-
1
-
-
34250877865
-
Genetic pathways to primary and secondary glioblastoma
-
DOI 10.2353/ajpath.2007.070011
-
Ohgaki H, Kleihues P. Genetic pathways to primary and secondary glioblastoma. Am J Pathol 2007;170:1445-53. (Pubitemid 47339290)
-
(2007)
American Journal of Pathology
, vol.170
, Issue.5
, pp. 1445-1453
-
-
Ohgaki, H.1
Kleihues, P.2
-
2
-
-
1842330265
-
Hemizygous or homozygous deletion of the chromosomal region containing the p16(INK4a) gene is associated with amplification of the EGF receptor gene in glioblastomas
-
DOI 10.1002/(SICI)1097-0215(19970926)73:1<57::AID-IJC10>3.0.CO;2-2
-
Hegi ME, zur Hausen A, Ruedi D, Malin G, Kleihues P. Hemizygous or homozygous deletion of the chromosomal region containing the p16INK4a gene is associated with amplification of the EGF receptor gene in glioblastomas. Int J Cancer 1997;73:57-63. (Pubitemid 27445991)
-
(1997)
International Journal of Cancer
, vol.73
, Issue.1
, pp. 57-63
-
-
Hegi, M.E.1
Zur, H.A.2
Ruedi, D.3
Malin, G.4
Kleihues, P.5
-
3
-
-
70849122697
-
Glioblastoma subclasses can be defined by activity among signal transduction pathways and associated genomic alterations
-
Brennan C, Momota H, Hambardzumyan D, Ozawa T, Tandon A, Pedraza A, et al. Glioblastoma subclasses can be defined by activity among signal transduction pathways and associated genomic alterations. PLoS One 2009;4:e7752.
-
(2009)
PLoS One
, vol.4
-
-
Brennan, C.1
Momota, H.2
Hambardzumyan, D.3
Ozawa, T.4
Tandon, A.5
Pedraza, A.6
-
4
-
-
0034722889
-
The EGF receptor family as targets for cancer therapy
-
DOI 10.1038/sj.onc.1204082
-
Mendelsohn J, Baselga J. The EGF receptor family as targets for cancer therapy. Oncogene 2000;19:6550-65. (Pubitemid 32197693)
-
(2000)
Oncogene
, vol.19
, Issue.56
, pp. 6550-6565
-
-
Mendelsohn, J.1
Baselga, J.2
-
5
-
-
2342471392
-
Activating Mutations in the Epidermal Growth Factor Receptor Underlying Responsiveness of Non-Small-Cell Lung Cancer to Gefitinib
-
DOI 10.1056/NEJMoa040938
-
Lynch TJ, Bell DW, Sordella R, Gurubhagavatula S, Okimoto RA, Brannigan BW, et al. Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to Gefitinib. N Engl J Med 2004;350:2129-39. (Pubitemid 38637993)
-
(2004)
New England Journal of Medicine
, vol.350
, Issue.21
, pp. 2129-2139
-
-
Lynch, T.J.1
Bell, D.W.2
Sordella, R.3
Gurubhagavatula, S.4
Okimoto, R.A.5
Brannigan, B.W.6
Harris, P.L.7
Haserlat, S.M.8
Supko, J.G.9
Haluska, F.G.10
Louis, D.N.11
Christiani, D.C.12
Settleman, J.13
Haber, D.A.14
-
6
-
-
2342624080
-
EGFR mutations in lung, cancer: Correlation with clinical response to gefitinib therapy
-
DOI 10.1126/science.1099314
-
Paez JG, Janne PA, Lee JC, Tracy S, Greulich H, Gabriel S, et al. EGFR mutations in lung cancer: correlation with clinical response to Gefitinib therapy. Science 2004;304:1497-500. (Pubitemid 38720929)
-
(2004)
Science
, vol.304
, Issue.5676
, pp. 1497-1500
-
-
Paez, J.G.1
Janne, P.A.2
Lee, J.C.3
Tracy, S.4
Greulich, H.5
Gabriel, S.6
Herman, P.7
Kaye, F.J.8
Lindeman, N.9
Boggon, T.J.10
Naoki, K.11
Sasaki, H.12
Fujii, Y.13
Eck, M.J.14
Sellers, W.R.15
Johnson, B.E.16
Meyerson, M.17
-
7
-
-
0034163550
-
Diversity and frequency of epidermal growth factor receptor mutations in human glioblastomas
-
Frederick L, Wang XY, Eley G, James CD. Diversity and frequency of epidermal growth factor receptor mutations in human glioblastomas. Cancer Res 2000;60:1383-7. (Pubitemid 30152011)
-
(2000)
Cancer Research
, vol.60
, Issue.5
, pp. 1383-1387
-
-
Frederick, L.1
Wang, X.-Y.2
Eley, G.3
James, C.D.4
-
8
-
-
33845926387
-
Epidermal growth factor receptor activation in glioblastoma through novel missense mutations in the extracellular domain
-
Lee JC, Vivanco I, Beroukhim R, Huang JH, Feng WL, Debiasi RM, et al. Epidermal growth factor receptor activation in glioblastoma through novel missense mutations in the extracellular domain. PLoS Med 2006;3:e485.
