-
1
-
-
0037048669
-
Prevalence and trends in obesity among US adults, 1999-2000
-
Flegal KM, Carroll MD, Ogden CL, Johnson CL. Prevalence and trends in obesity among US adults, 1999-2000. J Amer Med Assoc 2002; 288: 1723-1727.
-
(2002)
J Amer Med Assoc
, vol.288
, pp. 1723-1727
-
-
Flegal, K.M.1
Carroll, M.D.2
Ogden, C.L.3
Johnson, C.L.4
-
2
-
-
0023878441
-
Body mass index and mortality among nonsmoking older persons. The framingham heart study
-
Harris T, Cook EF, Garrison R, Higgins M, Kannel W, Goldman L. Body mass index and mortality among nonsmoking older persons. The framingham heart study. J Amer Med Assoc 1988; 259: 1520-1524.
-
(1988)
J Amer Med Assoc
, vol.259
, pp. 1520-1524
-
-
Harris, T.1
Cook, E.F.2
Garrison, R.3
Higgins, M.4
Kannel, W.5
Goldman, L.6
-
3
-
-
0034611791
-
Obesity as a medical problem
-
Kopelman PG. Obesity as a medical problem. Nature 2000; 404: 635-643.
-
(2000)
Nature
, vol.404
, pp. 635-643
-
-
Kopelman, P.G.1
-
4
-
-
2942716780
-
Modern science versus the stigma of obesity
-
Friedman JM. Modern science versus the stigma of obesity. Nat Med 2004; 10: 563-569.
-
(2004)
Nat Med
, vol.10
, pp. 563-569
-
-
Friedman, J.M.1
-
5
-
-
0036896505
-
Malonyl-CoA signaling, lipid partitioning, and glucolipotoxicity: Role in beta-cell adaptation and failure in the etiology of diabetes
-
Prentki M, Joly E, El-Assaad W, Roduit R. Malonyl-CoA signaling, lipid partitioning, and glucolipotoxicity: role in beta-cell adaptation and failure in the etiology of diabetes. Diabetes 2002; 51: S405-S413.
-
(2002)
Diabetes
, vol.51
-
-
Prentki, M.1
Joly, E.2
El-Assaad, W.3
Roduit, R.4
-
6
-
-
0037328928
-
Malonyl-CoA and AMP-activated protein kinase (AMPK): Possible links between insulin resistance in muscle and early endothelial cell damage in diabetes
-
Ruderman NB, Cacicedo JM, Itani S, Yagihashi N, Saha AK, Ye JM, Chen K, Zou M, Carling D, Boden G, Cohen RA, Keaney J, Kraegen EW, Ido Y. Malonyl-CoA and AMP-activated protein kinase (AMPK): possible links between insulin resistance in muscle and early endothelial cell damage in diabetes. Biochem Soc Trans 2003; 31: 202-206.
-
(2003)
Biochem Soc Trans
, vol.31
, pp. 202-206
-
-
Ruderman, N.B.1
Cacicedo, J.M.2
Itani, S.3
Yagihashi, N.4
Saha, A.K.5
Ye, J.M.6
Chen, K.7
Zou, M.8
Carling, D.9
Boden, G.10
Cohen, R.A.11
Keaney, J.12
Kraegen, E.W.13
Ido, Y.14
-
7
-
-
0036092239
-
Banting lecture 2001: Dysregulation of fatty acid metabolism in the etiology of type 2 diabetes
-
McGarry JD. Banting lecture 2001: dysregulation of fatty acid metabolism in the etiology of type 2 diabetes. Diabetes 2002; 51: 7-18.
-
(2002)
Diabetes
, vol.51
, pp. 7-18
-
-
McGarry, J.D.1
-
8
-
-
0036182137
-
Lipotoxic diseases
-
Unger RH. Lipotoxic diseases. Annu Rev Med 2002; 53: 319-336.
-
(2002)
Annu Rev Med
, vol.53
, pp. 319-336
-
-
Unger, R.H.1
-
9
-
-
0027947379
-
Beta-cell lipotoxicity in the pathogenesis of non-insulin-dependent diabetes mellitus of obese rats: Impairment in adipocyte-beta-cell relationships
-
Lee Y, Hirose H, Ohneda M, Johnson JH, McGarry JD, Unger RH. Beta-cell lipotoxicity in the pathogenesis of non-insulin-dependent diabetes mellitus of obese rats: impairment in adipocyte-beta-cell relationships. Proc Natl Acad Sci USA 1994; 91: 10878-10882.
