Rodent thyroid, liver, and fetal testis toxicity of the monoester metabolite of bis-(2-ethylhexyl) tetrabromophthalate (TBPH), a novel brominated flame retardant present in indoor dust

Environmental Health Perspectives

Volumn 120, Issue 12, 2012, Pages 1711-1719

  Springer, Cecilia ^a   Dere, Edward ^a,b   Hall, Susan J ^a   McDonnell, Elizabeth V ^a   Roberts, Simon C ^c   Butt, Craig M ^c   Stapleton, Heather M ^c   Watkins, Deborah J ^d,e   McClean, Michael D ^d   Webster, Thomas F ^d   Schlezinger, Jennifer J ^d   Boekelheide, Kim ^a  

^a BROWN UNIVERSITY   (United States)

^b RHODE ISLAND HOSPITAL   (United States)

^c DUKE UNIVERSITY   (United States)

^d BOSTON UNIVERSITY SCHOOL OF PUBLIC HEALTH   (United States)

^e BROWN UNIVERSITY   (United States)

Author keywords

Brominated; Exposure; Flame retardant; Hepatotoxicity; Hypothyroidism; Metabolism; Phthalate; PPAR; Toxicity

Indexed keywords

ALANINE AMINOTRANSFERASE; ALBUMIN; ALKALINE PHOSPHATASE; ASPARTATE AMINOTRANSFERASE; BIS (2 ETHYLHEXYL) TETRABROMOPHTHALATE; CALCIUM; CARBON DIOXIDE; CHLORIDE; CHOLESTEROL; CREATININE; DNA NUCLEOTIDYLEXOTRANSFERASE; ESTERASE; FLAME RETARDANT; GLUCOSE; KI 67 ANTIGEN; LIOTHYRONINE; MONO (2 ETHYHEXYL) TETRABROMOPHTHALATE; PERILIPIN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PHOSPHORUS; POTASSIUM; SODIUM; TESTOSTERONE; THYROXINE; TRIACYLGLYCEROL; UNCLASSIFIED DRUG; URIC ACID;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL DIFFERENTIATION; CONTROLLED STUDY; ENVIRONMENTAL EXPOSURE; ENZYME INHIBITION; FEMALE; FETUS; GAS CHROMATOGRAPHY; HISTOLOGY; HOUSE DUST; HUMAN; HYPOTHYROIDISM; IMMUNOHISTOCHEMISTRY; LIPID STORAGE; LIQUID CHROMATOGRAPHY; METABOLISM; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; REAL TIME POLYMERASE CHAIN REACTION; TANDEM MASS SPECTROMETRY; TOXICITY; WESTERN BLOTTING;

AIR POLLUTANTS; AIR POLLUTION, INDOOR; ANIMALS; AUTOMOBILES; BOSTON; BROMOBENZOATES; DUST; ENVIRONMENTAL EXPOSURE; ENVIRONMENTAL MONITORING; ESTERASES; FEMALE; FETUS; FLAME RETARDANTS; HALOGENATED DIPHENYL ETHERS; HOUSING; LIVER; MALE; PREGNANCY; RATS; RATS, INBRED F344; SWINE; TESTIS; THYROID GLAND; TISSUE DISTRIBUTION; WORKPLACE;

MURINAE; RATTUS; RODENTIA; SUS; TETRA; ZEA MAYS;

EID: 84870507651     PISSN: 00916765     EISSN: 15529924     Source Type: Journal    
DOI: 10.1289/ehp.1204932     Document Type: Article

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