The role of selective nitric oxide synthase inhibitor on nitric oxide and PGE 2 levels in refractory hemorrhagic-shocked rats

Journal of Surgical Research

Volumn 123, Issue 2, 2005, Pages 206-214

  Md, Shirhan ^a   Moochhala, Shabbir M ^b,c   Yang, Kerwin Low Siew ^a   Lu, Jia ^b   Anuar, Farhana ^a   Mok, Pamela ^a   Ng, Kian Chye ^a  

^a NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^b Def Med Environ Res Inst DSO N   (Singapore)

^c Def Med Environ Res Inst DSO N   (Singapore)

Author keywords

aminoguanidine (AG); COX 2; iNOS; MABP; nitrate nitrite; rat; survival rates

Indexed keywords

AMINOGUANIDINE; ASPARTATE AMINOTRANSFERASE; CREATININE; CYCLOOXYGENASE 2; INDUCIBLE NITRIC OXIDE SYNTHASE; N (2 CYCLOHEXYLOXY 4 NITROPHENYL)METHANESULFONAMIDE; NITRATE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE INHIBITOR; NITRITE; PROSTAGLANDIN E2; PROSTANOID; REACTIVE OXYGEN METABOLITE; SODIUM CHLORIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN; COMPARATIVE STUDY; CONTROLLED STUDY; CREATININE BLOOD LEVEL; HEMORRHAGIC SHOCK; HISTOLOGY; KIDNEY; LUNG; MALE; MEAN ARTERIAL PRESSURE; NONHUMAN; ORGAN INJURY; PRIORITY JOURNAL; PROSTAGLANDIN BLOOD LEVEL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; RAT; SURVIVAL RATE; UPREGULATION;

ANIMALS; ASPARTATE AMINOTRANSFERASES; BLOOD PRESSURE; BRAIN; CREATININE; CYCLOOXYGENASE 2; CYCLOOXYGENASE 2 INHIBITORS; CYCLOOXYGENASE INHIBITORS; DINOPROSTONE; ENZYME INHIBITORS; GUANIDINES; IMMUNOBLOTTING; KIDNEY; LIVER; LUNG; MALE; NISSL BODIES; NITRATES; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE TYPE II; NITRITES; NITROBENZENES; PROSTAGLANDIN-ENDOPEROXIDE SYNTHASES; RATS; RATS, SPRAGUE-DAWLEY; SHOCK, HEMORRHAGIC; SULFONAMIDES; SURVIVAL RATE;

EID: 13244288750     PISSN: 00224804     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jss.2004.07.243     Document Type: Article

References (52)

