메뉴 건너뛰기




Volumn 155, Issue 4, 2008, Pages 475-486

Adenosine receptors and asthma in humans

Author keywords

A 1 AR; A 2a AR; A 2b AR; A 3 AR; Adenosine; ARs; Asthma

Indexed keywords

2 [4 (2 CARBOXYETHYL)PHENETHYLAMINO]ADENOSINE 5' (N ETHYLCARBOXAMIDE); 3 [4 (2,3,6,7 TETRAHYDRO 2,6 DIOXO 1,3 DIPROPYL 1H PURIN 8 YL)BICYCLO[2.2.2]OCTAN 1 YL]PROPIONIC ACID; 4 [3 [6 AMINO 9 (5 ETHYLCARBAMOYL 3,4 DIHYDROXYTETRAHYDRO 2 FURYL) 9H PURIN 2 YL] 2 PROPYNYL]CYCLOHEXANECARBOXYLIC ACID METHYL ESTER; 6 N (3 IODOBENZYL)ADENOSINE 5' N METHYLCARBOXAMIDE; 8 (2 NOR 1 ADAMANTYL) 1,3 DIPROPYLXANTHINE; ADENOSINE A1 RECEPTOR; ADENOSINE A2A RECEPTOR; ADENOSINE A2A RECEPTOR AGONIST; ADENOSINE A2B RECEPTOR; ADENOSINE A3 RECEPTOR; ADENOSINE A3 RECEPTOR ANTAGONIST; ADENOSINE RECEPTOR; ATL 313; CF 102; CVT 6883; EPI 2010; FLUTICASONE; G PROTEIN COUPLED RECEPTOR; GW 328267X; INTERLEUKIN 6; L 97 1; MRE 0094; MRS 1706; QAF 805; SLV 320; UK 432097; UNCLASSIFIED DRUG;

EID: 53849085809     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1038/bjp.2008.361     Document Type: Review
Times cited : (48)

References (101)
  • 1
    • 0023604895 scopus 로고
    • Selective activity of bamiphylline on adenosine A1 - receptors in rat brain
    • Abbrachio MP, Cattabeni F (1987). Selective activity of bamiphylline on adenosine A1 - receptors in rat brain. Pharmacol Res 19: 537-545.
    • (1987) Pharmacol Res , vol.19 , pp. 537-545
    • Abbrachio, M.P.1    Cattabeni, F.2
  • 3
    • 0028179236 scopus 로고
    • A single species of A1 adenosine receptor expressed in chinese hamster ovary cells not only inhibits cAMP accumulation but also stimulates phospholipase C and arachidonate release
    • Akbar M, Okajima F, Tomura H, Shimegi S, Kondo Y (1994). A single species of A1 adenosine receptor expressed in chinese hamster ovary cells not only inhibits cAMP accumulation but also stimulates phospholipase C and arachidonate release. Molecular Pharmacol 45: 1036-1042.
    • (1994) Molecular Pharmacol , vol.45 , pp. 1036-1042
    • Akbar, M.1    Okajima, F.2    Tomura, H.3    Shimegi, S.4    Kondo, Y.5
  • 6
    • 0037445151 scopus 로고    scopus 로고
    • Theophylline: New Perspectives for an old drug
    • Barnes PJ (2003). Theophylline: New Perspectives for an old drug. Am J Resp Crit Care Med 167: 813-818.
    • (2003) Am J Resp Crit Care Med , vol.167 , pp. 813-818
    • Barnes, P.J.1
  • 7
    • 0029821607 scopus 로고    scopus 로고
    • Realizing the potential of adenosine-receptor-based therapeutics
    • Barrett RJ (1996). Realizing the potential of adenosine-receptor-based therapeutics. Proc West Pharmacol Soc 39: 61-66.
    • (1996) Proc West Pharmacol Soc , vol.39 , pp. 61-66
    • Barrett, R.J.1
  • 8
    • 2542455596 scopus 로고    scopus 로고
    • Medication non-adherence and asthma treatment cost
    • Bender BG, Rand C (2004). Medication non-adherence and asthma treatment cost. Curr Opin Allergy Clin Immunol 4: 191-195.
    • (2004) Curr Opin Allergy Clin Immunol , vol.4 , pp. 191-195
    • Bender, B.G.1    Rand, C.2
  • 9
    • 0029932943 scopus 로고    scopus 로고
    • Selective attenuation by N-0861 (N6-Endonorboran-2-yl-9-methyladenine) of cardiac A1 adenosine receptormediated effects in humans
    • Bertolet BD, Belardinelli L, Franco EA, Nichols WW, Kerensky RA, Hill JA (1996). Selective attenuation by N-0861 (N6-Endonorboran-2-yl-9-methyladenine) of cardiac A1 adenosine receptormediated effects in humans. Circulation 93: 1871-1876.
    • (1996) Circulation , vol.93 , pp. 1871-1876
    • Bertolet, B.D.1    Belardinelli, L.2    Franco, E.A.3    Nichols, W.W.4    Kerensky, R.A.5    Hill, J.A.6
  • 10
    • 0026795551 scopus 로고
    • Isolated bronchi from asthmatics are hyper responsive to adenosine, which apparently acts indirectly by liberation of leukotrienes and histamine
    • Bjorck T, Gustafsson LE, Dahlen S-E (1992). Isolated bronchi from asthmatics are hyper responsive to adenosine, which apparently acts indirectly by liberation of leukotrienes and histamine. Am Rev Respir Dis 145: 1087-1091.
    • (1992) Am Rev Respir Dis , vol.145 , pp. 1087-1091
    • Bjorck, T.1    Gustafsson, L.E.2    Dahlen, S.-E.3
  • 11
    • 35348892756 scopus 로고    scopus 로고
    • In vivo adenosine A(2B) receptor desensitization in guinea-pig airway smooth muscle: Implications for asthma
    • Breschi MC, Blandizzi C, Fogli S, Martinelli C, Adinolfi B, Calderone V et al. (2007). In vivo adenosine A(2B) receptor desensitization in guinea-pig airway smooth muscle: implications for asthma. Eur J Pharmacol 575: 149-157.
