Synthesis of a new series of 1H-imidazol-1-yl substituted 8-phenylxanthines as adenosine receptor ligands

Chemistry and Biodiversity

Volumn 8, Issue 7, 2011, Pages 1290-1300

  Bansal, Ranju ^a   Kumar, Gulshan ^a   Gandhi, Deepika ^a   Young, Louise C ^b   Harvey, Alan L ^b  

^a PANJAB UNIVERSITY   (India)

^b UNIVERSITY OF STRATHCLYDE   (United Kingdom)

Author keywords

Adenosine receptor ligands; Xanthines, 8 phenyl

Indexed keywords

3,7 DIHYDRO 8 [3 [3 (1H IMIDAZOL 1 YL)PROPOXY] 4 METHOXYPHENYL] 1,3 DIMETHYL 1H PURINE 2,6 DIONE; 3,7 DIHYDRO 8 [3 [3 (1H IMIDAZOL 1 YL)PROPOXY]PHENYL] 1,3 DIMETHYL 1H PURINE 2,6 DIONE; 3,7 DIHYDRO 8 [3 [3 (1H IMIDAZOL 1 YL)PROPOXY]PHENYL] 1,3 DIMETHYL 7 PROPYL 1H PURINE 2,6 DIONE; 3,7 DIHYDRO 8 [4 [2 (1H IMIDAZOL 1 YL)ETHOXY] 3 METHOXYPHENYL] 1,3 DIMETHYL 1H PURINE 2,6 DIONE; 3,7 DIHYDRO 8 [4 [3 (1H IMIDAZOL 1 YL)PROPOXY] 3 METHOXYPHENYL] 1,3 DIMETHYL 1H PURINE 2,6 DIONE; 3,7 DIHYDRO 8 [4 [3 (1H IMIDAZOL 1 YL)PROPOXY] 3 METHOXYPHENYL] 1,3 DIMETHYL 7 PROPYL 1H PURINE 2,6 DIONE; 3,7 DIHYDRO 8 [4 [3 (1H IMIDAZOL 1 YL)PROPOXY] 3 METHOXYPHENYL] 1,3,7 TRIMETHYL 1H PURINE 2,6 DIONE; 3,7 DIHYDRO 8 [4 [3 (1H IMIDAZOL 1 YL)PROPOXY] 3 METHOXYPHENYL] 3 METHYL 1 PROPYL 1H PURINE 2,6 DIONE; 3,7 DIHYDRO 8 [4 [3 (1H IMIDAZOL 1 YL)PROPOXY] 3 METHOXYPHENYL] 3 METHYL 1H PURINE 2,6 DIONE; 8 [3 (3 CHLOROPROPOXY) 4 METHOXYPHENYL] 3,7 DIHYDRO 1,3 DIMETHYL 1H PURINE 2,6 DIONE; 8 [3 (3 CHLOROPROPOXY)PHENYL] 1,3 DIMETHYL 3,7 DIHYDRO 1H PURINE 2,6 DIONE; 8 [3 (3 CHLOROPROPOXY)PHENYL] 3,7 DIHYDRO 1,3 DIMETHYL 7 PROPYL 1H PURINE 2,6 DIONE; 8 [4 (2 CHLOROETHOXY) 3 METHOXYPHENYL] 3,7 DIHYDRO 1,3 DIMETHYL 1H PURINE 2,6 DIONE; 8 [4 (3 CHLOROPROPOXY) 3 METHOXYPHENYL] 3,7 DIHYDRO 1,3 DIMETHYL 1H PURINE 2,6 DIONE; 8 [4 (3 CHLOROPROPOXY) 3 METHOXYPHENYL] 3,7 DIHYDRO 1,3 DIMETHYL 7 PROPYL 1H PURINE 2,6 DIONE; 8 [4 (3 CHLOROPROPOXY) 3 METHOXYPHENYL] 3,7 DIHYDRO 1,3,7 TRIMETHYL 1H PURINE 2,6 DIONE; 8 [4 (3 CHLOROPROPOXY) 3 METHOXYPHENYL] 3,7 DIHYDRO 3 METHYL 1 PROPYL 1H PURINE 2,6 DIONE; 8 [4 (3 CHLOROPROPOXY) 3 METHOXYPHENYL] 3,7 DIHYDRO 3 METHYL 1H PURINE 2,6 DIONE; 8 PHENYLXANTHINE DERIVATIVE; ADENOSINE A1 RECEPTOR; ADENOSINE A2A RECEPTOR; ADENOSINE RECEPTOR; IMIDAZOLE; RADIOLIGAND; UNCLASSIFIED DRUG; XANTHINE DERIVATIVE;

ARTICLE; BINDING AFFINITY; BIOLOGICAL ACTIVITY; DRUG BINDING; DRUG SYNTHESIS; IN VITRO STUDY;

HUMANS; IMIDAZOLES; LIGANDS; PROTEIN BINDING; RECEPTORS, PURINERGIC P1; XANTHINES;

EID: 79960579532     PISSN: 16121872     EISSN: 16121880     Source Type: Journal    
DOI: 10.1002/cbdv.201000141     Document Type: Article

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