 cell cycle arrest and apoptosis in human promyelocytic leukemia HL-60 cells
-
1 cell cycle arrest and apoptosis in human promyelocytic leukemia HL-60 cells. Biochem Pharmacol 2005; 70: 918-924.
-
(2005)
Biochem Pharmacol
, vol.70
, pp. 918-924
-
-
Lee, E.J.1
-
29
-
-
0030433659
-
In vivo role of the adenosine A3 receptor: N6-2-(4-aminophenyl) ethyladenosine induces bronchospasm in BDE rats by a neurally mediated mechanism involving cells resembling mast cells
-
Meade CJ, et al,. In vivo role of the adenosine A3 receptor: N6-2-(4-aminophenyl)ethyladenosine induces bronchospasm in BDE rats by a neurally mediated mechanism involving cells resembling mast cells. J Pharmacol Exp Ther 1996; 279: 1148-1156.
-
(1996)
J Pharmacol Exp Ther
, vol.279
, pp. 1148-1156
-
-
Meade, C.J.1
-
30
-
-
84860664996
-
3 adenosine receptor ligands based on chromone scaffold
-
3 adenosine receptor ligands based on chromone scaffold. Biochem Pharmacol 2012; 84: 21-29.
-
(2012)
Biochem Pharmacol
, vol.84
, pp. 21-29
-
-
Gaspar, A.1
-
31
-
-
80054893720
-
3 da adenosina: Uma nova abordagem terapêutica no ĉncer
-
3 da adenosina: uma nova abordagem terapêutica no ĉncer. Quim Nova 2011; 34: 1417-1424.
-
(2011)
Quim Nova
, vol.34
, pp. 1417-1424
-
-
Gaspar, A.1
-
32
-
-
84870870078
-
Cumarindiol und Cumarin-Chromon-Tautomerie (Coumarindiol and coumarin-chromone tautomerism)
-
Fritz A, et al,. Cumarindiol und Cumarin-Chromon-Tautomerie (Coumarindiol and coumarin-chromone tautomerism). Chem Ber 1951; 84: 319-329.
-
(1951)
Chem Ber
, vol.84
, pp. 319-329
-
-
Fritz, A.1
-
33
-
-
0042586289
-
2,2-Dimethylchromene dimer. 2,2-Dimethylchromene and related compounds
-
Barnes CS, et al,. 2,2-Dimethylchromene dimer. 2,2-Dimethylchromene and related compounds. Tetrahedron 1963; 19: 839-847.
-
(1963)
Tetrahedron
, vol.19
, pp. 839-847
-
-
Barnes, C.S.1
-
34
-
-
3242775328
-
Reaction of two oxazolo[4',5': 3,4]coumarins with alkali
-
Stammer CH,. Reaction of two oxazolo[4',5': 3,4]coumarins with alkali. J Org Chem 1960; 25: 460-461.
-
(1960)
J Org Chem
, vol.25
, pp. 460-461
-
-
Stammer, C.H.1
-
35
-
-
84857307624
-
Some aminocoumarin derivatives possessing local anesthetic activity
-
Merchant JR, Martyres G,. Some aminocoumarin derivatives possessing local anesthetic activity. Curr Sci 1981; 50: 410-411.
-
(1981)
Curr Sci
, vol.50
, pp. 410-411
-
-
Merchant, J.R.1
Martyres, G.2
-
36
-
-
0031931065
-
Comparative pharmacology of human adenosine receptor subtypes - Characterization of stably transfected receptors in CHO cells
-
Klotz KN, et al,. Comparative pharmacology of human adenosine receptor subtypes-characterization of stably transfected receptors in CHO cells. Naunyn Schmiedebergs Arch Pharmacol 1997; 357: 1-9.
-
(1997)
Naunyn Schmiedebergs Arch Pharmacol
, vol.357
, pp. 1-9
-
-
Klotz, K.N.1
-
37
-
-
33846116634
-
[3H]HEMADO-a novel tritiated agonist selective for the human adenosine A3 receptor
-
Klotz KN, et al,. [3H]HEMADO-a novel tritiated agonist selective for the human adenosine A3 receptor. Eur J Pharmacol 2007; 556: 14-18.
-
(2007)
Eur J Pharmacol
, vol.556
, pp. 14-18
-
-
Klotz, K.N.1
-
38
-
-
0020084268
-
Validation and statistical analysis of a computer modeling method for quantitative analysis of radioligand binding data for mixtures of pharmacological receptor subtypes
-
De Lean A, et al,. Validation and statistical analysis of a computer modeling method for quantitative analysis of radioligand binding data for mixtures of pharmacological receptor subtypes. Mol Pharmacol 1982; 21: 5-16.
-
(1982)
Mol Pharmacol
, vol.21
, pp. 5-16
-
-
De Lean, A.1
|