-
(2006)
PLoS Med
, vol.3
-
-
Lee, J.C.1
Vivanco, I.2
Beroukhim, R.3
Huang, J.H.4
Feng, W.L.5
Debiasi, R.M.6
-
9
-
-
0025790916
-
Genes for epidermal growth factor receptor, transforming growth factor a, and epidermal growth factor and their expression in human gliomas in vivo
-
Ekstrand AJ, James CD, Cavenee WK, Seliger B, Petterson RF, Collins VP. Genes for epidermal growth factor receptor, transforming growth factor a, and epidermal growth factor and their expression in human gliomas in vivo. Cancer Res 1991;51:2164-72.
-
(1991)
Cancer Res
, vol.51
, pp. 2164-2172
-
-
Ekstrand, A.J.1
James, C.D.2
Cavenee, W.K.3
Seliger, B.4
Petterson, R.F.5
Collins, V.P.6
-
10
-
-
0028146767
-
A mutant epidermal growth factor receptor common in human glioma confers enhanced tumorigenicity
-
DOI 10.1073/pnas.91.16.7727
-
Nishikawa R, Ji XD, Harmon RC, Lazar CS, Gill GN, Cavenee WK, et al. A mutant epidermal growth factor receptor common in human glioma confers enhanced tumorigenicity. Proc Natl Acad Sci U S A 1994;91:7727-31. (Pubitemid 24238258)
-
(1994)
Proceedings of the National Academy of Sciences of the United States of America
, vol.91
, Issue.16
, pp. 7727-7731
-
-
Nishikawa, R.1
Ji, X.-D.2
Harmon, R.C.3
Lazar, C.S.4
Gill, G.N.5
Cavenee, W.K.6
Huang, H.-J.S.7
-
11
-
-
1842500007
-
Phase II trial of gefitinib in recurrent glioblastoma
-
DOI 10.1200/JCO.2004.08.110
-
Rich JN, Reardon DA, Peery T, Dowell JM, Quinn JA, Penne KL, et al. Phase II trial of gefitinib in recurrent glioblastoma. J Clin Oncol 2004;22:133-42. (Pubitemid 41095125)
-
(2004)
Journal of Clinical Oncology
, vol.22
, Issue.1
, pp. 133-142
-
-
Rich, J.N.1
Reardon, D.A.2
Peery, T.3
Dowell, J.M.4
Quinn, J.A.5
Penne, K.L.6
Wikstrand, C.J.7
Van Duyn, L.B.8
Dancey, J.E.9
McLendon, R.E.10
Kao, J.C.11
Stenzel, T.T.12
Rasheed, B.K.A.13
Tourt-Uhlig, S.E.14
Herndon II, J.E.15
Vredenburgh, J.J.16
Sampson, J.H.17
Friedman, A.H.18
Bigner, D.D.19
Friedman, H.S.20
more..
-
12
-
-
62449150719
-
Randomized phase II trial of erlotinib versus temozolomide or carmustine in recurrent glioblastoma: EORTC brain tumor group study 26034
-
Van Den Bent MJ, Brandes AA, Rampling R, Kouwenhoven MC, Kros JM, Carpentier AF, et al. Randomized phase II trial of erlotinib versus temozolomide or carmustine in recurrent glioblastoma: EORTC brain tumor group study 26034. J Clin Oncol 2009;27:1268-74.
