-
1
-
-
47249131603
-
Innate immunity mediated by TLR5 as a novel antiinflammatory target for cystic fibrosis lung disease
-
Blohmke CJ, Victor RE, Hirschfeld AF, Elias IM, Hancock DG, Lane CR, Davidson AG, Wilcox PG, Smith KD, Overhage J, Hancock RE, Turvey SE. 2008. Innate immunity mediated by TLR5 as a novel antiinflammatory target for cystic fibrosis lung disease. J Immunol 180(11):7764-7773.
-
(2008)
J Immunol
, vol.180
, Issue.11
, pp. 7764-7773
-
-
Blohmke, C.J.1
Victor, R.E.2
Hirschfeld, A.F.3
Elias, I.M.4
Hancock, D.G.5
Lane, C.R.6
Davidson, A.G.7
Wilcox, P.G.8
Smith, K.D.9
Overhage, J.10
Hancock, R.E.11
Turvey, S.E.12
-
2
-
-
42049095095
-
An agonist of toll-like receptor 5 has radioprotective activity in mouse and primate models
-
DOI 10.1126/science.1154986
-
Burdelya LG, Krivokrysenko VI, Tallant TC, Strom E, Gleiberman AS, Gupta D, Kurnasov OV, Fort FL, Osterman AL, Didonato JA, Feinstein E, Gudkov AV. 2008. An agonist of toll-like receptor 5 has radioprotective activity in mouse and primate models. Science 320(5873):226-230. (Pubitemid 351521417)
-
(2008)
Science
, vol.320
, Issue.5873
, pp. 226-230
-
-
Burdelya, L.G.1
Krivokrysenko, V.I.2
Tallant, T.C.3
Strom, E.4
Gleiberman, A.S.5
Gupta, D.6
Kurnasov, O.V.7
Fort, F.L.8
Osterman, A.L.9
DiDonato, J.A.10
Feinstein, E.11
Gudkov, A.V.12
-
3
-
-
49749149169
-
Crohn's disease-associated Escherichia coli LF82 aggravates colitis in injured mouse colon via signaling by flagellin
-
Carvalho FA, Barnich N, Sauvanet P, Darcha C, Gelot A, Darfeuille- Michaud A. 2008. Crohn's disease-associated Escherichia coli LF82 aggravates colitis in injured mouse colon via signaling by flagellin. Inflamm Bowel Dis 14(8):1051-1060.
-
(2008)
Inflamm Bowel Dis
, vol.14
, Issue.8
, pp. 1051-1060
-
-
Carvalho, F.A.1
Barnich, N.2
Sauvanet, P.3
Darcha, C.4
Gelot, A.5
Darfeuille-Michaud, A.6
-
4
-
-
78549284013
-
TRIF Mediates Toll-like Receptor 5-induced Signaling in Intestinal Epithelial Cells
-
Choi YJ, Im E, Chung HK, Pothoulakis C, Rhee SH. 2010a. TRIF Mediates Toll-like Receptor 5-induced Signaling in Intestinal Epithelial Cells. J Biol Chem 285(48):37570-37578.
-
(2010)
J Biol Chem
, vol.285
, Issue.48
, pp. 37570-37578
-
-
Choi, Y.J.1
Im, E.2
Chung, H.K.3
Pothoulakis, C.4
Rhee, S.H.5
-
5
-
-
77954381441
-
TRIF modulates TLR5-dependent responses by inducing proteolytic degradation of TLR5
-
Choi YJ, Im E, Pothoulakis C, Rhee SH. 2010b. TRIF modulates TLR5-dependent responses by inducing proteolytic degradation of TLR5. J Biol Chem 285(28):21382-21390.
-
(2010)
J Biol Chem
, vol.285
, Issue.28
, pp. 21382-21390
-
-
Choi, Y.J.1
Im, E.2
Pothoulakis, C.3
Rhee, S.H.4
-
6
-
-
76949085276
-
Identification of the early VIP-regulated transcriptome and its associated, interactome in resting and activated murine CD4 T cells
-
Dorsam ST, Vomhof-Dekrey E, Hermann RJ, Haring JS, Van der Steen T, Wilkerson E, Boskovic G, Denvir J, Dementieva Y, Primerano D, Dorsam GP. 2010. Identification of the early VIP-regulated transcriptome and its associated, interactome in resting and activated murine CD4 T cells. Mol Immunol 47(6):1181-1194.
