-
1
-
-
79959517565
-
Human fatty liver disease: Old questions and new insights
-
Cohen, J.C.; Horton, J.D.; Hobbs, H.H. Human fatty liver disease: old questions and new insights. Science, 2011, 332, 1519-23.
-
(2011)
Science
, vol.332
, pp. 1519-1523
-
-
Cohen, J.C.1
Horton, J.D.2
Hobbs, H.H.3
-
2
-
-
79960029926
-
Systematic review: The epidemiology and natural history of non-alcoholic fatty liver disease and non-alcoholic steatohepatitis in adults
-
Vernon, G.; Baranova, A.; Younossi, Z.M. Systematic review: the epidemiology and natural history of non-alcoholic fatty liver disease and non-alcoholic steatohepatitis in adults. Aliment. Pharmacol. Ther., 2011, 34, 274-85.
-
(2011)
Aliment. Pharmacol. Ther.
, vol.34
, pp. 274-285
-
-
Vernon, G.1
Baranova, A.2
Younossi, Z.M.3
-
3
-
-
79959848854
-
Lipids in the wrong place: Visceral fat and nonalcoholicsteatohepatitis
-
Perseghin, G. Lipids in the wrong place: visceral fat and nonalcoholicsteatohepatitis. Diabetes Care, 2011,34 Suppl 2, S367-70.
-
(2011)
Diabetes Care
, vol.34
, Issue.SUPPL. 2
-
-
Perseghin, G.1
-
4
-
-
79954498879
-
Inflammation in nonalcoholic steatohepatitis
-
Harmon, R.C.; Tiniakos, D.G.; Argo, C.K. Inflammation in nonalcoholic steatohepatitis. Expert. Rev. Gastroenterol. Hepatol, 2011, 5, 189-200.
-
(2011)
Expert. Rev. Gastroenterol. Hepatol
, vol.5
, pp. 189-200
-
-
Harmon, R.C.1
Tiniakos, D.G.2
Argo, C.K.3
-
5
-
-
79959284653
-
Update on fatty liver disease and steatohepatitis
-
Aly, F.Z.; Kleiner, D.E. Update on fatty liver disease and steatohepatitis. Adv. Anat. Pathol., 2011, 18, 294-300.
-
(2011)
Adv. Anat. Pathol.
, vol.18
, pp. 294-300
-
-
Aly, F.Z.1
Kleiner, D.E.2
-
6
-
-
79958169116
-
Non-alcoholic fatty liver disease: A massive problem
-
Day, C.P. Non-alcoholic fatty liver disease: a massive problem. Clin. Med., 2011, 11, 176-8.
-
(2011)
Clin. Med.
, vol.11
, pp. 176-178
-
-
Day, C.P.1
-
7
-
-
79961206915
-
Mechanisms of lipotoxicity in NAFLD and clinical implications
-
Ibrahim, S.H.; Kohli, R.; Gores, G.J. Mechanisms of Lipotoxicity in NAFLD and Clinical Implications. J. Pediatr. Gastroenterol. Nutr., 2011, 53, 131-40.
-
(2011)
J. Pediatr. Gastroenterol. Nutr.
, vol.53
, pp. 131-140
-
-
Ibrahim, S.H.1
Kohli, R.2
Gores, G.J.3
-
8
-
-
79954484164
-
Fibrosis in alcoholic and nonalcoholic steatohepatitis
-
Bataller, R.; Rombouts, K.; Altamirano, J.; Marra, F. Fibrosis in alcoholic and nonalcoholic steatohepatitis. Best Pract Res Clin. Gastroenterol., 2011, 25, 231-244.
-
(2011)
Best Pract Res Clin. Gastroenterol.
, vol.25
, pp. 231-244
-
-
Bataller, R.1
Rombouts, K.2
Altamirano, J.3
Marra, F.4
-
10
-
-
38849173251
-
Comparison of the natural history of alcoholic and nonalcoholic fatty liver disease
-
Mills, S.J.; Harrison, S.A. Comparison of the natural history of alcoholic and nonalcoholic fatty liver disease. Curr. Gastroenterol. Rep., 2005, 7, 32-6.
-
(2005)
Curr. Gastroenterol. Rep.
, vol.7
, pp. 32-36
-
-
Mills, S.J.1
Harrison, S.A.2
-
11
-
-
77954791557
-
Molecular basis and current treatment for alcoholic liver disease
-
Miranda-Mendez, A.; Lugo-Baruqui, A.; Armendariz-Borunda, J. Molecular basis and current treatment for alcoholic liver disease. Int. J. Environ. Res. Public Health, 2010, 7, 1872-88.
-
(2010)
Int. J. Environ. Res. Public Health
, vol.7
, pp. 1872-1888
-
-
Miranda-Mendez, A.1
Lugo-Baruqui, A.2
Armendariz-Borunda, J.3
-
12
-
-
61549111852
-
New concepts in the pathogenesis of alcoholic liver disease
-
Albano, E. New concepts in the pathogenesis of alcoholic liver disease. Expert Rev. Gastroenterol. Hepatol., 2008, 2, 749-59.
-
(2008)
Expert Rev. Gastroenterol. Hepatol.
, vol.2
, pp. 749-759
-
-
Albano, E.1
-
13
-
-
0037067570
-
Role for stearoyl-CoA desaturase-1 in leptin-mediated weight loss
-
Cohen, P.; Miyazaki, M.; Socci, N.D.; Hagge-Greenberg, A.; Liedtke, W.; Soukas, A.A.; Sharma, R.; Hudgins, L.C.; Ntambi, J.M.; Friedman, J.M. Role for stearoyl-CoA desaturase-1 in leptin-mediated weight loss. Science, 2002, 297, 240-243.
-
(2002)
Science
, vol.297
, pp. 240-243
-
-
Cohen, P.1
Miyazaki, M.2
Socci, N.D.3
Hagge-Greenberg, A.4
Liedtke, W.5
Soukas, A.A.6
Sharma, R.7
Hudgins, L.C.8
Ntambi, J.M.9
Friedman, J.M.10
-
14
-
-
78149284997
-
Role of hepatic desaturases in obesity-related metabolic disorders
-
Bjermo, H.; Riserus, U. Role of hepatic desaturases in obesity-related metabolic disorders. Curr. Opin. Clin. Nutr. Metab. Care, 2010, 13, 703-708.
-
(2010)
Curr. Opin. Clin. Nutr. Metab. Care
, vol.13
, pp. 703-708
-
-
Bjermo, H.1
Riserus, U.2
-
15
-
-
77950612089
-
A subset of dysregulated metabolic and survival genes is associated with severity of hepatic steatosis in obese Zucker rats
-
Buque, X.; Martinez, M. J.; Cano, A.; Miquilena-Colina, M.E.; García-Monzón, C.; Aspichueta, P.; Ochoa, B. A subset of dysregulated metabolic and survival genes is associated with severity of hepatic steatosis in obese Zucker rats. J. Lipid Res., 2010, 51, 500-513.
-
(2010)
J. Lipid Res.
, vol.51
, pp. 500-513
-
-
Buque, X.1
Martinez, M.J.2
Cano, A.3
Miquilena-Colina, M.E.4
García- Monzón, C.5
Aspichueta, P.6
Ochoa, B.7
-
16
-
-
17844383478
-
Effects of diet and genetic background on sterol regulatory element-binding protein-1c, stearoyl-CoA desaturase 1, and the development of the metabolic syndrome
-
Biddinger, S. B.; Almind, K.; Miyazaki, M.; Kokkotou, E.; Ntambi, J.M.; Kahn, C.R. Effects of diet and genetic background on sterol regulatory element-binding protein-1c, stearoyl-CoA desaturase 1, and the development of the metabolic syndrome. Diabetes, 2005 54, 1314-1323.
-
(2005)
Diabetes
, vol.54
, pp. 1314-1323
-
-
Biddinger, S.B.1
Almind, K.2
Miyazaki, M.3
Kokkotou, E.4
Ntambi, J.M.5
Kahn, C.R.6
-
17
-
-
77949444189
-
Analysis of transcriptome and metabolome profiles alterations in fatty liver induced by high-fat diet in rat
-
Xie, Z.; Li. H.; Wang, K.; Lin, J.; Wang, Q.; Zhao, G.; Jia, W.; Zhang, Q. Analysis of transcriptome and metabolome profiles alterations in fatty liver induced by high-fat diet in rat. Metabolism, 2010, 59, 554-560.