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, pp. 10878-10882
-
-
Lee, Y.1
Hirose, H.2
Ohneda, M.3
Johnson, J.H.4
McGarry, J.D.5
Unger, R.H.6
-
10
-
-
0345374579
-
Minireview: Weapons of lean body mass destruction: The role of ectopic lipids in the metabolic syndrome
-
Unger RH. Minireview: weapons of lean body mass destruction: the role of ectopic lipids in the metabolic syndrome. Endocrinology 2003; 144: 5159-5165.
-
(2003)
Endocrinology
, vol.144
, pp. 5159-5165
-
-
Unger, R.H.1
-
11
-
-
0029077405
-
The regulation of stearoyl-CoA desaturase (SCD)
-
Ntambi JM. The regulation of stearoyl-CoA desaturase (SCD). Prog Lipid Res 1995; 34: 139-150.
-
(1995)
Prog Lipid Res
, vol.34
, pp. 139-150
-
-
Ntambi, J.M.1
-
12
-
-
0028846540
-
Diets rich in eicosapentaenoic acid and gamma-linolenic acid affect phospholipid fatty acid composition and production of prostaglandins E1, E2 and E3 in turbot (Scophthalmus maximus), a species deficient in delta 5 fatty acid desaturase
-
Bell JG, Tocher DR, MacDonald FM, Sargent JR. Diets rich in eicosapentaenoic acid and gamma-linolenic acid affect phospholipid fatty acid composition and production of prostaglandins E1, E2 and E3 in turbot (Scophthalmus maximus), a species deficient in delta 5 fatty acid desaturase. Prostaglandins Leukot Essent Fatty Acids 1995; 53: 279-286.
-
(1995)
Prostaglandins Leukot Essent Fatty Acids
, vol.53
, pp. 279-286
-
-
Bell, J.G.1
Tocher, D.R.2
MacDonald, F.M.3
Sargent, J.R.4
-
13
-
-
0036911046
-
Lack of stearoyl-CoA desaturase-1 function induces a palmitoyl-CoA Delta6 desaturase and represses the stearoyl-CoA desaturase-3 gene in the preputial glands of the mouse
-
Miyazaki M, Gomez FE, Ntambi JM. Lack of stearoyl-CoA desaturase-1 function induces a palmitoyl-CoA Delta6 desaturase and represses the stearoyl-CoA desaturase-3 gene in the preputial glands of the mouse. J Lipid Res 2002; 43: 2146-2154.
-
(2002)
J Lipid Res
, vol.43
, pp. 2146-2154
-
-
Miyazaki, M.1
Gomez, F.E.2
Ntambi, J.M.3
-
14
-
-
0026504882
-
Postnatal dietary fat influences mRNAS involved in myelination
-
DeWille JW, Farmer SJ. Postnatal dietary fat influences mRNAS involved in myelination. Dev Neurosci 1992; 14: 61-68.
-
(1992)
Dev Neurosci
, vol.14
, pp. 61-68
-
-
DeWille, J.W.1
Farmer, S.J.2
-
15
-
-
0033058904
-
Selective activation of phospholipase D2 by unsaturated fatty acid
-
Kim JH, Kim Y, Lee SD. Selective activation of phospholipase D2 by unsaturated fatty acid. FEBS Lett 1999; 454: 42-46.
-
(1999)
FEBS Lett
, vol.454
, pp. 42-46
-
-
Kim, J.H.1
Kim, Y.2
Lee, S.D.3
-
16
-
-
0032871502
-
Regulation of stearoyl-CoA desaturese by polyunsaturated fatty acids and cholesterol
-
Ntambi JM. Regulation of stearoyl-CoA desaturese by polyunsaturated fatty acids and cholesterol. J Lipid Res 1999; 40: 1549-1558.
-
(1999)
J Lipid Res
, vol.40
, pp. 1549-1558
-
-
Ntambi, J.M.1
-
17
-
-
0032862130
-
Palmitate and oleate induce the immediate-early response genes c-fos and nur-77 in the pancreatic beta-cell line INS-1
-
Roche E, Buteau J, Aniento I, Reig JA, Soria B, Prentki M. Palmitate and oleate induce the immediate-early response genes c-fos and nur-77 in the pancreatic beta-cell line INS-1. Diabetes 1999; 48: 2007-2014.
