메뉴 건너뛰기




Volumn 4, Issue 11, 2012, Pages 1058-1081

Comparative antitumor effect of preventive versus therapeutic vaccines employing B16 melanoma cells genetically modified to express GM-CSF and B7.2 in a murine model

Author keywords

B7.2; Cancer vaccines; Gene therapy; GM CSF; Non viral

Indexed keywords

GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; IMMUNOGLOBULIN G; MELANOMA VACCINE;

EID: 84870573614     PISSN: 20726651     EISSN: None     Source Type: Journal    
DOI: 10.3390/toxins4111058     Document Type: Article
Times cited : (6)

References (68)
  • 1
    • 0033771031 scopus 로고    scopus 로고
    • Combination gene therapy using multiple immunomodulatory genes transferred by a defective infectious single-cycle herpes virus in squamous cell cancer
    • Kim, S.; Carew, J.F.; Kooby, D.A.; Shields, J.; Entwisle, C.; Patel, S.; Shah, J.P.; Fong, Y. Combination gene therapy using multiple immunomodulatory genes transferred by a defective infectious single-cycle herpes virus in squamous cell cancer. Cancer Gene Ther. 2000, 7, 1279-1285.
    • (2000) Cancer Gene Ther. , vol.7 , pp. 1279-1285
    • Kim, S.1    Carew, J.F.2    Kooby, D.A.3    Shields, J.4    Entwisle, C.5    Patel, S.6    Shah, J.P.7    Fong, Y.8
  • 2
    • 0031053562 scopus 로고    scopus 로고
    • A phase-I clinical study of autologous tumor cells plus interleukin-2-gene-transfected allogeneic fibroblasts as a vaccine in patients with cancer
    • Veelken, H.; Mackensen, A.; Lahn, M.; Kohler, G.; Becker, D.; Franke, B.; Brennscheidt, U.; Kulmburg, P.; Rosenthal, F.M.; Keller, H.; et al. A phase-I clinical study of autologous tumor cells plus interleukin-2-gene-transfected allogeneic fibroblasts as a vaccine in patients with cancer. Int. J. Cancer 1997, 70, 269-277.
    • (1997) Int. J. Cancer , vol.70 , pp. 269-277
    • Veelken, H.1    Mackensen, A.2    Lahn, M.3    Kohler, G.4    Becker, D.5    Franke, B.6    Brennscheidt, U.7    Kulmburg, P.8    Rosenthal, F.M.9    Keller, H.10
  • 4
    • 0035835377 scopus 로고    scopus 로고
    • Therapeutic vaccination against metastatic carcinoma by expression-modulated and immunomodified autologous tumor cells: A first clinical phase I/II trial
    • Wittig, B.; Marten, A.; Dorbic, T.; Weineck, S.; Min, H.; Niemitz, S.; Trojaneck, B.; Flieger, D.; Kruopis, S.; Albers, A.; et al. Therapeutic vaccination against metastatic carcinoma by expression-modulated and immunomodified autologous tumor cells: A first clinical phase I/II trial. Hum. Gene Ther. 2001, 12, 267-278.
    • (2001) Hum. Gene Ther. , vol.12 , pp. 267-278
    • Wittig, B.1    Marten, A.2    Dorbic, T.3    Weineck, S.4    Min, H.5    Niemitz, S.6    Trojaneck, B.7    Flieger, D.8    Kruopis, S.9    Albers, A.10
  • 5
    • 0031749740 scopus 로고    scopus 로고
    • Vaccination with IL-7 gene-modified autologous melanoma cells can enhance the anti-melanoma lytic activity in peripheral blood of patients with a good clinical performance status: A clinical phase I study
    • Moller, P.; Sun, Y.; Dorbic, T.; Alijagic, S.; Makki, A.; Jurgovsky, K.; Schroff, M.; Henz, B.M.; Wittig, B.; Schadendorf, D. Vaccination with IL-7 gene-modified autologous melanoma cells can enhance the anti-melanoma lytic activity in peripheral blood of patients with a good clinical performance status: A clinical phase I study. Br. J. Cancer 1998, 77, 1907-1916.
