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Volumn 50, Issue 1, 2009, Pages 68-77

Early and late changes of MMP-2 and MMP-9 in bleomycin-induced pulmonary fibrosis

Author keywords

Bleomycin; Matrix metalloproteinase; Matrix metalloproteinase 9; Matrix metalloproteinase 2; Pulmonary fibrosis

Indexed keywords

BLEOMYCIN; GELATINASE A; GELATINASE B;

EID: 62749130628     PISSN: 05135796     EISSN: None     Source Type: Journal    
DOI: 10.3349/ymj.2009.50.1.68     Document Type: Article
Times cited : (72)

References (46)
  • 1
    • 0025089518 scopus 로고
    • Pathobiology of pulmonary fibrosis
    • Crouch E. Pathobiology of pulmonary fibrosis. Am J Physiol 1990;259(4 Pt 1):L159-84.
    • (1990) Am J Physiol , vol.259 , Issue.4 PART 1
    • Crouch, E.1
  • 2
    • 0026903364 scopus 로고
    • The matrix metalloproteinases and their inhibitors
    • Murphy G, Docherty AJ. The matrix metalloproteinases and their inhibitors. Am J Respir Cell Mol Biol 1992;7: 120-5.
    • (1992) Am J Respir Cell Mol Biol , vol.7 , pp. 120-125
    • Murphy, G.1    Docherty, A.J.2
  • 3
    • 0029840755 scopus 로고    scopus 로고
    • Immunohistochemical study of metalloproteinases and their tissue inhibitors in the lungs of patients with diffuse alveolar damage and idiopathic pulmonary fibrosis
    • Hayashi T, Stetler-Stevenson WG, Fleming MV, Fishback N, Koss MN, Liotta LA, et al. Immunohistochemical study of metalloproteinases and their tissue inhibitors in the lungs of patients with diffuse alveolar damage and idiopathic pulmonary fibrosis. Am J Pathol 1996; 149:1241-56.
    • (1996) Am J Pathol , vol.149 , pp. 1241-1256
    • Hayashi, T.1    Stetler-Stevenson, W.G.2    Fleming, M.V.3    Fishback, N.4    Koss, M.N.5    Liotta, L.A.6
  • 4
    • 0031780581 scopus 로고    scopus 로고
    • Localization of matrix metalloproteinases-1, -2, and -9 and tissue inhibitor of metalloproteinase-2 in interstitial lung diseases
    • Fukuda Y, Ishizaki M, Kudoh S, Kitaichi M, Yamanaka N. Localization of matrix metalloproteinases-1, -2, and -9 and tissue inhibitor of metalloproteinase-2 in interstitial lung diseases. Lab Invest 1998;78:687-98.
    • (1998) Lab Invest , vol.78 , pp. 687-698
    • Fukuda, Y.1    Ishizaki, M.2    Kudoh, S.3    Kitaichi, M.4    Yamanaka, N.5
  • 5
    • 0033679330 scopus 로고    scopus 로고
    • Characteristic elevation of matrix metalloproteinase activity in idiopathic interstitial pneumonias
    • Suga M, Iyonaga K, Okamoto T, Gushima Y, Miyakawa H, Akaike T, et al. Characteristic elevation of matrix metalloproteinase activity in idiopathic interstitial pneumonias. Am J Respir Crit Care Med 2000;162:1949-56.
    • (2000) Am J Respir Crit Care Med , vol.162 , pp. 1949-1956
    • Suga, M.1    Iyonaga, K.2    Okamoto, T.3    Gushima, Y.4    Miyakawa, H.5    Akaike, T.6
  • 6
    • 0031710577 scopus 로고    scopus 로고
    • Matrix metalloproteinase-mediated extracellular matrix protein degradation in human pulmonary emphysema
    • Ohnishi K, Takagi M, Kurokawa Y, Satomi S, Konttinen YT. Matrix metalloproteinase-mediated extracellular matrix protein degradation in human pulmonary emphysema. Lab Invest 1998;78:1077-87.
    • (1998) Lab Invest , vol.78 , pp. 1077-1087
    • Ohnishi, K.1    Takagi, M.2    Kurokawa, Y.3    Satomi, S.4    Konttinen, Y.T.5
  • 7
    • 0034101866 scopus 로고    scopus 로고
    • Upregulation of gelatinases A and B, collagenases 1 and 2, and increased parenchymal cell death in COPD
    • Segura-Valdez L, Pardo A, Gaxiola M, Uhal BD, Becerril C, Selman M. Upregulation of gelatinases A and B, collagenases 1 and 2, and increased parenchymal cell death in COPD. Chest 2000;117:684-94.