-
(2010)
Mol Immunol
, vol.47
, Issue.6
, pp. 1181-1194
-
-
Dorsam, S.T.1
Vomhof-Dekrey, E.2
Hermann, R.J.3
Haring, J.S.4
Van Der Steen, T.5
Wilkerson, E.6
Boskovic, G.7
Denvir, J.8
Dementieva, Y.9
Primerano, D.10
Dorsam, G.P.11
-
7
-
-
33747769371
-
Involvement of toll-like receptor 5 in the recognition of flagellated bacteria
-
DOI 10.1073/pnas.0605200103
-
Feuillet V, Medjane S, Mondor I, Demaria O, Pagni PP, Galan JE, Flavell RA, Alexopoulou L. 2006. Involvement of Toll-like receptor 5 in the recognition of flagellated bacteria. Proc Natl Acad Sci U S A 103(33):12487-12492. (Pubitemid 44274883)
-
(2006)
Proceedings of the National Academy of Sciences of the United States of America
, vol.103
, Issue.33
, pp. 12487-12492
-
-
Feuillet, V.1
Medjane, S.2
Mondor, I.3
Demaria, O.4
Pagni, P.P.5
Galan, J.E.6
Flavell, R.A.7
Alexopoulou, L.8
-
8
-
-
33744464740
-
Cytosolic flagellin requires Ipaf for activation of caspase-1 and interleukin 1β in salmonella-infected macrophages
-
DOI 10.1038/ni1346, PII N1346
-
Franchi L, Amer A, Body-Malapel M, Kanneganti TD, Ozoren N, Jagirdar R, Inohara N, Vandenabeele P, Bertin J, Coyle A, Grant EP, Nunez G. 2006. Cytosolic flagellin requires Ipaf for activation of caspase-1 and interleukin 1beta in salmonellainfected macrophages. Nat Immunol 7(6):576-582. (Pubitemid 43797338)
-
(2006)
Nature Immunology
, vol.7
, Issue.6
, pp. 576-582
-
-
Franchi, L.1
Amer, A.2
Body-Malapel, M.3
Kanneganti, T.-D.4
Ozoren, N.5
Jagirdar, R.6
Inohara, N.7
Vandenabeele, P.8
Bertin, J.9
Coyle, A.10
Grant, E.P.11
Nunez, G.12
-
9
-
-
0037216498
-
Increased expression of interleukin 17 in inflammatory bowel disease
-
DOI 10.1136/gut.52.1.65
-
Fujino S, Andoh A, Bamba S, Ogawa A, Hata K, Araki Y, Bamba T, Fujiyama Y. 2003. Increased expression of interleukin 17 in inflammatory bowel disease. Gut 52(1):65-70. (Pubitemid 36020767)
-
(2003)
Gut
, vol.52
, Issue.1
, pp. 65-70
-
-
Fujino, S.1
Andoh, A.2
Bamba, S.3
Ogawa, A.4
Hata, K.5
Araki, Y.6
Bamba, T.7
Fujiyama, Y.8
-
10
-
-
80053600391
-
Recent advances in the IL-17 cytokine family
-
Gaffen SL. 2011. Recent advances in the IL-17 cytokine family. Curr Opin Immunol 23(5):613-619.
-
(2011)
Curr Opin Immunol
, vol.23
, Issue.5
, pp. 613-619
-
-
Gaffen, S.L.1
-
11
-
-
77950535421
-
LY2439821, a humanized anti-interleukin-17 monoclonal antibody, in the treatment of patients with rheumatoid arthritis: A phase i randomized, double-blind, placebo-controlled, proof-of-concept study
-
Genovese MC, Van den Bosch F, Roberson SA, Bojin S, Biagini IM, Ryan P, Sloan-Lancaster J. 2010. LY2439821, a humanized anti-interleukin-17 monoclonal antibody, in the treatment of patients with rheumatoid arthritis: a phase I randomized, double-blind, placebo-controlled, proof-of-concept study. Arthritis Rheum 62(4):929-939.
