Kinetic insulation as an effective mechanism for achieving pathway specificity in intracellular signaling networks

Proceedings of the National Academy of Sciences of the United States of America

Volumn 104, Issue 41, 2007, Pages 16146-16151

  Behar, Marcelo ^a,c   Dohlman, Henrik G ^b   Elston, Timothy C ^b  

^a University of North Carolina at Chapel Hill   (United States)

^b UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF NORTH CAROLINA   (United States)

Author keywords

Adaptive systems; Computational modeling; Cross talk; Filters; Signal transduction

Indexed keywords

ARTICLE; CELL COMMUNICATION; FILTER; KINETICS; MODEL; MOLECULAR MODEL; PRIORITY JOURNAL; SIGNAL PROCESSING; SIGNAL TRANSDUCTION;

BIOPHYSICS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; KINETICS; MAP KINASE SIGNALING SYSTEM; MODELS, BIOLOGICAL; SIGNAL TRANSDUCTION;

EID: 36048944020     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0703894104     Document Type: Article

References (29)

1. Schwartz MA, Madhani HD (2004) Annu Rev Genet 38:725-748.
2. Dohlman HG (2002) Annu Rev Physiol 64:129-152.
3. Muller R (2004) J Cancer Res Clin Oncol 130:429-444.
4. Shi W, Harris AL (2006) J Mammary Gland Biol Neoplasia 11:41-52.
5. Kalaitzidis D, Gilmore TD (2005) Trends Endocrinol Metab 16:46-52.
6. Bardwell L (2006) Biochem Soc Trans 34:837-841.
7. Kolch W (2005) Nat Rev Mol Cell Biol 6:827-837.
8. Flatauer LJ, Zadeh SF, Bardwell L (2005) Mol Cell Biol 25:1793-1803.
9. Dard N, Peter M (2006) BioEssays 28:146-156.
10. Chou S, Huang L, Liu H (2004) Cell 119:981-990.
11. Sacks DB (2006) Biochem Soc Trans 34:833-836.
12. Vandecasteele G, Rochais F, Abi-Gerges A, Fischmeister R (2006) Biochem Soc Trans 34:484-488.
13. Komarova NL, Zou X, Nie Q, Bardwell L (2005) Mol Syst Biol 1:2005.0023.
14. Bardwell L, Zou X, Nie Q, Komarova NL (2007) Biophys J 92:3425-3441.
15. Schaber J, Kofahl B, Kowald A, Klipp E (2006) FEBS J 273:3520-3533.
16. Somsen OJ, Siderius M, Bauer FF, Snoep JL, Westerhoff HV (2002) J Theor Biol 218:343-354.
17. Klipp E, Nordlander B, Kruger R, Gennemark P, Hohmann S (2005) Nat Biotechnol 23:975-982.
18. Alon U (2007) An Introduction to Systems Biology: Design Principles of Biological Circuits (Chapman & Hall/CRC, London).
19. Behar M, Hao N, Dohlman HG, Elston TC (2007) Biophys J 93:806-821.
20. Goldbeter A, Koshland DE, Jr (1981) Proc Natl Acad Sci USA 78:6840-6844.
21. McClean MN, Mody A, Broach JR, Ramanathan S (2007) Nat Genet 39:409-414.
22. Erdman S, Snyder M (2001) Genetics 159:919-928.
23. Huang CY, Ferrell JE, Jr (1996) Proc Natl Acad Sci USA 93:10078-10083.
24. Heinrich R, Neel BG, Rapoport TA (2002) Mol Cell 9:957-970.
25. Hao N, Behar M, Parnell SC, Torres MP, Borchers CH, Elston TC, Dohlman HG (2007) Curr Biol 17:659-667.
26. O'Rourke SM, Herskowitz I (1998) Genes Dev 12:2874-2886.
27. O'Rourke SM, Herskowitz I (2004) Mol Biol Cell 15:532-542.
28. Gacto M, Soto T, Vicente-Soler J, Villa TG, Cansado J (2003) Int Microbiol 6:211-219.
29. Hohmann S (2002) Microbiol Mol Biol Rev 66:300-372.