    • (2000) Chest , vol.117 , pp. 684-694
    • Segura-Valdez, L.1    Pardo, A.2    Gaxiola, M.3    Uhal, B.D.4    Becerril, C.5    Selman, M.6
  • 8
    • 0031041367 scopus 로고    scopus 로고
    • Activation of MMP-9 by neutrophil elastase in an in vivo model of acute lung injury
    • Ferry G, Lonchampt M, Pennel L, de Nanteuil G, Canet E, Tucker GC. Activation of MMP-9 by neutrophil elastase in an in vivo model of acute lung injury. FEBS Lett 1997;402:111-5.
    • (1997) FEBS Lett , vol.402 , pp. 111-115
    • Ferry, G.1    Lonchampt, M.2    Pennel, L.3    de Nanteuil, G.4    Canet, E.5    Tucker, G.C.6
  • 9
    • 0033126693 scopus 로고    scopus 로고
    • Overexpression of alveolar macrophage gelatinase B (MMP-9) in patients with idiopathic pulmonary fibrosis: Effects of steroid and immunosuppressive treatment
    • Lemjabbar H, Gosset P, Lechapt-Zalcman E, Franco-Montoya ML, Wallaert B, Harf A, et al. Overexpression of alveolar macrophage gelatinase B (MMP-9) in patients with idiopathic pulmonary fibrosis: effects of steroid and immunosuppressive treatment. Am J Respir Cell Mol Biol 1999;20:903-13.
    • (1999) Am J Respir Cell Mol Biol , vol.20 , pp. 903-913
    • Lemjabbar, H.1    Gosset, P.2    Lechapt-Zalcman, E.3    Franco-Montoya, M.L.4    Wallaert, B.5    Harf, A.6
  • 10
    • 0032967436 scopus 로고    scopus 로고
    • Extracellular matrix deposition by primary human lung fibroblasts in response to TGF-beta1 and TGF-beta3
    • Eickelberg O, Köhler E, Reichenberger F, Bertschin S, Woodtli T, Erne P, et al. Extracellular matrix deposition by primary human lung fibroblasts in response to TGF-beta1 and TGF-beta3. Am J Physiol 1999;276(5 Pt 1): L814-24.
    • (1999) Am J Physiol , vol.276 , Issue.5 PART 1
    • Eickelberg, O.1    Köhler, E.2    Reichenberger, F.3    Bertschin, S.4    Woodtli, T.5    Erne, P.6
  • 11
  • 12
    • 0037086296 scopus 로고    scopus 로고
    • Bleomycin-induced lung fibrosis: The authors should have used another method to induce pulmonary lesions resembling human idiopathic pulmonary fibrosis
    • author reply 6
    • Gabazza EC, Taguchi O, Adachi Y. Bleomycin-induced lung fibrosis: the authors should have used another method to induce pulmonary lesions resembling human idiopathic pulmonary fibrosis. Am J Respir Crit Care Med 2002;165:845-6; author reply 6.
    • (2002) Am J Respir Crit Care Med , vol.165 , pp. 845-846
    • Gabazza, E.C.1    Taguchi, O.2    Adachi, Y.3
  • 13
    • 0027394794 scopus 로고
    • Association of p53 protein expression with tumor cell proliferation rate and clinical outcome in node-negative breast cancer
    • Allred DC, Clark GM, Elledge R, Fuqua SA, Brown RW, Chamness GC, et al. Association of p53 protein expression with tumor cell proliferation rate and clinical outcome in node-negative breast cancer. J Natl Cancer Inst 1993;85:200-6.
    • (1993) J Natl Cancer Inst , vol.85 , pp. 200-206
    • Allred, D.C.1    Clark, G.M.2    Elledge, R.3    Fuqua, S.A.4    Brown, R.W.5    Chamness, G.C.6
  • 14
    • 0014949207 scopus 로고
    • Cleavage of structural proteins during the assembly of the head of bacteriophage T4
    • Laemmli UK. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 1970;227:680-5.