-
(2010)
Arthritis Rheum
, vol.62
, Issue.4
, pp. 929-939
-
-
Genovese, M.C.1
Van Den Bosch, F.2
Roberson, S.A.3
Bojin, S.4
Biagini, I.M.5
Ryan, P.6
Sloan-Lancaster, J.7
-
12
-
-
33646866567
-
Dominant-negative TLR5 polymorphism reduces adaptive immune response to flagellin and negatively associates with Crohn's disease
-
DOI 10.1152/ajpgi.00544.2005
-
Gewirtz AT, Vijay-Kumar M, Brant SR, Duerr RH, Nicolae DL, Cho JH. 2006. Dominant-negative TLR5 polymorphism reduces adaptive immune response to flagellin and negatively associates with Crohn's disease. Am J Physiol Gastrointest Liver Physiol 290(6):G1157-G1163. (Pubitemid 43788297)
-
(2006)
American Journal of Physiology - Gastrointestinal and Liver Physiology
, vol.290
, Issue.6
-
-
Gewirtz, A.T.1
Vijay-Kumar, M.2
Brant, S.R.3
Duerr, R.H.4
Nicolae, D.L.5
Cho, J.H.6
-
13
-
-
3242814586
-
Requirement of interleukin-17A for systemic anti-Candida albicans host defense in mice
-
DOI 10.1086/422329
-
Huang W, Na L, Fidel PL, Schwarzenberger P. 2004. Requirement of interleukin-17A for systemic anti-Candida albicans host defense in mice. J Infect Dis 190(3):624-631. (Pubitemid 38982105)
-
(2004)
Journal of Infectious Diseases
, vol.190
, Issue.3
, pp. 624-631
-
-
Huang, W.1
Na, L.2
Fidel, P.L.3
Schwarzenberger, P.4
-
14
-
-
77958072084
-
Effects of AIN457, a fully human antibody to interleukin- 17A, on psoriasis, rheumatoid arthritis, and uveitis
-
Hueber W, Patel DD, Dryja T, Wright AM, Koroleva I, Bruin G, Antoni C, Draelos Z, Gold MH, Durez P, Tak PP, Gomez- Reino JJ, Foster CS, Kim RY, Samson CM, Falk NS, Chu DS, Callanan D, Nguyen QD, Rose K, Haider A, Di Padova F. 2010. Effects of AIN457, a fully human antibody to interleukin- 17A, on psoriasis, rheumatoid arthritis, and uveitis. Sci Transl Med 2(52):52ra72.
-
(2010)
Sci Transl Med
, vol.2
, Issue.52
-
-
Hueber, W.1
Patel, D.D.2
Dryja, T.3
Wright, A.M.4
Koroleva, I.5
Bruin, G.6
Antoni, C.7
Draelos, Z.8
Gold, M.H.9
Durez, P.10
Tak, P.P.11
Gomez- Reino, J.J.12
Foster, C.S.13
Kim, R.Y.14
Samson, C.M.15
Falk, N.S.16
Chu, D.S.17
Callanan, D.18
Nguyen, Q.D.19
Rose, K.20
Haider, A.21
Di Padova, F.22
more..
-
15
-
-
70349311440
-
Bacillus polyfermenticus ameliorates colonic inflammation by promoting cytoprotective effects in colitic mice
-
Im E, Choi YJ, Pothoulakis C, Rhee SH. 2009. Bacillus polyfermenticus ameliorates colonic inflammation by promoting cytoprotective effects in colitic mice. J Nutr 139(10):1848-1854.
-
(2009)
J Nutr
, vol.139
, Issue.10
, pp. 1848-1854
-
-
Im, E.1
Choi, Y.J.2
Pothoulakis, C.3
Rhee, S.H.4
-
16
-
-
77149142027
-
TLR5 is not required for flagellin- mediated exacerbation of DSS colitis
-
Ivison SM, Himmel ME, Hardenberg G, Wark PA, Kifayet A, Levings MK, Steiner TS. 2010. TLR5 is not required for flagellin- mediated exacerbation of DSS colitis. Inflamm Bowel Dis 16(3):401-409.
-
(2010)
Inflamm Bowel Dis
, vol.16
, Issue.3
, pp. 401-409
-
-
Ivison, S.M.1
Himmel, M.E.2
Hardenberg, G.3
Wark, P.A.4
Kifayet, A.5
Levings, M.K.6
Steiner, T.S.7
-
17
-
-
47249161701
-
Requirements for two proximal NF-kappaB binding sites and IkappaB-zeta in IL- 17A-induced human beta-defensin 2 expression by conducting airway epithelium
-
Kao CY, Kim C, Huang F, Wu R. 2008. Requirements for two proximal NF-kappaB binding sites and IkappaB-zeta in IL- 17A-induced human beta-defensin 2 expression by conducting airway epithelium. J Biol Chem 283(22):15309-15318.
