메뉴 건너뛰기




Volumn 17, Issue 6, 2012, Pages 634-639

Chronic renal allograft damage after transplantation: What are the reasons, what can we do?

Author keywords

chronic rejection; chronic renal allograft damage; intestitial fibrosis tubular atrophy; therapy

Indexed keywords

ALLOANTIGEN; ANGIOTENSIN 1 RECEPTOR; BELATACEPT; CALCINEURIN INHIBITOR; CYCLOSPORIN; CYTOCHROME P450 2C8; CYTOCHROME P450 3A5; DOPAMINE; FICOLIN; KIDNEY INJURY MOLECULE 1; LEUKOCYTE ANTIBODY; MAMMALIAN TARGET OF RAPAMYCIN INHIBITOR; MANNOSE BINDING LECTIN 2; METALLOPROTEINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; MULTIDRUG RESISTANCE PROTEIN 1; NEUTROPHIL GELATINASE ASSOCIATED LIPOCALIN; PRASTERONE; TACROLIMUS; TRANSFORMING GROWTH FACTOR BETA;

EID: 84870255948     PISSN: 10872418     EISSN: 15317013     Source Type: Journal    
DOI: 10.1097/MOT.0b013e32835a4bfa     Document Type: Review
Times cited : (16)

References (84)
  • 1
    • 0014201129 scopus 로고
    • Proteinuria and nephrotic syndrome associated with chronic rejection of kidney transplants
    • Harlan WR Jr, Holden KR, Williams GM, Hume DM. Proteinuria and nephrotic syndrome associated with chronic rejection of kidney transplants. N Engl J Med 1967; 277:769-776.
    • (1967) N Engl J Med , vol.277 , pp. 769-776
    • Harlan Jr., W.R.1    Holden, K.R.2    Williams, G.M.3    Hume, D.M.4
  • 4
    • 0028043866 scopus 로고
    • Long-term kidney isografts develop functional and morphologic changes that mimic those of chronic allograft rejection
    • discussion 32-35
    • Tullius SG, Heemann U, Hancock WW, et al. Long-term kidney isografts develop functional and morphologic changes that mimic those of chronic allograft rejection. Ann Surg 1994; 220:425-432; discussion 32-35.
    • (1994) Ann Surg , vol.220 , pp. 425-432
    • Tullius, S.G.1    Heemann, U.2    Hancock, W.W.3
  • 6
    • 84866333284 scopus 로고    scopus 로고
    • Kidneys from older living donors provide excellent intermediate-term outcomes after transplantation
    • Balachandran VP, Aull MJ, Charlton M, et al. Kidneys from older living donors provide excellent intermediate-term outcomes after transplantation. Transplantation 2012; 94:499-505.
    • (2012) Transplantation , vol.94 , pp. 499-505
    • Balachandran, V.P.1    Aull, M.J.2    Charlton, M.3
  • 7
    • 84864111634 scopus 로고    scopus 로고
    • Kidney transplantation: A 46-year experience from the transplant institute, sahlgrenska university hospital, gothenburg, sweden
    • Friman S, Norden G, Lennerling A, et al. Kidney transplantation: a 46-year experience from the Transplant Institute, Sahlgrenska University Hospital, Gothenburg, Sweden. Clin Transpl 2011; 2011:119-125.
    • (2011) Clin Transpl , vol.2011 , pp. 119-125
    • Friman, S.1    Norden, G.2    Lennerling, A.3
  • 10
    • 80054727578 scopus 로고    scopus 로고
    • Duration of brain death and cold ischemia time, but not warm ischemia time, increases expression of genes associated with apoptosis in transplanted kidneys from deceased donors
    • lznerowicz A, Chudoba P, Kaminska D, et al. Duration of brain death and cold ischemia time, but not warm ischemia time, increases expression of genes associated with apoptosis in transplanted kidneys from deceased donors. Transplant Proc 2011; 43:2887-2890.