-
(2010)
Metabolism
, vol.59
, pp. 554-560
-
-
Xie, Z.1
Li, H.2
Wang, K.3
Lin, J.4
Wang, Q.5
Zhao, G.6
Jia, W.7
Zhang, Q.8
-
18
-
-
33645820583
-
Liver-directed overexpression of mitochondrial glycerol-3-phosphate acyltransferase results in hepatic steatosis, increased triacylglycerol secretion and reduced fatty acid oxidation
-
Linden, D.; William-Olsson, L.; Ahnmark, A.; Ekroos, K.; Hallberg, C.; Sjögren, H.P.; Becker, B.; Svensson, L.; Clapham, J.C.; Oscarsson, J.; Schreyer, S. Liver-directed overexpression of mitochondrial glycerol-3-phosphate acyltransferase results in hepatic steatosis, increased triacylglycerol secretion and reduced fatty acid oxidation. FASEB J., 2006, 20, 434-443.
-
(2006)
FASEB J.
, vol.20
, pp. 434-443
-
-
Linden, D.1
William-Olsson, L.2
Ahnmark, A.3
Ekroos, K.4
Hallberg, C.5
Sjögren, H.P.6
Becker, B.7
Svensson, L.8
Clapham, J.C.9
Oscarsson, J.10
Schreyer, S.11
-
19
-
-
79955775364
-
The metabolic cascade leading to eicosanoid precursors-desaturases, elongases, and phospholipases A2-is altered in Zucker fatty rats
-
Fevre, C.; Bellenger, S.; Pierre, A.S.; Minville, M.; Bellenger, J.; Gresti, J.; Rialland, M.; Narce, M.; Tessier, C. The metabolic cascade leading to eicosanoid precursors-desaturases, elongases, and phospholipases A2-is altered in Zucker fatty rats. Biochim. Biophys. Acta., 2011, 1811, 409-417.
-
(2011)
Biochim. Biophys. Acta.
, vol.1811
, pp. 409-417
-
-
Fevre, C.1
Bellenger, S.2
Pierre, A.S.3
Minville, M.4
Bellenger, J.5
Gresti, J.6
Rialland, M.7
Narce, M.8
Tessier, C.9
-
20
-
-
69249213918
-
Pharmacological inhibition of stearoyl-CoA desaturase 1 improves insulin sensitivity in insulin-resistant rat models
-
Issandou, M.; Bouillot; A.; Brusq. J.M.; Forest. M.C.; Grillot, D.; Guillard, R.; Martin, S.; Michiels, C.; Sulpice, T.; Daugan, A.Pharmacological inhibition of stearoyl-CoA desaturase 1 improves insulin sensitivity in insulin-resistant rat models. Eur. J. Pharmacol., 2009, 618, 28-36.
-
(2009)
Eur. J. Pharmacol.
, vol.618
, pp. 28-36
-
-
Issandou, M.1
Bouillot, A.2
Brusq, J.M.3
Forest, M.C.4
Grillot, D.5
Guillard, R.6
Martin, S.7
Michiels, C.8
Sulpice, T.9
Daugan, A.10
-
21
-
-
77955500907
-
Dietary fat intake promotes the development of hepatic steatosis independently from excess caloric consumption in a murine model
-
de Meijer, V. E.; Le, H.D.; Meisel, J.A.; Akhavan, S.M.R.; Pan, A.; Nosé, V.; Puder, M. Dietary fat intake promotes the development of hepatic steatosis independently from excess caloric consumption in a murine model. Metabolism, 2010, 59, 1092-1105.
-
(2010)
Metabolism
, vol.59
, pp. 1092-1105
-
-
Le De Meijer, V.E.H.D.1
Meisel, J.A.2
Akhavan, S.M.R.3
Pan, A.4
Nosé, V.5
Puder, M.6
-
22
-
-
0024444947
-
Liver microsomal delta 6 and delta 5 linoleic acid desaturation in female BB rats
-
Chanussot, B.; Narce, M.; Poisson, J.P. Liver microsomal delta 6 and delta 5 linoleic acid desaturation in female BB rats. Diabetologia, 1989, 32,786-91.
-
(1989)
Diabetologia
, vol.32
, pp. 786-791
-
-
Chanussot, B.1
Narce, M.2
Poisson, J.P.3
-
23
-
-
2942585486
-
Role of fatty acid composition in the development of metabolic disorders in sucrose-induced obese rats
-
Fukuchi, S.K.; Hamaguchi, K.; Seike, M.; Himeno, K.; Sakata, T.; Yoshimatsu, H. Role of fatty acid composition in the development of metabolic disorders in sucrose-induced obese rats. Exp. Biol. Med., 2004, 229, 486-493.
-
(2004)
Exp. Biol. Med.
, vol.229
, pp. 486-493
-
-
Fukuchi, S.K.1
Hamaguchi, K.2
Seike, M.3
Himeno, K.4
Sakata, T.5
Yoshimatsu, H.6
-
24
-
-
78649667416
-
Attenuated progression of diet-induced steatohepatitis in glutathione-deficient mice
-
Haque, J. A.; McMahan, R.S.; Campbell, J.S.; Shimizu-Albergine, M.; Wilson, A.M.; Botta, D.; Bammler, T.K.; Beyer, R.P.; Montine, T.J.; Yeh, M.M.; Kavanagh, T.J.; Fausto, N. Attenuated progression of diet-induced steatohepatitis in glutathione-deficient mice. Lab. Invest., 2010, 90, 1704-1717.
-
(2010)
Lab. Invest.
, vol.90
, pp. 1704-1717
-
-
Haque, J.A.1
McMahan, R.S.2
Campbell, J.S.3
Shimizu-Albergine, M.4
Wilson, A.M.5
Botta, D.6
Bammler, T.K.7
Beyer, R.P.8
Montine, T.J.9
Yeh, M.M.10
Kavanagh, T.J.11
Fausto, N.12
-
25
-
-
4444358045
-
Leptin and the control of metabolism: Role for stearoyl-CoA desaturase-1 (SCD-1)
-
Cohen, P.; Friedman, J. M. "Leptin and the control of metabolism: role for stearoyl-CoA desaturase-1 (SCD-1). J. Nutr., 2004, 134, 2455S-2463S.
-
(2004)
J. Nutr.
, vol.134
-
-
Cohen, P.1
Friedman, J.M.2
-
26
-
-
33747034520
-
Leptin suppresses stearoyl-CoA desaturase 1 by mechanisms independent of insulin and sterol regulatory element-binding protein-1c
-
Biddinger, S. B.; Miyazaki, M.; Boucher, J.; Ntambi, J.M.; Kahn, C.R.Leptin suppresses stearoyl-CoA desaturase 1 by mechanisms independent of insulin and sterol regulatory element-binding protein-1c. Diabetes, 2006, 55, 2032-2041.
-
(2006)
Diabetes
, vol.55
, pp. 2032-2041
-
-
Biddinger, S.B.1
Miyazaki, M.2
Boucher, J.3
Ntambi, J.M.4
Kahn, C.R.5
-
27
-
-
77249131862
-
Key role of the ERK1/2 MAPK pathway in the transcriptional regulation of the Stearoyl-CoA Desaturase (SCD1) gene expression in response to leptin
-
Mauvoisin, D.; Prévost, M.; Ducheix, S.; Arnaud, M.P.; Mounier, C.Key role of the ERK1/2 MAPK pathway in the transcriptional regulation of the Stearoyl-CoA Desaturase (SCD1) gene expression in response to leptin. Mol. Cell. Endocrinol., 2010, 319, 116-128.
-
(2010)
Mol. Cell. Endocrinol.
, vol.319
, pp. 116-128
-
-
Mauvoisin, D.1
Prévost, M.2
Ducheix, S.3
Arnaud, M.P.4
Mounier, C.5
-
28
-
-
0037143752
-
Loss of stearoyl-CoA desaturase-1 function protects mice against adiposity
-
Ntambi, J. M.; Miyazaki, M.; Stoehr, J.P.; Lan, H.; Kendziorski, C.M.; Yandell, B.S.; Song, Y.; Cohen, P.; Friedman, J.M.; Attie, A.D. Loss of stearoyl-CoA desaturase-1 function protects mice against adiposity. Proc Natl. Acad. Sci. U. S. A., 2002, 99, 11482-11486.
-
(2002)
Proc Natl. Acad. Sci. U. S. A.
, vol.99
, pp. 11482-11486
-
-
Ntambi, J.M.1
Miyazaki, M.2
Stoehr, J.P.3
Lan, H.4
Kendziorski, C.M.5
Yandell, B.S.6
Song, Y.7
Cohen, P.8
Friedman, J.M.9
Attie, A.D.10
-
29
-
-
38049169032
-
R Absence of stearoyl-CoA desaturase-1 ameliorates features of the metabolic syndrome in LDLR-deficient mice
-
MacDonald, M. L.; Singaraja, R.R.; Bissada, N.; Ruddle, P.; Watts, R.; Karasinska, J.M.; Gibson, W.T.; Fievet, C.; Vance, J.E.; Staels, B.; Hayden, M.R Absence of stearoyl-CoA desaturase-1 ameliorates features of the metabolic syndrome in LDLR-deficient mice. J. Lipid Res., 2008, 49, 217-229.