    • (1998) Br. J. Cancer , vol.77 , pp. 1907-1916
    • Moller, P.1    Sun, Y.2    Dorbic, T.3    Alijagic, S.4    Makki, A.5    Jurgovsky, K.6    Schroff, M.7    Henz, B.M.8    Wittig, B.9    Schadendorf, D.10
  • 6
    • 0036181209 scopus 로고    scopus 로고
    • Vaccination of stage IV patients with allogeneic IL-4-or IL-2-gene-transduced melanoma cells generates functional antibodies against vaccinating and autologous melanoma cells
    • Maio, M.; Fonsatti, E.; Lamaj, E.; Altomonte, M.; Cattarossi, I.; Santantonio, C.; Melani, C.; Belli, F.; Arienti, F.; Colombo, M.P.; et al. Vaccination of stage IV patients with allogeneic IL-4-or IL-2-gene-transduced melanoma cells generates functional antibodies against vaccinating and autologous melanoma cells. Cancer Immunol. Immunother. 2002, 51, 9-14.
    • (2002) Cancer Immunol. Immunother. , vol.51 , pp. 9-14
    • Maio, M.1    Fonsatti, E.2    Lamaj, E.3    Altomonte, M.4    Cattarossi, I.5    Santantonio, C.6    Melani, C.7    Belli, F.8    Arienti, F.9    Colombo, M.P.10
  • 11
    • 84861233216 scopus 로고    scopus 로고
    • Sequential immunotherapy by vaccination with GM-CSF-expressing glioma cells and CTLA-4 blockade effectively treats established murine intracranial tumors
    • Agarwalla, P.; Barnard, Z.; Fecci, P.; Dranoff, G.; Curry, W.T., Jr. Sequential immunotherapy by vaccination with GM-CSF-expressing glioma cells and CTLA-4 blockade effectively treats established murine intracranial tumors. J. Immunother. 2012, 35, 385-389.
    • (2012) J. Immunother. , vol.35 , pp. 385-389
    • Agarwalla, P.1    Barnard, Z.2    Fecci, P.3    Dranoff, G.4    Curry Jr., W.T.5
  • 13
    • 84870507277 scopus 로고    scopus 로고
    • The boosting effect of co-transduction with cytokine genes on cancer vaccine therapy using genetically modified dendritic cells expressing tumor-associated antigen
    • Ojima, T.; Iwahashi, M.; Nakamura, M.; Matsuda, K.; Naka, T.; Nakamori, M.; Ueda, K.; Ishida, K.; Yamaue, H. The boosting effect of co-transduction with cytokine genes on cancer vaccine therapy using genetically modified dendritic cells expressing tumor-associated antigen. Int. J. Oncol. 2006, 289, 47-53.
    • (2006) Int. J. Oncol. , vol.289 , pp. 47-53
    • Ojima, T.1    Iwahashi, M.2    Nakamura, M.3    Matsuda, K.4    Naka, T.5    Nakamori, M.6    Ueda, K.7    Ishida, K.8    Yamaue, H.9
  • 14
    • 0027538181 scopus 로고
    • Vaccination with irradiated tumor cells engineered to secrete granulocyte-Macrophage colony-stimulating factor (GM-CSF) stimulates potent, specific, and long-lasting antitumor immunity in multiple murine tumor model systems, including malignant melanoma
    • Dranoff, G.; Jaffee, E.; Lazenby, A.; Golumbek, P.; Levitsky, H.; Brose, K.; Jackson, V.; Hamada, H.; Pardoll, D.; Mulligan, R.C. Vaccination with irradiated tumor cells engineered to secrete granulocyte-Macrophage colony-stimulating factor (GM-CSF) stimulates potent, specific, and long-lasting antitumor immunity in multiple murine tumor model systems, including malignant melanoma. Proc. Natl. Acad. Sci. USA 1993, 90, 3539-3543.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 3539-3543
    • Dranoff, G.1    Jaffee, E.2    Lazenby, A.3    Golumbek, P.4    Levitsky, H.5    Brose, K.6    Jackson, V.7    Hamada, H.8    Pardoll, D.9    Mulligan, R.C.10
  • 15
    • 33847258205 scopus 로고    scopus 로고
    • Opposite immune functions of GM-CSF administered as vaccine adjuvant in cancer patients
    • Parmiani, G.; Castelli, C.; Pilla, L.; Santinami, M.; Colombo, M.P.; Rivoltini, L. Opposite immune functions of GM-CSF administered as vaccine adjuvant in cancer patients. Ann. Oncol. 2007, 18, 226-232.
    • (2007) Ann. Oncol. , vol.18 , pp. 226-232
    • Parmiani, G.1    Castelli, C.2    Pilla, L.3    Santinami, M.4    Colombo, M.P.5    Rivoltini, L.6
  • 16
    • 0033168146 scopus 로고    scopus 로고
    • Transfection of immature murine bone marrow-derived dendritic cells with the granulocyte-macrophage colony-stimulating factor gene potently enhances their in vivo antigen-presenting capacity
    • Curiel-Lewandrowski, C.; Mahnke, K.; Labeur, M.; Roters, B.; Schmidt, W.; Granstein, R.D.; Luger, T.A.; Schwarz, T.; Grabbe, S. Transfection of immature murine bone marrow-derived dendritic cells with the granulocyte-macrophage colony-stimulating factor gene potently enhances their in vivo antigen-presenting capacity. J. Immunol. 1999, 163, 174-183.