    • (2011) Transplant Proc , vol.43 , pp. 2887-2890
    • Lznerowicz, A.1    Chudoba, P.2    Kaminska, D.3
  • 12
    • 0032429362 scopus 로고    scopus 로고
    • Ischemia reperfusion injury and chronic allograft rejection
    • DOI 10.1016/S0041-1345(98)01414-6, PII S0041134598014146
    • Szabo A, Heemann U. Ischemia reperfusion injury and chronic allograft rejection. Transplant Proc 1998; 30:4281-4284. (Pubitemid 29013225)
    • (1998) Transplantation Proceedings , vol.30 , Issue.8 , pp. 4281-4284
    • Szabo, A.1    Heemann, U.2
  • 13
    • 80054765886 scopus 로고    scopus 로고
    • Kidney ischemic injury genes expressed after donor brain death are predictive for the outcome of kidney transplantation
    • Kaminska D, Koscielska-Kasprzak K, Drulis-Fajdasz D, et al. Kidney ischemic injury genes expressed after donor brain death are predictive for the outcome of kidney transplantation. Transplant Proc 2011; 43:2891-2894.
    • (2011) Transplant Proc , vol.43 , pp. 2891-2894
    • Kaminska, D.1    Koscielska-Kasprzak, K.2    Drulis-Fajdasz, D.3
  • 14
    • 78651075852 scopus 로고    scopus 로고
    • Molecular biomarker candidates of acute kidney injury in zero-hour renal transplant needle biopsies
    • Korbely R, Wilflingseder J, Perco P, et al. Molecular biomarker candidates of acute kidney injury in zero-hour renal transplant needle biopsies. Transpl Int 2011; 24:143-149.
    • (2011) Transpl Int , vol.24 , pp. 143-149
    • Korbely, R.1    Wilflingseder, J.2    Perco, P.3
  • 15
    • 84866743569 scopus 로고    scopus 로고
    • TLR4 mRNA levels as tools to estimate risk for early posttransplantation kidney graft dysfunction
    • Andrade-Oliveira V, Campos EF, Goncalves-Primo A, et al. TLR4 mRNA levels as tools to estimate risk for early posttransplantation kidney graft dysfunction. Transplantation 2012; 94:589-595.
    • (2012) Transplantation , vol.94 , pp. 589-595
    • Andrade-Oliveira, V.1    Campos, E.F.2    Goncalves-Primo, A.3
  • 16
    • 66249147277 scopus 로고
    • Successful homotransplantation of the human kidney between identical twins
    • Merrill JP, Murray JE, Harrison JH, Guild WR. Successful homotransplantation of the human kidney between identical twins. J Am Med Assoc 1956; 160:277-282.
    • (1956) J Am Med Assoc , vol.160 , pp. 277-282
    • Merrill, J.P.1    Murray, J.E.2    Harrison, J.H.3    Guild, W.R.4
  • 17
    • 0022913117 scopus 로고
    • Renal transplantation between identical twins: A review
    • Tilney NL. Renal transplantation between identical twins: a review. World J Surg 1986; 10:381-388.
    • (1986) World J Surg , vol.10 , pp. 381-388
    • Tilney, N.L.1
  • 18
    • 0020358881 scopus 로고
    • Late mortality and morbidity in recipients of long-term renal allografts
    • Kirkman RL, Strom TB, Weir MR, Tilney NL. Late mortality and morbidity in recipients of long-term renal allografts. Transplantation 1982; 34:347-351. (Pubitemid 13170993)
    • (1982) Transplantation , vol.34 , Issue.6 , pp. 347-351
    • Kirkman, R.L.1    Strom, T.B.2    Weir, M.R.3    Tilney, N.L.4
  • 19
    • 58149356748 scopus 로고    scopus 로고
    • Renal transplantation in identical twins in cunited States and United Kingdom
    • Kessaris N, Mukherjee D, Chandak P, Mamode N. Renal transplantation in identical twins in United States and United Kingdom. Transplantation 2008; 86:1572-1577.
    • (2008) Transplantation , vol.86 , pp. 1572-1577
    • Kessaris, N.1    Mukherjee, D.2    Chandak, P.3    Mamode, N.4
  • 20
    • 84855414378 scopus 로고    scopus 로고
    • Antibodies to HLA-E may account for the nondonor-specific anti-HLA class-ia antibodies in renal and liver transplant recipients
    • Ravindranath MH, Pham T, Ozawa M, Terasaki PI. Antibodies to HLA-E may account for the nondonor-specific anti-HLA class-Ia antibodies in renal and liver transplant recipients. Int Immunol 2012; 24:43-57.