-
(2008)
J. Lipid Res.
, vol.49
, pp. 217-229
-
-
MacDonald, M.L.1
Singaraja, R.R.2
Bissada, N.3
Ruddle, P.4
Watts, R.5
Karasinska, J.M.6
Gibson, W.T.7
Fievet, C.8
Vance, J.E.9
Staels, B.10
Hayden, M.11
-
30
-
-
77956822412
-
Loss of stearoyl-CoA desaturase 1 rescues cardiac function in obese leptin-deficient mice
-
Dobrzyn, P.; Dobrzyn, A.; Miyazaki, M.; Ntambi, J.M. Loss of stearoyl-CoA desaturase 1 rescues cardiac function in obese leptin-deficient mice. J. Lipid Res., 2010, 51, 2202-2210.
-
(2010)
J. Lipid Res.
, vol.51
, pp. 2202-2210
-
-
Dobrzyn, P.1
Dobrzyn, A.2
Miyazaki, M.3
Ntambi, J.M.4
-
31
-
-
54049132164
-
Inhibition of stearoyl-coenzyme A desaturase 1 dissociates insulin resistance and obesity from atherosclerosis
-
Brown, J. M.; Chung, S.; Sawyer, J.K.; Degirolamo, C.; Alger, H.M.; Nguyen, T.; Zhu, X.; Duong, M.N.; Wibley, A.L.; Shah, R.; Davis, M.A.; Kelley, K.; Wilson, M.D.; Kent, C.; Parks, J.S.; Rudel, L.L. Inhibition of stearoyl-coenzyme A desaturase 1 dissociates insulin resistance and obesity from atherosclerosis. Circulation, 2008, 118, 1467-1475.
-
(2008)
Circulation
, vol.118
, pp. 1467-1475
-
-
Brown, J.M.1
Chung, S.2
Sawyer, J.K.3
Degirolamo, C.4
Alger, H.M.5
Nguyen, T.6
Zhu, X.7
Duong, M.N.8
Wibley, A.L.9
Shah, R.10
Davis, M.A.11
Kelley, K.12
Wilson, M.D.13
Kent, C.14
Parks, J.S.15
Rudel, L.L.16
-
32
-
-
43249127067
-
Role of stearoyl-coenzyme A desaturase in regulating lipid metabolism
-
Flowers, M. T. Ntambi, J. M. Role of stearoyl-coenzyme A desaturase in regulating lipid metabolism. Curr. Opin. Lipidol., 2008, 19, 248-256.
-
(2008)
Curr. Opin. Lipidol.
, vol.19
, pp. 248-256
-
-
Flowers, M.T.1
Ntambi, J.M.2
-
33
-
-
20144388684
-
Prevention of obesity in mice by antisense oligonucleotide inhibitors of stearoyl-CoA desaturase-1
-
Jiang, G.; Li, Z. Prevention of obesity in mice by antisense oligonucleotide inhibitors of stearoyl-CoA desaturase-1. J. Clin. Invest., 2005,115, 1030-1038.
-
(2005)
J. Clin. Invest.
, vol.115
, pp. 1030-1038
-
-
Jiang, G.1
Li, Z.2
-
34
-
-
33745212925
-
Critical role of stearoyl-CoA desaturase-1 (SCD-1) in the onset of diet-induced hepatic insulin resistance
-
Gutierrez-Juarez, R.; Pocai. A.; Mulas, C.; Ono, H.; Bhanot, S.; Monia, B.P.; Rossetti, L. Critical role of stearoyl-CoA desaturase-1 (SCD-1) in the onset of diet-induced hepatic insulin resistance. J. Clin. Invest., 2006, 116, 1686-1695.
-
(2006)
J. Clin. Invest.
, vol.116
, pp. 1686-1695
-
-
Gutierrez-Juarez, R.1
Pocai, A.2
Mulas, C.3
Ono, H.4
Bhanot, S.5
Monia, B.P.6
Rossetti, L.7
-
35
-
-
67449101455
-
Down-regulation of hepatic stearoyl-CoA desaturase 1 expression by angiotensin II receptor blocker in the obese fa/fa Zucker rat: Possible role in amelioration of insulin resistance and hepatic steatosis
-
Yokozawa, J., Sasaki. T.; Ohwada, K.; Sasaki, Y.; Ito, J.I.; Saito, T.; Kawata, S. Down-regulation of hepatic stearoyl-CoA desaturase 1 expression by angiotensin II receptor blocker in the obese fa/fa Zucker rat: possible role in amelioration of insulin resistance and hepatic steatosis. J. Gastroenterol., 2009, 44, 583-591.
-
(2009)
J. Gastroenterol.
, vol.44
, pp. 583-591
-
-
Yokozawa, J.1
Sasaki, T.2
Ohwada, K.3
Sasaki, Y.4
Ito, J.I.5
Saito, T.6
Kawata, S.7
-
36
-
-
79952534308
-
Green tea extract attenuates hepatic steatosis by decreasing adipose lipogenesis and enhancing hepatic antioxidant defenses in ob/ob mice
-
Park, H. J.; DiNatale, D.A.; Chung, M.Y.; Park, Y.K.; Lee, J.Y.; Koo, S.I.; O'Connor, M.; Manautou, J.E.; Bruno, R.S. Green tea extract attenuates hepatic steatosis by decreasing adipose lipogenesis and enhancing hepatic antioxidant defenses in ob/ob mice. J. Nutr. Biochem., 2011, 22, 393-400.
-
(2011)
J. Nutr. Biochem.
, vol.22
, pp. 393-400
-
-
Park, H.J.1
Dinatale, D.A.2
Chung, M.Y.3
Park, Y.K.4
Lee, J.Y.5
Koo, S.I.6
O'Connor, M.7
Manautou, J.E.8
Bruno, R.S.9
-
37
-
-
65549136260
-
Hepatic lipid partitioning and liver damage in nonalcoholic fatty liver disease: Role of stearoyl-CoA desaturase
-
Li, Z.Z.; Berk, M.; McIntyre, T.M.; Feldstein, A.E. Hepatic lipid partitioning and liver damage in nonalcoholic fatty liver disease: role of stearoyl-CoA desaturase. J. Biol. Chem., 2009, 284, 5637-5644.
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 5637-5644
-
-
Li, Z.Z.1
Berk, M.2
McIntyre, T.M.3
Feldstein, A.E.4
-
38
-
-
68049142428
-
Individual stearoyl-coa desaturase 1 expression modulates endoplasmic reticulum stress and inflammation in human myotubes and is associated with skeletal muscle lipid storage and insulin sensitivity in vivo
-
Peter, A.; Weigert, C.; Staiger, H.; Machicao, F.; Schick, F.; Machann, J.; Stefan, N.; Thamer, C.; Häring, H.U.; Schleicher, E. Individual stearoyl-coa desaturase 1 expression modulates endoplasmic reticulum stress and inflammation in human myotubes and is associated with skeletal muscle lipid storage and insulin sensitivity in vivo. Diabetes, 2009, 58, 1757-1765.
-
(2009)
Diabetes
, vol.58
, pp. 1757-1765
-
-
Peter, A.1
Weigert, C.2
Staiger, H.3
MacHicao, F.4
Schick, F.5
MacHann, J.6
Stefan, N.7
Thamer, C.8
Häring, H.U.9
Schleicher, E.10
-
39
-
-
0036297756
-
Desaturation and elongation of Fatty acids and insulin action
-
Vessby, B.; Gustafsson, I.B.; Tengblad, S.; Boberg, M.; Andersson, A.Desaturation and elongation of Fatty acids and insulin action. Ann. N. Y. Acad. Sci., 2002, 967, 183-195.
-
(2002)
Ann. N. Y. Acad. Sci.
, vol.967
, pp. 183-195
-
-
Vessby, B.1
Gustafsson, I.B.2
Tengblad, S.3
Boberg, M.4
Andersson, A.5
-
40
-
-
47249090603
-
Effects of saturated and unsaturated fatty acids on estimated desaturase activities during a controlled dietary intervention
-
Warensjö, E.; Risérus, U.; Gustafsson, .IB.; Mohsen, R.; Cederholm, T.; Vessby, B. Effects of saturated and unsaturated fatty acids on estimated desaturase activities during a controlled dietary intervention. Nutr. Metab. Cardiovasc. Dis., 2008, 18, 683-690.
-
(2008)
Nutr. Metab. Cardiovasc. Dis.
, vol.18
, pp. 683-690
-
-
Warensjö, E.1
Risérus, U.2
Gustafsson, I.B.3
Mohsen, R.4
Cederholm, T.5
Vessby, B.6
-
41
-
-
34548761014
-
Liver fat in the metabolic syndrome
-
Kotronen, A.; Westerbacka, J.; Bergholm, R.; Pietiläinen, K.H.; Yki-Järvinen, H. Liver fat in the metabolic syndrome. J. Clin. Endocrinol. Metab., 2007, 92, 3490-3497.