1. T.C. Hua, S.M. Moochhala Influence of l-arginine, aminoguanidine, and NG-nitro-l-arginine methyl ester (l-NAME) on the survival rate in a rat model of hemorrhagic shock Shock 11 1999 51
2. C. Thiemermann, C. Szabo, J.A. Mitchel Vascular hyporeactivity to vasoconstrictor agents and hemodynamic decompensation in hemorrhagic shock is mediated by nitric oxide Proc. Natl. Acad. Sci. USA 90 1993 267
3. R. Anaya-Prado, L.H. Toledo-Pereyra, R.F. Guo The attenuation of hemorrhage-induced liver injury by exogenous nitric oxide, Larginine, and inhibition of inducible nitric oxide synthase J. Invest. Surg. 16 2003 247
4. M. McDonald, M. Abdelrahman, S. Cuzzocrea Tyrphostin reduces the organ injury in haemorrhagic shock role of inducible nitric oxide synthase Resuscitation 58 2003 349
5. D. Ungureanu-Longrois, J.L. Balligand, R.A. Kelly Myocardial contractile dysfunction in the systemic inflammatory response syndrome role of a cytokine-inducible nitric oxide synthase in cardiac myocytes J. Mol. Cell. Cardiol. 27 1995 155
6. B.G. Harbrecht, T.R. Billiar, J. Stadler Nitric oxide synthesis serves to reduce hepatic damage during acute murine endotoxemia Crit. Care Med. 20 1992 1568
7. A. Petros, G. Lamb, A. Leone Effects of a nitric oxide synthase inhibitor in humans with septic shock Cardiovasc. Res. 28 1994 34
8. P. Vallance, S. Moncada Role of endogenous nitric oxide in septic shock New Horiz. 1 1993 77
9. S.A. Grosjean, M.A. Arstall, R.N. Mitchell Inducible nitric oxide synthase and tumor necrosis factor in animal models of myocardial necrosis induced by coronary artery ligation or isoproterenol injection J. Card. Fail. 5 1999 236
10. J.L. Collins, Y. Vodovotz, C. Hierholzer Characterization of the expression of inducible nitric oxide synthase in rat and human liver during hemorrhagic shock Shock 19 2003 117
11. J.M. Menezes, C. Hierholzer, S.C. Watkins The modulation of hepatic injury and heat shock expression by inhibition of inducible nitric oxide synthase after hemorrhagic shock Shock 17 2002 13
12. C. Hierholzer, J.M. Menezes, A. Ungeheuer A Nitric oxide scavenger protects against pulmonary inflammation following hemorrhagic shock Shock 17 2002 98
13. T.H. Liu, E.K. Robinson, K.S. Helmer Does upregulation of inducible nitric oxide synthase play a role in hepatic injury? Shock 18 2002 549
14. S. Cuzzocrea, P.K. Chatterjee, E. Mazzon Role of induced nitric oxide in the initiation of the inflammatory response after postischemic injury Shock 18 2002 169
15. C. Pozzilli, G.L. Lenzi, C. Argentino Imaging of leukocytic infiltration in human cerebral infarcts Stroke 16 1985 251
16. W.M. Clark, K.P. Madden, R. Rothlein Reduction of central nervous system ischemic injury in rabbits using leukocyte adhesion antibody treatment Stroke 22 1991 877
17. H. Chen, M. Chopp, G. Bodzin Neutropenia reduces the volume of cerebral infarct after transient middle cerebral artery occlusion in the rat Neurosci. Res. Commun. 11 1992 93
18. H. Chen, M. Chopp, R.L. Zhang Anti-CD11b monoclonal antibody reduces ischemic cell damage after transient focal cerebral ischemia in rat Ann. Neurol. 35 1994 458
19. G.Z. Feuerstein, X. Wang, F.C. Barone The role of cytokines in the neuropathology of stroke and neurotrauma review Neuroimmunomodulation 5 1998 143
20. C. Iadecola Bright and dark side of nitric oxide in ischemic brain damage Trends Neurosci. 20 1997 132
21. K. Tsukada, T. Hasegawa, S. Tsutsumi Role of cyclooxygenase-2 in tissue injury during hemorrhagic shock Shock 13 2000 392
22. M.W. Knoferl, M.D. Diodato, M.G. Schwacha Cyclooxygenase-2-mediated regulation of kupffer cell interleukin-6 production following trauma-hemorrhage and subsequent sepsis Shock 16 2001 479
23. R.N. Dubois, S. Abramson, B.L. Crofford Cyclooxygenase in biology and disease FASEB J. 12 1998 1063
24. 2 Crit. Rev. Immunol. 17 1997 225
25. J.R. Vane, Y.S. Bakhle, R.M. Botting Cyclooxygenases 1 and 2 Annu. Rev. Pharmacol. Toxicol. 38 1998 97
26. W.L. Smith, D.L. DeWitt, R.M. Garavito Cyclooxygenases structural, cellular, and molecular biology Annu. Rev. Biochem. 69 2000 145