    • (1970) Nature , vol.227 , pp. 680-685
    • Laemmli, U.K.1
  • 15
    • 0015290155 scopus 로고
    • Morphogenesis of alveolar bronchiolization
    • Nettesheim P, Szakal AK. Morphogenesis of alveolar bronchiolization. Lab Invest 1972;26:210-9.
    • (1972) Lab Invest , vol.26 , pp. 210-219
    • Nettesheim, P.1    Szakal, A.K.2
  • 16
    • 0036570355 scopus 로고    scopus 로고
    • Con: Inflammatory mechanisms are not a minor component of the pathogenesis of idiopathic pulmonary fibrosis
    • discussion 1207-8
    • Strieter RM. Con: Inflammatory mechanisms are not a minor component of the pathogenesis of idiopathic pulmonary fibrosis. Am J Respir Crit Care Med 2002; 165:1206-7; discussion 1207-8.
    • (2002) Am J Respir Crit Care Med , vol.165 , pp. 1206-1207
    • Strieter, R.M.1
  • 17
    • 0035895243 scopus 로고    scopus 로고
    • Idiopathic pulmonary fibrosis: Prevailing and evolving hypotheses about its pathogenesis and implications for therapy
    • Selman M, King TE, Pardo A. Idiopathic pulmonary fibrosis: prevailing and evolving hypotheses about its pathogenesis and implications for therapy. Ann Intern Med 2001;134:136-51.
    • (2001) Ann Intern Med , vol.134 , pp. 136-151
    • Selman, M.1    King, T.E.2    Pardo, A.3
  • 18
    • 25444432522 scopus 로고    scopus 로고
    • A new direction in the pathogenesis of idiopathic pulmonary fibrosis?
    • Gauldie J, Kolb M, Sime PJ. A new direction in the pathogenesis of idiopathic pulmonary fibrosis? Respir Res 2002;3:1.
    • (2002) Respir Res , vol.3 , pp. 1
    • Gauldie, J.1    Kolb, M.2    Sime, P.J.3
  • 19
    • 0242475243 scopus 로고    scopus 로고
    • Pathogenetic mechanisms in usual interstitial pneumonia/idiopathic pulmonary fibrosis
    • White ES, Lazar MH, Thannickal VJ. Pathogenetic mechanisms in usual interstitial pneumonia/idiopathic pulmonary fibrosis. J Pathol 2003;201:343-54.
    • (2003) J Pathol , vol.201 , pp. 343-354
    • White, E.S.1    Lazar, M.H.2    Thannickal, V.J.3
  • 21
    • 0037241857 scopus 로고    scopus 로고
    • Re-evaluation of fibrogenic cytokines in lung fibrosis
    • Kelly M, Kolb M, Bonniaud P, Gauldie J. Re-evaluation of fibrogenic cytokines in lung fibrosis. Curr Pharm Des 2003;9:39-49.
    • (2003) Curr Pharm Des , vol.9 , pp. 39-49
    • Kelly, M.1    Kolb, M.2    Bonniaud, P.3    Gauldie, J.4
  • 22
    • 0034221875 scopus 로고    scopus 로고
    • Role of gelatinases MMP-2 and MMP-9 in tissue remodeling following acute lung injury
    • Corbel M, Boichot E, Lagente V. Role of gelatinases MMP-2 and MMP-9 in tissue remodeling following acute lung injury. Braz J Med Biol Res 2000;33:749-54.
    • (2000) Braz J Med Biol Res , vol.33 , pp. 749-754
    • Corbel, M.1    Boichot, E.2    Lagente, V.3
  • 23
    • 0031659907 scopus 로고    scopus 로고
    • Gelatinases A and B are up-regulated in rat lungs by subacute hyperoxia: Pathogenetic implications
    • Pardo A, Barrios R, Maldonado V, Meléndez J, Pérez J, Ruiz V, et al. Gelatinases A and B are up-regulated in rat lungs by subacute hyperoxia: pathogenetic implications. Am J Pathol 1998;153:833-44.
    • (1998) Am J Pathol , vol.153 , pp. 833-844
    • Pardo, A.1    Barrios, R.2    Maldonado, V.3    Meléndez, J.4    Pérez, J.5    Ruiz, V.6
  • 24
    • 33847778535 scopus 로고    scopus 로고
    • Time course of matrix metalloproteases and tissue inhibitors in bleomycin-induced pulmonary fibrosis
    • Oggionni T, Morbini P, Inghilleri S, Palladini G, Tozzi R, Vitulo P, et al. Time course of matrix metalloproteases and tissue inhibitors in bleomycin-induced pulmonary fibrosis. Eur J Histochem 2006;50:317-25.