    • (2007) Eur J Pharmacol , vol.575 , pp. 149-157
    • Breschi, M.C.1    Blandizzi, C.2    Fogli, S.3    Martinelli, C.4    Adinolfi, B.5    Calderone, V.6
  • 13
    • 0023685717 scopus 로고
    • Evaluation of the risk/benefit ratio of bamiphylline in the treatment of chronic obstructive lung disease
    • Catena E, Gunella G, Monici PPA, Oliani C (1988). Evaluation of the risk/benefit ratio of bamiphylline in the treatment of chronic obstructive lung disease. Italian J Chest Dis 42: 419-426.
    • (1988) Italian J Chest Dis , vol.42 , pp. 419-426
    • Catena, E.1    Gunella, G.2    Monici, P.P.A.3    Oliani, C.4
  • 14
    • 0030041938 scopus 로고    scopus 로고
    • Adenosine deaminase affects ligand-induced signalling by interacting with cell surface adenosine receptors
    • Ciruela F, Saura C, Canela EI, Mallol J, Lluis C, Franco R (1996). Adenosine deaminase affects ligand-induced signalling by interacting with cell surface adenosine receptors. FEBS Lett 380: 219-223.
    • (1996) FEBS Lett , vol.380 , pp. 219-223
    • Ciruela, F.1    Saura, C.2    Canela, E.I.3    Mallol, J.4    Lluis, C.5    Franco, R.6
  • 15
    • 0033019713 scopus 로고    scopus 로고
    • Adenosine and its nucleotides activate wild-type and R117H CFTR through an A2B receptor-coupled pathway
    • Clancy JP, Ruiz FE, Sorscher EJ (1999). Adenosine and its nucleotides activate wild-type and R117H CFTR through an A2B receptor-coupled pathway. Am J Physiol 276 (2 Pt. 1): C361-C369.
    • (1999) Am J Physiol , vol.276 , Issue.2 PART. 1
    • Clancy, J.P.1    Ruiz, F.E.2    Sorscher, E.J.3
  • 16
    • 36348967128 scopus 로고    scopus 로고
    • A1 adenosine receptor activation promotes angiogenesis and release of VEGF from monocytes
    • Clark AN, Youkey R, Liu X, Jia L, Blatt R, Day YJ et al. (2007). A1 adenosine receptor activation promotes angiogenesis and release of VEGF from monocytes. Circ Res 101: 1130-1138.
    • (2007) Circ Res , vol.101 , pp. 1130-1138
    • Clark, A.N.1    Youkey, R.2    Liu, X.3    Jia, L.4    Blatt, R.5    Day, Y.J.6
  • 17
    • 2542486456 scopus 로고    scopus 로고
    • Asthma: Mechanisms of disease persistence and progression
    • Cohn L, Elias JA, Chupp GL (2004). Asthma: mechanisms of disease persistence and progression. Annu Rev Immunol 22: 789-815.
    • (2004) Annu Rev Immunol , vol.22 , pp. 789-815
    • Cohn, L.1    Elias, J.A.2    Chupp, G.L.3
  • 18
    • 0025736793 scopus 로고
    • Theophylline inhibits early and late asthmatic reactions induced by allergens in asthmatic subjects
    • Crescioli S, Spinazzi A, Plebani M, Pozzani M, Mapp CE, Boschetto P et al. (1991). Theophylline inhibits early and late asthmatic reactions induced by allergens in asthmatic subjects. Ann Allergy 66: 245-251.
    • (1991) Ann Allergy , vol.66 , pp. 245-251
    • Crescioli, S.1    Spinazzi, A.2    Plebani, M.3    Pozzani, M.4    Mapp, C.E.5    Boschetto, P.6
  • 19
    • 33747657023 scopus 로고    scopus 로고
    • Adenosine receptors and wound healing, revised
    • Cronstein BN (2006). Adenosine receptors and wound healing, revised. Scientific World J 6: 984-991.
    • (2006) Scientific World J , vol.6 , pp. 984-991
    • Cronstein, B.N.1
  • 20
    • 0025349998 scopus 로고
    • The adenosine/neutrophil paradox resolved: Human neutrophils possess both A1 and A2 receptors that promote chemotaxis and inhibit O2 generation, respectively
    • Cronstein BN, Daguma L, Nichols D, Hutchison AJ, Williams M (1990). The adenosine/neutrophil paradox resolved: human neutrophils possess both A1 and A2 receptors that promote chemotaxis and inhibit O2 generation, respectively. J Clin Invest 85: 1150-1157.
    • (1990) J Clin Invest , vol.85 , pp. 1150-1157
    • Cronstein, B.N.1    Daguma, L.2    Nichols, D.3    Hutchison, A.J.4    Williams, M.5
  • 21
    • 0026507232 scopus 로고
    • Neutrophil adherence to endothelium is enhanced via adenosine A1 receptors and inhibited via adenosine A2 receptors
    • Cronstein BN, Levin RI, Phillips M, Hirschhorn R, Abramson SB, Weissman G (1992). Neutrophil adherence to endothelium is enhanced via adenosine A1 receptors and inhibited via adenosine A2 receptors. J Immunol 148: 2201-2206.
    • (1992) J Immunol , vol.148 , pp. 2201-2206
    • Cronstein, B.N.1    Levin, R.I.2    Phillips, M.3    Hirschhorn, R.4    Abramson, S.B.5    Weissman, G.6
  • 22
    • 0020655642 scopus 로고
    • Inhaled adenosine and guanosine on airway resistance in normal and asthmatic subjects
    • Cushley MJ, Tattersfield AE, Holgate ST (1983). Inhaled adenosine and guanosine on airway resistance in normal and asthmatic subjects. Br J Clin Pharmacol 15: 161-165.