-
(2007)
J. Clin. Endocrinol. Metab.
, vol.92
, pp. 3490-3497
-
-
Kotronen, A.1
Westerbacka, J.2
Bergholm, R.3
Pietiläinen, K.H.4
Yki-Järvinen, H.5
-
42
-
-
63249121641
-
Hepatic stearoyl-CoA desaturase (SCD)-1 activity and diacylglycerol but not ceramide concentrations are increased in the nonalcoholic human fatty liver
-
Kotronen, A.; Seppänen-Laakso, T.; Westerbacka, J.; Kiviluoto, T.; Arola, J.; Ruskeepää, A.L.; Oresic, M.; Yki-Järvinen, H. Hepatic stearoyl-CoA desaturase (SCD)-1 activity and diacylglycerol but not ceramide concentrations are increased in the nonalcoholic human fatty liver. Diabetes, 2009, 58, 203-208.
-
(2009)
Diabetes
, vol.58
, pp. 203-208
-
-
Kotronen, A.1
Seppänen-Laakso, T.2
Westerbacka, J.3
Kiviluoto, T.4
Arola, J.5
Ruskeepää, A.L.6
Oresic, M.7
Yki-Järvinen, H.8
-
43
-
-
26244436986
-
Fatty acid composition of serum lipids predicts the development of the metabolic syndrome in men
-
Warensjo, E.; Risérus, U.; Vessby, B. Fatty acid composition of serum lipids predicts the development of the metabolic syndrome in men. Diabetologia, 2005, 48, 1999-2005.
-
(2005)
Diabetologia
, vol.48
, pp. 1999-2005
-
-
Warensjo, E.1
Risérus, U.2
Vessby, B.3
-
44
-
-
33644881910
-
Fatty acid composition and estimated desaturase activities are associated with obesity and lifestyle variables in men and women
-
Warensjo, E.; Ohrvall, M.; Vessby. B. Fatty acid composition and estimated desaturase activities are associated with obesity and lifestyle variables in men and women. Nutr. Metab. Cardiovasc. Dis., 2006, 16, 128-136.
-
(2006)
Nutr. Metab. Cardiovasc. Dis.
, vol.16
, pp. 128-136
-
-
Warensjo, E.1
Ohrvall, M.2
Vessby, B.3
-
45
-
-
58249092178
-
The association of desaturase 9 and plasma fatty acid composition with insulin resistance-associated factors in female adolescents
-
Zhou, Y. E.; Egeland, G.M.; Meltzer, S.J.; Kubow, S. The association of desaturase 9 and plasma fatty acid composition with insulin resistance- associated factors in female adolescents. Metabolism, 2009, 58, 158-166.
-
(2009)
Metabolism
, vol.58
, pp. 158-166
-
-
Zhou, Y.E.1
Egeland, G.M.2
Meltzer, S.J.3
Kubow, S.4
-
46
-
-
36048996277
-
Long-term predictors of insulin resistance: Role of lifestyle and metabolic factors in middle-aged men
-
Riserus, U.; Arnlöv, J.; Berglund, L. Long-term predictors of insulin resistance: role of lifestyle and metabolic factors in middle-aged men. Diabetes Care, 2007, 30, 2928-2933.
-
(2007)
Diabetes Care
, vol.30
, pp. 2928-2933
-
-
Riserus, U.1
Arnlöv, J.2
Berglund, L.3
-
47
-
-
33748477872
-
Improvements in glucose tolerance and insulin sensitivity after lifestyle intervention are related to changes in serum fatty acid profile and desaturase activities: The SLIM study
-
Corpeleijn, E.; Feskens, E.J.; Jansen, E.H.; Mensink, M.; Saris, W.H.; de Bruin, T.W.; Blaak, E.E. Improvements in glucose tolerance and insulin sensitivity after lifestyle intervention are related to changes in serum fatty acid profile and desaturase activities: the SLIM study. Diabetologia, 2006, 49, 2392-2401.
-
(2006)
Diabetologia
, vol.49
, pp. 2392-2401
-
-
Corpeleijn, E.1
Feskens, E.J.2
Jansen, E.H.3
Mensink, M.4
Saris, W.H.5
De Bruin, T.W.6
Blaak, E.E.7
-
48
-
-
34547947590
-
Polymorphisms in the SCD-1 gene: Associations with body fat distribution and insulin sensitivity
-
Warensjo, E.; Ingelsson, E.; Lundmark, P.; Lannfelt, L.; Syvänen, A.C.; Vessby, B.; Risérus, U. Polymorphisms in the SCD-1 gene: associations with body fat distribution and insulin sensitivity. Obesity, 2007, 15, 1732-1740.
-
(2007)
Obesity
, vol.15
, pp. 1732-1740
-
-
Warensjo, E.1
Ingelsson, E.2
Lundmark, P.3
Lannfelt, L.4
Syvänen, A.C.5
Vessby, B.6
Risérus, U.7
-
49
-
-
66349126363
-
Microarray analysis of hepatic gene expression identifies new genes involved in steatotic liver
-
Guillen, N.; Navarro, M.A.; Arnal, C.; Noone, E.; Arbonés-Mainar, J.M.; Acín, S.; Surra, J.C.; Muniesa, P.; Roche, H.M.; Osada, J. Microarray analysis of hepatic gene expression identifies new genes involved in steatotic liver. Physiol. Genomics, 2009, 37, 187-198.
-
(2009)
Physiol. Genomics
, vol.37
, pp. 187-198
-
-
Guillen, N.1
Navarro, M.A.2
Arnal, C.3
Noone, E.4
Arbonés-Mainar, J.M.5
Acín, S.6
Surra, J.C.7
Muniesa, P.8
Roche, H.M.9
Osada, J.10
-
50
-
-
37349074067
-
Identification of mutated Srebf1 as a QTL influencing risk for hepatic steatosis in the spontaneously hypertensive rat
-
Pravenec, M.; Kazdova, L.; Landa, V.; Zidek, V.; Mlejnek, P.; Simakova, M.; Jansa, P.; Forejt, J.; Kren, V.; Krenova, D.; Qi, N.; Wang, J.M.; Chan, D.; Aitman, T.J.; Kurtz, T.W. Identification of mutated Srebf1 as a QTL influencing risk for hepatic steatosis in the spontaneously hypertensive rat. Hypertension, 2008, 51, 148-153.
-
(2008)
Hypertension
, vol.51
, pp. 148-153
-
-
Pravenec, M.1
Kazdova, L.2
Landa, V.3
Zidek, V.4
Mlejnek, P.5
Simakova, M.6
Jansa, P.7
Forejt, J.8
Kren, V.9
Krenova, D.10
Qi, N.11
Wang, J.M.12
Chan, D.13
Aitman, T.J.14
Kurtz, T.W.15
-
51
-
-
65449149413
-
Liver X receptor mediates hepatitis B virus X protein-induced lipogenesis in hepatitis B virus-associated hepatocellular carcinoma
-
Na, T.Y.; Shin, Y.K.; Roh, K.J.; Kang, S.A.; Hong, I.; Oh, S.J.; Seong, J.K.; Park, C.K.; Choi, Y.L.; Lee, M.O. Liver X receptor mediates hepatitis B virus X protein-induced lipogenesis in hepatitis B virus-associated hepatocellular carcinoma. Hepatology, 2009, 49, 1122-1131.
-
(2009)
Hepatology
, vol.49
, pp. 1122-1131
-
-
Na, T.Y.1
Shin, Y.K.2
Roh, K.J.3
Kang, S.A.4
Hong, I.5
Oh, S.J.6
Seong, J.K.7
Park, C.K.8
Choi, Y.L.9
Lee, M.O.10
-
52
-
-
0345448923
-
Polyunsaturated fatty acids ameliorate hepatic steatosis in obese mice by SREBP-1 suppression
-
Sekiya, M.; Yahagi, N.; Matsuzaka, T.; Najima, Y.; Nakakuki, M.; Nagai, R.; Ishibashi, S.; Osuga, J.; Yamada, N.; Shimano, H. Polyunsaturated fatty acids ameliorate hepatic steatosis in obese mice by SREBP-1 suppression. Hepatology, 2003, 38, 1529-1539.
-
(2003)
Hepatology
, vol.38
, pp. 1529-1539
-
-
Sekiya, M.1
Yahagi, N.2
Matsuzaka, T.3
Najima, Y.4
Nakakuki, M.5
Nagai, R.6
Ishibashi, S.7
Osuga, J.8
Yamada, N.9
Shimano, H.10
-
53
-
-
1542410333
-
Dietary n-3 polyunsaturated fatty acids decrease hepatic triglycerides in Fischer 344 rats
-
Levy, J. R.; Clore, J.N.; Stevens, W. Dietary n-3 polyunsaturated fatty acids decrease hepatic triglycerides in Fischer 344 rats. Hepatology, 2004, 39, 608-616.