    • (2012) Int Immunol , vol.24 , pp. 43-57
    • Ravindranath, M.H.1    Pham, T.2    Ozawa, M.3    Terasaki, P.I.4
  • 21
    • 84860473178 scopus 로고    scopus 로고
    • Evolution and clinical pathologic correlations of de novo donor-specific HLA antibody post kidney transplant
    • Wiebe C, Gibson IW, Blydt-Hansen TD, et al. Evolution and clinical pathologic correlations of de novo donor-specific HLA antibody post kidney transplant. Am J Transplant 2012; 12:1157-1167.
    • (2012) Am J Transplant , vol.12 , pp. 1157-1167
    • Wiebe, C.1    Gibson, I.W.2    Blydt-Hansen, T.D.3
  • 22
    • 84869071750 scopus 로고    scopus 로고
    • Non-HLA-antibodies targeting angiotensin type 1 receptor and antibody mediated rejection
    • [Epub ahead of print]
    • Dragun D, Catar R, Kusch A, et al. Non-HLA-antibodies targeting angiotensin type 1 receptor and antibody mediated rejection. Human Immunol 2012. [Epub ahead of print]
    • (2012) Human Immunol
    • Dragun, D.1    Catar, R.2    Kusch, A.3
  • 24
    • 84866342272 scopus 로고    scopus 로고
    • The functional polymorphism ala258ser in the innate receptor gene ficolin-2 in the donor predicts improved renal transplant outcome
    • Eikmans M, de Canck I, van der Pol P, et al. The functional polymorphism Ala258Ser in the innate receptor gene Ficolin-2 in the donor predicts improved renal transplant outcome. Transplantation 2012; 94:478-485.
    • (2012) Transplantation , vol.94 , pp. 478-485
    • Eikmans, M.1    De Canck, I.2    Van Der Pol, P.3
  • 25
    • 84867631834 scopus 로고    scopus 로고
    • Role of mannose-binding lectin-2 polymorphism in the development of acute cellular rejection after transplantation for hepatitis C virus-induced liver disease
    • Eurich D, Boas-Knoop S, Yahyazadeh A, et al. Role of mannose-binding lectin-2 polymorphism in the development of acute cellular rejection after transplantation for hepatitis C virus-induced liver disease. Transplant Infect Dis 2012; 14:488-495.
    • (2012) Transplant Infect Dis , vol.14 , pp. 488-495
    • Eurich, D.1    Boas-Knoop, S.2    Yahyazadeh, A.3
  • 26
    • 84858684409 scopus 로고    scopus 로고
    • Role of IL28B polymorphism in the development of hepatitis C virus-induced hepatocellular carcinoma, graft fibrosis, and posttransplant antiviral therapy
    • Eurich D, Boas-Knoop S, Bahra M, et al. Role of IL28B polymorphism in the development of hepatitis C virus-induced hepatocellular carcinoma, graft fibrosis, and posttransplant antiviral therapy. Transplantation 2012; 93:644-649.
    • (2012) Transplantation , vol.93 , pp. 644-649
    • Eurich, D.1    Boas-Knoop, S.2    Bahra, M.3
  • 27
    • 0028676679 scopus 로고
    • Alloantigen-independent factors lead to signs of chronic rejection in long-term kidney isografts
    • Tullius SG, Heemann UW, Azuma H, et al. Alloantigen-independent factors lead to signs of chronic rejection in long-term kidney isografts. Transplant Int 1994; 7 (Suppl 1):S306-S307.
    • (1994) Transplant Int , vol.7 , Issue.SUPPL. 1
    • Tullius, S.G.1    Heemann, U.W.2    Azuma, H.3
  • 28
    • 0028569493 scopus 로고
    • Late-acute renal allograft rejection and symptomless cytomegalovirus infection
    • Reinke P, Fietze E, Ode-Hakim S, et al. Late-acute renal allograft rejection and symptomless cytomegalovirus infection. Lancet 1994; 344:1737-1738.
    • (1994) Lancet , vol.344 , pp. 1737-1738
    • Reinke, P.1    Fietze, E.2    Ode-Hakim, S.3
  • 31
    • 73649124549 scopus 로고    scopus 로고
    • Chronic calcineurin inhibitor nephrotoxicity: Reflections on an evolving paradigm
    • Gaston RS. Chronic calcineurin inhibitor nephrotoxicity: reflections on an evolving paradigm. Clin J Am Soc Nephrol 2009; 4:2029-2034.
