Human fetal testis xenografts are resistant to phthalate-induced endocrine disruption

Environmental Health Perspectives

Volumn 120, Issue 8, 2012, Pages 1137-1143

  Heger, Nicholas E ^a   Hall, Susan J ^a   Sandrof, Moses A ^a   Mcdonnell, Elizabeth V ^a   Hensley, Janan B ^b   McDowell, Erin N ^c   Martin, Kayla A ^c   Gaido, Kevin W ^d   Johnson, Kamin J ^c   Boekelheide, Kim ^a  

^a BROWN UNIVERSITY   (United States)

^b HAMNER INSTITUTES FOR HEALTH SCIENCES   (United States)

^c NEMOURS ALFRED I DUPONT HOSPITAL FOR CHILDREN   (United States)

^d CENTER FOR DRUG EVALUATION AND RESEARCH   (United States)

Author keywords

Animal model; Fetal testis; Human; Mouse; Multinucleated germ cells; Phthalate; Rat; Seminiferous cords; Testicular dysgenesis; Xenotransplant

Indexed keywords

CHOLESTEROL MONOOXYGENASE (SIDE CHAIN CLEAVING); PHTHALIC ACID; TESTOSTERONE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ENVIRONMENTAL EXPOSURE; FETUS; GENE EXPRESSION; GERM CELL; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MALE; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; STEROIDOGENESIS; TESTIS; XENOGRAFT;

ENDOCRINE DISRUPTORS; FEMALE; HUMANS; IMMUNOHISTOCHEMISTRY; MALE; PHTHALIC ACIDS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; TESTIS; TRANSPLANTATION, HETEROLOGOUS;

ANIMALIA; MUS; RATTUS; RODENTIA;

EID: 84864762655     PISSN: 00916765     EISSN: 15529924     Source Type: Journal    
DOI: 10.1289/ehp.1104711     Document Type: Article

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