-
(2004)
Hepatology
, vol.39
, pp. 608-616
-
-
Levy, J.R.1
Clore, J.N.2
Stevens, W.3
-
54
-
-
0031781317
-
Membrane fluidity and fatty acid metabolism in kidney cells from rats fed purified eicosapentaenoic acid or purified docosahexaenoic acid
-
Hagve, T.A.; Woldseth, B; Brox, J.; Narce, M.; Poisson, J.P. Membrane fluidity and fatty acid metabolism in kidney cells from rats fed purified eicosapentaenoic acid or purified docosahexaenoic acid. Scand. J. Clin. Lab. Invest., 1998, 58,187-94.
-
(1998)
Scand. J. Clin. Lab. Invest.
, vol.58
, pp. 187-194
-
-
Hagve, T.A.1
Woldseth, B.2
Brox, J.3
Narce, M.4
Poisson, J.P.5
-
55
-
-
0030837686
-
Fatty acid metabolism, pharmacological nutrients and hypertension
-
Narce, M.; Frenoux, J.M.; Dardel, V.; Foucher, C.; Germain, S.; Delachambre, M.C.; Poisson, J.P. Fatty acid metabolism, pharmacological nutrients and hypertension. Biochimie, 1997, 79,135-8.
-
(1997)
Biochimie
, vol.79
, pp. 135-138
-
-
Narce, M.1
Frenoux, J.M.2
Dardel, V.3
Foucher, C.4
Germain, S.5
Delachambre, M.C.6
Poisson, J.P.7
-
56
-
-
0028863637
-
Influence of spontaneous hypertension on n-3 delta-6-desaturase activity and fatty acid composition of rat hepatocytes
-
Narce, M.; Asdrubal, P.; Delachambre, M.C.; Gresti, J.; Poisson, J.P. Influence of spontaneous hypertension on n-3 delta-6-desaturase activity and fatty acid composition of rat hepatocytes. Mol. Cell. Biochem., 1995, 152, 7-12.
-
(1995)
Mol. Cell. Biochem.
, vol.152
, pp. 7-12
-
-
Narce, M.1
Asdrubal, P.2
Delachambre, M.C.3
Gresti, J.4
Poisson, J.P.5
-
57
-
-
0033808142
-
Dietary docosahexaenoic acid affects stearic acid desaturation in spontaneously hypertensive rats
-
Engler, M. M.; Bellenger-Germain, S.H.; Engler, M.B.; Narce, M.M.; Poisson, J.P. Dietary docosahexaenoic acid affects stearic acid desaturation in spontaneously hypertensive rats. Lipids, 2000, 35, 1011-1015.
-
(2000)
Lipids
, vol.35
, pp. 1011-1015
-
-
Engler, M.M.1
Bellenger-Germain, S.H.2
Engler, M.B.3
Narce, M.M.4
Poisson, J.P.5
-
58
-
-
3042819785
-
A new hypotensive polyunsaturated fatty acid dietary combination regulates oleic acid accumulation by suppression of stearoyl CoA desaturase 1 gene expression in the SHR model of genetic hypertension
-
Bellenger, J.; Bellenger, S.; Clément, L.; Mandard, S.; Diot, C.; Poisson, J.P.; Narce, M. A new hypotensive polyunsaturated fatty acid dietary combination regulates oleic acid accumulation by suppression of stearoyl CoA desaturase 1 gene expression in the SHR model of genetic hypertension. FASEB J., 2004, 18, 773-775.
-
(2004)
FASEB J.
, vol.18
, pp. 773-775
-
-
Bellenger, J.1
Bellenger, S.2
Clément, L.3
Mandard, S.4
Diot, C.5
Poisson, J.P.6
Narce, M.7
-
59
-
-
73849124961
-
Combined therapy of dietary fish oil and stearoyl-CoA desaturase 1 inhibition prevents the metabolic syndrome and atherosclerosis
-
Brown, J. M.; Sawyer, J.K.; Degirolamo, C.; Alger, H.M.; Nguyen, T.M; Zhu, X.; Duong, M.N.; Brown, A.L.; Lord, C.; Shah, R.; Davis, M.A.; Kelley, K.; Wilson, M.D.; Madenspacher, J.; Fessler, M.B.; Parks, J.S.; Rudel, L.L.Combined therapy of dietary fish oil and stearoyl-CoA desaturase 1 inhibition prevents the metabolic syndrome and atherosclerosis. Arterioscler. Thromb. Vasc. Biol., 2010, 30, 24-30.
-
(2010)
Arterioscler. Thromb. Vasc. Biol.
, vol.30
, pp. 24-30
-
-
Brown, J.M.1
Sawyer, J.K.2
Degirolamo, C.3
Alger, H.M.4
Nguyen, T.M.5
Zhu, X.6
Duong, M.N.7
Brown, A.L.8
Lord, C.9
Shah, R.10
Davis, M.A.11
Kelley, K.12
Wilson, M.D.13
Madenspacher, J.14
Fessler, M.B.15
Parks, J.S.16
Rudel, L.L.17
-
60
-
-
67349249102
-
Highly purified eicosapentaenoic acid prevents the progression of hepatic steatosis by repressing monounsaturated fatty acid synthesis in high-fat/high-sucrose diet-fed mice
-
Kajikawa, S.; Harada, T.; Kawashima, A.; Imada, K.; Mizuguchi, K. Highly purified eicosapentaenoic acid prevents the progression of hepatic steatosis by repressing monounsaturated fatty acid synthesis in high-fat/high-sucrose diet-fed mice. Prostaglandins Leukot. Essent. Fatty Acids, 2009, 80, 229-238.
-
(2009)
Prostaglandins Leukot. Essent. Fatty Acids
, vol.80
, pp. 229-238
-
-
Kajikawa, S.1
Harada, T.2
Kawashima, A.3
Imada, K.4
Mizuguchi, K.5
-
61
-
-
34548527932
-
Conjugated linoleic acid does not reduce body fat but decreases hepatic steatosis in adult Wistar rats
-
Purushotham, A.; Shrode, G.E.; Wendel, A.A.; Liu, L.F.; Belury, M A. Conjugated linoleic acid does not reduce body fat but decreases hepatic steatosis in adult Wistar rats. J. Nutr. Biochem., 2007, 18, 676-684
-
(2007)
J. Nutr. Biochem.
, vol.18
, pp. 676-684
-
-
Purushotham, A.1
Shrode, G.E.2
Wendel, A.A.3
Liu, L.F.4
Belury, M.A.5
-
62
-
-
33646441619
-
Effects of conjugated linoleic acid and troglitazone on lipid accumulation and composition in lean and Zucker diabetic fatty (fa/fa) rats
-
Wendel, A. A.; Belury, M. A. Effects of conjugated linoleic acid and troglitazone on lipid accumulation and composition in lean and Zucker diabetic fatty (fa/fa) rats. Lipids, 2006, 41, 241-247.
-
(2006)
Lipids
, vol.41
, pp. 241-247
-
-
Wendel, A.A.1
Belury, M.A.2
-
63
-
-
34447499065
-
Combined effects of rosiglitazone and conjugated linoleic acid on adiposity, insulin sensitivity, and hepatic steatosis in high-fat-fed mice
-
Liu, L. F., Purushotham A, Wendel AA, Belury MA. Combined effects of rosiglitazone and conjugated linoleic acid on adiposity, insulin sensitivity, and hepatic steatosis in high-fat-fed mice. Am. J. Physiol. Gastrointest. Liver Physiol., 2007, 292, G1671-1682.
-
(2007)
Am. J. Physiol. Gastrointest. Liver Physiol.
, vol.292
-
-
Liu, L.F.1
Purushotham, A.2
Wendel, A.A.3
Belury, M.A.4
-
64
-
-
51749099005
-
Dietary single cell protein reduces fatty liver in obese Zucker rats
-
Gudbrandsen, O. A.; Wergedahl, H.; Liaset, B.; Espe, M.; Mørk, S.; Berge, R.K. Dietary single cell protein reduces fatty liver in obese Zucker rats. Br. J. Nutr., 2008, 100, 776-785.
-
(2008)
Br. J. Nutr.
, vol.100
, pp. 776-785
-
-
Gudbrandsen, O.A.1
Wergedahl, H.2
Liaset, B.3
Espe, M.4
Mørk, S.5
Berge, R.K.6
-
65
-
-
24344472642
-
Soy protein reduces hepatic lipotoxicity in hyperinsulinemic obese Zucker fa/fa rats
-
Tovar, A. R.; Torre-Villalvazo, I.; Ochoa, M.; Elías, A.L.; Ortíz, V.; Aguilar-Salinas, C.A.; Torres, N.Soy protein reduces hepatic lipotoxicity in hyperinsulinemic obese Zucker fa/fa rats. J. Lipid Res., 2005, 46, 1823-1832.