-
(1999)
Diabetes
, vol.48
, pp. 2007-2014
-
-
Roche, E.1
Buteau, J.2
Aniento, I.3
Reig, J.A.4
Soria, B.5
Prentki, M.6
-
18
-
-
0036885053
-
Elevation of oleate-activated phospholipase D activity during thymic atrophy
-
Lee Y, Song SM, Park HS, Kim S, Koh EH, Choi MS, Choi MU. Elevation of oleate-activated phospholipase D activity during thymic atrophy. Immunology 2002; 107: 435-443.
-
(2002)
Immunology
, vol.107
, pp. 435-443
-
-
Lee, Y.1
Song, S.M.2
Park, H.S.3
Kim, S.4
Koh, E.H.5
Choi, M.S.6
Choi, M.U.7
-
19
-
-
0037453056
-
Triglyceride accumulation protects against fatty acid-induced lipotoxicity
-
Listenberger LL, Han X, Lewis SE, Cases S, Farese RV Jr, Ory DS, Schaffer JE. Triglyceride accumulation protects against fatty acid-induced lipotoxicity. Proc Natl Acad Sci USA 2003; 100: 3077-3082.
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 3077-3082
-
-
Listenberger, L.L.1
Han, X.2
Lewis, S.E.3
Cases, S.4
Farese Jr., R.V.5
Ory, D.S.6
Schaffer, J.E.7
-
20
-
-
0037832581
-
Recent insights into stearoyl-CoA desaturase-1
-
Ntambi JM, Miyazaki M. Recent insights into stearoyl-CoA desaturase-1. Curr Opin Lipidol 2003; 14: 255-261.
-
(2003)
Curr Opin Lipidol
, vol.14
, pp. 255-261
-
-
Ntambi, J.M.1
Miyazaki, M.2
-
21
-
-
1542404084
-
The role of stearoyl-CoA desaturase in body weight regulation
-
Dobrzyn A, Ntambi JM. The role of stearoyl-CoA desaturase in body weight regulation. Trends Cardiovasc Med 2004; 14: 77-81.
-
(2004)
Trends Cardiovasc Med
, vol.14
, pp. 77-81
-
-
Dobrzyn, A.1
Ntambi, J.M.2
-
22
-
-
2342652187
-
Stearoyl-CoA desaturase 1 deficiency increases fatty acid oxidation by activating AMP-activated protein kinase in liver
-
Dobrzyn P, Dobrzyn A, Miyazaki M, Cohen P, Asilmaz E, Hardie DG, Friedman JM, Ntambi JM. Stearoyl-CoA desaturase 1 deficiency increases fatty acid oxidation by activating AMP-activated protein kinase in liver. Proc Natl Acad Sci USA 2004; 101: 6409-6414.
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 6409-6414
-
-
Dobrzyn, P.1
Dobrzyn, A.2
Miyazaki, M.3
Cohen, P.4
Asilmaz, E.5
Hardie, D.G.6
Friedman, J.M.7
Ntambi, J.M.8
-
23
-
-
0033563109
-
Human stearoyl-CoA desaturase: Alternative transcripts generated from a single gene by usage of tandem polyadenylation sites
-
Zhang L, Ge L, Parimoo S, Stenn K, Prouty SM. Human stearoyl-CoA desaturase: alternative transcripts generated from a single gene by usage of tandem polyadenylation sites. Biochem J 1999; 340: 255-264.
-
(1999)
Biochem J
, vol.340
, pp. 255-264
-
-
Zhang, L.1
Ge, L.2
Parimoo, S.3
Stenn, K.4
Prouty, S.M.5
-
24
-
-
0037464551
-
Identification and characterization of a novel gene disrupted by a pericentric inversion inv(4)(p13.1q21.1) in a family with cleft lip
-
Beiraghi S, Zhou M, Talmadge CB, Went-Sumegi N, Davis JR, Huang D, Saal H, Seemayer TA, Sumegi J. Identification and characterization of a novel gene disrupted by a pericentric inversion inv(4)(p13.1q21.1) in a family with cleft lip. Gene 2003; 309: 11-21.