-
(2009)
J Clin Oncol
, vol.27
, pp. 1268-1274
-
-
Van Den Bent, M.J.1
Brandes, A.A.2
Rampling, R.3
Kouwenhoven, M.C.4
Kros, J.M.5
Carpentier, A.F.6
-
13
-
-
78049306732
-
Safety and efficacy of erlotinib in first-relapse glioblastoma: A phase II open-label study
-
Yung WK, Vredenburgh JJ, Cloughesy TF, Nghiemphu P, Klencke B, Gilbert MR, et al. Safety and efficacy of erlotinib in first-relapse glioblastoma: a phase II open-label study. Neuro Oncol 2010;12:1061-70.
-
(2010)
Neuro Oncol
, vol.12
, pp. 1061-1070
-
-
Yung, W.K.1
Vredenburgh, J.J.2
Cloughesy, T.F.3
Nghiemphu, P.4
Klencke, B.5
Gilbert, M.R.6
-
14
-
-
65949101643
-
Phase II trial of preirradiation and concurrent temozolomide in patients with newly diagnosed anaplastic oligodendrogliomas and mixed anaplastic oligoastrocytomas: RTOG BR0131
-
Vogelbaum MA, Berkey B, Peereboom D, Macdonald D, Giannini C, Suh JH, et al. Phase II trial of preirradiation and concurrent temozolomide in patients with newly diagnosed anaplastic oligodendrogliomas and mixed anaplastic oligoastrocytomas: RTOG BR0131. Neuro Oncol 2009;11:167-75.
-
(2009)
Neuro Oncol
, vol.11
, pp. 167-175
-
-
Vogelbaum, M.A.1
Berkey, B.2
Peereboom, D.3
Macdonald, D.4
Giannini, C.5
Suh, J.H.6
-
15
-
-
39749169093
-
Epidermal growth factor receptor inhibitors in neuro-oncology: Hopes and disappointments
-
DOI 10.1158/1078-0432.CCR-07-1810
-
Brandes AA, Franceschi E, Tosoni A, Hegi ME, Stupp R. Epidermal growth factor receptor inhibitors in neuro-oncology: hopes and disappointments. Clin Cancer Res 2008;14:957-60. (Pubitemid 351302539)
-
(2008)
Clinical Cancer Research
, vol.14
, Issue.4
, pp. 957-960
-
-
Brandes, A.A.1
Franceschi, E.2
Tosoni, A.3
Hegi, M.E.4
Stupp, R.5
-
16
-
-
34147184365
-
Identification of molecular characteristics correlated with glioblastoma sensitivity to EGFR kinase inhibition through use of an intracranial xenograft test panel
-
Sarkaria JN, Yang L, Grogan PT, Kitange GJ, Carlson BL, Schroeder MA, et al. Identification of molecular characteristics correlated with glioblastoma sensitivity to EGFR kinase inhibition through use of an intracranial xenograft test panel. Mol Cancer Ther 2007;6:1167-74.