-
(2005)
J. Lipid Res.
, vol.46
, pp. 1823-1832
-
-
Tovar, A.R.1
Torre-Villalvazo, I.2
Ochoa, M.3
Elías, A.L.4
Ortíz, V.5
Aguilar-Salinas, C.A.6
Torres, N.7
-
66
-
-
0345601002
-
VLDL metabolism in rats is affected by the concentration and source of dietary protein
-
Madani, S.; Prost, J.; Narce, M.; Belleville, J.VLDL metabolism in rats is affected by the concentration and source of dietary protein. J. Nutr., 2003, 133, 4102-4106.
-
(2003)
J. Nutr.
, vol.133
, pp. 4102-4106
-
-
Madani, S.1
Prost, J.2
Narce, M.3
Belleville, J.4
-
67
-
-
0027087374
-
Depletion of delta 9 desaturase (EC 1.14.99.5) enzyme activity in growing rat during dietary protein restriction
-
Narce, M.; Poisson, J.P.; Belleville, J.; Chanussot, B. Depletion of delta 9 desaturase (EC 1.14.99.5) enzyme activity in growing rat during dietary protein restriction. Br. J. Nutr., 1992, 68, 627-637.
-
(1992)
Br. J. Nutr.
, vol.68
, pp. 627-637
-
-
Narce, M.1
Poisson, J.P.2
Belleville, J.3
Chanussot, B.4
-
68
-
-
33845574569
-
Mice fed a lipogenic methionine-choline-deficient diet develop hypermetabolism coincident with hepatic suppression of SCD-1
-
Rizki, G. L.; Arnaboldi, L.; Gabrielli, B.; Yan, J.; Lee, G.S.; Ng, R.K.; Turner, S.M.; Badger, T.M.; Pitas, R.E.; Maher, J.J. Mice fed a lipogenic methionine-choline-deficient diet develop hypermetabolism coincident with hepatic suppression of SCD-1. J. Lipid Res., 2006, 47, 2280-2290.
-
(2006)
J. Lipid Res.
, vol.47
, pp. 2280-2290
-
-
Rizki, G.L.1
Arnaboldi, L.2
Gabrielli, B.3
Yan, J.4
Lee, G.S.5
Ng, R.K.6
Turner, S.M.7
Badger, T.M.8
Pitas, R.E.9
Maher, J.J.10
-
69
-
-
10044240590
-
Effects of streptozotocin and dietary fructose on delta-6 desaturation in spontaneously hypertensive rat liver
-
Comte, C.; Bellenger, S.; Bellenger, J.; Tessier, C.; Poisson, J.P.; Narce, M. Effects of streptozotocin and dietary fructose on delta-6 desaturation in spontaneously hypertensive rat liver. Biochimie, 2004, 86, 799-806.
-
(2004)
Biochimie
, vol.86
, pp. 799-806
-
-
Comte, C.1
Bellenger, S.2
Bellenger, J.3
Tessier, C.4
Poisson, J.P.5
Narce, M.6
-
70
-
-
79955868038
-
An increase in liver PPARgamma2 is an initial event to induce fatty liver in response to a diet high in butter: PPARgamma2 knockdown improves fatty liver induced by high-saturated fat
-
Yamazaki, T.; Shiraishi, S. et al. An increase in liver PPARgamma2 is an initial event to induce fatty liver in response to a diet high in butter: PPARgamma2 knockdown improves fatty liver induced by high-saturated fat. J. Nutr. Biochem., 2011, 22, 543-553.
-
(2011)
J. Nutr. Biochem.
, vol.22
, pp. 543-553
-
-
Yamazaki, T.1
Shiraishi, S.2
-
71
-
-
34447529373
-
CCAAT/enhancer-binding protein beta deletion reduces adiposity, hepatic steatosis, and diabetes in Lepr(db/db) mice
-
Schroeder-Gloeckler, J. M.; Rahman, S.M.; Janssen, R.C.; Qiao, L.; Shao, J.; Roper, M.; Fischer, S.J.; Lowe, E.; Orlicky, D.J.; McManaman, J.L.; Palmer, C.; Gitomer, W.L.; Huang, W.; O'Doherty, R.M.; Becker, T.C.; Klemm, D.J.; Jensen, D.R.; Pulawa, L.K.; Eckel, R.H.; Friedman, J.E. CCAAT/enhancer-binding protein beta deletion reduces adiposity, hepatic steatosis, and diabetes in Lepr(db/db) mice. J. Biol. Chem., 2007, 282, 15717-15729.
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 15717-15729
-
-
Schroeder-Gloeckler, J.M.1
Rahman, S.M.2
Janssen, R.C.3
Qiao, L.4
Shao, J.5
Roper, M.6
Fischer, S.J.7
Lowe, E.8
Orlicky, D.J.9
McManaman, J.L.10
Palmer, C.11
Gitomer, W.L.12
Huang, W.13
O'Doherty, R.M.14
Becker, T.C.15
Klemm, D.J.16
Jensen, D.R.17
Pulawa, L.K.18
Eckel, R.H.19
Friedman, J.E.20
more..
-
72
-
-
68049099023
-
Metabolic effects of dietary cholesterol in an animal model of insulin resistance and hepatic steatosis
-
Basciano, H.; Miller, A.E.; Naples, M.; Baker, C.; Kohen, R.; Xu. E.; Su, Q.; Allister, E.M.; Wheeler, M.B.; Adeli, K. Metabolic effects of dietary cholesterol in an animal model of insulin resistance and hepatic steatosis. Am. J. Physiol. Endocrinol. Metab., 2009, 297, E462-473.
-
(2009)
Am. J. Physiol. Endocrinol. Metab.
, vol.297
-
-
Basciano, H.1
Miller, A.E.2
Naples, M.3
Baker, C.4
Kohen, R.5
Xu, E.6
Su, Q.7
Allister, E.M.8
Wheeler, M.B.9
Adeli, K.10
-
73
-
-
68949091995
-
Role of adenosine monophosphate-activated protein kinase-p70 ribosomal S6 kinase-1 pathway in repression of liver X receptor-alpha-dependent lipogenic gene induction and hepatic steatosis by a novel class of dithiolethiones
-
Hwahng, S. H.; Ki, S.H.; Bae, E.J.; Kim, H.E.; Kim, S.G. Role of adenosine monophosphate-activated protein kinase-p70 ribosomal S6 kinase-1 pathway in repression of liver X receptor-alpha-dependent lipogenic gene induction and hepatic steatosis by a novel class of dithiolethiones. Hepatology, 2009, 49, 1913-1925.
-
(2009)
Hepatology
, vol.49
, pp. 1913-1925
-
-
Hwahng, S.H.1
Ki, S.H.2
Bae, E.J.3
Kim, H.E.4
Kim, S.G.5
-
74
-
-
39749098685
-
PXR and LXR in hepatic steatosis, a new dog and an old dog with new tricks
-
Lee, J. H., Zhou J, Xie W. PXR and LXR in hepatic steatosis, a new dog and an old dog with new tricks. Mol. Pharm., 2008, 5, 60-66.
-
(2008)
Mol. Pharm.
, vol.5
, pp. 60-66
-
-
Lee, J.H.1
Zhou, J.2
Xie, W.3
-
75
-
-
34247093820
-
T0901317 is a potent PXR ligand: Implications for the biology ascribed to LXR
-
Mitro, N.; Vargas, L.; Romeo, R.; Koder, A.; Saez, E.T0901317 is a potent PXR ligand: implications for the biology ascribed to LXR. FEBS Lett., 2007, 581, 1721-1726.
-
(2007)
FEBS Lett.
, vol.581
, pp. 1721-1726
-
-
Mitro, N.1
Vargas, L.2
Romeo, R.3
Koder, A.4
Saez, E.5
-
76
-
-
80051686720
-
ATF4 deficiency protects mice from high-carbohyd.rate diet-induced liver steatosis
-
Li, H.; Meng, Q.; Xiao, F.; Chen, S.; Du, Y.; Yu, J.; Wang, C.; Guo, F. ATF4 deficiency protects mice from high-carbohyd.rate diet-induced liver steatosis. Biochem. J., 2011, 438, 283-289.
-
(2011)
Biochem. J.
, vol.438
, pp. 283-289
-
-
Li, H.1
Meng, Q.2
Xiao, F.3
Chen, S.4
Du, Y.5
Yu, J.6
Wang, C.7
Guo, F.8
-
77
-
-
18044388542
-
Stearoyl-CoA desaturase as a new drug target for obesity treatment
-
Dobrzyn, A.; Ntambi, J. M. Stearoyl-CoA desaturase as a new drug target for obesity treatment. Obes. Rev., 2005, 6, 169-174.