-
(2003)
Gene
, vol.309
, pp. 11-21
-
-
Beiraghi, S.1
Zhou, M.2
Talmadge, C.B.3
Went-Sumegi, N.4
Davis, J.R.5
Huang, D.6
Saal, H.7
Seemayer, T.A.8
Sumegi, J.9
-
25
-
-
0037067570
-
Role for stearoyl-CoA desaturase-1 in leptin-mediated weight loss
-
Cohen P, Miyazaki M, Socci ND, Hagge-Greenberg A, Liedtke W, Soukas AA, Sharma R, Hudgins LC, Ntambi JM, Friedman JM. Role for stearoyl-CoA desaturase-1 in leptin-mediated weight loss. Science 2002; 297: 240-243.
-
(2002)
Science
, vol.297
, pp. 240-243
-
-
Cohen, P.1
Miyazaki, M.2
Socci, N.D.3
Hagge-Greenberg, A.4
Liedtke, W.5
Soukas, A.A.6
Sharma, R.7
Hudgins, L.C.8
Ntambi, J.M.9
Friedman, J.M.10
-
26
-
-
0037143752
-
Loss of stearoyl-CoA desaturase-1 function protects mice against adiposity
-
Ntambi JM, Miyazaki M, Stoehr JP, Lan H, Kendziorski CM, Yandell BS, Song Y, Cohen P, Friedman JM, Attie AD. Loss of stearoyl-CoA desaturase-1 function protects mice against adiposity. Proc Natl Acad Sci USA 2002; 99: 11482-11486.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 11482-11486
-
-
Ntambi, J.M.1
Miyazaki, M.2
Stoehr, J.P.3
Lan, H.4
Kendziorski, C.M.5
Yandell, B.S.6
Song, Y.7
Cohen, P.8
Friedman, J.M.9
Attie, A.D.10
-
27
-
-
4644340815
-
Lack of stearoyl-CoA desaturase 1 upregulates basal thermogenesis, but causes hypothermia in cold environment
-
Lee SH, Dobrzyn A, Dobrzyn P, Rahman SM, Miyazaki M, Ntambi JM. Lack of stearoyl-CoA desaturase 1 upregulates basal thermogenesis, but causes hypothermia in cold environment. J Lipid Res 2004; 45: 1674-1682.
-
(2004)
J Lipid Res
, vol.45
, pp. 1674-1682
-
-
Lee, S.H.1
Dobrzyn, A.2
Dobrzyn, P.3
Rahman, S.M.4
Miyazaki, M.5
Ntambi, J.M.6
-
28
-
-
0141813781
-
Stearoyl-CoA desaturase 1 deficiency elevates insulin-signaling components and down-regulates protein-tyrosine phosphatase 1B in muscle
-
Rahman SM, Dobrzyn A, Dobrzyn P, Lee SH, Miyazaki M, Ntambi JM. Stearoyl-CoA desaturase 1 deficiency elevates insulin-signaling components and down-regulates protein-tyrosine phosphatase 1B in muscle. Proc Natl Acad Sci USA 2003; 100: 11110-11115.
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 11110-11115
-
-
Rahman, S.M.1
Dobrzyn, A.2
Dobrzyn, P.3
Lee, S.H.4
Miyazaki, M.5
Ntambi, J.M.6
-
29
-
-
0035970805
-
Continuous fatty acid oxidation and reduced fat storage in mice lacking acetyl-CoA carboxylase 2
-
Abu-Elheiga L, Matzuk MM, Abo-Hashema KA, Wakil SJ. Continuous fatty acid oxidation and reduced fat storage in mice lacking acetyl-CoA carboxylase 2. Science 2001; 291: 2613-2616.
-
(2001)
Science
, vol.291
, pp. 2613-2616
-
-
Abu-Elheiga, L.1
Matzuk, M.M.2
Abo-Hashema, K.A.3
Wakil, S.J.4
-
30
-
-
0034733730
-
Reduced food intake and body weight in mice treated with fatty acid synthase inhibitors
-
Loftus TM, Jaworsky DE, Frehywot GL, Townsend CA, Ronnett GV, Lane MD, Kuhajda FP. Reduced food intake and body weight in mice treated with fatty acid synthase inhibitors. Science 2000; 288: 2379-2381.
