Quantitative evaluation of alternative mechanisms of blood and testes disposition of Di(2-ethylhexyl) phthalate and mono(2-ethylhexyl) phthalate in rats

Toxicological Sciences

Volumn 49, Issue 2, 1999, Pages 172-185

  Keys, Deborah A ^a,b   Wallace, Duncan G ^b   Kepler, Thomas B ^a   Conolly, Rory B ^b  

^a NORTH CAROLINA STATE UNIVERSITY   (United States)

^b CIIT CENTERS FOR HEALTH RESEARCH   (United States)

Author keywords

DEHP; Diffusion limited; Enterohepatic circulation; Flow limited; Log likelihood ratio test; MEHP; Model; PBPK; PH trapping; Phthalates

Indexed keywords

PHTHALIC ACID 2 ETHYLHEXYL MONOESTER; PHTHALIC ACID BIS(2 ETHYLHEXYL) ESTER;

ANIMAL TISSUE; ARTICLE; BLOOD TOXICITY; DOSIMETRY; ENTEROHEPATIC CIRCULATION; INTRAVENOUS DRUG ADMINISTRATION; KINETICS; METABOLISM; NONHUMAN; ORAL DRUG ADMINISTRATION; PARTITION COEFFICIENT; RAT; REPRODUCTIVE TOXICITY; TISSUE LEVEL;

ANIMALS; DIFFUSION; ENTEROHEPATIC CIRCULATION; HYDROGEN-ION CONCENTRATION; MALE; MODELS, BIOLOGICAL; PHTHALIC ACIDS; PLASTICIZERS; RATS; RATS, SPRAGUE-DAWLEY; SOLUBILITY; TESTIS;

ANIMALIA;

EID: 0033030726     PISSN: 10966080     EISSN: None     Source Type: Journal    
DOI: 10.1093/toxsci/49.2.172     Document Type: Article

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