27. S. Nogawa, F. Zhang, M.E. Ross Cyclooxygenae-2 gene expression in neurons contributes to ischemic brain damage J. Neurosci. 17 1997 2746
28. S. Miettinen, F.R. Fusco, J. Yrjanheikki Spreading depression and focal brain ischemia induce cyclooxygenase-2 in cortical neurons through N-methyl-d-aspartic acidreceptors and phospholipase A2 Proc. Natl. Acad. Sci. USA 94 1997 6500
29. A.M. Planas, M.A. Soriano, E. Rodriguez-Farre Induction of cyclooxygenase-2 mRNA and protein following transient focal ischemia in the rat brain Neurosci. Lett. 200 1995 187
30. Y. Collaco-Moraes, B. Aspey, M. Harrison Cyclo-oxygenase-2 messenger RNA induction in focal cerebral ischemia J. Cereb. Blood Flow Metab. 16 1996 1366
31. D.C. Goodwin, L.M. Landino, L.J. Marnett Effects of nitric oxide and nitric oxide derived species on prostaglandin endoperoxide synthase and prostaglandin biosynthesis FASEB J. 13 1999 1121
32. H. Okamoto, O. Ito, R.J. Roman Role of inducible nitric oxide synthase and cyclooxygenase-2 in endotoxin-induced cerebral hyperemia Stroke 29 1998 1209
33. S. Moncada, A. Higgs The l-arginine-nitric oxide pathway N. Engl. J. Med. 329 1993 2002
34. D. Salvemini, T.P. Misko, J.L. Masferrer Nitric oxide activates cyclooxygenase enzymes Proc. Natl Acad. Sci. USA 90 1993 7240
35. S. Nogawa, C. Forster, F. Zhang Interaction between inducible nitric oxide synthase and cyclooxygenase-2 after cerebral ischemia Proc. Natl Acad. Sci. USA 95 1998 10966
36. 15N] nitrate in biological fluids Anal. Biochem. 126 1982 131
37. M.M. Bradford A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding Anal. Biochem. 72 1976 248
38. G.J. Southan, C. Szabó Selective pharmacological inhibition of distinct nitric oxide synthase isoforms Biochem. Pharmacol. 51 1996 383
39. W.R. Tracey, J. Tse, G. Carter Lipopolysaccharide-induced changes in plasma nitrite and nitrate concentrations in rats and mice pharmacological evaluation of nitric oxide synthase inhibitors J. Pharmacol. Exp. Ther. 272 1995 1011
40. J.A. Corbett, R.G. Tilton, K. Chang Aminoguanidine, a novel inhibitor of nitric oxide formation, prevents diabetic vascular dysfunction Diabetes 41 1992 552
41. M.J. Griffiths, M. Messent, R.J. MacAllister Aminoguanidine selectively inhibits inducible nitric oxide synthase Br. J. Pharmacol. 110 1993 963
42. O.W. Griffith, S.S. Gross Inhibitors of nitric oxide synthases M. Feelisch J. Stamler Methods in Nitric Oxide Research 187 1996 Wiley Chichester, UK
43. J. Wood, J. Garthwaite Models of the diffusional spread of nitric oxide implications for neural nitric oxide signaling and its pharmacological properties Neuropharmacology 33 1994 1235
44. C.C. Chao, S. Hu, T.W. Molitor Activated microglia mediate neuronal cell injury via a nitric oxide mechanism J. Immunol. 149 1992 2736
45. S.J. Hewett, C.A. Csernansky, D.W. Choi Selective potentiation of NMDA-induced neuronal injury following induction of astrocytic iNOS Neuron 13 1994 487
46. V.L. Dawson, H.P. Brahmbhatt, J.A. Mong Expression of inducible nitric oxide synthase causes delayed neurotoxicity in primary mixed neuronalglial cortical cultures Neuropharmacology 33 1994 1425
47. K.K. Wu Inducible cyclooxygenase and nitric oxide synthase Adv. Pharmacol. 33 1995 179
48. H.A. Kontos, E.P. Wei, J.T. Povlishock Cerebral arteriolar damage by arachidonic acid and prostaglandin G2 Science 209 1980 1242
49. K. Seibert, J. Masferrer, Y. Zhang Expression and selective inhibition of constitutive and inducible forms of cyclooxygenase Agents Actions 46 Suppl 1995 41
50. K.C. Ng, S.M. Moochhala, Md. Shirhan Preservation of neurological functions by nitric oxide synthase inhibitors following hemorrhagic shock Neuropharmacology 44 2003 244
51. C. Vanlersberghe, M.H. Lauwers, F. Camu Prostaglandin synthetase inhibitor treatment and the regualtory role of prostagalandins on organ perfusion Acta Anaesthesiologica Belgica 43 1992 211
52. G. Gong, S.R. Ennis, J.T. Hoff Inducible cyclooxygenase-2 expression after experimental intracerebral hemorrhage Brain Res. 901 2001 38