-
(2005)
Obes. Rev.
, vol.6
, pp. 169-174
-
-
Dobrzyn, A.1
Ntambi, J.M.2
-
78
-
-
69949176746
-
Stearoyl-CoA desaturase inhibitors: Update on patented compounds
-
Liu, G. Stearoyl-CoA desaturase inhibitors: update on patented compounds. Expert Opin. Ther. Pat., 2009, 19, 1169-1191.
-
(2009)
Expert Opin. Ther. Pat.
, vol.19
, pp. 1169-1191
-
-
Liu, G.1
-
79
-
-
77952561929
-
Novel substituted heteroaromatic compounds as inhibitors of stearoyl-CoA desaturase
-
Dobrzyn, P.; Dobrzyn, A. Novel substituted heteroaromatic compounds as inhibitors of stearoyl-CoA desaturase. Expert Opin. Ther. Pat., 2010, 20, 849-853.
-
(2010)
Expert Opin. Ther. Pat.
, vol.20
, pp. 849-853
-
-
Dobrzyn, P.1
Dobrzyn, A.2
-
80
-
-
34948895555
-
Cideb regulates diet-induced obesity, liver steatosis, and insulin sensitivity by controlling lipogenesis and fatty acid oxidation
-
Li, J. Z.; Ye, J.; Xue, B.; Qi, J.; Zhang, J.; Zhou, Z.; Li, Q.; Wen, Z.; Li, P.; Cideb regulates diet-induced obesity, liver steatosis, and insulin sensitivity by controlling lipogenesis and fatty acid oxidation. Diabetes, 2007, 56, 2523-2532.
-
(2007)
Diabetes
, vol.56
, pp. 2523-2532
-
-
Li, J.Z.1
Ye, J.2
Xue, B.3
Qi, J.4
Zhang, J.5
Zhou, Z.6
Li, Q.7
Wen, Z.8
Li, P.9
-
81
-
-
37449000478
-
The cannabinoid CB1 receptor antagonist SR141716A (Rimonabant) enhances the metabolic benefits of long-term treatment with oleoylethanolamide in Zucker rats
-
Serrano, A.; Del Arco, I.; Javier, P.F.; Macías, M.; Perez-Valero, V.; Rodríguez de Fonseca, F. The cannabinoid CB1 receptor antagonist SR141716A (Rimonabant) enhances the metabolic benefits of long-term treatment with oleoylethanolamide in Zucker rats. Neuropharmacology, 2008, 54, 226-234.
-
(2008)
Neuropharmacology
, vol.54
, pp. 226-234
-
-
Serrano, A.1
Del Arco, I.2
Javier, P.F.3
MacÍas, M.4
Perez-Valero, V.5
Rodríguez De Fonseca, F.6
-
82
-
-
77952426387
-
Stearoyl-coenzyme A desaturase 1 inhibition and the metabolic syndrome: Considerations for future drug discovery
-
Brown, J. M.; Rudel, L. L. Stearoyl-coenzyme A desaturase 1 inhibition and the metabolic syndrome: considerations for future drug discovery. Curr. Opin. Lipidol., 2010, 21, 192-197.
-
(2010)
Curr. Opin. Lipidol.
, vol.21
, pp. 192-197
-
-
Brown, J.M.1
Rudel, L.L.2
-
83
-
-
33644919989
-
Early diet-induced non-alcoholic steatohepatitis in APOE2 knock-in mice and its prevention by fibrates
-
Shiri-Sverdlov, R.; Wouters, K.; van Gorp, P.J.; Gijbels, M.J.; Noel, B.; Buffat, L.; Staels, B.; Maeda, N.; van Bilsen, M.; Hofker, M.H. Early diet-induced non-alcoholic steatohepatitis in APOE2 knock-in mice and its prevention by fibrates. J. Hepatol., 2006, 44, 732-741.
-
(2006)
J. Hepatol.
, vol.44
, pp. 732-741
-
-
Shiri-Sverdlov, R.1
Wouters, K.2
Van Gorp, P.J.3
Gijbels, M.J.4
Noel, B.5
Buffat, L.6
Staels, B.7
Maeda, N.8
Van Bilsen, M.9
Hofker, M.H.10
-
84
-
-
45549107634
-
Serum fatty acid composition and indices of stearoyl-CoA desaturase activity are associated with systemic inflammation: Longitudinal analyses in middle-aged men
-
Petersson, H.; Basu. S.; Cederholm, T.; Risérus, U. Serum fatty acid composition and indices of stearoyl-CoA desaturase activity are associated with systemic inflammation: longitudinal analyses in middle-aged men. Br. J. Nutr., 2008, 99, 1186-1189.
-
(2008)
Br. J. Nutr.
, vol.99
, pp. 1186-1189
-
-
Petersson, H.1
Basu, S.2
Cederholm, T.3
Risérus, U.4
-
85
-
-
58649105336
-
Tissue inhibitor of metalloproteinase 3 deficiency causes hepatic steatosis and adipose tissue inflammation in mice
-
Menghini, R.; Menini, S.; Amoruso, R.; Fiorentino, L.; Casagrande, V.; Marzano, V.; Tornei, F.; Bertucci, P.; Iacobini, C.; Serino, M.; Porzio, O.; Hribal, M.L.; Folli, F.; Khokha, R.; Urbani, A.; Lauro, R.; Pugliese, G.; Federici, M. Tissue inhibitor of metalloproteinase 3 deficiency causes hepatic steatosis and adipose tissue inflammation in mice. Gastroenterology, 2009, 136, 663-672
-
(2009)
Gastroenterology
, vol.136
, pp. 663-672
-
-
Menghini, R.1
Menini, S.2
Amoruso, R.3
Fiorentino, L.4
Casagrande, V.5
Marzano, V.6
Tornei, F.7
Bertucci, P.8
Iacobini, C.9
Serino, M.10
Porzio, O.11
Hribal, M.L.12
Folli, F.13
Khokha, R.14
Urbani, A.15
Lauro, R.16
Pugliese, G.17
Federici, M.18
-
86
-
-
73349117487
-
Toll-like receptor signaling links dietary fatty acids to the metabolic syndrome
-
Fessler, M. B.; Rudell L.L.; Brown, J.M. Toll-like receptor signaling links dietary fatty acids to the metabolic syndrome. Curr. Opin. Lipidol., 2009, 20, 379-385.
-
(2009)
Curr. Opin. Lipidol.
, vol.20
, pp. 379-385
-
-
Fessler, M.B.1
Rudell, L.L.2
Brown, J.M.3
-
87
-
-
38649128825
-
Metabolomics reveals that hepatic stearoyl-CoA desaturase 1 downregulation exacerbates inflammation and acute colitis
-
Chen, C.; Shah, Y.M.; Morimura, K.; Krausz, K.W.; Miyazaki, M.; Richardson, T.A.; Morgan, E.T.; Ntambi, J.M.; Idle, J.R.; Gonzalez, F.J. Metabolomics reveals that hepatic stearoyl-CoA desaturase 1 downregulation exacerbates inflammation and acute colitis. Cell. Metab., 2008, 7, 135-147.
-
(2008)
Cell. Metab.
, vol.7
, pp. 135-147
-
-
Chen, C.1
Shah, Y.M.2
Morimura, K.3
Krausz, K.W.4
Miyazaki, M.5
Richardson, T.A.6
Morgan, E.T.7
Ntambi, J.M.8
Idle, J.R.9
Gonzalez, F.J.10
-
88
-
-
84860780829
-
Distinct regulation of stearoyl-CoA desaturase 1 gene expression by cis and trans C18:1 fatty acids in human aortic smooth muscle cells
-
Minville-Walz, M.; Gresti, J.; Pichon, L.; Bellenger, S.; Bellenger, J.; Narce, M.; Rialland, M. Distinct regulation of stearoyl-CoA desaturase 1 gene expression by cis and trans C18:1 fatty acids in human aortic smooth muscle cells. Genes Nutr. 2012, 7, :209-216.
-
(2012)
Genes Nutr
, vol.7
, pp. 209-216
-
-
Minville-Walz, M.1
Gresti, J.2
Pichon, L.3
Bellenger, S.4
Bellenger, J.5
Narce, M.6
Rialland, M.7
-
89
-
-
73849108138
-
Loss of Stearoyl-CoA desaturase-1 attenuates adipocyte inflammation: Effects. of adipocyte-derived oleate
-
Liu, X.; Miyazaki, M.; Flowers, M.T.; Sampath, H.; Zhao, M.; Chu, K.; Paton, C.M.; Joo, D.S.; Ntambi, J.M. Loss of Stearoyl-CoA desaturase-1 attenuates adipocyte inflammation: effects. of adipocyte-derived oleate. Arterioscler. Thromb. Vasc. Biol., 2010, 30, 31-38.
-
(2010)
Arterioscler. Thromb. Vasc. Biol.