    • (2006) Eur J Histochem , vol.50 , pp. 317-325
    • Oggionni, T.1    Morbini, P.2    Inghilleri, S.3    Palladini, G.4    Tozzi, R.5    Vitulo, P.6
  • 25
    • 0032437893 scopus 로고    scopus 로고
    • Immunohistochemical and gelatin zymography studies for matrix metalloproteinases in bleomycin-induced pulmonary fibrosis
    • Yaguchi T, Fukuda Y, Ishizaki M, Yamanaka N. Immunohistochemical and gelatin zymography studies for matrix metalloproteinases in bleomycin-induced pulmonary fibrosis. Pathol Int 1998;48:954-63.
    • (1998) Pathol Int , vol.48 , pp. 954-963
    • Yaguchi, T.1    Fukuda, Y.2    Ishizaki, M.3    Yamanaka, N.4
  • 26
    • 0025158119 scopus 로고
    • Cell proliferation during the process of bleomycin-induced pulmonary fibrosis in rats
    • Kawamoto M, Fukuda Y. Cell proliferation during the process of bleomycin-induced pulmonary fibrosis in rats. Acta Pathol Jpn 1990;40:227-38.
    • (1990) Acta Pathol Jpn , vol.40 , pp. 227-238
    • Kawamoto, M.1    Fukuda, Y.2
  • 27
    • 0024822235 scopus 로고
    • An immunohistochemical study of architectural remodeling and connective tissue synthesis in pulmonary fibrosis
    • Kuhn C 3rd, Boldt J, King TE Jr, Crouch E, Vartio T, McDonald JA. An immunohistochemical study of architectural remodeling and connective tissue synthesis in pulmonary fibrosis. Am Rev Respir Dis 1989; 140:1693-703.
    • (1989) Am Rev Respir Dis , vol.140 , pp. 1693-1703
    • Kuhn 3rd, C.1    Boldt, J.2    King Jr, T.E.3    Crouch, E.4    Vartio, T.5    McDonald, J.A.6
  • 28
    • 0033873628 scopus 로고    scopus 로고
    • Gelatinase B is required for alveolar bronchiolization after intratracheal bleomycin
    • Betsuyaku T, Fukuda Y, Parks WC, Shipley JM, Senior RM. Gelatinase B is required for alveolar bronchiolization after intratracheal bleomycin. Am J Pathol 2000; 157:525-35.
    • (2000) Am J Pathol , vol.157 , pp. 525-535
    • Betsuyaku, T.1    Fukuda, Y.2    Parks, W.C.3    Shipley, J.M.4    Senior, R.M.5
  • 29
    • 0033606774 scopus 로고    scopus 로고
    • Airway epithelial cell migration dynamics. MMP-9 role in cell-extracellular matrix remodeling
    • Legrand C, Gilles C, Zahm JM, Polette M, Buisson AC, Kaplan H, et al. Airway epithelial cell migration dynamics. MMP-9 role in cell-extracellular matrix remodeling. J Cell Biol 1999;146:517-29.
    • (1999) J Cell Biol , vol.146 , pp. 517-529
    • Legrand, C.1    Gilles, C.2    Zahm, J.M.3    Polette, M.4    Buisson, A.C.5    Kaplan, H.6
  • 30
    • 0034813014 scopus 로고    scopus 로고
    • Role of MMP-2 in alveolar epithelial cell repair after bleomycin administration in rabbits
    • Kunugi S, Fukuda Y, Ishizaki M, Yamanaka N. Role of MMP-2 in alveolar epithelial cell repair after bleomycin administration in rabbits. Lab Invest 2001;81:1309-18.
    • (2001) Lab Invest , vol.81 , pp. 1309-1318
    • Kunugi, S.1    Fukuda, Y.2    Ishizaki, M.3    Yamanaka, N.4
  • 31
    • 0031685075 scopus 로고    scopus 로고
    • TNF and IL-6 mediate MIP-1alpha expression in bleomycin-induced lung injury
    • Smith RE, Strieter RM, Phan SH, Lukacs N, Kunkel SL. TNF and IL-6 mediate MIP-1alpha expression in bleomycin-induced lung injury. J Leukoc Biol 1998;64:528-36.