    • (1999) J. Immunol. , vol.163 , pp. 174-183
    • Curiel-Lewandrowski, C.1    Mahnke, K.2    Labeur, M.3    Roters, B.4    Schmidt, W.5    Granstein, R.D.6    Luger, T.A.7    Schwarz, T.8    Grabbe, S.9
  • 17
    • 0031965021 scopus 로고    scopus 로고
    • Gene immunotherapy in murine acute myeloid leukemia: Granulocyte-macrophage colony-stimulating factor tumor cell vaccines elicit more potent antitumor immunity compared with B7 family and other cytokine vaccines
    • Dunussi-Joannopoulos, K.; Dranoff, G.; Weinstein, H.J.; Ferrara, J.L.; Bierer, B.E.; Croop, J.M. Gene immunotherapy in murine acute myeloid leukemia: Granulocyte-macrophage colony-stimulating factor tumor cell vaccines elicit more potent antitumor immunity compared with B7 family and other cytokine vaccines. Blood 1998, 91, 222-230.
    • (1998) Blood , vol.91 , pp. 222-230
    • Dunussi-Joannopoulos, K.1    Dranoff, G.2    Weinstein, H.J.3    Ferrara, J.L.4    Bierer, B.E.5    Croop, J.M.6
  • 18
    • 0141576738 scopus 로고    scopus 로고
    • Vaccination with irradiated, autologous melanoma cells engineered to secrete granulocyte-macrophage colony-stimulating factor by adenoviral-mediated gene transfer augments antitumor immunity in patients with metastatic melanoma
    • Soiffer, R.; Hodi, F.S.; Haluska, F.; Jung, K.; Gillessen, S.; Singer, S.; Tanabe, K.; Duda, R.; Mentzer, S.; Jaklitsch, M.; et al. Vaccination with irradiated, autologous melanoma cells engineered to secrete granulocyte-macrophage colony-stimulating factor by adenoviral-mediated gene transfer augments antitumor immunity in patients with metastatic melanoma. J. Clin. Oncol. 2003, 21, 3343-3350.
    • (2003) J. Clin. Oncol. , vol.21 , pp. 3343-3350
    • Soiffer, R.1    Hodi, F.S.2    Haluska, F.3    Jung, K.4    Gillessen, S.5    Singer, S.6    Tanabe, K.7    Duda, R.8    Mentzer, S.9    Jaklitsch, M.10
  • 20
    • 0037441842 scopus 로고    scopus 로고
    • Vaccination with irradiated autologous tumor cells engineered to secrete granulocyte-macrophage colony-stimulating factor augments antitumor immunity in some patients with metastatic non-small-cell lung carcinoma
    • Salgia, R.; Lynch, T.; Skarin, A.; Lucca, J.; Lynch, C.; Jung, K.; Hodi, F.S.; Jaklitsch, M.; Mentzer, S.; Swanson, S.; et al. Vaccination with irradiated autologous tumor cells engineered to secrete granulocyte-macrophage colony-stimulating factor augments antitumor immunity in some patients with metastatic non-small-cell lung carcinoma. J. Clin. Oncol. 2003, 21, 624-630.
    • (2003) J. Clin. Oncol. , vol.21 , pp. 624-630
    • Salgia, R.1    Lynch, T.2    Skarin, A.3    Lucca, J.4    Lynch, C.5    Jung, K.6    Hodi, F.S.7    Jaklitsch, M.8    Mentzer, S.9    Swanson, S.10
  • 21
    • 0032573225 scopus 로고    scopus 로고
    • Vaccination with irradiated autologous melanoma cells engineered to secrete human granulocyte-macrophage colony-stimulating factor generates potent antitumor immunity in patients with metastatic melanoma
    • Soiffer, R.; Lynch, T.; Mihm, M.; Jung, K.; Rhuda, C.; Schmollinger, J.C.; Hodi, F.S.; Liebster, L.; Lam, P.; Mentzer, S.; et al. Vaccination with irradiated autologous melanoma cells engineered to secrete human granulocyte-macrophage colony-stimulating factor generates potent antitumor immunity in patients with metastatic melanoma. Proc. Natl. Acad. Sci. USA 1998, 95, 13141-13146.
