A simple method for analyzing actives in random RNAi screens: Introducing the "H score" for hit nomination & gene prioritization

Combinatorial Chemistry and High Throughput Screening

Volumn 15, Issue 9, 2012, Pages 686-704

  Bhinder, Bhavneet ^a   Djaballah, Hakim ^a  

^a MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

Author keywords

3'UTR; BDA method; EsiRNA; H score; HCS; Heptamer; HTS; MiRNA; Off target effect; Randomness; RNAi; Screening; Seed sequence; ShRNA; SiRNA

Indexed keywords

HETERODUPLEX; MICRORNA; SHORT HAIRPIN RNA; SMALL INTERFERING RNA;

3' UNTRANSLATED REGION; ARTICLE; CLASSIFICATION; DATA ANALYSIS; GENE; GENE IDENTIFICATION; GENE LIBRARY; HUMAN; METHODOLOGY; PEER GROUP; PRIORITY JOURNAL; PROCESS DEVELOPMENT; PUBLICATION; RNA ANALYSIS; RNA INTERFERENCE; RNA SEQUENCE;

BASE SEQUENCE; DATABASES, GENETIC; GENETIC TECHNIQUES; HUMANS; MOLECULAR SEQUENCE DATA; RNA INTERFERENCE; SEQUENCE ANALYSIS, RNA;

EID: 84870465072     PISSN: 13862073     EISSN: 18755402     Source Type: Journal    
DOI: 10.2174/138620712803519671     Document Type: Article

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