    • (2009) Clin J Am Soc Nephrol , vol.4 , pp. 2029-2034
    • Gaston, R.S.1
  • 32
    • 84856521251 scopus 로고    scopus 로고
    • Inhibition of TLR2 promotes graft function in a murine model of renal transplant ischemia-reperfusion injury
    • Farrar CA, Keogh B, McCormack W, et al. Inhibition of TLR2 promotes graft function in a murine model of renal transplant ischemia-reperfusion injury. FASEB J 2012; 26:799-807.
    • (2012) FASEB J , vol.26 , pp. 799-807
    • Farrar, C.A.1    Keogh, B.2    McCormack, W.3
  • 33
    • 84859767406 scopus 로고    scopus 로고
    • Toll-like receptors in transplantation: Sensing and reacting to injury
    • Leventhal JS, Schroppel B. Toll-like receptors in transplantation: sensing and reacting to injury. Kidney Int 2012; 81:826-832.
    • (2012) Kidney Int , vol.81 , pp. 826-832
    • Leventhal, J.S.1    Schroppel, B.2
  • 34
    • 82455164107 scopus 로고    scopus 로고
    • Progressive histological damage in renal allografts is associated with expression of innate and adaptive immunity genes
    • Naesens M, Khatri P, Li L, et al. Progressive histological damage in renal allografts is associated with expression of innate and adaptive immunity genes. Kidney Int 2011; 80:1364-1376.
    • (2011) Kidney Int , vol.80 , pp. 1364-1376
    • Naesens, M.1    Khatri, P.2    Li, L.3
  • 35
    • 84864582036 scopus 로고    scopus 로고
    • Cold ischaemia, innate immunity and deterioration of the glomerular filtration barrier in antibody-mediated acute rejection
    • Ripoll E, Nacher V, Vidal A, et al. Cold ischaemia, innate immunity and deterioration of the glomerular filtration barrier in antibody-mediated acute rejection. Nephrol Dial Transplant 2012; 27:3296-3305.
    • (2012) Nephrol Dial Transplant , vol.27 , pp. 3296-3305
    • Ripoll, E.1    Nacher, V.2    Vidal, A.3
  • 36
    • 84859858471 scopus 로고    scopus 로고
    • Non-HLA antibodies to immunogenic epitopes predict the evolution of chronic renal allograft injury
    • Sigdel TK, Li L, Tran TQ, et al. Non-HLA antibodies to immunogenic epitopes predict the evolution of chronic renal allograft injury. J Am Soc Nephrol 2012; 23:750-763.
    • (2012) J Am Soc Nephrol , vol.23 , pp. 750-763
    • Sigdel, T.K.1    Li, L.2    Tran, T.Q.3
  • 37
    • 84863198325 scopus 로고    scopus 로고
    • Long-term histopathology of allografts in sensitized kidney recipients
    • Miura M, Harada H, Fukasawa Y, et al. Long-term histopathology of allografts in sensitized kidney recipients. Clin Transplant 2012; 26 (Suppl 24):32-36.
    • (2012) Clin Transplant , vol.26 , Issue.SUPPL. 24 , pp. 32-36
    • Miura, M.1    Harada, H.2    Fukasawa, Y.3
  • 38
    • 84859483971 scopus 로고    scopus 로고
    • Interstitial fibrosis and tubular atrophy on protocol biopsies at 1 year after renal transplantation
    • Yokoyama T, Konno O, Nakamura Y, et al. Interstitial fibrosis and tubular atrophy on protocol biopsies at 1 year after renal transplantation. Transplant Proc 2012; 44:607-609.
    • (2012) Transplant Proc , vol.44 , pp. 607-609
    • Yokoyama, T.1    Konno, O.2    Nakamura, Y.3
  • 39
    • 84860140162 scopus 로고    scopus 로고
    • The impact of pretransplant donor-specific antibodies on graft outcome in renal transplantation: A six-year follow-up study
    • David-Neto E, Souza PS, Panajotopoulos N, et al. The impact of pretransplant donor-specific antibodies on graft outcome in renal transplantation: a six-year follow-up study. Clinics 2012; 67:355-361.