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 13141-13146
    • Soiffer, R.1    Lynch, T.2    Mihm, M.3    Jung, K.4    Rhuda, C.5    Schmollinger, J.C.6    Hodi, F.S.7    Liebster, L.8    Lam, P.9    Mentzer, S.10
  • 23
    • 0035152718 scopus 로고    scopus 로고
    • Novel allogeneic granulocyte-macrophage colony-stimulating factor-Secreting tumor vaccine for pancreatic cancer: A phase I trial of safety and immune activation
    • Jaffee, E.M.; Hruban, R.H.; Biedrzycki, B.; Laheru, D.; Schepers, K.; Sauter, P.R.; Goemann, M.; Coleman, J.; Grochow, L.; Donehower, R.C.; et al. Novel allogeneic granulocyte-macrophage colony-stimulating factor-Secreting tumor vaccine for pancreatic cancer: A phase I trial of safety and immune activation. J. Clin. Oncol. 2001, 19, 145-156.
    • (2001) J. Clin. Oncol. , vol.19 , pp. 145-156
    • Jaffee, E.M.1    Hruban, R.H.2    Biedrzycki, B.3    Laheru, D.4    Schepers, K.5    Sauter, P.R.6    Goemann, M.7    Coleman, J.8    Grochow, L.9    Donehower, R.C.10
  • 24
    • 0036005892 scopus 로고    scopus 로고
    • GM-CSF-based cellular vaccines: A review of the clinical experience
    • Borrello, I.; Pardoll, D. GM-CSF-based cellular vaccines: A review of the clinical experience. Cytokine Growth Factor Rev. 2002, 13, 185-193.
    • (2002) Cytokine Growth Factor Rev. , vol.13 , pp. 185-193
    • Borrello, I.1    Pardoll, D.2
  • 25
    • 0347383732 scopus 로고    scopus 로고
    • Complete tumor prevention by engineered tumor cell vaccines employing nonviral vectors
    • Moret-Tatay, I.; Diaz, J.; Marco, F.M.; Crespo, A.; Aliño, S.F. Complete tumor prevention by engineered tumor cell vaccines employing nonviral vectors. Cancer Gene Ther. 2003, 10, 887-897.
    • (2003) Cancer Gene Ther. , vol.10 , pp. 887-897
    • Moret-Tatay, I.1    Diaz, J.2    Marco, F.M.3    Crespo, A.4    Aliño, S.F.5
  • 26
    • 33646493653 scopus 로고    scopus 로고
    • Nonviral therapeutic cell vaccine mediates potent antitumor effects
    • Moret-Tatay, I.; Sanmartín, I.; Marco, F.M.; Díaz, J.; Aliño, S.F. Nonviral therapeutic cell vaccine mediates potent antitumor effects. Vaccine 2006, 24, 3937-3945.
    • (2006) Vaccine , vol.24 , pp. 3937-3945
    • Moret-Tatay, I.1    Sanmartín, I.2    Marco, F.M.3    Díaz, J.4    Aliño, S.F.5
  • 27
    • 33947582051 scopus 로고    scopus 로고
    • Antigens and cytokine genes in antitumor vaccines: The importance of the temporal delivery sequence in antitumor signals
    • Herrero, M.J.; Botella, R.; Dasí, F.; Algás, R.; Sánchez, M.; Aliño, S.F. Antigens and cytokine genes in antitumor vaccines: The importance of the temporal delivery sequence in antitumor signals. Ann. N. Y. Acad. Sci. 2006, 1091, 412-424.
    • (2006) Ann. N.Y. Acad. Sci. , vol.1091 , pp. 412-424
    • Herrero, M.J.1    Botella, R.2    Dasí, F.3    Algás, R.4    Sánchez, M.5    Aliño, S.F.6
  • 28
    • 84862805746 scopus 로고    scopus 로고
    • A novel therapeutic vaccine of mouse GM-CSF surface modified MB49 cells against metastatic bladder cancer
    • Zhang, X.; Shi, X.; Li, J.; Hu, Z.; Zhou, D.; Gao, J.; Tan, W. A novel therapeutic vaccine of mouse GM-CSF surface modified MB49 cells against metastatic bladder cancer. J. Urol. 2012, 187, 1071-1079.
    • (2012) J. Urol. , vol.187 , pp. 1071-1079
    • Zhang, X.1    Shi, X.2    Li, J.3    Hu, Z.4    Zhou, D.5    Gao, J.6    Tan, W.7
  • 29
    • 0025735629 scopus 로고
    • The dendritic cell system and its role in immunogenicity
    • Steinman, R.M. The dendritic cell system and its role in immunogenicity. Annu. Rev. Immunol. 1991, 9, 271-296.