    • (1998) J Leukoc Biol , vol.64 , pp. 528-536
    • Smith, R.E.1    Strieter, R.M.2    Phan, S.H.3    Lukacs, N.4    Kunkel, S.L.5
  • 33
    • 0037637437 scopus 로고    scopus 로고
    • Sputum matrix metalloproteinase-9, tissue inhibitor of metalloprotinease-1, and their molar ratio in patients with chronic obstructive pulmonary disease, idiopathic pulmonary fibrosis and healthy subjects
    • Beeh KM, Beier J, Kornmann O, Buhl R. Sputum matrix metalloproteinase-9, tissue inhibitor of metalloprotinease-1, and their molar ratio in patients with chronic obstructive pulmonary disease, idiopathic pulmonary fibrosis and healthy subjects. Respir Med 2003;97:634-9.
    • (2003) Respir Med , vol.97 , pp. 634-639
    • Beeh, K.M.1    Beier, J.2    Kornmann, O.3    Buhl, R.4
  • 34
    • 28444463303 scopus 로고    scopus 로고
    • Inflammatory mediators in chronic obstructive pulmonary disease
    • Chung KF. Inflammatory mediators in chronic obstructive pulmonary disease. Curr Drug Targets Inflamm Allergy 2005;4:619-25.
    • (2005) Curr Drug Targets Inflamm Allergy , vol.4 , pp. 619-625
    • Chung, K.F.1
  • 35
    • 0036138869 scopus 로고    scopus 로고
    • Increased production of matrix metalloproteinase-2 in alveolar macrophages and regulation by interleukin-10 in patients with acute pulmonary sarcoidosis
    • John M, Oltmanns U, Fietze I, Witt C, Jung K. Increased production of matrix metalloproteinase-2 in alveolar macrophages and regulation by interleukin-10 in patients with acute pulmonary sarcoidosis. Exp Lung Res 2002;28:55-68.
    • (2002) Exp Lung Res , vol.28 , pp. 55-68
    • John, M.1    Oltmanns, U.2    Fietze, I.3    Witt, C.4    Jung, K.5
  • 36
    • 0033669058 scopus 로고    scopus 로고
    • Differential regulation of metalloproteinase production, proliferation and chemotaxis of human lung fibroblasts by PDGF, interleukin-1beta and TNF-alpha
    • Sasaki M, Kashima M, Ito T, Watanabe A, Izumiyama N, Sano M, et al. Differential regulation of metalloproteinase production, proliferation and chemotaxis of human lung fibroblasts by PDGF, interleukin-1beta and TNF-alpha. Mediators Inflamm 2000;9:155-60.
    • (2000) Mediators Inflamm , vol.9 , pp. 155-160
    • Sasaki, M.1    Kashima, M.2    Ito, T.3    Watanabe, A.4    Izumiyama, N.5    Sano, M.6
  • 37
    • 0026010305 scopus 로고
    • Transforming growth factor beta 1 is present at sites of extracellular matrix gene expression in human pulmonary fibrosis
    • Broekelmann TJ, Limper AH, Colby TV, McDonald JA. Transforming growth factor beta 1 is present at sites of extracellular matrix gene expression in human pulmonary fibrosis. Proc Natl Acad Sci U S A 1991;88:6642-6.
    • (1991) Proc Natl Acad Sci U S A , vol.88 , pp. 6642-6646
    • Broekelmann, T.J.1    Limper, A.H.2    Colby, T.V.3    McDonald, J.A.4
  • 39
    • 26244458018 scopus 로고    scopus 로고
    • TGF-beta1 induces human alveolar epithelial to mesenchymal cell transition (EMT)
    • Kasai H, Allen JT, Mason RM, Kamimura T, Zhang Z. TGF-beta1 induces human alveolar epithelial to mesenchymal cell transition (EMT). Respir Res 2005;6:56.
    • (2005) Respir Res , vol.6 , pp. 56
    • Kasai, H.1    Allen, J.T.2    Mason, R.M.3    Kamimura, T.4    Zhang, Z.5
  • 40
    • 0041810531 scopus 로고    scopus 로고
    • Cytokine profiles in idiopathic pulmonary fibrosis suggest an important role for TGF-beta and IL-10
    • Bergeron A, Soler P, Kambouchner M, Loiseau P, Milleron B, Valeyre D, et al. Cytokine profiles in idiopathic pulmonary fibrosis suggest an important role for TGF-beta and IL-10. Eur Respir J 2003;22:69-76.