-
(2008)
J Biol Chem
, vol.283
, Issue.22
, pp. 15309-15318
-
-
Kao, C.Y.1
Kim, C.2
Huang, F.3
Wu, R.4
-
18
-
-
0030969765
-
A protein-tyrosine kinase-regulated, pH-dependent, carrier-mediated uptake system for folate in human normal colonic epithelial cell line NCM460
-
DOI 10.1074/jbc.272.10.6226
-
Kumar CK, Moyer MP, Dudeja PK, Said HM. 1997. A proteintyrosine kinase-regulated, pH-dependent, carrier-mediated uptake system for folate in human normal colonic epithelial cell line NCM460. J Biol Chem 272(10):6226-6231. (Pubitemid 27118093)
-
(1997)
Journal of Biological Chemistry
, vol.272
, Issue.10
, pp. 6226-6231
-
-
Kumar, C.K.1
Moyer, M.P.2
Dudeja, P.K.3
Said, H.M.4
-
19
-
-
79955527226
-
TLR5-deficient mice lack basal inflammatory and metabolic defects but exhibit impaired CD4 T cell responses to a flagellated pathogen
-
Letran SE, Lee SJ, Atif SM, Flores-Langarica A, Uematsu S, Akira S, Cunningham AF, McSorley SJ. 2011. TLR5-deficient mice lack basal inflammatory and metabolic defects but exhibit impaired CD4 T cell responses to a flagellated pathogen. J Immunol 186(9):5406-5412.
-
(2011)
J Immunol
, vol.186
, Issue.9
, pp. 5406-5412
-
-
Letran, S.E.1
Lee, S.J.2
Atif, S.M.3
Flores-Langarica, A.4
Uematsu, S.5
Akira, S.6
Cunningham, A.F.7
McSorley, S.J.8
-
21
-
-
33644696706
-
Distinct mechanisms of glucose lowering by specific agonists for peroxisomal proliferator activated receptor γ and retinoic acid X receptors
-
DOI 10.1074/jbc.M505853200
-
Li X, Hansen PA, Xi L, Chandraratna RA, Burant CF. 2005. Distinct mechanisms of glucose lowering by specific agonists for peroxisomal proliferator activated receptor gamma and retinoic acid X receptors. J Biol Chem 280(46):38317-38327. (Pubitemid 43860306)
-
(2005)
Journal of Biological Chemistry
, vol.280
, Issue.46
, pp. 38317-38327
-
-
Li, X.1
Hansen, P.A.2
Xi, L.3
Chandraratna, R.A.S.4
Burant, C.F.5
-
22
-
-
2342646956
-
Bacterial flagellin is a dominant antigen in Crohn disease
-
DOI 10.1172/JCI200420295
-
Lodes MJ, Cong Y, Elson CO, Mohamath R, Landers CJ, Targan SR, Fort M, Hershberg RM. 2004. Bacterial flagellin is a dominant antigen in Crohn disease. J Clin Invest 113(9):1296-1306. (Pubitemid 39069929)
-
(2004)
Journal of Clinical Investigation
, vol.113
, Issue.9
, pp. 1296-1306
-
-
Lodes, M.J.1
Cong, Y.2
Elson, C.O.3
Mohamath, R.4
Landers, C.J.5
Targan, S.R.6
Fort, M.7
Hershberg, R.M.8
-
23
-
-
34548679608
-
TLR5 and Ipaf: Dual sensors of bacterial flagellin in the innate immune system
-
DOI 10.1007/s00281-007-0078-z, The NLR-related Disorders
-
Miao EA, Andersen-Nissen E, Warren SE, Aderem A. 2007. TLR5 and Ipaf: dual sensors of bacterial flagellin in the innate immune system. Semin Immunopathol 29(3):275-288. (Pubitemid 47416216)
-
(2007)
Seminars in Immunopathology
, vol.29
, Issue.3
, pp. 275-288
-
-
Miao, E.A.1
Andersen-Nissen, E.2
Warren, S.E.3
Aderem, A.4
-
24
-
-
0030158341
-
NCM460, a normal human colon mucosal epithelial cell line
-
Moyer MP, Manzano LA, Merriman RL, Stauffer JS, Tanzer LR. 1996. NCM460, a normal human colon mucosal epithelial cell line. In Vitro Cell Dev Biol Anim 32(6):315-317.