    • (1991) Annu. Rev. Immunol. , vol.9 , pp. 271-296
    • Steinman, R.M.1
  • 30
    • 0031885545 scopus 로고    scopus 로고
    • Tumor cell expression of B7 costimulatory molecules and interleukin-12 or granulocyte-macrophage colony-stimulating factor induces a local antitumor response and may generate systemic protective immunity
    • Chong, H.; Todryk, S.; Hutchinson, G.; Hart, I.R.; Vile, R.G. Tumor cell expression of B7 costimulatory molecules and interleukin-12 or granulocyte-macrophage colony-stimulating factor induces a local antitumor response and may generate systemic protective immunity. Gene Ther. 1998, 5, 223-232.
    • (1998) Gene Ther. , vol.5 , pp. 223-232
    • Chong, H.1    Todryk, S.2    Hutchinson, G.3    Hart, I.R.4    Vile, R.G.5
  • 31
    • 0035837648 scopus 로고    scopus 로고
    • Enhancement of natural killer cell-mediated cytotoxicity by coexpression of GM-CSF/B70 in hepatoma
    • Kim, K.Y.; Kang, M.A.; Nam, M.J. Enhancement of natural killer cell-mediated cytotoxicity by coexpression of GM-CSF/B70 in hepatoma. Cancer Lett. 2001, 166, 33-40.
    • (2001) Cancer Lett. , vol.166 , pp. 33-40
    • Kim, K.Y.1    Kang, M.A.2    Nam, M.J.3
  • 33
    • 0036687281 scopus 로고    scopus 로고
    • Human autologous in vitro models of glioma immunogene therapy using B7-2, GM-CSF and IL-12
    • Parney, I.F.; Farr-Jones, M.A.; Kane, K.; Chang, L.J.; Petruk, K.C. Human autologous in vitro models of glioma immunogene therapy using B7-2, GM-CSF and IL-12. Can. J. Neurol. Sci. 2002, 29, 267-275.
    • (2002) Can. J. Neurol. Sci. , vol.29 , pp. 267-275
    • Parney, I.F.1    Farr-Jones, M.A.2    Kane, K.3    Chang, L.J.4    Petruk, K.C.5
  • 34
    • 33646860113 scopus 로고    scopus 로고
    • Technical hurdles in a pilot clinical trial of combined B7-2 and GM-CSF immunogene therapy for glioblastomas and melanomas
    • Parney, I.F.; Chang, L.J.; Farr-Jones, M.A.; Hao, C.; Smylie, M.; Petruk, K.C. Technical hurdles in a pilot clinical trial of combined B7-2 and GM-CSF immunogene therapy for glioblastomas and melanomas. J. Neurooncol. 2006, 78, 71-80.
    • (2006) J. Neurooncol. , vol.78 , pp. 71-80
    • Parney, I.F.1    Chang, L.J.2    Farr-Jones, M.A.3    Hao, C.4    Smylie, M.5    Petruk, K.C.6
  • 35
    • 10744226368 scopus 로고    scopus 로고
    • Phase I/II Clinical trial of a nonreplicative vaccinia virus expressing multiple HLA-A0201-restricted tumor-associated epitopes and costimulatory molecules in metastatic melanoma patients
    • Zajac, P.; Oertli, D.; Marti, W.; Adamina, M.; Bolli, M.; Guller, U.; Noppen, C.; Padovan, E.; Schultz-Thater, E.; Heberer, M.; et al. Phase I/II Clinical trial of a nonreplicative vaccinia virus expressing multiple HLA-A0201-restricted tumor-associated epitopes and costimulatory molecules in metastatic melanoma patients. Hum. Gene Ther. 2003, 14, 1497-1510.
    • (2003) Hum. Gene Ther. , vol.14 , pp. 1497-1510
    • Zajac, P.1    Oertli, D.2    Marti, W.3    Adamina, M.4    Bolli, M.5    Guller, U.6    Noppen, C.7    Padovan, E.8    Schultz-Thater, E.9    Heberer, M.10
  • 36
    • 1942420680 scopus 로고    scopus 로고
    • B7-2 expression above a threshold elicits anti-tumor immunity as effective as interleukin-12 and prolongs survival in murine B-cell lymphoma
    • Pizzoferrato, E. B7-2 expression above a threshold elicits anti-tumor immunity as effective as interleukin-12 and prolongs survival in murine B-cell lymphoma. Int. J. Cancer 2004, 110, 61-69.