    • (1983) Br J Clin Pharmacol , vol.15 , pp. 161-165
    • Cushley, M.J.1    Tattersfield, A.E.2    Holgate, S.T.3
  • 23
    • 0000966697 scopus 로고
    • Allergen challenge of lung tissue from asthmatics elicits bronchial contraction that correlates with the release of leukotrienes C4, D4, and E4
    • Dahlen S-E, Hansson G, Hedqvist P, Bjorck T, Granstrom E, Dahlen B (1983). Allergen challenge of lung tissue from asthmatics elicits bronchial contraction that correlates with the release of leukotrienes C4, D4, and E4. Proc Natl Acad Sci USA 80: 1712-1716.
    • (1983) Proc Natl Acad Sci USA , vol.80 , pp. 1712-1716
    • Dahlen, S.-E.1    Hansson, G.2    Hedqvist, P.3    Bjorck, T.4    Granstrom, E.5    Dahlen, B.6
  • 24
    • 0036468658 scopus 로고    scopus 로고
    • Bronchial responsiveness to adenosine 5′-monophosphate (AMP) and methacholine differ in their relationship with airway allergy and baseline FEV1
    • de Meer G, Heederik D, Postma DS (2002). Bronchial responsiveness to adenosine 5′-monophosphate (AMP) and methacholine differ in their relationship with airway allergy and baseline FEV1. Am J Respir Crit Care Med 165: 327-331.
    • (2002) Am J Respir Crit Care Med , vol.165 , pp. 327-331
    • de Meer, G.1    Heederik, D.2    Postma, D.S.3
  • 25
    • 34848887450 scopus 로고    scopus 로고
    • The effect of KW-3902, an adenosine A1 receptor antagonist, on renal function and renal plasma flow in ambulatory patients with heart failure and renal impairment
    • Dittrich HC, Gupta DK, Hack TC, Dowling T, Callahan J, Thomson S (2007). The effect of KW-3902, an adenosine A1 receptor antagonist, on renal function and renal plasma flow in ambulatory patients with heart failure and renal impairment. J Card Failure 13: 609-617.
    • (2007) J Card Failure , vol.13 , pp. 609-617
    • Dittrich, H.C.1    Gupta, D.K.2    Hack, T.C.3    Dowling, T.4    Callahan, J.5    Thomson, S.6
  • 28
    • 33749162650 scopus 로고    scopus 로고
    • Adenosine A1 receptors mediate mobilization of calcium in human bronchial smooth muscle cells
    • Ethier MF, Madison JM (2006). Adenosine A1 receptors mediate mobilization of calcium in human bronchial smooth muscle cells. Am J Respir Cell Mol Biol 35: 496-502.
    • (2006) Am J Respir Cell Mol Biol , vol.35 , pp. 496-502
    • Ethier, M.F.1    Madison, J.M.2
  • 29
    • 0028972108 scopus 로고
    • Adenosine A2b receptors evoke interleukin-8 secretion in human mast cells: An enprofylline-sensitive mechanism with implications for asthma
    • Feoktistov I, Biaggioni I (1995). Adenosine A2b receptors evoke interleukin-8 secretion in human mast cells: an enprofylline-sensitive mechanism with implications for asthma. J Clin Invest 96: 1979-1986.
    • (1995) J Clin Invest , vol.96 , pp. 1979-1986
    • Feoktistov, I.1    Biaggioni, I.2
  • 30
    • 0037155773 scopus 로고    scopus 로고
    • Differential expression of adenosine receptors in human endothelial cells: Role of A2b receptors in angiogenic factor regulation
    • Feoktistov I, Goldstein AE, Ryzhov S, Zeng D, Belardinelli L, Maa T et al. (2002). Differential expression of adenosine receptors in human endothelial cells: role of A2b receptors in angiogenic factor regulation. Circ Res 90: 531-538.
    • (2002) Circ Res , vol.90 , pp. 531-538
    • Feoktistov, I.1    Goldstein, A.E.2    Ryzhov, S.3    Zeng, D.4    Belardinelli, L.5    Maa, T.6
  • 31
    • 0038604758 scopus 로고    scopus 로고
    • Pharmacology and therapeutic applications of A3 receptor subtype
    • Fishman P, Bar-Yehuda S (2003). Pharmacology and therapeutic applications of A3 receptor subtype. Curr Topics Med Chem 3: 463-469.
    • (2003) Curr Topics Med Chem , vol.3 , pp. 463-469
    • Fishman, P.1    Bar-Yehuda, S.2
  • 32
    • 0032901246 scopus 로고    scopus 로고
    • Adenosine induces histamine release from human bronchoalveolar lavage mast cells
    • Forsythe P, McGarvey LPA, Heaney LG, MacMahon J, Ennis M (1999). Adenosine induces histamine release from human bronchoalveolar lavage mast cells. Clin Sci 96: 349-355.
    • (1999) Clin Sci , vol.96 , pp. 349-355
    • Forsythe, P.1    McGarvey, L.P.A.2    Heaney, L.G.3    MacMahon, J.4    Ennis, M.5
  • 33
    • 0021071418 scopus 로고
    • Pharmacokinetic study of bamiphylline (and metabolites) in healthy volunteers using chromatography and mass spectrometry
    • Foutillan JP, Lefebvre MA, Ingrand I (1983). Pharmacokinetic study of bamiphylline (and metabolites) in healthy volunteers using chromatography and mass spectrometry. Therapie 38: 647-658.
    • (1983) Therapie , vol.38 , pp. 647-658
    • Foutillan, J.P.1    Lefebvre, M.A.2    Ingrand, I.3
  • 34
    • 0037040392 scopus 로고    scopus 로고
    • Effects of CGS 21680, a selective adenosine A2A receptor agonist, on allergic airways inflammation in the rat
    • Fozard JR, Ellis KM, Villela Dantas MF, Tigani B, Mazzoni L (2002). Effects of CGS 21680, a selective adenosine A2A receptor agonist, on allergic airways inflammation in the rat. Eur J Pharmacol 438: 183-188.