-
(2000)
Science
, vol.288
, pp. 2379-2381
-
-
Loftus, T.M.1
Jaworsky, D.E.2
Frehywot, G.L.3
Townsend, C.A.4
Ronnett, G.V.5
Lane, M.D.6
Kuhajda, F.P.7
-
31
-
-
0037047112
-
C75 increases peripheral energy utilization and fatty acid oxidation in diet-induced obesity
-
Thupari JN, Landree LE, Ronnett GV, Kuhajda FP. C75 increases peripheral energy utilization and fatty acid oxidation in diet-induced obesity. Proc Natl Acad Sci USA 2002; 99: 9498-9502.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 9498-9502
-
-
Thupari, J.N.1
Landree, L.E.2
Ronnett, G.V.3
Kuhajda, F.P.4
-
32
-
-
0034103658
-
Obesity resistance and multiple mechanisms of triglyceride synthesis in mice lacking Dgat
-
Smith SJ, Cases S, Jensen DR, Chen HC, Sande E, Tow B, Sanan DA, Raber J, Eckel RH, Farese RV Jr. Obesity resistance and multiple mechanisms of triglyceride synthesis in mice lacking Dgat. Nat Genet 2000; 25: 87-90.
-
(2000)
Nat Genet
, vol.25
, pp. 87-90
-
-
Smith, S.J.1
Cases, S.2
Jensen, D.R.3
Chen, H.C.4
Sande, E.5
Tow, B.6
Sanan, D.A.7
Raber, J.8
Eckel, R.H.9
Farese Jr., R.V.10
-
33
-
-
0023851885
-
Reduced rate of energy expenditure as a risk factor for body-weight gain
-
Ravussin E, Lillioja S, Knowler WC, Christin L, Freymond D, Abbott WG, Boyce V, Howard BV, Bogardus C. Reduced rate of energy expenditure as a risk factor for body-weight gain. N Engl J Med 1988; 318: 467-472.
-
(1988)
N Engl J Med
, vol.318
, pp. 467-472
-
-
Ravussin, E.1
Lillioja, S.2
Knowler, W.C.3
Christin, L.4
Freymond, D.5
Abbott, W.G.6
Boyce, V.7
Howard, B.V.8
Bogardus, C.9
-
34
-
-
0027049534
-
Molecular characterization of the mouse agouti locus
-
Bultman SJ, Michaud EJ, Woychik RP. Molecular characterization of the mouse agouti locus. Cell 1992; 71: 1195-1204.
-
(1992)
Cell
, vol.71
, pp. 1195-1204
-
-
Bultman, S.J.1
Michaud, E.J.2
Woychik, R.P.3
-
35
-
-
0037129380
-
Nonalcoholic fatty liver disease
-
Angulo P. Nonalcoholic fatty liver disease. N Engl J Med 2002; 346: 1221-1231.
-
(2002)
N Engl J Med
, vol.346
, pp. 1221-1231
-
-
Angulo, P.1
-
36
-
-
0033982172
-
Prevalence of and risk factors for hepatic steatosis in Northern Italy
-
Bellentani S, Saccoccio G, Masutti F, Croce LS, Brandi G, Sasso F, Cristanini G, Tiribelli C. Prevalence of and risk factors for hepatic steatosis in Northern Italy. Ann Intern Med 2000; 132: 112-117.
-
(2000)
Ann Intern Med
, vol.132
, pp. 112-117
-
-
Bellentani, S.1
Saccoccio, G.2
Masutti, F.3
Croce, L.S.4
Brandi, G.5
Sasso, F.6
Cristanini, G.7
Tiribelli, C.8
-
37
-
-
0035431018
-
Nonalcoholic fatty liver disease: A feature of the metabolic syndrome
-
Marchesini G, Brizi M, Bianchi G, Tomassetti S, Bugianesi E, Lenzi M, McCullough AJ, Natale S, Forlani G, Melchionda N. Nonalcoholic fatty liver disease: a feature of the metabolic syndrome. Diabetes 2001; 50: 1844-1850.
-
(2001)
Diabetes
, vol.50
, pp. 1844-1850
-
-
Marchesini, G.1
Brizi, M.2
Bianchi, G.3
Tomassetti, S.4
Bugianesi, E.5
Lenzi, M.6
McCullough, A.J.7
Natale, S.8
Forlani, G.9
Melchionda, N.10
-
38
-
-
0036217052
-
Disordered fat storage and mobilization in the pathogenesis of insulin resistance and type 2 diabetes
-
Lewis GF, Carpentier A, Adeli K, Giacca A. Disordered fat storage and mobilization in the pathogenesis of insulin resistance and type 2 diabetes. Endocr Rev 2002; 23: 201-229.