    • (2004) Int. J. Cancer , vol.110 , pp. 61-69
    • Pizzoferrato, E.1
  • 37
    • 0032610834 scopus 로고    scopus 로고
    • Granulocyte-macrophage colony-stimulating factor (GM-CSF) secreted by cDNA-transfected tumor cells induces a more potent antitumor response than exogenous GM-CSF
    • Shi, F.S.; Weber, S.; Gan, J.; Rakhmilevich, A.L.; Mahvi, D.M. Granulocyte-macrophage colony-stimulating factor (GM-CSF) secreted by cDNA-transfected tumor cells induces a more potent antitumor response than exogenous GM-CSF. Cancer Gene Ther. 1999, 6, 81-88.
    • (1999) Cancer Gene Ther. , vol.6 , pp. 81-88
    • Shi, F.S.1    Weber, S.2    Gan, J.3    Rakhmilevich, A.L.4    Mahvi, D.M.5
  • 39
    • 4344590947 scopus 로고    scopus 로고
    • High-dose granulocyte-macrophage colony-stimulating factor-producing vaccines impair the immune response through the recruitment of myeloid suppressor cells
    • Serafini, P.; Carbley, R.; Noonan, K.A.; Tan, G.; Bronte, V.; Borrello, I. High-dose granulocyte-macrophage colony-stimulating factor-producing vaccines impair the immune response through the recruitment of myeloid suppressor cells. Cancer Res. 2004, 64, 6337-6343.
    • (2004) Cancer Res. , vol.64 , pp. 6337-6343
    • Serafini, P.1    Carbley, R.2    Noonan, K.A.3    Tan, G.4    Bronte, V.5    Borrello, I.6
  • 41
    • 35448994739 scopus 로고    scopus 로고
    • 5 minutes-averaged values of clearness index and relative optical air mass
    • 5 minutes-averaged values of clearness index and relative optical air mass. Theor. Appl. Climatol. 2007, 90, 235-248.
    • (2007) Theor Appl. Climatol. , vol.90 , pp. 235-248
  • 42
    • 34748849509 scopus 로고    scopus 로고
    • Vaccine therapy for melanoma: Current status and future directions
    • Terando, A.M.; Faries, M.B.; Morton, D.L. Vaccine therapy for melanoma: current status and future directions. Vaccine 2007, 25, B4-B16.
    • (2007) Vaccine , vol.25
    • Terando, A.M.1    Faries, M.B.2    Morton, D.L.3
  • 43
    • 33645286546 scopus 로고    scopus 로고
    • Regulatory T cells, tumor immunity and immunotherapy
    • Zou, W. Regulatory T cells, tumor immunity and immunotherapy. Nat. Rev. Immunol. 2006, 6, 295-307.
    • (2006) Nat. Rev. Immunol. , vol.6 , pp. 295-307
    • Zou, W.1
  • 44
    • 30144443269 scopus 로고    scopus 로고
    • Paradoxical roles of the immune system during cancer development
    • De Visser, K.; Eichten, A.; Coussens, L. Paradoxical roles of the immune system during cancer development. Nat. Rev. Cancer 2006, 6, 24-37.
    • (2006) Nat. Rev. Cancer , vol.6 , pp. 24-37
    • De Visser, K.1    Eichten, A.2    Coussens, L.3
  • 45
    • 31344474166 scopus 로고    scopus 로고
    • Myeloid suppressor cells in cancer: Recruitment, phenotype, properties, and mechanisms of immune suppression
    • Serafini, P.; Borrello, I.; Bronte, V. Myeloid suppressor cells in cancer: Recruitment, phenotype, properties, and mechanisms of immune suppression. Semin. Cancer Biol. 2006, 16, 53-65.
    • (2006) Semin. Cancer Biol. , vol.16 , pp. 53-65
    • Serafini, P.1    Borrello, I.2    Bronte, V.3
  • 46
    • 0030300137 scopus 로고    scopus 로고
    • The role of B7-1/B7-2:CD28/CTLA-4 pathways in the prevention of anergy, induction of productive immunity and down-regulation of the immune response
    • Bossiotis, V.A.; Freeman, G.J.; Gribben, J.G.; Badler, L.M. The role of B7-1/B7-2:CD28/CTLA-4 pathways in the prevention of anergy, induction of productive immunity and down-regulation of the immune response. Immunol. Rev. 1996, 15, 5-26.