    • (2012) Clinics , vol.67 , pp. 355-361
    • David-Neto, E.1    Souza, P.S.2    Panajotopoulos, N.3
  • 40
    • 77955607610 scopus 로고    scopus 로고
    • Preexisting donor-specific HLA antibodies predict outcome in kidney transplantation
    • Lefaucheur C, Loupy A, Hill GS, et al. Preexisting donor-specific HLA antibodies predict outcome in kidney transplantation. J Am Soc Nephrol 2010; 21:1398-1406.
    • (2010) J Am Soc Nephrol , vol.21 , pp. 1398-1406
    • Lefaucheur, C.1    Loupy, A.2    Hill, G.S.3
  • 41
    • 84868115525 scopus 로고    scopus 로고
    • Progressive graft fibrosis and donor-specific HLA antibodies in pediatric late liver allografts
    • doi: 10.1002/lt.23534. [Epub ahead of print]
    • Miyagawa-Hayashino A, Yoshizawa A, Uchida Y, et al. Progressive graft fibrosis and donor-specific HLA antibodies in pediatric late liver allografts. Liver Transplant 2012. doi: 10.1002/lt.23534. [Epub ahead of print]
    • (2012) Liver Transplant
    • Miyagawa-Hayashino, A.1    Yoshizawa, A.2    Uchida, Y.3
  • 42
    • 0027955866 scopus 로고
    • Tolerance to discordant xenografts: Sharing of human natural antibody determinants on miniature swine bone marrow cells and endothelial cells
    • Latinne D, Vitiello DM, Sachs DH, Sykes M. Tolerance to discordant xenografts. I. Sharing of human natural antibody determinants on miniature swine bone marrow cells and endothelial cells. Transplantation 1994; 57:238-245. (Pubitemid 24048592)
    • (1994) Transplantation , vol.57 , Issue.2 , pp. 238-245
    • Latinne, D.1    Vitiello, D.M.2    Sachs, D.H.3    Sykes, M.4
  • 43
    • 84858717283 scopus 로고    scopus 로고
    • Successful transplantation across positive B-cell cross-match in deceased donor renal transplants
    • Goh A, Oei E, Vathsala A. Successful transplantation across positive B-cell cross-match in deceased donor renal transplants. Transplant Proc 2012; 44:193-199.
    • (2012) Transplant Proc , vol.44 , pp. 193-199
    • Goh, A.1    Oei, E.2    Vathsala, A.3
  • 44
    • 84867553322 scopus 로고    scopus 로고
    • Renal transplantation in sensitized recipients with positive luminex and negative CDC (complement-dependent cytotoxicity) crossmatches
    • doi: 10.1111/j.1432-2277.2012.01543.x. [Epub ahead of print]
    • Huh KH, Kim MS, Kim HJ, et al. Renal transplantation in sensitized recipients with positive luminex and negative CDC (complement-dependent cytotoxicity) crossmatches. Transplant Int 2012. doi: 10.1111/j.1432-2277.2012. 01543.x. [Epub ahead of print]
    • (2012) Transplant Int
    • Huh, K.H.1    Kim, M.S.2    Kim, H.J.3
  • 45
    • 84861729701 scopus 로고    scopus 로고
    • Innovative strategies in living donor kidney transplantation
    • Segev DL. Innovative strategies in living donor kidney transplantation. Nat Rev Nephrol 2012; 8:332-338.
    • (2012) Nat Rev Nephrol , vol.8 , pp. 332-338
    • Segev, D.L.1
  • 46
    • 60649108279 scopus 로고    scopus 로고
    • Acute antibody-mediated rejection in living ABO-incompatible kidney transplantation: Long-term impact and risk factors
    • Toki D, Ishida H, Setoguchi K, et al. Acute antibody-mediated rejection in living ABO-incompatible kidney transplantation: long-term impact and risk factors. Am J Transplant 2009; 9:567-577.
    • (2009) Am J Transplant , vol.9 , pp. 567-577
    • Toki, D.1    Ishida, H.2    Setoguchi, K.3
  • 47
    • 79959683332 scopus 로고    scopus 로고
    • Decrease of blood type antigenicity over the long-term after ABO-incompatible kidney transplantation
    • Tanabe T, Ishida H, Horita S, et al. Decrease of blood type antigenicity over the long-term after ABO-incompatible kidney transplantation. Transplant Immunol 2011; 25:1-6.