, vol.30
, pp. 31-38
-
-
Liu, X.1
Miyazaki, M.2
Flowers, M.T.3
Sampath, H.4
Zhao, M.5
Chu, K.6
Paton, C.M.7
Joo, D.S.8
Ntambi, J.M.9
-
90
-
-
63149192855
-
Quantitative lipid metabolomic changes in alcoholic micropigs with fatty liver disease
-
Zivkovic, A.; Bruce, M.; German, J.; Esfandiari, F.; Halsted, C.H. Quantitative lipid metabolomic changes in alcoholic micropigs with fatty liver disease. Alcohol. Clin. Exp. Res., 2009, 33, 751-758.
-
(2009)
Alcohol. Clin. Exp. Res.
, vol.33
, pp. 751-758
-
-
Zivkovic, A.1
Bruce, M.2
German, J.3
Esfandiari, F.4
Halsted, C.H.5
-
91
-
-
0034878909
-
Effect of ethanol on polyunsaturated fatty acid biosynthesis in hepatocytes from spontaneously hypertensive rats
-
Narce, M.; Poisson, J.P.; Bellenger, J.; Bellenger, S. Effect of ethanol on polyunsaturated fatty acid biosynthesis in hepatocytes from spontaneously hypertensive rats. Alcohol. Clin. Exp. Res., 2001, 25, 1231-1237.
-
(2001)
Alcohol. Clin. Exp. Res.
, vol.25
, pp. 1231-1237
-
-
Narce, M.1
Poisson, J.P.2
Bellenger, J.3
Bellenger, S.4
-
92
-
-
10744221756
-
Pioglitazone prevents alcohol-induced fatty liver in rats through upregulation of c-Met
-
Tomita, K.; Azuma, T.; Kitamura, N.; Nishida, J.; Tamiya, G.; Oka, A.; Inokuchi, S.; Nishimura, T.; Suematsu, M.; Ishii, H. Pioglitazone prevents alcohol-induced fatty liver in rats through upregulation of c-Met. Gastroenterology, 2004, 126, 873-885.
-
(2004)
Gastroenterology
, vol.126
, pp. 873-885
-
-
Tomita, K.1
Azuma, T.2
Kitamura, N.3
Nishida, J.4
Tamiya, G.5
Oka, A.6
Inokuchi, S.7
Nishimura, T.8
Suematsu, M.9
Ishii, H.10
-
93
-
-
21744436422
-
Chronic ethanol feeding and folate deficiency activate hepatic endoplasmic reticulum stress pathway in micropigs
-
Esfandiari, F.; Villanueva, J.A.; Wong, D.H.; French, S.W.; Halsted, C.H. Chronic ethanol feeding and folate deficiency activate hepatic endoplasmic reticulum stress pathway in micropigs. Am. J. Physiol. Gastrointest. Liver Physiol., 2005, 289, G54-63.
-
(2005)
Am. J. Physiol. Gastrointest. Liver Physiol.
, vol.289
-
-
Esfandiari, F.1
Villanueva, J.A.2
Wong, D.H.3
French, S.W.4
Halsted, C.H.5
-
94
-
-
0037047284
-
Ethanol induces fatty acid synthesis pathways by activation of sterol regulatory element-binding protein (SREBP)
-
You, M.; Fischer, M.; Deeg, M.A.; Crabb, D.W. Ethanol induces fatty acid synthesis pathways by activation of sterol regulatory element-binding protein (SREBP). J. Biol. Chem., 2002, 277, 29342-29347.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 29342-29347
-
-
You, M.1
Fischer, M.2
Deeg, M.A.3
Crabb, D.W.4
-
95
-
-
33749253713
-
Predominant role of sterol response element binding proteins (SREBP) lipogenic pathways in hepatic steatosis in the murine intragastric ethanol feeding model
-
Ji, C.; Chan, C.; Kaplowitz, N. Predominant role of sterol response element binding proteins (SREBP) lipogenic pathways in hepatic steatosis in the murine intragastric ethanol feeding model. J. Hepatol., 2006, 45, 717-724.
-
(2006)
J. Hepatol.
, vol.45
, pp. 717-724
-
-
Ji, C.1
Chan, C.2
Kaplowitz, N.3
-
96
-
-
34548511145
-
Differential gene expression and lipid metabolism in fatty liver induced by acute ethanol treatment in mice
-
Yin, H.; Kim, M.; Kim, J.H.; Kong, G.; Kang, K.S.; Kim, H.L.; Yoon, B.I.; Lee, M.O.; Lee, B.H. Differential gene expression and lipid metabolism in fatty liver induced by acute ethanol treatment in mice. Toxicol. Appl. Pharmacol., 2007, 223, 225-233.
-
(2007)
Toxicol. Appl. Pharmacol.
, vol.223
, pp. 225-233
-
-
Yin, H.1
Kim, M.2
Kim, J.H.3
Kong, G.4
Kang, K.S.5
Kim, H.L.6
Yoon, B.I.7
Lee, M.O.8
Lee, B.H.9
-
97
-
-
9644290860
-
The role of AMP-activated protein kinase in the action of ethanol in the liver
-
You, M.; Matsumoto, M.; Pacold, C.M.; Cho, W.K.; Crabb, D.W. The role of AMP-activated protein kinase in the action of ethanol in the liver. Gastroenterology, 2004,127, 1798-1808.
-
(2004)
Gastroenterology
, vol.127
, pp. 1798-1808
-
-
You, M.1
Matsumoto, M.2
Pacold, C.M.3
Cho, W.K.4
Crabb, D.W.5
-
98
-
-
0037378516
-
Coactivator-dependent acetylation stabilizes members of the SREBP family of transcription factors
-
Giandomenico, V.; Simonsson, M.; Grönroos, E.; Ericsson, J. Coactivator-dependent acetylation stabilizes members of the SREBP family of transcription factors. Mol. Cell. Biol., 2003, 23, 2587-2599
-
(2003)
Mol. Cell. Biol.
, vol.23
, pp. 2587-2599
-
-
Giandomenico, V.1
Simonsson, M.2
Grönroos, E.3
Ericsson, J.4
-
99
-
-
4444349833
-
Selective coactivator interactions in gene activation by SREBP-1a and -1c
-
Toth, J. I.; Datta, S.; Athanikar, J.N.; Freedman, L.P.; Osborne, T.F. Selective coactivator interactions in gene activation by SREBP-1a and -1c. Mol. Cell. Biol., 2004, 24, 8288-8300.
-
(2004)
Mol. Cell. Biol.
, vol.24
, pp. 8288-8300
-
-
Toth, J.I.1
Datta, S.2
Athanikar, J.N.3
Freedman, L.P.4
Osborne, T.F.5
-
100
-
-
42049113608
-
Involvement of mammalian sirtuin 1 in the action of ethanol in the liver
-
You, M.; Liang, X.; Ajmo, J.M.; Ness, G.C. Involvement of mammalian sirtuin 1 in the action of ethanol in the liver. Am. J. Physiol. Gastrointest. Liver Physiol., 2008, 294, G892-898.
-
(2008)
Am. J. Physiol. Gastrointest. Liver Physiol.
, vol.294
-
-
You, M.1
Liang, X.2
Ajmo, J.M.3
Ness, G.C.4
-
101
-
-
40449093056
-
Mammalian sirtuin 1 is involved in the protective action of dietary saturated fat against alcoholic fatty liver in mice
-
You, M.; Cao, Q.; Liang, X.; Ajmo, J.M.; Ness, G.C. Mammalian sirtuin 1 is involved in the protective action of dietary saturated fat against alcoholic fatty liver in mice. J. Nutr., 2008, 138, 497-501.
-
(2008)
J. Nutr.
, vol.138
, pp. 497-501
-
-
You, M.1
Cao, Q.2
Liang, X.3
Ajmo, J.M.4
Ness, G.C.5
-
102
-
-
41349098793
-
Cell type-dependent pro- and anti-inflammatory role of signal transducer and activator of transcription 3 in alcoholic liver injury
-
Horiguchi, N.; Wang, L.; Mukhopadhyay, P.; Park, O.; Jeong, W.I.; Lafdil, F.; Osei-Hyiaman, D.; Moh, A.; Fu, X.Y.; Pacher, P.; Kunos, G.; Gao, B. Cell type-dependent pro- and anti-inflammatory role of signal transducer and activator of transcription 3 in alcoholic liver injury. Gastroenterology, 2008, 134, 1148-1158.
-
(2008)
Gastroenterology
, vol.134
, pp. 1148-1158
-
-
Horiguchi, N.1
Wang, L.2
Mukhopadhyay, P.3
Park, O.4
Jeong, W.I.5
Lafdil, F.6
Osei-Hyiaman, D.7
Moh, A.8
Fu, X.Y.9
Pacher, P.10
Kunos, G.11
Gao, B.12
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