    • (2002) Eur J Pharmacol , vol.438 , pp. 183-188
    • Fozard, J.R.1    Ellis, K.M.2    Villela Dantas, M.F.3    Tigani, B.4    Mazzoni, L.5
  • 35
    • 0141616552 scopus 로고    scopus 로고
    • Adenosine receptors as targets for drug development
    • Fredholm BB (2003). Adenosine receptors as targets for drug development. Drug News Perspect 16: 283-289.
    • (2003) Drug News Perspect , vol.16 , pp. 283-289
    • Fredholm, B.B.1
  • 36
    • 0035209620 scopus 로고    scopus 로고
    • International union of pharmacology. XXV. Nomenclature and classification of adenosine receptors
    • Fredholm BB, Ijzerman AP, Jacobson KA, Klotz K-N, Linden J (2001). International union of pharmacology. XXV. Nomenclature and classification of adenosine receptors. Pharmacol Rev 53: 527-552.
    • (2001) Pharmacol Rev , vol.53 , pp. 527-552
    • Fredholm, B.B.1    Ijzerman, A.P.2    Jacobson, K.A.3    Klotz, K.-N.4    Linden, J.5
  • 37
    • 0027267757 scopus 로고
    • Bamiphylline improves exercise-induced myocardial ischemia through a novel mechanism of action
    • Gaspardone A, Crea F, Iamele M, Tomai F, Versaci F, Pellegrino A et al. (1993). Bamiphylline improves exercise-induced myocardial ischemia through a novel mechanism of action. Circulation 88: 502-508.
    • (1993) Circulation , vol.88 , pp. 502-508
    • Gaspardone, A.1    Crea, F.2    Iamele, M.3    Tomai, F.4    Versaci, F.5    Pellegrino, A.6
  • 40
    • 34848892574 scopus 로고    scopus 로고
    • The effect of KW-3902, an adenosine A1-receptor antagonist, on diuresis and renal function in patients with acute decompensated heart failure and renal impairment or diuretic resistance
    • Givertz MM, Massie BM, Fields TK, Pearson LL, Dittrich HC (2007). The effect of KW-3902, an adenosine A1-receptor antagonist, on diuresis and renal function in patients with acute decompensated heart failure and renal impairment or diuretic resistance. J Am Coll Cardiol 50: 1551-1560.
    • (2007) J Am Coll Cardiol , vol.50 , pp. 1551-1560
    • Givertz, M.M.1    Massie, B.M.2    Fields, T.K.3    Pearson, L.L.4    Dittrich, H.C.5
  • 41
    • 0037133628 scopus 로고    scopus 로고
    • BG9719 (CVT-124), an A1 adenosine receptor antagonist, protects against the decline in renal function observed with diuretic therapy
    • Gottlieb SS, Brater C, Thomas I, Havranek E, Bourge R, Goldman S et al. (2002). BG9719 (CVT-124), an A1 adenosine receptor antagonist, protects against the decline in renal function observed with diuretic therapy. Circulation 105: 1348-1353.
    • (2002) Circulation , vol.105 , pp. 1348-1353
    • Gottlieb, S.S.1    Brater, C.2    Thomas, I.3    Havranek, E.4    Bourge, R.5    Goldman, S.6
  • 42
    • 34547608258 scopus 로고    scopus 로고
    • Effects of multiple oral doses of an A1 adenosine receptor antagonist, BG 9928, in patients with heart failure
    • Greenberg B, Ignatius T, Banish D, Goldman S, Havranek E, Massie BM et al. (2007). Effects of multiple oral doses of an A1 adenosine receptor antagonist, BG 9928, in patients with heart failure. J Am Coll Cardiol 50: 600-606.
    • (2007) J Am Coll Cardiol , vol.50 , pp. 600-606
    • Greenberg, B.1    Ignatius, T.2    Banish, D.3    Goldman, S.4    Havranek, E.5    Massie, B.M.6
  • 43
    • 0348222661 scopus 로고    scopus 로고
    • Adenosine: An endogenous regulator of innate immunity
    • Hasko G, Cronstein BN (2004). Adenosine: an endogenous regulator of innate immunity. Trends in Immunol 25: 33-39.
    • (2004) Trends in Immunol , vol.25 , pp. 33-39
    • Hasko, G.1    Cronstein, B.N.2
  • 44
    • 0036468722 scopus 로고    scopus 로고
    • Adenosine provocation: A new test for allergic type airway inflammation
    • Holgate ST (2002). Adenosine provocation: a new test for allergic type airway inflammation. Am J Respir Crit Care Med 165: 317-319.
    • (2002) Am J Respir Crit Care Med , vol.165 , pp. 317-319
    • Holgate, S.T.1
  • 45
    • 0035923676 scopus 로고    scopus 로고
    • Compartmentalized autocrine signaling to cystic fibrosis transmembrane conductance regulator at the apical membrane of airway epithelial cells
    • Huang P, Lazarowski ER, Tarran R, Milgram SL, Boucher RC, Stutts MJ (2001). Compartmentalized autocrine signaling to cystic fibrosis transmembrane conductance regulator at the apical membrane of airway epithelial cells. Proc Natl Acad Sci USA 98: 14120-14125.
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 14120-14125
    • Huang, P.1    Lazarowski, E.R.2    Tarran, R.3    Milgram, S.L.4    Boucher, R.C.5    Stutts, M.J.6
  • 46
    • 0036902490 scopus 로고    scopus 로고
    • Adenosine in exhaled breath condensate in healthy volunteers and in patients with asthma
    • Huszar E, Vass G, Vizi E, Csoma Z, Barat E, Molnar VG et al. (2002). Adenosine in exhaled breath condensate in healthy volunteers and in patients with asthma. Eur Respir J 20: 1393-1398.
