Gambogic acid promotes apoptosis and resistance to metastatic potential in MDA-MB-231 human breast carcinoma cells

Biochemistry and Cell Biology

Volumn 90, Issue 6, 2012, Pages 718-730

  Li, Chenglin ^a   Qi, Qi ^b   Lu, Na ^a   Dai, Qinsheng ^a   Li, Fanni ^a   Wang, Xiaotang ^c   You, Qidong ^a   Guo, Qinglong ^a  

^a CHINA PHARMACEUTICAL UNIVERSITY   (China)

^b EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c FLORIDA INTERNATIONAL UNIVERSITY   (United States)

Author keywords

Apoptosis; Gambogic acid; Human breast cancer; Metastasis; Multiple effects

Indexed keywords

ANIMAL MODEL; ANTI-TUMOR AGENTS; APOPTOTIC; APOPTOTIC PATHWAYS; ATHYMIC; BREAST CANCER; CANCER CELLS; CASPASE-3; CELL SURVIVAL; CELL VIABILITY; CYTOCHROME C; HUMAN BREAST CANCER; HUMAN BREAST CANCER CELLS; HUMAN BREAST CARCINOMA CELLS; HUMAN CANCER; IN-VITRO; IN-VIVO; INDUCED APOPTOSIS; LOW CONCENTRATIONS; LUNG METASTASIS; METASTASIS; METASTATIC POTENTIAL; MULTIPLE EFFECT; NUDE MICE; POTENTIAL APPLICATIONS; REACTIVE OXYGEN SPECIES; TUMOR GROWTH;

DISEASES; MITOCHONDRIA; PATHOLOGY; TUMORS;

CELL DEATH;

APOPTOSIS INDUCING FACTOR; CASPASE 3; CASPASE 8; CASPASE 9; CYTOCHROME C; DOXORUBICIN; GAMBOGIC ACID; MAMMALIAN TARGET OF RAPAMYCIN; PROTEIN BAX; PROTEIN BCL 2; PROTEIN KINASE B; REACTIVE OXYGEN METABOLITE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BREAST CARCINOMA; CANCER INHIBITION; CARCINOMA CELL; CELL SURVIVAL; CONTROLLED STUDY; FEMALE; HISTOPATHOLOGY; HUMAN; HUMAN CELL; LUNG METASTASIS; METASTASIS; MITOCHONDRION; MOUSE; NONHUMAN; SIGNAL TRANSDUCTION; TUMOR GROWTH; TUMOR XENOGRAFT;

ANIMALS; ANTINEOPLASTIC AGENTS; APOPTOSIS; APOPTOSIS INDUCING FACTOR; BCL-2-ASSOCIATED X PROTEIN; BREAST NEOPLASMS; CASPASE 3; CASPASE 8; CASPASE 9; CELL LINE, TUMOR; CELL SURVIVAL; CYTOCHROMES C; FEMALE; HUMANS; MICE; MICE, NUDE; NEOPLASM METASTASIS; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION; XANTHONES; XENOGRAFT MODEL ANTITUMOR ASSAYS;

ANIMALIA; MUS MUSCULUS;

EID: 84870526935     PISSN: 08298211     EISSN: 12086002     Source Type: Journal    
DOI: 10.1139/o2012-030     Document Type: Article

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