Combined therapy of dietary fish oil and stearoyl-CoA desaturase 1 inhibition prevents the metabolic syndrome and atherosclerosis

Arteriosclerosis, Thrombosis, and Vascular Biology

Volumn 30, Issue 1, 2010, Pages 24-30

  Brown, J Mark ^a   Chung, Soonkyu ^a   Sawyer, Janet K ^a   Degirolamo, Chiara ^a   Alger, Heather M ^b   Nguyen, Tam M ^a   Zhu, Xuewei ^a   Duong, My Ngan ^c   Brown, Amanda L ^a   Lord, Caleb ^a   Shah, Ramesh ^a   Davis, Matthew A ^a   Kelley, Kathryn ^a   Wilson, Martha D ^a   Madenspacher, Jennifer ^d   Fessler, Michael B ^d   Parks, John S ^a   Rudel, Lawrence L ^a  

^a WAKE FOREST SCHOOL OF MEDICINE   (United States)

^b Department of Biochemistry ^*

^c LERNER RESEARCH INSTITUTE   (United States)

^d NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

Author keywords

Atherosclerosis; Fish oil; Inflammation; Metabolic syndrome; Saturated fat

Indexed keywords

ACYL COENZYME A DESATURASE; ANTISENSE OLIGONUCLEOTIDE; FISH OIL; SATURATED FATTY ACID;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ATHEROGENESIS; ATHEROSCLEROSIS; CONTROLLED STUDY; ENZYME INHIBITION; FAT INTAKE; INFLAMMATION; MACROPHAGE; MALE; METABOLIC SYNDROME X; MOUSE; NONHUMAN; PRIORITY JOURNAL;

ANIMALS; APOLIPOPROTEIN B-100; ATHEROSCLEROSIS; COMBINED MODALITY THERAPY; DIETARY FATS, UNSATURATED; FATTY ACIDS; FATTY LIVER; FISH OILS; HYPERLIPIDEMIAS; INSULIN RESISTANCE; MACROPHAGES; MALE; METABOLIC SYNDROME X; MICE; MICE, MUTANT STRAINS; OBESITY; OLIGORIBONUCLEOTIDES, ANTISENSE; RECEPTORS, LDL; STEAROYL-COA DESATURASE; TOLL-LIKE RECEPTOR 4;

EID: 73849124961     PISSN: 10795642     EISSN: None     Source Type: Journal    
DOI: 10.1161/ATVBAHA.109.198036     Document Type: Article

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