-
(2007)
Mol Cancer Ther
, vol.6
, pp. 1167-1174
-
-
Sarkaria, J.N.1
Yang, L.2
Grogan, P.T.3
Kitange, G.J.4
Carlson, B.L.5
Schroeder, M.A.6
-
17
-
-
21444450373
-
Epidermal growth factor receptor, protein kinase B/Akt, and glioma response to erlotinib
-
DOI 10.1093/jnci/dji161
-
Haas-Kogan DA, Prados MD, Tihan T, Eberhard DA, Jelluma N, Arvold ND, et al. Epidermal growth factor receptor, protein kinase B/Akt, and glioma response to erlotinib. J Natl Cancer Inst 2005;97:880-7. (Pubitemid 41417939)
-
(2005)
Journal of the National Cancer Institute
, vol.97
, Issue.12
, pp. 880-887
-
-
Haas-Kogan, D.A.1
Prados, M.D.2
Tihan, T.3
Eberhard, D.A.4
Jelluma, N.5
Arvold, N.D.6
Baumber, R.7
Lamborn, K.R.8
Kapadia, A.9
Malec, M.10
Berger, M.S.11
Stokoe, D.12
-
18
-
-
27744606737
-
Molecular determinants of the response of glioblastomas to EGFR kinase inhibitors
-
DOI 10.1056/NEJMoa051918
-
Mellinghoff IK, Wang MY, Vivanco I, Haas-Kogan DA, Zhu S, Dia EQ, et al. Molecular determinants of the response of glioblastomas to EGFR kinase inhibitors. N Engl J Med 2005;353:2012-24. (Pubitemid 41609094)
-
(2005)
New England Journal of Medicine
, vol.353
, Issue.19
, pp. 2012-2024
-
-
Mellinghoff, I.K.1
Wang, M.Y.2
Vivanco, I.3
Haas-Kogan, D.A.4
Zhu, S.5
Dia, E.Q.6
Lu, K.V.7
Yoshimoto, K.8
Huang, J.H.Y.9
Chute, D.J.10
Riggs, B.L.11
Horvath, S.12
Liau, L.M.13
Cavenee, W.K.14
Nagesh, R.P.15
Beroukhim, R.16
Peck, T.C.17
Lee, J.C.18
Sellers, W.R.19
Stokoe, D.20
Prados, M.21
Cloughesy, T.F.22
Sawyers, C.L.23
Mischel, P.S.24
more..
-
19
-
-
22844447077
-
Specific method for determination of gefitinib in human plasma, mouse plasma and tissues using high performance liquid chromatography coupled to tandem mass spectrometry
-
DOI 10.1016/j.jchromb.2005.01.027
-
Zhao M, Hartke C, Jimeno A, Li J, He P, Zabelina Y, et al. Specific method for determination of gefitinib in human plasma, mouse plasma and tissues using high performance liquid chromatography coupled to tandem mass spectrometry. J Chromatogr B Anal Technol Biomed Life Sci 2005;819:73-80. (Pubitemid 41583164)
-
(2005)
Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences
, vol.819
, Issue.1
, pp. 73-80
-
-
Zhao, M.1
Hartke, C.2
Jimeno, A.3
Li, J.4
He, P.5
Zabelina, Y.6
Hidalgo, M.7
Baker, S.D.8
-
20
-
-
33947256848
-
Gefitinib concentrations in human glioblastoma tissue
-
DOI 10.1007/s11060-006-9257-3
-
Hofer S, Frei K. Gefitinib concentrations in human glioblastoma tissue. J Neurooncol 2007;82:175-6. (Pubitemid 46431861)
-
(2007)
Journal of Neuro-Oncology
, vol.82
, Issue.2
, pp. 175-176
-
-
Hofer, S.1
Frei, K.2
-
21
-
-
0035392952
-
Loss of focal adhesion kinase (FAK) inhibits epidermal growth factor receptor-dependent migration and induces aggregation of nh(2)-terminal FAK in the nuclei of apoptotic glioblastoma cells
-
Jones G, Machado J, Jr, Merlo A. Loss of focal adhesion kinase (FAK) inhibits epidermal growth factor receptor-dependent migration and induces aggregation of nh(2)-terminal FAK in the nuclei of apoptotic glioblastoma cells. Cancer Res 2001;61:4978-81.
-
(2001)
Cancer Res
, vol.61
, pp. 4978-4981
-
-
Jones, G.1
Machado Jr., J.2
Merlo, A.3
-
22
-
-
47649131468
-
6-methylguanine-DNA methyltransferase gene promoter methylation in glioma
-
DOI 10.2353/jmoldx.2008.070169
-
Vlassenbroeck I, Califice S, Diserens AC, Migliavacca E, Straub J, Di Stefano I, et al. Validation of real-time methylation-specific PCR to determine O6-methylguanine-DNA methyltransferase gene promoter methylation in glioma. J Mol Diagn 2008;10:332-7. (Pubitemid 352019119)
-
(2008)
Journal of Molecular Diagnostics
, vol.10
, Issue.4
, pp. 332-337
-
-
Vlassenbroeck, I.1
Califice, S.2
Diserens, A.-C.3
Migliavacca, E.4
Straub, J.5
Di, S.I.6
Moreau, F.7
Hamou, M.-F.8
Renard, I.9
Delorenzi, M.10
Flamion, B.11
DiGuiseppi, J.12
Bierau, K.13
Hegi, M.E.14
-
23
-
-
46449115281
-
Stem cell-related "self-renewal" signature and high epidermal growth factor receptor expression associated with resistance to concomitant chemoradiotherapy in glioblastoma
-
Murat A, Migliavacca E, Gorlia T, Lambiv WL, Shay T, Hamou MF, et al. Stem cell-related "self-renewal" signature and high epidermal growth factor receptor expression associated with resistance to concomitant chemoradiotherapy in glioblastoma. J Clin Oncol 2008;26:3015-24.