-
(2002)
Endocr Rev
, vol.23
, pp. 201-229
-
-
Lewis, G.F.1
Carpentier, A.2
Adeli, K.3
Giacca, A.4
-
39
-
-
0021436667
-
Turnover and splanchnic metabolism of free fatty acids and ketones in insulin-dependent diabetics at rest and in response to exercise
-
Wahren J, Sato Y, Ostman J, Hagenfeldt L, Felig P. Turnover and splanchnic metabolism of free fatty acids and ketones in insulin-dependent diabetics at rest and in response to exercise. J Clin Invest 1984; 73: 1367-1376.
-
(1984)
J Clin Invest
, vol.73
, pp. 1367-1376
-
-
Wahren, J.1
Sato, Y.2
Ostman, J.3
Hagenfeldt, L.4
Felig, P.5
-
40
-
-
2642583241
-
The ins and outs of mitochondrial dysfunction in NASH
-
Fromenty B, Robin MA, Igoudjil A, Mansouri A, Pessayre D. The ins and outs of mitochondrial dysfunction in NASH. Diabetes Metab 2004; 30: 121-138.
-
(2004)
Diabetes Metab
, vol.30
, pp. 121-138
-
-
Fromenty, B.1
Robin, M.A.2
Igoudjil, A.3
Mansouri, A.4
Pessayre, D.5
-
41
-
-
0842269198
-
Hepatic steatosis in obese patients: Clinical aspects and prognostic significance
-
Festi D, Colecchia A, Sacco T, Bondi M, Roda E, Marchesini G. Hepatic steatosis in obese patients: clinical aspects and prognostic significance. Obes Rev 2004; 5: 27-42.
-
(2004)
Obes Rev
, vol.5
, pp. 27-42
-
-
Festi, D.1
Colecchia, A.2
Sacco, T.3
Bondi, M.4
Roda, E.5
Marchesini, G.6
-
42
-
-
0034730532
-
The biosynthesis of hepatic cholesterol esters and triglycerides is impaired in mice with a disruption of the gene for stearoyl-CoA desaturase 1
-
Miyazaki M, Kim YC, Gray-Keller MP, Attie AD, Ntambi JM. The biosynthesis of hepatic cholesterol esters and triglycerides is impaired in mice with a disruption of the gene for stearoyl-CoA desaturase 1. J Biol Chem 2000; 275: 30132-30138.
-
(2000)
J Biol Chem
, vol.275
, pp. 30132-30138
-
-
Miyazaki, M.1
Kim, Y.C.2
Gray-Keller, M.P.3
Attie, A.D.4
Ntambi, J.M.5
-
43
-
-
0034958783
-
A lipogenic diet in mice with a disruption of the stearoyl-CoA desaturase 1 gene reveals a stringent requirement of endogenous monounsaturated fatty acids for triglyceride synthesis
-
Miyazaki M, Kim YC, Ntambi JM. A lipogenic diet in mice with a disruption of the stearoyl-CoA desaturase 1 gene reveals a stringent requirement of endogenous monounsaturated fatty acids for triglyceride synthesis. J Lipid Res 2001; 42: 1018-1024.
-
(2001)
J Lipid Res
, vol.42
, pp. 1018-1024
-
-
Miyazaki, M.1
Kim, Y.C.2
Ntambi, J.M.3
-
44
-
-
4544231849
-
Reduced adiposity and liver steatosis by stearoyl-CoA desaturase deficiency are independent of peroxisome proliferator-activated peceptor-{alpha}
-
Miyazaki M, Dobrzyn A, Sampath H, Lee SH, Man WC, Chu K, Peters JM, Gonzalez FJ, Ntambi JM. Reduced adiposity and liver steatosis by stearoyl-CoA desaturase deficiency are independent of peroxisome proliferator-activated peceptor-{alpha}. J Biol Chem 2004; 279: 35017-35024.
-
(2004)
J Biol Chem
, vol.279
, pp. 35017-35024
-
-
Miyazaki, M.1
Dobrzyn, A.2
Sampath, H.3
Lee, S.H.4
Man, W.C.5
Chu, K.6
Peters, J.M.7
Gonzalez, F.J.8
Ntambi, J.M.9
-
45
-
-
2942706241
-
Increase in long-chain polyunsaturated fatty acid n - 6/n - 3 ratio in relation to hepatic steatosis in patients with non-alcoholic fatty liver disease
-
Araya J, Rodrigo R, Videla LA, Thielemann L, Orellana M, Pettinelli P, Poniachik J. Increase in long-chain polyunsaturated fatty acid n - 6/n - 3 ratio in relation to hepatic steatosis in patients with non-alcoholic fatty liver disease. Clin Sci (Lond) 2004; 106: 635-643.
