Attenuation of acute nitrogen mustard-induced lung injury, inflammation and fibrogenesis by a nitric oxide synthase inhibitor

Toxicology and Applied Pharmacology

Volumn 265, Issue 3, 2012, Pages 279-291

  Malaviya, Rama ^a   Venosa, Alessandro ^a   Hall, LeRoy ^b   Gow, Andrew J ^a   Sinko, Patrick J ^a   Laskin, Jeffrey D ^c   Laskin, Debra L ^a  

^a RUTGERS UNIVERSITY   (United States)

^b Johnson and Johnson   (United States)

^c RUTGERS ROBERT WOOD JOHNSON MEDICAL SCHOOL   (United States)

Author keywords

INOS; Macrophages; Nitric oxide; Oxidative stress; Pulmonary toxicity; Vesicants

Indexed keywords

AMINOGUANIDINE; CHLORMETHINE; CYCLINE; CYCLOOXYGENASE 2; FIBRIN; HEME OXYGENASE 1; INDUCIBLE NITRIC OXIDE SYNTHASE; MANGANESE SUPEROXIDE DISMUTASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; FIBROGENESIS; HISTOPATHOLOGY; LUNG FIBROSIS; LUNG INJURY; LUNG LAVAGE; LUNG TOXICITY; MACROPHAGE; MALE; NONHUMAN; OXIDATIVE STRESS; RAT;

ANIMALS; BRONCHOALVEOLAR LAVAGE FLUID; DRUG INTERACTIONS; ENZYME INHIBITORS; FIBROSIS; GUANIDINES; HEME OXYGENASE-1; IMMUNOHISTOCHEMISTRY; LUNG INJURY; MALE; MECHLORETHAMINE; NITRIC OXIDE SYNTHASE TYPE II; PROLIFERATING CELL NUCLEAR ANTIGEN; RATS; RATS, WISTAR; SUPEROXIDE DISMUTASE;

RATTUS;

EID: 84870296962     PISSN: 0041008X     EISSN: 10960333     Source Type: Journal    
DOI: 10.1016/j.taap.2012.08.027     Document Type: Article

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