-
(2008)
J Clin Oncol
, vol.26
, pp. 3015-3024
-
-
Murat, A.1
Migliavacca, E.2
Gorlia, T.3
Lambiv, W.L.4
Shay, T.5
Hamou, M.F.6
-
24
-
-
67650085341
-
Validation of a phosphoprotein array assay for characterization of human tyrosine kinase receptor downstream signaling in breast cancer
-
Chergui F, Chretien A-S, Bouali S, Ramacci C, Rouyer M, Bastogne T, et al. Validation of a phosphoprotein array assay for characterization of human tyrosine kinase receptor downstream signaling in breast cancer. Clin Chem 2009;55:1327-36.
-
(2009)
Clin Chem
, vol.55
, pp. 1327-1336
-
-
Chergui, F.1
Chretien, A.-S.2
Bouali, S.3
Ramacci, C.4
Rouyer, M.5
Bastogne, T.6
-
25
-
-
0022268856
-
Exploring, confirming, and randomization tests
-
Romesburg HC. Exploring, confirming, and randomization tests. Comput Geosci 1985;11:19-37.
-
(1985)
Comput Geosci
, vol.11
, pp. 19-37
-
-
Romesburg, H.C.1
-
26
-
-
79951480123
-
-
R Development Core Team. Vienna, Austria: R Foundation for Statistical Computing
-
R Development Core Team. R: A language and environment for statistical computing. Vienna, Austria: R Foundation for Statistical Computing; 2010.
-
(2010)
R: A Language and Environment for Statistical Computing
-
-
-
28
-
-
18044389786
-
Tumor penetration of gefitinib (Iressa), an epidermal growth factor receptor tyrosine kinase inhibitor
-
DOI 10.1158/1535-7163.MCT-04-0329
-
McKillop D, Partridge EA, Kemp JV, Spence MP, Kendrew J, Barnett S, et al. Tumor penetration of gefitinib (Iressa), an epidermal growth factor receptor tyrosine kinase inhibitor. Mol Cancer Ther 2005;4:641-9. (Pubitemid 40601846)
-
(2005)
Molecular Cancer Therapeutics
, vol.4
, Issue.4
, pp. 641-649
-
-
McKillop, D.1
Partridge, E.A.2
Kemp, J.V.3
Spence, M.P.4
Kendrew, J.5
Barnett, S.6
Wood, P.G.7
Giles, P.B.8
Patterson, A.B.9
Bichat, F.10
Guilbaud, N.11
Stephens, T.C.12
-
29
-
-
38749125368
-
Pilot phase II study of preoperative gefitinib in early stage non-small cell lung cancer with assessment of intratumour gefitinib levels and tumour target modulation
-
abstract
-
Haura E, Somme E, Becker D, McKillop D, Bepler G. Pilot phase II study of preoperative gefitinib in early stage non-small cell lung cancer with assessment of intratumour gefitinib levels and tumour target modulation [abstract]. J Clin Oncol 2007;25:7603.
-
(2007)
J Clin Oncol
, vol.25
, pp. 7603
-
-
Haura, E.1
Somme, E.2
Becker, D.3
McKillop, D.4
Bepler, G.5
-
30
-
-
73349094018
-
Epidermal growth factor receptor tyrosine kinase inhibitors: Similar but different?