    • (1996) Immunol. Rev. , vol.15 , pp. 5-26
    • Bossiotis, V.A.1    Freeman, G.J.2    Gribben, J.G.3    Badler, L.M.4
  • 47
    • 0030300154 scopus 로고    scopus 로고
    • The complexities of T-cell co-stimulation: CD28 and beyond
    • Sperling, A.; Bluestone, J.A. The complexities of T-cell co-stimulation: CD28 and beyond. Immunol. Rev. 1996, 153, 155-182.
    • (1996) Immunol. Rev. , vol.153 , pp. 155-182
    • Sperling, A.1    Bluestone, J.A.2
  • 48
    • 0030001318 scopus 로고    scopus 로고
    • Regulation of T cell receptor signalling by tyrosine phosphatase SYP association with CTLA-4
    • Marengere, L.E.M.; Waterhouse, H.W.; Duncan, G.S.; Mittrucker, H.W.; Feng, G.S.; Mak, T.W. Regulation of T cell receptor signalling by tyrosine phosphatase SYP association with CTLA-4. Science 1996, 272, 1170-1173.
    • (1996) Science , vol.272 , pp. 1170-1173
    • Marengere, L.E.M.1    Waterhouse, H.W.2    Duncan, G.S.3    Mittrucker, H.W.4    Feng, G.S.5    Mak, T.W.6
  • 49
    • 0033168037 scopus 로고    scopus 로고
    • Tumor rejection by in vivo administration of anti-CD25 (interleukin-2 receptor α) monoclonal antibody
    • Onizuka, S.; Tawara, I.; Shimizu, J.; Sakaguchi, S.; Fujita, T.; Nakayama, E. Tumor rejection by in vivo administration of anti-CD25 (interleukin-2 receptor α) monoclonal antibody. Cancer Res. 1999, 59, 3128-3133.
    • (1999) Cancer Res. , vol.59 , pp. 3128-3133
    • Onizuka, S.1    Tawara, I.2    Shimizu, J.3    Sakaguchi, S.4    Fujita, T.5    Nakayama, E.6
  • 52
    • 70350496784 scopus 로고    scopus 로고
    • Clinical use of anti-CD25 antibody daclizumab to enhance immune responses to tumor antigen vaccination by targeting regulatory T cells
    • Rech, A.J.; Vonderheide, R.H. Clinical use of anti-CD25 antibody daclizumab to enhance immune responses to tumor antigen vaccination by targeting regulatory T cells. Ann. N. Y. Acad. Sci. 2009, 1174, 99-106.
    • (2009) Ann. N.Y. Acad. Sci. , vol.1174 , pp. 99-106
    • Rech, A.J.1    Vonderheide, R.H.2
  • 55
    • 0029947568 scopus 로고    scopus 로고
    • Enhancement of antitumor immunity by CTLA-4 blockade
    • Leach, D.R.; Krummel, M.F.; Allison, J.P. Enhancement of antitumor immunity by CTLA-4 blockade. Science 1996, 271, 1734-1736.
    • (1996) Science , vol.271 , pp. 1734-1736
    • Leach, D.R.1    Krummel, M.F.2    Allison, J.P.3
  • 56
    • 81055127514 scopus 로고    scopus 로고
    • Anti-CTLA4 monoclonal antibodies: The past and the future in clinical application
    • Ascierto, P.A.; Marincola, F.M.; Ribas, A. Anti-CTLA4 monoclonal antibodies: The past and the future in clinical application. J. Transl. Med. 2011, 9, 196.
    • (2011) J. Transl. Med. , vol.9 , pp. 196
    • Ascierto, P.A.1    Marincola, F.M.2    Ribas, A.3
  • 57
    • 27444435581 scopus 로고    scopus 로고
    • Inability of a fusion protein of IL-2 and diphtheria toxin (Denileukin Diftitox, DAB389IL2-ONTAK) to eliminate regulatory T lymphocytes in patients with melanoma
    • Attia, P.; Maker, A.V.; Haworth, L.R.; Rogers-Freezer, L.; Rosenberg, S.A. Inability of a fusion protein of IL-2 and diphtheria toxin (Denileukin Diftitox, DAB389IL2-ONTAK) to eliminate regulatory T lymphocytes in patients with melanoma. J. Immunother. 2005, 28, 582-592.
    • (2005) J. Immunother. , vol.28 , pp. 582-592
    • Attia, P.1    Maker, A.V.2    Haworth, L.R.3    Rogers-Freezer, L.4    Rosenberg, S.A.5
  • 59
    • 66249141668 scopus 로고    scopus 로고
    • Costimulation as a platform for the development of vaccines: A peptide-based vaccine containing a novel form of 4-1BB ligand eradicates established tumors
    • Sharma, R.K.; Elpek, K.G.; Yolcu, E.S.; Schabowsky, R.H.; Zhao, H.; Bandura-Morgan, L.; Shirwan, H. Costimulation as a platform for the development of vaccines: A peptide-based vaccine containing a novel form of 4-1BB ligand eradicates established tumors. Cancer Res. 2009, 69, 4319-4326.
