Solution conformation of the (-)-cis-anti-benzo[a]pyrenyl-dG adduct opposite dC in a DNA duplex: Intercalation of the covalently attached BP ring into the helix with base displacement of the modified deoxyguanosine into the major groove

Biochemistry

Volumn 35, Issue 30, 1996, Pages 9850-9863

  Cosman, Monique ^a,e   Hingerty, Brian E ^b   Luneva, Natalia ^c   Amin, Shantu ^c   Geacintov, Nicholas E ^c   Broyde, Suse ^d   Patel, Dinshaw J ^a  

^a MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

^b OAK RIDGE NATIONAL LABORATORY   (United States)

^c NEW YORK UNIVERSITY   (United States)

^d AMERICAN HEALTH FOUNDATION   (United States)

^e LAWRENCE LIVERMORE NATIONAL LABORATORY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DEOXYGUANOSINE; DOUBLE STRANDED DNA;

AMINO ACID SEQUENCE; ARTICLE; BASE PAIRING; CRYSTAL STRUCTURE; DNA ADDUCT; DNA CONFORMATION; DNA STRUCTURE; HYDROGEN BOND; NUCLEAR MAGNETIC RESONANCE; NUCLEAR OVERHAUSER EFFECT; PRIORITY JOURNAL; STEREOISOMERISM;

BASE COMPOSITION; BASE SEQUENCE; BENZO(A)PYRENE; DEOXYGUANOSINE; DNA; DNA ADDUCTS; HYDROGEN BONDING; INTERCALATING AGENTS; MAGNETIC RESONANCE SPECTROSCOPY; MODELS, MOLECULAR; MOLECULAR CONFORMATION; MOLECULAR SEQUENCE DATA; NUCLEIC ACID CONFORMATION; OLIGODEOXYRIBONUCLEOTIDES; SOLUTIONS;

EID: 0029764542     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi9605346     Document Type: Article

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