-
(1996)
Vitro Cell Dev Biol Anim
, vol.32
, Issue.6
, pp. 315-317
-
-
Moyer, M.P.1
Manzano, L.A.2
Merriman, R.L.3
Stauffer, J.S.4
Tanzer, L.R.5
-
25
-
-
79961210510
-
The interleukin- 17 cytokine family: Critical players in host defence and inflammatory diseases
-
Pappu R, Ramirez-Carrozzi V, Sambandam A. 2011. The interleukin- 17 cytokine family: critical players in host defence and inflammatory diseases. Immunology 134(1):8-16.
-
(2011)
Immunology
, vol.134
, Issue.1
, pp. 8-16
-
-
Pappu, R.1
Ramirez-Carrozzi, V.2
Sambandam, A.3
-
26
-
-
58849143880
-
IL-17A enhances vitamin D3-induced expression of cathelicidin antimicrobial peptide in human keratinocytes
-
Peric M, Koglin S, Kim SM, Morizane S, Besch R, Prinz JC, Ruzicka T, Gallo RL, Schauber J. 2008. IL-17A enhances vitamin D3-induced expression of cathelicidin antimicrobial peptide in human keratinocytes. J Immunol 181(12):8504-8512.
-
(2008)
J Immunol
, vol.181
, Issue.12
, pp. 8504-8512
-
-
Peric, M.1
Koglin, S.2
Kim, S.M.3
Morizane, S.4
Besch, R.5
Prinz, J.C.6
Ruzicka, T.7
Gallo, R.L.8
Schauber, J.9
-
27
-
-
79953284685
-
Chronic mucocutaneous candidiasis in humans with inborn errors of interleukin-17 immunity
-
Puel A, Cypowyj S, Bustamante J, Wright JF, Liu L, Lim HK, Migaud M, Israel L, Chrabieh M, Audry M, Gumbleton M, Toulon A, Bodemer C, El-Baghdadi J, Whitters M, Paradis T, Brooks J, Collins M, Wolfman NM, Al-Muhsen S, Galicchio M, Abel L, Picard C, Casanova JL. 2011. Chronic mucocutaneous candidiasis in humans with inborn errors of interleukin-17 immunity. Science 332(6025):65-68.
-
(2011)
Science
, vol.332
, Issue.6025
, pp. 65-68
-
-
Puel, A.1
Cypowyj, S.2
Bustamante, J.3
Wright, J.F.4
Liu, L.5
Lim, H.K.6
Migaud, M.7
Israel, L.8
Chrabieh, M.9
Audry, M.10
Gumbleton, M.11
Toulon, A.12
Bodemer, C.13
El-Baghdadi, J.14
Whitters, M.15
Paradis, T.16
Brooks, J.17
Collins, M.18
Wolfman, N.M.19
Al-Muhsen, S.20
Galicchio, M.21
Abel, L.22
Picard, C.23
Casanova, J.L.24
more..
-
28
-
-
81255158784
-
IL-17C regulates the innate immune function of epithelial cells in an autocrine manner
-
Ramirez-Carrozzi V, Sambandam A, Luis E, Lin Z, Jeet S, Lesch J, Hackney J, Kim J, Zhou M, Lai J, Modrusan Z, Sai T, Lee W, Xu M, Caplazi P, Diehl L, de Voss J, Balazs M, Gonzalez L, Jr., Singh H, Ouyang W, Pappu R. 2011. IL-17C regulates the innate immune function of epithelial cells in an autocrine manner. Nat Immunol 12(12):1159-1166.
-
(2011)
Nat Immunol
, vol.12
, Issue.12
, pp. 1159-1166
-
-
Ramirez-Carrozzi, V.1
Sambandam, A.2
Luis, E.3
Lin, Z.4
Jeet, S.5
Lesch, J.6
Hackney, J.7
Kim, J.8
Zhou, M.9
Lai, J.10
Modrusan, Z.11
Sai, T.12
Lee, W.13
Xu, M.14
Caplazi, P.15
Diehl, L.16
De Voss, J.17
Balazs, M.18
Gonzalez Jr., L.19
Singh, H.20
Ouyang, W.21
Pappu, R.22
more..
-
30
-
-
48549106083
-
Toll-like receptor 5 engagement modulates tumor development and growth in a mouse xenograft model of human colon cancer
-
Rhee SH, Im E, Pothoulakis C. 2008. Toll-like receptor 5 engagement modulates tumor development and growth in a mouse xenograft model of human colon cancer. Gastroenterology 135(2):518-528.