    • (2011) Transplant Immunol , vol.25 , pp. 1-6
    • Tanabe, T.1    Ishida, H.2    Horita, S.3
  • 48
    • 0034055332 scopus 로고    scopus 로고
    • SDZ-RAD prevents manifestation of chronic rejection in rat renal allografts
    • Viklicky O, Zou H, Muller V, et al. SDZ-RAD prevents manifestation of chronic rejection in rat renal allografts. Transplantation 2000; 69:497-502. (Pubitemid 30129579)
    • (2000) Transplantation , vol.69 , Issue.4 , pp. 497-502
    • Viklicky, O.1    Zou, H.2    Muller, V.3    Lacha, J.4    Szabo, A.5    Heemann, U.6
  • 49
    • 34147139494 scopus 로고    scopus 로고
    • The effect of FK778 on the progression of chronic allograft nephropathy in a rat model
    • DOI 10.1097/01.tp.0000255558.02582.ce, PII 0000789020070327000015
    • Lutz J, Huang H, Deng M, et al. The effect of FK778 on the progression of chronic allograft nephropathy in a rat model. Transplantation 2007; 83:741-746. (Pubitemid 46569192)
    • (2007) Transplantation , vol.83 , Issue.6 , pp. 741-746
    • Lutz, J.1    Huang, H.2    Deng, M.3    Wagner, B.4    Roos, M.5    Schmaderer, C.6    Strobl, M.7    Heemann, U.8
  • 50
    • 84866326257 scopus 로고    scopus 로고
    • Review of randomized clinical trials of donor management and organ preservation in deceased donors: Opportunities and issues
    • Dikdan GS, Mora-Esteves C, Koneru B. Review of randomized clinical trials of donor management and organ preservation in deceased donors: opportunities and issues. Transplantation 2012; 94:425-441.
    • (2012) Transplantation , vol.94 , pp. 425-441
    • Dikdan, G.S.1    Mora-Esteves, C.2    Koneru, B.3
  • 51
    • 70149122642 scopus 로고    scopus 로고
    • Effects of donor pretreatment with dopamine on graft function after kidney transplantation: A randomized controlled trial
    • Schnuelle P, Gottmann U, Hoeger S, et al. Effects of donor pretreatment with dopamine on graft function after kidney transplantation: a randomized controlled trial. JAMA 2009; 302:1067-1075.
    • (2009) JAMA , vol.302 , pp. 1067-1075
    • Schnuelle, P.1    Gottmann, U.2    Hoeger, S.3
  • 52
    • 84857424125 scopus 로고    scopus 로고
    • Machine perfusion or cold storage in deceased-donor kidney transplantation
    • Machine Preservation Trial Study G
    • Moers C, Pirenne J, Paul A, Ploeg RJ, Machine Preservation Trial Study G. Machine perfusion or cold storage in deceased-donor kidney transplantation. N Engl J Med 2012; 366:770-771.
    • (2012) N Engl J Med , vol.366 , pp. 770-771
    • Moers, C.1    Pirenne, J.2    Paul, A.3    Ploeg, R.J.4
  • 53
    • 0034656070 scopus 로고    scopus 로고
    • Cyclosporine A and azathioprine are equipotent in chronic kidney allograft rejection
    • Hamar P, Liu S, Viklicky O, et al. Cyclosporine A and azathioprine are equipotent in chronic kidney allograft rejection. Transplantation 2000; 69:1290-1295. (Pubitemid 30238713)
    • (2000) Transplantation , vol.69 , Issue.7 , pp. 1290-1295
    • Hamar, P.1    Liu, S.2    Viklicky, O.3    Szabo, A.4    Muller, V.5    Heemann, U.6
  • 55
    • 84859060783 scopus 로고    scopus 로고
    • Rapamycin ameliorates kidney fibrosis by inhibiting the activation of mTOR signaling in interstitial macrophages and myofibroblasts
    • Chen G, Chen H, Wang C, et al. Rapamycin ameliorates kidney fibrosis by inhibiting the activation of mTOR signaling in interstitial macrophages and myofibroblasts. PloS One 2012; 7:e33626.
    • (2012) PloS One , vol.7
    • Chen, G.1    Chen, H.2    Wang, C.3
  • 56
    • 84859396142 scopus 로고    scopus 로고
    • Conversion from everolimus with low-exposure cyclosporine to everolimus with mycophenolate sodium maintenance therapy in kidney transplant recipients: A randomized, open-label multicenter study
    • Albano L, Alamartine E, Toupance O, et al. Conversion from everolimus with low-exposure cyclosporine to everolimus with mycophenolate sodium maintenance therapy in kidney transplant recipients: a randomized, open-label multicenter study. Ann Transplant 2012; 17:58-67.