    • (2003) Eur Respir J , vol.22 , pp. 69-76
    • Bergeron, A.1    Soler, P.2    Kambouchner, M.3    Loiseau, P.4    Milleron, B.5    Valeyre, D.6
  • 41
    • 0026082056 scopus 로고
    • Interleukin-8 (IL-8): The major neutrophil chemotactic factor in the lung
    • Kunkel SL, Standiford T, Kasahara K, Strieter RM. Interleukin-8 (IL-8): the major neutrophil chemotactic factor in the lung. Exp Lung Res 1991;17:17-23.
    • (1991) Exp Lung Res , vol.17 , pp. 17-23
    • Kunkel, S.L.1    Standiford, T.2    Kasahara, K.3    Strieter, R.M.4
  • 42
    • 44949150434 scopus 로고    scopus 로고
    • TGF-betal transgenic mouse model of thoracic irradiation: Modulation of MMP-2 and MMP-9 in the lung tissue
    • Yang K, Liu L, Zhang T, Wu G, Puebe C, Ruebe C, et al. TGF-betal transgenic mouse model of thoracic irradiation: modulation of MMP-2 and MMP-9 in the lung tissue. J Huazhong Univ Sci Technolog Med Sci 2006;26:301-4.
    • (2006) J Huazhong Univ Sci Technolog Med Sci , vol.26 , pp. 301-304
    • Yang, K.1    Liu, L.2    Zhang, T.3    Wu, G.4    Puebe, C.5    Ruebe, C.6
  • 43
    • 0027715292 scopus 로고
    • Alveolar macrophage secretion of a 92-kDa gelatinase in response to bleomycin
    • Denholm EM, Rollins SM. Alveolar macrophage secretion of a 92-kDa gelatinase in response to bleomycin. Am J Physiol 1993;265:L581-5.
    • (1993) Am J Physiol , vol.265
    • Denholm, E.M.1    Rollins, S.M.2
  • 44
    • 0036256647 scopus 로고    scopus 로고
    • The role of matrix metalloproteinase-9 and tissue inhibitor of metalloproteinase-1 in cryptogenic organizing pneumonia
    • Choi KH, Lee HB, Jeong MY, Rhee YK, Chung MJ, Kwak YG, et al. The role of matrix metalloproteinase-9 and tissue inhibitor of metalloproteinase-1 in cryptogenic organizing pneumonia. Chest 2002;121:1478-85.
    • (2002) Chest , vol.121 , pp. 1478-1485
    • Choi, K.H.1    Lee, H.B.2    Jeong, M.Y.3    Rhee, Y.K.4    Chung, M.J.5    Kwak, Y.G.6
  • 45
    • 0035069059 scopus 로고    scopus 로고
    • Inhibition of bleomycin-induced pulmonary fibrosis in mice by the matrix metalloproteinase inhibitor batimastat
    • Corbel M, Caulet-Maugendre S, Germain N, Molet S, Lagente V, Boichot E. Inhibition of bleomycin-induced pulmonary fibrosis in mice by the matrix metalloproteinase inhibitor batimastat. J Pathol 2001;193:538-45.
    • (2001) J Pathol , vol.193 , pp. 538-545
    • Corbel, M.1    Caulet-Maugendre, S.2    Germain, N.3    Molet, S.4    Lagente, V.5    Boichot, E.6
  • 46
    • 0037329252 scopus 로고    scopus 로고
    • Imbalance between matrix metalloproteinases (MMP-9 and MMP-2) and tissue inhibitors of metalloproteinases (TIMP-1 and TIMP-2) in acute respiratory distress syndrome patients
    • Lanchou J, Corbel M, Tanguy M, Germain N, Boichot E, Theret N, et al. Imbalance between matrix metalloproteinases (MMP-9 and MMP-2) and tissue inhibitors of metalloproteinases (TIMP-1 and TIMP-2) in acute respiratory distress syndrome patients. Crit Care Med 2003;31:536-42.
    • (2003) Crit Care Med , vol.31 , pp. 536-542
    • Lanchou, J.1    Corbel, M.2    Tanguy, M.3    Germain, N.4    Boichot, E.5    Theret, N.6


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