-
(2004)
Clin Sci (Lond)
, vol.106
, pp. 635-643
-
-
Araya, J.1
Rodrigo, R.2
Videla, L.A.3
Thielemann, L.4
Orellana, M.5
Pettinelli, P.6
Poniachik, J.7
-
46
-
-
0032567445
-
Nuclear sterol regulatory element-binding proteins activate genes responsible for the entire program of unsaturated fatty acid biosynthesis in transgenic mouse liver
-
Shimomura I, Shimano H, Korn BS, Bashmakov Y, Horton JD. Nuclear sterol regulatory element-binding proteins activate genes responsible for the entire program of unsaturated fatty acid biosynthesis in transgenic mouse liver. J Biol Chem 1998; 273: 35299-35306.
-
(1998)
J Biol Chem
, vol.273
, pp. 35299-35306
-
-
Shimomura, I.1
Shimano, H.2
Korn, B.S.3
Bashmakov, Y.4
Horton, J.D.5
-
47
-
-
0036864358
-
Regulation of fatty acid synthesis and oxidation by the AMP-activated protein kinase
-
Hardie DG. Pan DA. Regulation of fatty acid synthesis and oxidation by the AMP-activated protein kinase. Biochem Soc Trans 2002; 30: 1064-1070.
-
(2002)
Biochem Soc Trans
, vol.30
, pp. 1064-1070
-
-
Hardie, D.G.1
Pan, D.A.2
-
48
-
-
0017738601
-
A possible role for malonyl-CoA in the regulation of hepatic fatty acid oxidation and ketogenesis
-
McGarry JD, Mannaerts GP, Foster DW. A possible role for malonyl-CoA in the regulation of hepatic fatty acid oxidation and ketogenesis. J Clin Invest 1977; 60: 265-270.
-
(1977)
J Clin Invest
, vol.60
, pp. 265-270
-
-
McGarry, J.D.1
Mannaerts, G.P.2
Foster, D.W.3
-
49
-
-
0031965513
-
Sterol regulatory element binding proteins (SREBPs): Controllers of lipid synthesis and cellular uptake
-
Brown MS, Goldstein JL. Sterol regulatory element binding proteins (SREBPs): controllers of lipid synthesis and cellular uptake. Nutr Rev 1998; 56: S1-S3.
-
(1998)
Nutr Rev
, vol.56
-
-
Brown, M.S.1
Goldstein, J.L.2
-
50
-
-
0037453718
-
Peroxisome-proliferator-activated receptor delta activates fat metabolism to prevent obesity
-
Wang YX, Lee CH, Tiep S, Yu RT, Ham J, Kang H, Evans RM. Peroxisome-proliferator-activated receptor delta activates fat metabolism to prevent obesity. Cell 2003; 113: 159-170.
-
(2003)
Cell
, vol.113
, pp. 159-170
-
-
Wang, Y.X.1
Lee, C.H.2
Tiep, S.3
Yu, R.T.4
Ham, J.5
Kang, H.6
Evans, R.M.7
-
51
-
-
9144271149
-
Activation of peroxisome proliferator-activated receptor delta induces fatty acid beta-oxidation in skeletal muscle and attenuates metabolic syndrome
-
Tanaka T, Yamamoto J, Iwasaki S, Asaba H, Hamura H, Ikeda Y, Watanabe M, Magoori K, Ioka RX, Tachibana K, Watanabe Y, Uchiyama Y, Sumi K, Iguchi H, Ito S, Doi T, Hamakubo T, Naito M, Auwerx J, Yanagisawa M, Kodama T, Sakai J. Activation of peroxisome proliferator-activated receptor delta induces fatty acid beta-oxidation in skeletal muscle and attenuates metabolic syndrome. Proc Natl Acad Sci USA 2003; 100: 15924-15929.