    • (2009) Cancer Res. , vol.69 , pp. 4319-4326
    • Sharma, R.K.1    Elpek, K.G.2    Yolcu, E.S.3    Schabowsky, R.H.4    Zhao, H.5    Bandura-Morgan, L.6    Shirwan, H.7
  • 62
  • 63
    • 33645500590 scopus 로고    scopus 로고
    • In vivo disruption of tolerogenic cross-presentation mechanisms uncovers an effective T-cell activation by Bcell lymphomas leading to antitumor immunity
    • Horna, P.; Cuenca, A.; Cheng, F.; Brayer, J.; Wang, H.W.; Borrello, I.; Levitsky, H.; Sotomayor, E.M. In vivo disruption of tolerogenic cross-presentation mechanisms uncovers an effective T-cell activation by Bcell lymphomas leading to antitumor immunity. Blood 2006, 107, 2871-2878.
    • (2006) Blood , vol.107 , pp. 2871-2878
    • Horna, P.1    Cuenca, A.2    Cheng, F.3    Brayer, J.4    Wang, H.W.5    Borrello, I.6    Levitsky, H.7    Sotomayor, E.M.8
  • 64
    • 33751531874 scopus 로고    scopus 로고
    • Phosphodiesterase-5 inhibition augments endogenous antitumor immunity by reducing myeloid-derived suppressor cell function
    • Serafini, P.; Meckel, K.; Kelso, M.; Noonan, K.; Califano, J.; Koch, W.; Dolcetti, L.; Bronte, V.; Borrello, I. Phosphodiesterase-5 inhibition augments endogenous antitumor immunity by reducing myeloid-derived suppressor cell function. J. Exp. Med. 2006, 203, 2691-2702.
    • (2006) J. Exp. Med. , vol.203 , pp. 2691-2702
    • Serafini, P.1    Meckel, K.2    Kelso, M.3    Noonan, K.4    Califano, J.5    Koch, W.6    Dolcetti, L.7    Bronte, V.8    Borrello, I.9
  • 65
    • 33749427617 scopus 로고    scopus 로고
    • Myeloid supresor cells regulate the adaptive immune response to cancer
    • Frey, A.B. Myeloid supresor cells regulate the adaptive immune response to cancer. J. Clin. Invest. 2006, 116, 2587-2590.
    • (2006) J. Clin. Invest. , vol.116 , pp. 2587-2590
    • Frey, A.B.1
  • 66
    • 34447258415 scopus 로고    scopus 로고
    • Identification of a new subset of myeloid supresor cells in Peripherals blood of melanoma patients with modulation by a GM-CSF-based antitumor vaccine
    • Filipazzi, P.; Valenti, R.; Huber, V.; Pilla, L.; Canese, P.; Iero, M.; Castelli, C.; Mariani, L.; Parmiani, G.; Rivoltini, L. Identification of a new subset of myeloid supresor cells in Peripherals blood of melanoma patients with modulation by a GM-CSF-based antitumor vaccine. J. Clin. Oncol. 2007, 25, 2546-2553.
    • (2007) J. Clin. Oncol. , vol.25 , pp. 2546-2553
    • Filipazzi, P.1    Valenti, R.2    Huber, V.3    Pilla, L.4    Canese, P.5    Iero, M.6    Castelli, C.7    Mariani, L.8    Parmiani, G.9    Rivoltini, L.10
  • 67
    • 34447621409 scopus 로고    scopus 로고
    • Transfection pathways of nonspecific and targeted PEI-polyplexes
    • Guillem, V.M.; Aliño, S.F. Transfection pathways of nonspecific and targeted PEI-polyplexes. Gene Ther. Mol. Biol. 2004, 8, 369-384.
    • (2004) Gene Ther. Mol. Biol. , vol.8 , pp. 369-384
    • Guillem, V.M.1    Aliño, S.F.2
  • 68
    • 0019887744 scopus 로고
    • Phase separation of integral membrane proteins in Triton X-114 solution
    • Bordier, C. Phase separation of integral membrane proteins in Triton X-114 solution. J. Biol. Chem. 1981, 25, 1604-1607.
    • (1981) J. Biol. Chem. , vol.25 , pp. 1604-1607
    • Bordier, C.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.