Copper/titanium catalysis forms fully substituted carbon centers from the direct coupling of acyclic ketones, amines, and alkynes

Angewandte Chemie - International Edition

Volumn 51, Issue 49, 2012, Pages 12289-12292

  Pierce, Conor J ^a   Nguyen, Mary ^a   Larsen, Catharine H ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

alkynes; amines; cooperative effects; ketones; multicomponent reactions

Indexed keywords

ACYCLIC KETONES; ALKYNES; COOPERATIVE EFFECTS; COPPER/TITANIUM; DIRECT COUPLING; DIVERSE RANGE; ELECTROPHILES; KETIMINES; METAL SYSTEMS; MULTI-COMPONENT REACTIONS; PROPARGYLAMINES; SOLVENT FREE CONDITIONS; SUBSTITUTED CARBONS; TERMINAL ALKYNE; THREE-COMPONENT COUPLING;

ACETYLENE; AMINES; CATALYSIS;

KETONES;

ALKYNE; AMINE; CARBON; COPPER; CYCLOHEXANONE DERIVATIVE; DRUG DERIVATIVE; KETONE; PARGYLINE; PROPARGYLAMINE; PROPYLAMINE; TITANIUM;

ARTICLE; CATALYSIS; CHEMISTRY; SYNTHESIS;

ALKYNES; AMINES; CARBON; CATALYSIS; COPPER; CYCLOHEXANONES; KETONES; PARGYLINE; PROPYLAMINES; TITANIUM;

EID: 84870560725     PISSN: 14337851     EISSN: 15213773     Source Type: Journal    
DOI: 10.1002/anie.201206674     Document Type: Article

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