-
(2008)
Gastroenterology
, vol.135
, Issue.2
, pp. 518-528
-
-
Rhee, S.H.1
Im, E.2
Pothoulakis, C.3
-
31
-
-
26444440067
-
Pathophysiological role of Toll-like receptor 5 engagement by bacterial flagenllin in colonic inflammation
-
DOI 10.1073/pnas.0502174102
-
Rhee SH, Im E, Riegler M, Kokkotou E, O'Brien M, Pothoulakis C. 2005. Pathophysiological role of Toll-like receptor 5 engagement by bacterial flagellin in colonic inflammation. Proc Natl Acad Sci U S A 102(38):13610-13615. (Pubitemid 41420896)
-
(2005)
Proceedings of the National Academy of Sciences of the United States of America
, vol.102
, Issue.38
, pp. 13610-13615
-
-
Rhee, S.H.1
Im, E.2
Riegler, M.3
Kokkotou, E.4
O'Brien, M.5
Pothoulakis, C.6
-
32
-
-
2942560322
-
MEK is a key modulator for TLR5-induced interleukin-8 and MIP3α gene expression in non-transformed human colonic epithelial cells
-
DOI 10.1074/jbc.M400967200
-
Rhee SH, Keates AC, Moyer MP, Pothoulakis C. 2004. MEK is a key modulator for TLR5-induced interleukin-8 and MIP3alpha gene expression in non-transformed human colonic epithelial cells. J Biol Chem 279(24):25179-25188. (Pubitemid 38756768)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.24
, pp. 25179-25188
-
-
Rhee, S.H.1
Keates, A.C.2
Moyer, M.P.3
Pothoulakis, C.4
-
33
-
-
33745868678
-
Role of MyD88 in phosphatidylinositol 3-kinase activation by flagellin/toll-like receptor 5 engagement in colonic epithelial cells
-
DOI 10.1074/jbc.M513861200
-
Rhee SH, Kim H, Moyer MP, Pothoulakis C. 2006. Role of MyD88 in phosphatidylinositol 3-kinase activation by flagellin/ toll-like receptor 5 engagement in colonic epithelial cells. J Biol Chem 281(27):18560-18568. (Pubitemid 44035515)
-
(2006)
Journal of Biological Chemistry
, vol.281
, Issue.27
, pp. 18560-18568
-
-
Sang, H.R.1
Kim, H.2
Moyer, M.P.3
Pothoulakis, C.4
-
34
-
-
0025152051
-
P53 mutations in colorectal cancer
-
Rodrigues NR, Rowan A, Smith ME, Kerr IB, Bodmer WF, Gannon JV, Lane DP. 1990. p53 mutations in colorectal cancer. Proc Natl Acad Sci U S A 87(19):7555-7559. (Pubitemid 20341755)
-
(1990)
Proceedings of the National Academy of Sciences of the United States of America
, vol.87
, Issue.19
, pp. 7555-7559
-
-
Rodrigues, N.R.1
Rowan, A.2
Smith, M.E.F.3
Kerr, I.B.4
Bodmer, W.F.5
Gannon, J.V.6
Lane, D.P.7
-
35
-
-
0034724186
-
APC mutations in sporadic colorectal tumors: A mutational 'hotspot' and interdependence of the 'two hits'
-
DOI 10.1073/pnas.97.7.3352
-
Rowan AJ, Lamlum H, Ilyas M, Wheeler J, Straub J, Papadopoulou A, Bicknell D, Bodmer WF, Tomlinson IP. 2000. APC mutations in sporadic colorectal tumors: A mutational "hotspot" and interdependence of the "two hits". Proc Natl Acad Sci U S A 97(7):3352-3357. (Pubitemid 30183306)
-
(2000)
Proceedings of the National Academy of Sciences of the United States of America
, vol.97
, Issue.7
, pp. 3352-3357
-
-
Rowan, A.J.1
Lamlum, H.2
Ilyas, M.3
Wheeler, J.4
Straub, J.5
Papadopoulou, A.6
Bicknell, D.7
Bodmer, W.F.8
Tomlinson, I.P.M.9
-
36
-
-
77953289487
-
Dectin-2 recognition of alpha-mannans and induction of Th17 cell differentiation is essential for host defense against Candida albicans
-
Saijo S, Ikeda S, Yamabe K, Kakuta S, Ishigame H, Akitsu A, Fujikado N, Kusaka T, Kubo S, Chung SH, Komatsu R, Miura N, Adachi Y, Ohno N, Shibuya K, Yamamoto N, Kawakami K, Yamasaki S, Saito T, Akira S, Iwakura Y. 2010. Dectin-2 recognition of alpha-mannans and induction of Th17 cell differentiation is essential for host defense against Candida albicans. Immunity 32(5):681-691.