-
Rukazenkov Y, Speake G, Marshall G, Anderton J, Davies BR, Wilkinson RW, et al. Epidermal growth factor receptor tyrosine kinase inhibitors: similar but different? Anticancer Drugs 2009;20:856-66.
-
(2009)
Anticancer Drugs
, vol.20
, pp. 856-866
-
-
Rukazenkov, Y.1
Speake, G.2
Marshall, G.3
Anderton, J.4
Davies, B.R.5
Wilkinson, R.W.6
-
31
-
-
42649106522
-
Clinical features, mechanisms, and management of pseudoprogression in malignant gliomas
-
DOI 10.1016/S1470-2045(08)70125-6, PII S1470204508701256
-
Brandsma D, Stalpers L, Taal W, Sminia P, Van Den Bent MJ. Clinical features, mechanisms, and management of pseudoprogression in malignant gliomas. Lancet Oncol 2008;9:453-61. (Pubitemid 351597795)
-
(2008)
The Lancet Oncology
, vol.9
, Issue.5
, pp. 453-461
-
-
Brandsma, D.1
Stalpers, L.2
Taal, W.3
Sminia, P.4
Van Den, B.M.J.5
-
32
-
-
0026772431
-
Platelet-derived growth factor and its receptors in human glioma tissue: Expression of messenger RNA and protein suggests the presence of autocrine and paracrine loops
-
Hermanson M, Funa K, Hartman M, Claesson-Welsh L, Heldin C-H, Westermark B, et al. Platelet-derived growth factor and its receptors in human glioma tissue: expression of messenger RNA and protein suggests the presence of autocrine and paracrine loops. Cancer Res 1992;52:3213-9.
-
(1992)
Cancer Res
, vol.52
, pp. 3213-3219
-
-
Hermanson, M.1
Funa, K.2
Hartman, M.3
Claesson-Welsh, L.4
Heldin, C.-H.5
Westermark, B.6
-
33
-
-
0038476608
-
Benefits of targeting both pericytes and endothelial cells in the tumor vasculature with kinase inhibitors
-
DOI 10.1172/JCI200317929
-
Bergers G, Song S, Meyer-Morse N, Bergsland E, Hanahan D. Benefits of targeting both pericytes and endothelial cells in the tumor vasculature with kinase inhibitors. J Clin Invest 2003;111:1287-95. (Pubitemid 36554699)
-
(2003)
Journal of Clinical Investigation
, vol.111
, Issue.9
, pp. 1287-1295
-
-
Bergers, G.1
Song, S.2
Meyer-Morse, N.3
Bergsland, E.4
Hanahan, D.5
-
34
-
-
70149112112
-
Fyn and SRC are effectors of oncogenic epidermal growth factor receptor signaling in glioblastoma patients
-
Lu KV, Zhu S, Cvrljevic A, Huang TT, Sarkaria S, Ahkavan D, et al. Fyn and SRC are effectors of oncogenic epidermal growth factor receptor signaling in glioblastoma patients. Cancer Res 2009;69:6889-98.
-
(2009)
Cancer Res
, vol.69
, pp. 6889-6898
-
-
Lu, K.V.1
Zhu, S.2
Cvrljevic, A.3
Huang, T.T.4
Sarkaria, S.5
Ahkavan, D.6
-
35
-
-
0344420263
-
Contrasting in Vivo and in Vitro Fates of Glioblastoma Cell Subpopulations with Amplified EGFR
-
DOI 10.1002/gcc.10300
-
Pandita A, Aldape KD, Zadeh G, Guha A, James CD. Contrasting in vivo and in vitro fates of glioblastoma cell subpopulations with amplified EGFR. Genes Chromosomes Cancer 2004;39:29-36. (Pubitemid 37475250)
-
(2004)
Genes Chromosomes and Cancer
, vol.39
, Issue.1
, pp. 29-36
-
-
Pandita, A.1
Aldape, K.D.2
Zadeh, G.3
Guha, A.4
James, C.D.5
-
36
-
-
27744506881
-
Molecular study of malignant gliomas treated with epidermal growth factor receptor inhibitors: Tissue analysis from North American Brain Tumor Consortium trials 01-03 and 00-01
-
DOI 10.1158/1078-0432.CCR-05-0421
-
Lassman AB, Rossi MR, Razier JR, Abrey LE, Lieberman FS, Grefe CN, et al. Molecular study of malignant gliomas treated with epidermal growth factor receptor inhibitors: tissue analysis from north American brain tumor consortium trials 01-03 and 00-01. Clin Cancer Res 2005;11:7841-50. (Pubitemid 41611629)
-
(2005)
Clinical Cancer Research
, vol.11
, Issue.21
, pp. 7841-7850
-
-
Lassman, A.B.1
Rossi, M.R.2
Razier, J.R.3
Abrey, L.E.4
Lieberman, F.S.5
Grefe, C.N.6
Lamborn, K.7
Pao, W.8
Shih, A.H.9
Kuhn, J.G.10
Wilson, R.11
Nowak, N.J.12
Cowell, J.K.13
DeAngelis, L.M.14
Wen, P.15
Gilbert, M.R.16
Chang, S.17
Yung, W.A.18
Prados, M.19
Holland, E.C.20
more..