    • (2002) Eur Respir J , vol.20 , pp. 1393-1398
    • Huszar, E.1    Vass, G.2    Vizi, E.3    Csoma, Z.4    Barat, E.5    Molnar, V.G.6
  • 48
  • 49
  • 50
    • 33745044738 scopus 로고    scopus 로고
    • Adenosine A2b receptor (A2bR) signals through adenylate cyclase (AC) 6 isoform in the intestinal epithelial cells
    • Kolachala VL, Obertone TS, Wang L, Merlin D, Sitaraman SV (2006). Adenosine A2b receptor (A2bR) signals through adenylate cyclase (AC) 6 isoform in the intestinal epithelial cells. Biochim Biophys Acta 1760: 1102-1108.
    • (2006) Biochim Biophys Acta , vol.1760 , pp. 1102-1108
    • Kolachala, V.L.1    Obertone, T.S.2    Wang, L.3    Merlin, D.4    Sitaraman, S.V.5
  • 51
    • 23644458915 scopus 로고    scopus 로고
    • Increase of adenosine A1 receptor gene expression in cerebral ischemia of Wistar rats
    • Lai D-M, Tu Y-K, Liu I-M, Cheng J-T (2005). Increase of adenosine A1 receptor gene expression in cerebral ischemia of Wistar rats. Neurosci Lett 387: 59-61.
    • (2005) Neurosci Lett , vol.387 , pp. 59-61
    • Lai, D.-M.1    Tu, Y.-K.2    Liu, I.-M.3    Cheng, J.-T.4
  • 52
    • 53849089167 scopus 로고    scopus 로고
    • Efficacy of EPI-2010 (An inhaled respirable anti-sense oligonucleotide: RASON) in moderate/severe persistent asthma
    • Langley SJ, Allen DJ, Houghton C, Woodcock A (2005). Efficacy of EPI-2010 (An inhaled respirable anti-sense oligonucleotide: RASON) in moderate/severe persistent asthma. Am J Resp Crit Care Med 171: A360.
    • (2005) Am J Resp Crit Care Med , vol.171
    • Langley, S.J.1    Allen, D.J.2    Houghton, C.3    Woodcock, A.4
  • 53
    • 0032547817 scopus 로고    scopus 로고
    • Neutrophil-derived 5′-adenosine monophosphate promotes endothelial barrier function via CD73-mediated conversion to adenosine and endothelial A2B receptor activation
    • Lennon PF, Taylor CT, Stahl GL, Colgan SP (1998). Neutrophil-derived 5′-adenosine monophosphate promotes endothelial barrier function via CD73-mediated conversion to adenosine and endothelial A2B receptor activation. J Exp Med 188: 1433-1443.
    • (1998) J Exp Med , vol.188 , pp. 1433-1443
    • Lennon, P.F.1    Taylor, C.T.2    Stahl, G.L.3    Colgan, S.P.4
  • 54
    • 2442449306 scopus 로고    scopus 로고
    • Adenosine, inflammation, and asthma-a review
    • Livingston M, Heaney LG, Ennis M (2004). Adenosine, inflammation, and asthma-a review. Inflamm Res 53: 171-178.
    • (2004) Inflamm Res , vol.53 , pp. 171-178
    • Livingston, M.1    Heaney, L.G.2    Ennis, M.3
  • 55
    • 36649008545 scopus 로고    scopus 로고
    • Effect of an inhaled adenosine A2A agonist on the allergen-induced late asthmatic response
    • Luijk B, van den Berge M, Kerstjens HAM, Postma DS, Cass L, Sabin A et al. (2008). Effect of an inhaled adenosine A2A agonist on the allergen-induced late asthmatic response. Allergy 63: 75-80.
    • (2008) Allergy , vol.63 , pp. 75-80
    • Luijk, B.1    van den Berge, M.2    Kerstjens, H.A.M.3    Postma, D.S.4    Cass, L.5    Sabin, A.6
  • 56
    • 0027015559 scopus 로고
    • Adenosine receptors on human leukocytes. IV. Characterization of an A1/Ri receptor
    • Marone G, Petracca R, Vigorita S, Genovese A, Casolaro V (1992). Adenosine receptors on human leukocytes. IV. Characterization of an A1/Ri receptor. Int J Clin Lab Res 22: 235-242.
    • (1992) Int J Clin Lab Res , vol.22 , pp. 235-242
    • Marone, G.1    Petracca, R.2    Vigorita, S.3    Genovese, A.4    Casolaro, V.5
  • 57
    • 0002580093 scopus 로고    scopus 로고
    • Adenosine
    • Barnes PJ, Grunstein MM, Leff AR, Woolcock AJ eds, Lippincott-Raven Publishers: Philadelphia, PA. pp
    • Marquardt DL (1997). Adenosine. In: Barnes PJ, Grunstein MM, Leff AR, Woolcock AJ (eds). Asthma. Lippincott-Raven Publishers: Philadelphia, PA. pp 585-591.
    • (1997) Asthma , pp. 585-591
    • Marquardt, D.L.1
  • 58
    • 2342590065 scopus 로고    scopus 로고
    • Masoli M, Fabian D, Holt S, Beasley R, for the Global Initiative for Asthma (GINA) Program (2004). The global burden of asthma: executive summary of the GINA dissemination committee report. Allergy 59: 469-478.
    • Masoli M, Fabian D, Holt S, Beasley R, for the Global Initiative for Asthma (GINA) Program (2004). The global burden of asthma: executive summary of the GINA dissemination committee report. Allergy 59: 469-478.
  • 60
    • 2442689337 scopus 로고    scopus 로고
    • Adenosine A(2A) receptor activation promotes wound neovascularization by stimulating angiogenesis and vasculogenesis
    • Montesinos MC, Shaw JP, Yee H, Shamamian P, Cronstein BN (2006). Adenosine A(2A) receptor activation promotes wound neovascularization by stimulating angiogenesis and vasculogenesis. Am J Pathol 164: 1887-1892.
    • (2006) Am J Pathol , vol.164 , pp. 1887-1892
    • Montesinos, M.C.1    Shaw, J.P.2    Yee, H.3    Shamamian, P.4    Cronstein, B.N.5
  • 61
    • 0030698058 scopus 로고    scopus 로고
    • Wound healing is accelerated by agonists of adenosine A2 (Gs-linked) receptors
    • Montesinos MC, Gadangi P, Longaker M, Sung J, Levine J, Nilsen D et al. (1997). Wound healing is accelerated by agonists of adenosine A2 (Gs-linked) receptors. J Exp Med 186: 1615-1620.