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 15924-15929
-
-
Tanaka, T.1
Yamamoto, J.2
Iwasaki, S.3
Asaba, H.4
Hamura, H.5
Ikeda, Y.6
Watanabe, M.7
Magoori, K.8
Ioka, R.X.9
Tachibana, K.10
Watanabe, Y.11
Uchiyama, Y.12
Sumi, K.13
Iguchi, H.14
Ito, S.15
Doi, T.16
Hamakubo, T.17
Naito, M.18
Auwerx, J.19
Yanagisawa, M.20
Kodama, T.21
Sakai, J.22
more..
-
52
-
-
0036846245
-
Relationship between stearoyl-CoA desaturase activity and plasma triglycerides in human and mouse hypertriglyceridemia
-
Attie AD, Krauss RM, Gray-Keller MP, Brownlie A, Miyazaki M, Kastelein JJ, Lusis AJ, Stalenhoef AF, Stoehr JP, Hayden MR, Ntambi JM. Relationship between stearoyl-CoA desaturase activity and plasma triglycerides in human and mouse hypertriglyceridemia. J Lipid Res 2002; 43: 1899-1907.
-
(2002)
J Lipid Res
, vol.43
, pp. 1899-1907
-
-
Attie, A.D.1
Krauss, R.M.2
Gray-Keller, M.P.3
Brownlie, A.4
Miyazaki, M.5
Kastelein, J.J.6
Lusis, A.J.7
Stalenhoef, A.F.8
Stoehr, J.P.9
Hayden, M.R.10
Ntambi, J.M.11
-
55
-
-
0037458568
-
Stearoyl-CoA desaturase inhibits ATP-binding cassette transporter A1-mediated cholesterol efflux and modulates membrane domain structure
-
Sun Y, Hao M, Luo Y, Liang CP, Silver DL, Cheng C, Maxfield FR, Tall AR. Stearoyl-CoA desaturase inhibits ATP-binding cassette transporter A1-mediated cholesterol efflux and modulates membrane domain structure. J Biol Chem 2003; 278: 5813-5820.
-
(2003)
J Biol Chem
, vol.278
, pp. 5813-5820
-
-
Sun, Y.1
Hao, M.2
Luo, Y.3
Liang, C.P.4
Silver, D.L.5
Cheng, C.6
Maxfield, F.R.7
Tall, A.R.8
-
56
-
-
0033927667
-
Cellular mechanisms of insulin resistance
-
Shulman GI. Cellular mechanisms of insulin resistance. J Clin Invest 2000; 106: 171-176.
-
(2000)
J Clin Invest
, vol.106
, pp. 171-176
-
-
Shulman, G.I.1
-
57
-
-
0035130102
-
Diseases of liporegulation: New perspective on obesity and related disorders
-
Unger RH, Orci L. Diseases of liporegulation: new perspective on obesity and related disorders. FASEB J 2001; 15: 312-321.
-
(2001)
FASEB J
, vol.15
, pp. 312-321
-
-
Unger, R.H.1
Orci, L.2
-
58
-
-
0037197693
-
Molecular differences caused by differentiation of 3T3-L1 preadipocytes in the presence of either dehydroepiandrosterone (DHEA) or 7-oxo-DHEA
-
Gomez FE, Miyazaki M, Kim YC, Marwah P, Lardy HA, Ntambi JM, Fox BG. Molecular differences caused by differentiation of 3T3-L1 preadipocytes in the presence of either dehydroepiandrosterone (DHEA) or 7-oxo-DHEA. Biochemistry 2002; 41: 5473-5482.
-
(2002)
Biochemistry
, vol.41
, pp. 5473-5482
-
-
Gomez, F.E.1
Miyazaki, M.2
Kim, Y.C.3
Marwah, P.4
Lardy, H.A.5
Ntambi, J.M.6
Fox, B.G.7
-
60
-
-
3142583174
-
Oleoylethanolamide stimulates lipolysis by activating the nuclear receptor peroxisome proliferator-activated receptor alpha (PPAR-alpha)
-
Guzman M, Lo Verme J, Fu J, Oveisi F, Blazquez C, Piomelli D. Oleoylethanolamide stimulates lipolysis by activating the nuclear receptor peroxisome proliferator-activated receptor alpha (PPAR-alpha). J Biol Chem 2004; 279: 27849-27854.
-
(2004)
J Biol Chem
, vol.279
, pp. 27849-27854
-
-
Guzman, M.1
Lo Verme, J.2
Fu, J.3
Oveisi, F.4
Blazquez, C.5
Piomelli, D.6
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