-
(2010)
Immunity
, vol.32
, Issue.5
, pp. 681-691
-
-
Saijo, S.1
Ikeda, S.2
Yamabe, K.3
Kakuta, S.4
Ishigame, H.5
Akitsu, A.6
Fujikado, N.7
Kusaka, T.8
Kubo, S.9
Chung, S.H.10
Komatsu, R.11
Miura, N.12
Adachi, Y.13
Ohno, N.14
Shibuya, K.15
Yamamoto, N.16
Kawakami, K.17
Yamasaki, S.18
Saito, T.19
Akira, S.20
Iwakura, Y.21
more..
-
37
-
-
3042789092
-
Toll-like receptor (TLR) expression and TLR-mediated cytokine/chemokine production by human uterine epithelial cells
-
DOI 10.1111/j.1365-2567.2004.01898.x
-
Schaefer TM, Desouza K, Fahey JV, Beagley KW, Wira CR. 2004. Toll-like receptor (TLR) expression and TLR-mediated cytokine/ chemokine production by human uterine epithelial cells. Immunology 112(3):428-436. (Pubitemid 38859521)
-
(2004)
Immunology
, vol.112
, Issue.3
, pp. 428-436
-
-
Schaefer, T.M.1
Desouza, K.2
Fahey, J.V.3
Beagley, K.W.4
Wira, C.R.5
-
38
-
-
42449084096
-
Role of the novel Th17 cytokine IL-17F in inflammatory bowel disease (IBD): Upregulated colonic IL-17F expression in active Crohn's disease and analysis of the IL17F p.His161Arg polymorphism in IBD
-
DOI 10.1002/ibd.20339
-
Seiderer J, Elben I, Diegelmann J, Glas J, Stallhofer J, Tillack C, Pfennig S, Jurgens M, Schmechel S, Konrad A, Goke B, Ochsenkuhn T, Muller-Myhsok B, Lohse P, Brand S. 2008. Role of the novel Th17 cytokine IL-17F in inflammatory bowel disease (IBD): upregulated colonic IL-17F expression in active Crohn's disease and analysis of the IL17F p.His161Arg polymorphism in IBD. Inflamm Bowel Dis 14(4):437-445. (Pubitemid 351571823)
-
(2008)
Inflammatory Bowel Diseases
, vol.14
, Issue.4
, pp. 437-445
-
-
Seiderer, J.1
Elben, I.2
Diegelmann, J.3
Glas, J.4
Stallhofer, J.5
Tillack, C.6
Pfennig, S.7
Jurgens, M.8
Schmechel, S.9
Konrad, A.10
Goke, B.11
Ochsenkuhn, T.12
Muller-Myhsok, B.13
Lohse, P.14
Brand, S.15
-
39
-
-
12344309055
-
Elevated flagellin-specific immunoglobulins in Crohn's disease
-
DOI 10.1152/ajpgi.00357.2004
-
Sitaraman SV, Klapproth JM, Moore DA, 3rd, Landers C, Targan S, Williams IR, Gewirtz AT. 2005. Elevated flagellin-specific immunoglobulins in Crohn's disease. Am J Physiol Gastrointest Liver Physiol 288(2):G403-G406. (Pubitemid 40129593)
-
(2005)
American Journal of Physiology - Gastrointestinal and Liver Physiology
, vol.288
, Issue.2
-
-
Sitaraman, S.V.1
Klapproth, J.-M.2
Moore III, D.A.3
Landers, C.4
Targan, S.5
Williams, I.R.6
Gewirtz, A.T.7
-
40
-
-
81255158786
-
IL- 17RE is the functional receptor for IL-17C and mediates mucosal immunity to infection with intestinal pathogens
-
Song X, Zhu S, Shi P, Liu Y, Shi Y, Levin SD, Qian Y. 2011. IL- 17RE is the functional receptor for IL-17C and mediates mucosal immunity to infection with intestinal pathogens. Nat Immunol 12(12):1151-1158.
