p53 regulates oxidative stress-mediated retrograde signaling: A novel mechanism for chemotherapy-induced cardiac injury

PLoS ONE

Volumn 6, Issue 3, 2011, Pages

  Velez, Joyce M ^a   Miriyala, Sumitra ^a   Nithipongvanitch, Ramaneeya ^d   Noel, Teresa ^a   Plabplueng, Chotiros D ^d   Oberley, Terry ^b,c   Jungsuwadee, Paiboon ^a   van Remmen, Holly ^e   Vore, Mary ^a   St Clair, Daret K ^a  

^a UNIVERSITY OF KENTUCKY   (United States)

^b UNIVERSITY OF WISCONSIN SCHOOL OF MEDICINE AND PUBLIC HEALTH   (United States)

^c WILLIAM S MIDDLETON MEMORIAL VETERANS HOSPITAL   (United States)

^d MAHIDOL UNIVERSITY   (Thailand)

^e Mays Cancer Center at UT Health San Antonio   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4 HYDROXYNONENAL; BECLIN; CELL PROTEIN; DOXORUBICIN; GAMMA HISTONE H2AX; HISTONE H2AX; PROTEIN BCL 2; PROTEIN P53; STRESS ACTIVATED PROTEIN KINASE; UNCLASSIFIED DRUG; 4-HYDROXY-2-NONENAL; ALDEHYDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTOPHAGY; CANCER CHEMOTHERAPY; CARDIOTOXICITY; CELL DEATH; CELL NUCLEUS; CONTROLLED STUDY; DISORDERS OF MITOCHONDRIAL FUNCTIONS; DISSOCIATION; DNA DAMAGE; ENZYME ACTIVATION; HEART FUNCTION; HEART LEFT VENTRICLE EJECTION FRACTION; HEART MITOCHONDRION; HISTOPATHOLOGY; HOMOZYGOTE; IMMUNOGOLD STAINING; IMMUNOPRECIPITATION; KNOCKOUT MOUSE; LIPID PEROXIDATION; MALE; MOLECULAR INTERACTION; MOUSE; NONHUMAN; OXIDATIVE STRESS; PATHOPHYSIOLOGY; PROTEIN ANALYSIS; PROTEIN FUNCTION; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; SINGLE DRUG DOSE; WILD TYPE; ANIMAL; BIOLOGICAL MODEL; DRUG EFFECT; ENZYMOLOGY; HEART MUSCLE; METABOLISM; MITOCHONDRION; PATHOLOGY; PHOSPHORYLATION; PHYSIOLOGICAL STRESS; ULTRASTRUCTURE;

MUS;

ALDEHYDES; ANIMALS; AUTOPHAGY; DOXORUBICIN; ENZYME ACTIVATION; JNK MITOGEN-ACTIVATED PROTEIN KINASES; MICE; MITOCHONDRIA; MODELS, BIOLOGICAL; MYOCARDIUM; OXIDATIVE STRESS; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-BCL-2; SIGNAL TRANSDUCTION; STRESS, PHYSIOLOGICAL; TUMOR SUPPRESSOR PROTEIN P53;

EID: 79953299345     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0018005     Document Type: Article

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