P53-PGC-1α pathway mediates oxidative mitochondrial damage and cardiomyocyte necrosis induced by monoamine oxidase-a upregulation: Role in chronic left ventricular dysfunction in mice

Antioxidants and Redox Signaling

Volumn 18, Issue 1, 2013, Pages 5-18

  Villeneuve, Christelle ^a,b   Guilbeau Frugier, Céline ^a,b   Sicard, Pierre ^a,b   Lairez, Olivier ^a,b   Ordener, Catherine ^a,b   Duparc, Thibaut ^a,b   De Paulis, Damien ^c,d   Couderc, Bettina ^b   Spreux Varoquaux, Odile ^e   Tortosa, Florence ^a,b   Garnier, Anne ^f   Knauf, Claude ^a,b   Valet, Philippe ^a,b   Borchi, Elisabetta ^g   Nediani, Chiara ^g   Gharib, Abdallah ^c,d   Ovize, Michel ^c,d   Delisle, Marie Bernadette ^a,b   Parini, Angelo ^a,b   Mialet Perez, Jeanne ^a,b  

^a University Hospital of Toulouse   (France)

^b UNIVERSITÉ PAUL SABATIER   (France)

^c UNIVERSITÉ LYON 1   (France)

^d LOUIS PRADEL HOSPITAL   (France)

^e LABORATOIRE DES SCIENCES DU CLIMAT ET DE L ENVIRONNEMENT   (France)

^f INSERM   (France)

^g UNIVERSITY OF FLORENCE   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLCYSTEINE; ADENOSINE TRIPHOSPHATE; AMINE OXIDASE (FLAVIN CONTAINING) ISOENZYME A; CLORGYLINE; HYDROGEN PEROXIDE; MITOCHONDRIAL DNA; NORADRENALIN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1ALPHA; PROTEIN P53; SEROTONIN; TROPONIN I;

AGING; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL DAMAGE; CELL DEATH; CELL SURVIVAL; CONGESTIVE CARDIOMYOPATHY; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME BLOOD LEVEL; ENZYME INDUCTION; GENE OVEREXPRESSION; HEART DILATATION; HEART FUNCTION; HEART HYPERTROPHY; HEART LEFT VENTRICLE FAILURE; HEART MITOCHONDRION; HEART MUSCLE CELL; HEART MUSCLE FIBROSIS; HEART MUSCLE NECROSIS; HEART PROTECTION; IN VITRO STUDY; INTRACELLULAR SIGNALING; LONG TERM CARE; MALE; MITOCHONDRIAL RESPIRATION; MOUSE; NEWBORN; NONHUMAN; NUCLEOTIDE SEQUENCE; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN DEPLETION; RAT; RECEPTOR DOWN REGULATION;

ANIMALS; CARDIOMYOPATHY, DILATED; CELLS, CULTURED; CHRONIC DISEASE; ENZYME INDUCTION; FIBROSIS; HEART VENTRICLES; HYPERTROPHY, LEFT VENTRICULAR; MALE; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; MITOCHONDRIA, HEART; MONOAMINE OXIDASE; MYOCYTES, CARDIAC; NECROSIS; OXIDATION-REDUCTION; OXIDATIVE STRESS; RATS; RATS, SPRAGUE-DAWLEY; TRANS-ACTIVATORS; TUMOR SUPPRESSOR PROTEIN P53; UP-REGULATION; VENTRICULAR DYSFUNCTION, LEFT;

ADENOVIRIDAE; MUS; MUS MUSCULUS;

EID: 84870544267     PISSN: 15230864     EISSN: 15577716     Source Type: Journal    
DOI: 10.1089/ars.2011.4373     Document Type: Article

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