    • (1997) J Exp Med , vol.186 , pp. 1615-1620
    • Montesinos, M.C.1    Gadangi, P.2    Longaker, M.3    Sung, J.4    Levine, J.5    Nilsen, D.6
  • 62
    • 25644432618 scopus 로고
    • Multicentre trial on the efficacy and tolerability of bamiphylline in the treatment of patients with COLD
    • Morandini G (1988). Multicentre trial on the efficacy and tolerability of bamiphylline in the treatment of patients with COLD. La Presse Medicale 3: 1-10.
    • (1988) La Presse Medicale , vol.3 , pp. 1-10
    • Morandini, G.1
  • 64
    • 33847159974 scopus 로고    scopus 로고
    • Effect of a specific and selective A(2B) adenosine receptor antagonist on adenosine agonist AMP and allergen-induced airway responsiveness and cellular influx in a mouse model of asthma
    • Mustafa SJ, Nadeem A, Fan M, Zhong H, Belardinelli L, Zeng D (2007). Effect of a specific and selective A(2B) adenosine receptor antagonist on adenosine agonist AMP and allergen-induced airway responsiveness and cellular influx in a mouse model of asthma. J Pharmacol Exp Ther 320: 1246-1251.
    • (2007) J Pharmacol Exp Ther , vol.320 , pp. 1246-1251
    • Mustafa, S.J.1    Nadeem, A.2    Fan, M.3    Zhong, H.4    Belardinelli, L.5    Zeng, D.6
  • 66
    • 33750464221 scopus 로고    scopus 로고
    • Adenosine A1 receptor antagonist versus montelukast on airway reactivity and inflammation
    • Nadeem A, Obiefuna PC, Wilson CN, Mustafa SJ (2006). Adenosine A1 receptor antagonist versus montelukast on airway reactivity and inflammation. E J Pharmacol 551: 116-124.
    • (2006) E J Pharmacol , vol.551 , pp. 116-124
    • Nadeem, A.1    Obiefuna, P.C.2    Wilson, C.N.3    Mustafa, S.J.4
  • 68
    • 25644440742 scopus 로고    scopus 로고
    • A Novel A1 Adenosine Receptor Antagonist, L-97-1, [3-[2-(4-Aminophenyl)-ethyl]- 8-benzyl-7-{2-[ethyl-(2-hydroxy-ethyl)-amino]-ethyl}-1-propyl-3, 7-dihydro-purine-2,6-dione], Reduces Allergic Responses to House Dust Mite in an Allergic Rabbit Model of Asthma
    • Obiefuna PC, Batra VK, Nadeem A, Borron P, Wilson CN, Mustafa SJ (2005). A Novel A1 Adenosine Receptor Antagonist, L-97-1, [3-[2-(4-Aminophenyl)-ethyl]- 8-benzyl-7-{2-[ethyl-(2-hydroxy-ethyl)-amino]-ethyl}-1-propyl-3, 7-dihydro-purine-2,6-dione], Reduces Allergic Responses to House Dust Mite in an Allergic Rabbit Model of Asthma. J Pharmacol Exp Ther 315: 329-336.
    • (2005) J Pharmacol Exp Ther , vol.315 , pp. 329-336
    • Obiefuna, P.C.1    Batra, V.K.2    Nadeem, A.3    Borron, P.4    Wilson, C.N.5    Mustafa, S.J.6
  • 70
    • 0033971607 scopus 로고    scopus 로고
    • The role of receptor structure in determining adenosine receptor activity
    • Olah ME, Stiles GL (2000). The role of receptor structure in determining adenosine receptor activity. Pharmacol Ther 85: 55-75.
    • (2000) Pharmacol Ther , vol.85 , pp. 55-75
    • Olah, M.E.1    Stiles, G.L.2
  • 72
    • 53849142430 scopus 로고    scopus 로고
    • QAF805, an A2b/A3 adenosine receptor antagonist does not attenuate AMP challenge in subjects with asthma
    • Pascoe SJ, Knight H, Woessner R (2007). QAF805, an A2b/A3 adenosine receptor antagonist does not attenuate AMP challenge in subjects with asthma. Am J Resp Crit Care Med 175: A682.
    • (2007) Am J Resp Crit Care Med , vol.175
    • Pascoe, S.J.1    Knight, H.2    Woessner, R.3
  • 74
    • 0035989842 scopus 로고    scopus 로고
    • Adenosine-receptor subtypes: Their relevance to adenosine-mediated responses in asthma and chronic obstructed pulmonary disease
    • Polosa R (2002). Adenosine-receptor subtypes: their relevance to adenosine-mediated responses in asthma and chronic obstructed pulmonary disease. Eur Respir J 20: 488-496.
    • (2002) Eur Respir J , vol.20 , pp. 488-496
    • Polosa, R.1
  • 75
    • 33747031382 scopus 로고    scopus 로고
    • Adenosine is upregulated during peritonitis and is involved in downregulation of inflammation
    • Rogachev B, Ziv NY, Mazar J, Nakav S, Chaimovitz C, Zlotnik M et al. (2006). Adenosine is upregulated during peritonitis and is involved in downregulation of inflammation. Kidney Internal 70: 675-681.
    • (2006) Kidney Internal , vol.70 , pp. 675-681
    • Rogachev, B.1    Ziv, N.Y.2    Mazar, J.3    Nakav, S.4    Chaimovitz, C.5    Zlotnik, M.6
  • 77
    • 0038057340 scopus 로고    scopus 로고
    • Targeting adenosine receptors: Novel therapeutic targets in asthma and chronic obstructive pulmonary disease
    • Rorke S, Holgate ST (2002). Targeting adenosine receptors: novel therapeutic targets in asthma and chronic obstructive pulmonary disease. Am J Respir Med 1: 99-105.