-
37
-
-
75749122223
-
A phase II trial of erlotinib in patients with recurrent malignant gliomas and nonprogressive glioblastoma multiforme postradiation therapy
-
Raizer JJ, Abrey LE, Lassman AB, Chang SM, Lamborn KR, Kuhn JG, et al. A phase II trial of erlotinib in patients with recurrent malignant gliomas and nonprogressive glioblastoma multiforme postradiation therapy. Neuro Oncol 2009;12:95-103.
-
(2009)
Neuro Oncol
, vol.12
, pp. 95-103
-
-
Raizer, J.J.1
Abrey, L.E.2
Lassman, A.B.3
Chang, S.M.4
Lamborn, K.R.5
Kuhn, J.G.6
-
38
-
-
33745828702
-
EGF-ERBB signalling: Towards the systems level
-
DOI 10.1038/nrm1962, PII NRM1962
-
Citri A, Yarden Y. EGF-ERBB signalling: towards the systems level. Nat Rev Mol Cell Biol 2006;7:505-16. (Pubitemid 44036456)
-
(2006)
Nature Reviews Molecular Cell Biology
, vol.7
, Issue.7
, pp. 505-516
-
-
Citri, A.1
Yarden, Y.2
-
39
-
-
36849068465
-
Evolvable signaling networks of receptor tyrosine kinases: Relevance of robustness to malignancy and to cancer therapy
-
Amit I, Wides R, Yarden Y. Evolvable signaling networks of receptor tyrosine kinases: relevance of robustness to malignancy and to cancer therapy. Mol Syst Biol 2007;3:151.
-
(2007)
Mol Syst Biol
, vol.3
, pp. 151
-
-
Amit, I.1
Wides, R.2
Yarden, Y.3
-
40
-
-
35348822482
-
Coactivation of receptor tyrosine kinases affects the response of tumor cells to targeted therapies
-
DOI 10.1126/science.1142946
-
Stommel JM, Kimmelman AC, Ying H, Nabioullin R, Ponugoti AH, Wiedemeyer R, et al. Coactivation of receptor tyrosine kinases affects the response of tumor cells to targeted therapies. Science 2007;318:287-90. (Pubitemid 47574858)
-
(2007)
Science
, vol.318
, Issue.5848
, pp. 287-290
-
-
Stommel, J.M.1
Kimmelman, A.C.2
Ying, H.3
Nabioullin, R.4
Ponugoti, A.H.5
Wiedemeyer, R.6
Stegh, A.H.7
Bradner, J.E.8
Ligon, K.L.9
Brennan, C.10
Chin, L.11
DePinho, R.A.12
-
41
-
-
77953663228
-
Only a subset of met-activated pathways are required to sustain oncogene addiction
-
Bertotti A, Burbridge MF, Gastaldi S, Galimi F, Torti D, Medico E, et al. Only a subset of met-activated pathways are required to sustain oncogene addiction. Sci Signal 2009;2:er11.
-
(2009)
Sci Signal
, vol.2
-
-
Bertotti, A.1
Burbridge, M.F.2
Gastaldi, S.3
Galimi, F.4
Torti, D.5
Medico, E.6
|