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Bioorganic and Medicinal Chemistry Letters

Volumn 22, Issue 1, 2012, Pages 258-261

Hydroxycoumarins as selective MAO-B inhibitors

(9) Serra, Silvia a Ferino, Giulio a Matos, Maria João b Vázquez Rodríguez, Saleta b Delogu, Giovanna a Viña, Dolores b Cadoni, Enzo a Santana, Lourdes b Uriarte, Eugenio b

a UNIVERSITY OF CAGLIARI (Italy)

b UNIVERSITY OF SANTIAGO DE COMPOSTELA (Spain)

Author keywords

4 Hydroxycoumarin; Docking experiments; MAO inhibitory activity; Suzuki reaction

Indexed keywords

3 ARYL 4 HYDROXYCOUMARIN DERIVATIVE; AMINE OXIDASE (FLAVIN CONTAINING) ISOENZYME B; COUMARIN DERIVATIVE; IPRONIAZID; METHYL GROUP; MONOAMINE OXIDASE B INHIBITOR; PHENYL GROUP; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DRUG POTENTIATION; DRUG SELECTIVITY; DRUG SYNTHESIS; ENZYME INHIBITION; INHIBITION KINETICS; MOLECULAR DOCKING; NONHUMAN; STRUCTURE ACTIVITY RELATION; SUBSTITUTION LINE;

4-HYDROXYCOUMARINS; ANIMALS; AZIDES; BINDING SITES; CHEMISTRY, PHARMACEUTICAL; COMPUTER SIMULATION; DRUG DESIGN; HUMANS; INHIBITORY CONCENTRATION 50; MAGNETIC RESONANCE SPECTROSCOPY; MODELS, CHEMICAL; MONOAMINE OXIDASE; MONOAMINE OXIDASE INHIBITORS; STATIC ELECTRICITY; STRUCTURE-ACTIVITY RELATIONSHIP; THERMODYNAMICS;

EID: 84655170309 PISSN: 0960894X EISSN: 14643405 Source Type: Journal
DOI: 10.1016/j.bmcl.2011.11.020 Document Type: Article

Times cited : (55)

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