    • (2002) Am J Respir Med , vol.1 , pp. 99-105
    • Rorke, S.1    Holgate, S.T.2
  • 78
    • 33645034489 scopus 로고    scopus 로고
    • Adenosine receptors: Promising targets for the development of novel therapeutics and diagnostics for asthma
    • Russo C, Arcidiacono G, Polosa R (2006). Adenosine receptors: promising targets for the development of novel therapeutics and diagnostics for asthma. Fund Clin Pharmacol 20: 9-19.
    • (2006) Fund Clin Pharmacol , vol.20 , pp. 9-19
    • Russo, C.1    Arcidiacono, G.2    Polosa, R.3
  • 79
    • 2942560494 scopus 로고    scopus 로고
    • Adenosine-activated mast cells induce IgE synthesis by B lymphocytes: An A2B-mediated process involving Th2 cytokines IL-4 and IL-13 with implications for asthma
    • Ryzhov S, Goldstein AE, Matafonov A, Zeng D, Biaggioni I, Feoktistov I (2004). Adenosine-activated mast cells induce IgE synthesis by B lymphocytes: an A2B-mediated process involving Th2 cytokines IL-4 and IL-13 with implications for asthma. J Immunol 172: 7726-7733.
    • (2004) J Immunol , vol.172 , pp. 7726-7733
    • Ryzhov, S.1    Goldstein, A.E.2    Matafonov, A.3    Zeng, D.4    Biaggioni, I.5    Feoktistov, I.6
  • 81
    • 0027320145 scopus 로고
    • Human mononuclear phagocytes express adenosine A1 receptors. A novel mechanism for differential regulation of Fc gamma receptor function
    • Salmon JE, Brogle N, Brownlie C, Edberg JC, Kimberly RP, Chen BX et al. (1993). Human mononuclear phagocytes express adenosine A1 receptors. A novel mechanism for differential regulation of Fc gamma receptor function. J Immunol 151: 2775-2785.
    • (1993) J Immunol , vol.151 , pp. 2775-2785
    • Salmon, J.E.1    Brogle, N.2    Brownlie, C.3    Edberg, J.C.4    Kimberly, R.P.5    Chen, B.X.6
  • 82
    • 0025135242 scopus 로고
    • Fc gamma receptor-mediated functions in neutrophils are modulated by adenosine receptor occupancy. A1 receptors are stimulatory and A2 receptors are inhibitory
    • Salmon JE, Cronstein BN (1990). Fc gamma receptor-mediated functions in neutrophils are modulated by adenosine receptor occupancy. A1 receptors are stimulatory and A2 receptors are inhibitory. J Immunol 145: 2235-2240.
    • (1990) J Immunol , vol.145 , pp. 2235-2240
    • Salmon, J.E.1    Cronstein, B.N.2
  • 83
    • 2942744546 scopus 로고    scopus 로고
    • Cardiovascular effects of beta-agonists in patients with asthma and COPD: A metanalysis
    • Salpeter SR, Ormiston TM, Salpeter EE (2004). Cardiovascular effects of beta-agonists in patients with asthma and COPD: a metanalysis. Chest 125: 2309-2321.
    • (2004) Chest , vol.125 , pp. 2309-2321
    • Salpeter, S.R.1    Ormiston, T.M.2    Salpeter, E.E.3
  • 84
    • 0029892284 scopus 로고    scopus 로고
    • Adenosine deaminase interacts with A1 adenosine receptors in pig brain cortical membranes
    • Saura C, Ciruela F, Casadó V, Canela EI, Mallol J, Lluis C et al. (1996). Adenosine deaminase interacts with A1 adenosine receptors in pig brain cortical membranes. J Neurochem 66: 1675-1682.
    • (1996) J Neurochem , vol.66 , pp. 1675-1682
    • Saura, C.1    Ciruela, F.2    Casadó, V.3    Canela, E.I.4    Mallol, J.5    Lluis, C.6
  • 85
    • 3242719685 scopus 로고    scopus 로고
    • Asthma as a risk factor for COPD in a longitudinal study
    • Silva GE, Sherrill DL, Guerra S, Barbee RA (2004). Asthma as a risk factor for COPD in a longitudinal study. Chest 126: 59-65.
    • (2004) Chest , vol.126 , pp. 59-65
    • Silva, G.E.1    Sherrill, D.L.2    Guerra, S.3    Barbee, R.A.4
  • 86
    • 3142655932 scopus 로고    scopus 로고
    • Pharmacological management to reduce exacerbations in adults with asthma
    • Sin DD, Man J, Sharpe H, Gan WQ, Man SFP (2004). Pharmacological management to reduce exacerbations in adults with asthma. JAMA 292: 367-376.
    • (2004) JAMA , vol.292 , pp. 367-376
    • Sin, D.D.1    Man, J.2    Sharpe, H.3    Gan, W.Q.4    Man, S.F.P.5
  • 87
    • 0043162106 scopus 로고    scopus 로고
    • Research applications and implications of adenosine in diseased airways
    • Spicuzza L, Bonfiglio C, Polosa R (2003). Research applications and implications of adenosine in diseased airways. Trends in Pharmacol Sciences 24: 409-413.
    • (2003) Trends in Pharmacol Sciences , vol.24 , pp. 409-413
    • Spicuzza, L.1    Bonfiglio, C.2    Polosa, R.3
  • 88
    • 0035542639 scopus 로고    scopus 로고
    • A3 receptors mediate rapid inflammatory cell influx into the lungs of sensitized guinea-pigs
    • Spruntulis LM, Broadley KJ (2001). A3 receptors mediate rapid inflammatory cell influx into the lungs of sensitized guinea-pigs. Clin Exp Allergy 31: 943-951.
    • (2001) Clin Exp Allergy , vol.31 , pp. 943-951
    • Spruntulis, L.M.1    Broadley, K.J.2
  • 89
    • 0028985715 scopus 로고
    • The A2b adenosine receptor mediates cAMP responses to adenosine receptor agonists in human intestinal epithelia
    • Strohmeier GR, Reppert SM, Lencer WI, Madara JL (1995). The A2b adenosine receptor mediates cAMP responses to adenosine receptor agonists in human intestinal epithelia. J Biol Chem 270: 2387-2394.