-
(2011)
Nat Immunol
, vol.12
, Issue.12
, pp. 1151-1158
-
-
Song, X.1
Zhu, S.2
Shi, P.3
Liu, Y.4
Shi, Y.5
Levin, S.D.6
Qian, Y.7
-
41
-
-
20444441016
-
Antibodies to CBir1 flagellin define a unique response that is associated independently with complicated Crohn's disease
-
DOI 10.1053/j.gastro.2005.03.046, PII S001650850500569X
-
Targan SR, Landers CJ, Yang H, Lodes MJ, Cong Y, Papadakis KA, Vasiliauskas E, Elson CO, Hershberg RM. 2005. Antibodies to CBir1 flagellin define a unique response that is associated independently with complicated Crohn's disease. Gastroenterology 128(7):2020-2028. (Pubitemid 40824710)
-
(2005)
Gastroenterology
, vol.128
, Issue.7
, pp. 2020-2028
-
-
Targan, S.R.1
Landers, C.J.2
Yang, H.3
Lodes, M.J.4
Cong, Y.5
Papadakis, K.A.6
Vasiliauskas, E.7
Elson, C.O.8
Hershberg, R.M.9
-
42
-
-
77950250064
-
Metabolic syndrome and altered gut microbiota in mice lacking Toll-like receptor 5
-
Vijay-Kumar M, Aitken JD, Carvalho FA, Cullender TC, Mwangi S, Srinivasan S, Sitaraman SV, Knight R, Ley RE, Gewirtz AT. 2010. Metabolic syndrome and altered gut microbiota in mice lacking Toll-like receptor 5. Science 328(5975): 228-231.
-
(2010)
Science
, vol.328
, Issue.5975
, pp. 228-231
-
-
Vijay-Kumar, M.1
Aitken, J.D.2
Carvalho, F.A.3
Cullender, T.C.4
Mwangi, S.5
Srinivasan, S.6
Sitaraman, S.V.7
Knight, R.8
Ley, R.E.9
Gewirtz, A.T.10
-
43
-
-
48549085489
-
Flagellin treatment protects against chemicals, bacteria, viruses, and radiation
-
Vijay-Kumar M, Aitken JD, Sanders CJ, Frias A, Sloane VM, Xu J, Neish AS, Rojas M, Gewirtz AT. 2008. Flagellin treatment protects against chemicals, bacteria, viruses, and radiation. J Immunol 180(12):8280-8285.
-
(2008)
J Immunol
, vol.180
, Issue.12
, pp. 8280-8285
-
-
Vijay-Kumar, M.1
Aitken, J.D.2
Sanders, C.J.3
Frias, A.4
Sloane, V.M.5
Xu, J.6
Neish, A.S.7
Rojas, M.8
Gewirtz, A.T.9
-
44
-
-
36849000520
-
Deletion of TLR5 results in spontaneous colitis in mice
-
DOI 10.1172/JCI33084
-
Vijay-Kumar M, Sanders CJ, Taylor RT, Kumar A, Aitken JD, Sitaraman SV, Neish AS, Uematsu S, Akira S, Williams IR, Gewirtz AT. 2007. Deletion of TLR5 results in spontaneous colitis in mice. J Clin Invest 117(12):3909-3921. (Pubitemid 350224100)
-
(2007)
Journal of Clinical Investigation
, vol.117
, Issue.12
, pp. 3909-3921
-
-
Vijay-Kumar, M.1
Sanders, C.J.2
Taylor, R.T.3
Kumar, A.4
Aitken, J.D.5
Sitaraman, S.V.6
Neish, A.S.7
Uematsu, S.8
Akira, S.9
Williams, I.R.10
Gewirtz, A.T.11
-
45
-
-
78651352892
-
High levels of Crohn's disease-associated anti-microbial antibodies are present and independent of colitis in chronic granulomatous disease
-
Yu JE, De Ravin SS, Uzel G, Landers C, Targan S, Malech HL, Holland SM, Cao W, Harpaz N, Mayer L, Cunningham- Rundles C. 2011. High levels of Crohn's disease-associated anti-microbial antibodies are present and independent of colitis in chronic granulomatous disease. Clin Immunol 138(1): 14-22.
-
(2011)
Clin Immunol
, vol.138
, Issue.1
, pp. 14-22
-
-
Yu, J.E.1
De Ravin, S.S.2
Uzel, G.3
Landers, C.4
Targan, S.5
Malech, H.L.6
Holland, S.M.7
Cao, W.8
Harpaz, N.9
Mayer, L.10
Cunningham-Rundles, C.11
|