    • (1995) J Biol Chem , vol.270 , pp. 2387-2394
    • Strohmeier, G.R.1    Reppert, S.M.2    Lencer, W.I.3    Madara, J.L.4
  • 90
    • 0347093665 scopus 로고    scopus 로고
    • Adenosine A2A receptor agonists as antiinflammatory agents
    • Sullivan GW (2003). Adenosine A2A receptor agonists as antiinflammatory agents. Curr Opin Investig Drugs 4: 1313-1319.
    • (2003) Curr Opin Investig Drugs , vol.4 , pp. 1313-1319
    • Sullivan, G.W.1
  • 92
    • 33746666617 scopus 로고    scopus 로고
    • Role of A2B adenosine receptor signaling in adenosine-dependent pulmonary inflammation and injury
    • Sun C-X, Zhong H, Mohsenin A, Morschl E, Chunn JL, Molina JG et al. (2006). Role of A2B adenosine receptor signaling in adenosine-dependent pulmonary inflammation and injury. J Clin Invest 116: 2173-2182.
    • (2006) J Clin Invest , vol.116 , pp. 2173-2182
    • Sun, C.-X.1    Zhong, H.2    Mohsenin, A.3    Morschl, E.4    Chunn, J.L.5    Molina, J.G.6
  • 94
    • 6344278503 scopus 로고    scopus 로고
    • Tolerability, pharmacokinetics and concentration- dependent hemodynamic effects of oral CF 101, an A3 adenosine receptor agonist, in healthy young men
    • van Troostenburg A-R, Clark EV, Carey WDH, Warrington SJ, Kerns WD, Cohn I et al. (2004). Tolerability, pharmacokinetics and concentration- dependent hemodynamic effects of oral CF 101, an A3 adenosine receptor agonist, in healthy young men. Internat J Clin Pharmacol Ther 42: 534-542.
    • (2004) Internat J Clin Pharmacol Ther , vol.42 , pp. 534-542
    • van Troostenburg, A.-R.1    Clark, E.V.2    Carey, W.D.H.3    Warrington, S.J.4    Kerns, W.D.5    Cohn, I.6
  • 95
    • 0036130498 scopus 로고    scopus 로고
    • Plasma adenosine concentration increases during exercise: A possible contributing factor in exercise-induced bronchoconstriction in asthma
    • Vizi E, Huzzar E, Csoma Z, Boszormenyi-Nagy G, Barat E, Horvath I et al. (2002). Plasma adenosine concentration increases during exercise: a possible contributing factor in exercise-induced bronchoconstriction in asthma. J Allergy Clin Immunol 109: 446-448.
    • (2002) J Allergy Clin Immunol , vol.109 , pp. 446-448
    • Vizi, E.1    Huzzar, E.2    Csoma, Z.3    Boszormenyi-Nagy, G.4    Barat, E.5    Horvath, I.6
  • 96
    • 0027428723 scopus 로고
    • Development of tolerance to the antihypertensive effects of highly selective adenosine A2a agonists upon chronic administration
    • Webb RL, Sills MA, Chovan JP, Peppard JV, Francis JE (1993). Development of tolerance to the antihypertensive effects of highly selective adenosine A2a agonists upon chronic administration. J Pharmacol Exp Ther 267: 287-295.
    • (1993) J Pharmacol Exp Ther , vol.267 , pp. 287-295
    • Webb, R.L.1    Sills, M.A.2    Chovan, J.P.3    Peppard, J.V.4    Francis, J.E.5
  • 97
    • 0036374565 scopus 로고    scopus 로고
    • Lipopolysaccharide binds to and activates A1 adenosine receptors on human pulmonary artery endothelial cells
    • Wilson CN, Batra VK (2002). Lipopolysaccharide binds to and activates A1 adenosine receptors on human pulmonary artery endothelial cells. J Endotoxin Res 8: 263-271.
    • (2002) J Endotoxin Res , vol.8 , pp. 263-271
    • Wilson, C.N.1    Batra, V.K.2
  • 98
    • 33745817034 scopus 로고    scopus 로고
    • The A2B adenosine receptor protects against inflammation and excessive vascular adhesion
    • Yang D, Zhang Y, Nguyen HG, Koupenova M, Chauhan AK, Makitalo M et al. (2006). The A2B adenosine receptor protects against inflammation and excessive vascular adhesion. J Clin Invest 116: 1913-1923.
    • (2006) J Clin Invest , vol.116 , pp. 1913-1923
    • Yang, D.1    Zhang, Y.2    Nguyen, H.G.3    Koupenova, M.4    Chauhan, A.K.5    Makitalo, M.6
  • 100
    • 11144230939 scopus 로고    scopus 로고
    • Synergy between A2b adenosine receptors and hypoxia in activating human lung fibroblasts
    • Zhong H, Belardinelli L, Maa T, Zeng D (2005). Synergy between A2b adenosine receptors and hypoxia in activating human lung fibroblasts. Am J Respir Cell Mol Biol 32: 2-8.
    • (2005) Am J Respir Cell Mol Biol , vol.32 , pp. 2-8
    • Zhong, H.1    Belardinelli, L.2    Maa, T.3    Zeng, D.4
  • 101
    • 33750687938 scopus 로고    scopus 로고
    • A2B adenosine receptors induce IL-19 from bronchial epithelial cells, resulting in TNF-alpha increase
    • Zhong H, Wu Y, Belardinelli L, Zeng D (2006). A2B adenosine receptors induce IL-19 from bronchial epithelial cells, resulting in TNF-alpha increase. Am J Resp Cell Mol Biol 35: 587-592.
    • (2006) Am J Resp Cell Mol Biol , vol.35 , pp. 587-592
    • Zhong, H.1    Wu, Y.2    Belardinelli, L.3    Zeng, D.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.