    • (2012) Ann Transplant , vol.17 , pp. 58-67
    • Albano, L.1    Alamartine, E.2    Toupance, O.3
  • 57
    • 0001184102 scopus 로고    scopus 로고
    • Effect of angiotensin-converting enzyme inhibition on growth factor mRNA in chronic renal allograft rejection in the rat
    • DOI 10.1046/j.1523-1755.2000.00926.x
    • Szabo A, Lutz J, Schleimer K, et al. Effect of angiotensin-converting enzyme inhibition on growth factor mRNA in chronic renal allograft rejection in the rat. Kidney Int 2000; 57:982-991. (Pubitemid 30434788)
    • (2000) Kidney International , vol.57 , Issue.3 , pp. 982-991
    • Szabo, A.1    Lutz, J.2    Schleimer, K.3    Antus, B.4    Hamar, P.5    Philipp, T.6    Heemann, U.7
  • 58
    • 84864085352 scopus 로고    scopus 로고
    • Valsartan inhibited HIF-1alpha pathway and attenuated renal interstitial fibrosis in streptozotocin-diabetic rats
    • Tang L, Yi R, Yang B, et al. Valsartan inhibited HIF-1alpha pathway and attenuated renal interstitial fibrosis in streptozotocin-diabetic rats. Diabetes Res Clin Pract 2012; 97:125-131.
    • (2012) Diabetes Res Clin Pract , vol.97 , pp. 125-131
    • Tang, L.1    Yi, R.2    Yang, B.3
  • 59
    • 84860296188 scopus 로고    scopus 로고
    • Loss of angiotensin-converting enzyme 2 enhances TGF-beta/Smad-mediated renal fibrosis and NF-kappaB-driven renal inflammation in a mouse model of obstructive nephropathy
    • Liu Z, Huang XR, Chen HY, et al. Loss of angiotensin-converting enzyme 2 enhances TGF-beta/Smad-mediated renal fibrosis and NF-kappaB-driven renal inflammation in a mouse model of obstructive nephropathy. Laboratory Invest 2012; 92:650-661.
    • (2012) Laboratory Invest , vol.92 , pp. 650-661
    • Liu, Z.1    Huang, X.R.2    Chen, H.Y.3
  • 60
    • 1942502227 scopus 로고    scopus 로고
    • Withdrawal of Cyclosporine or Tacrolimus after Addition of Mycophenolate Mofetil in Patients with Chronic Allograft Nephropathy
    • DOI 10.1111/j.1600-6143.2004.00404.x
    • Suwelack B, Gerhardt U, Hohage H. Withdrawal of cyclosporine or tacrolimus after addition of mycophenolate mofetil in patients with chronic allograft nephropathy. Am J Transplant 2004; 4:655-662. (Pubitemid 38523590)
    • (2004) American Journal of Transplantation , vol.4 , Issue.4 , pp. 655-662
    • Suwelack, B.1    Gerhardt, U.2    Hohage, H.3
  • 61
    • 84865080227 scopus 로고    scopus 로고
    • Changes in matrix metalloproteinases and their inhibitors in kidney transplant recipients
    • Ahmed AK, El Nahas AM, Johnson TS. Changes in matrix metalloproteinases and their inhibitors in kidney transplant recipients. Exp Clin Transplant 2012; 10:332-343.
    • (2012) Exp Clin Transplant , vol.10 , pp. 332-343
    • Ahmed, A.K.1    El Nahas, A.M.2    Johnson, T.S.3
  • 62
    • 84863109009 scopus 로고    scopus 로고
    • Mycophenolate mofetil and FK506 have different effects on kidney allograft fibrosis in rats that underwent chronic allograft nephropathy
    • Luo L, Sun Z, Wu W, Luo G. Mycophenolate mofetil and FK506 have different effects on kidney allograft fibrosis in rats that underwent chronic allograft nephropathy. BMC Nephrol 2012; 13:53.
    • (2012) BMC Nephrol , vol.13 , pp. 53
    • Luo, L.1    Sun, Z.2    Wu, W.3    Luo, G.4
  • 63
    • 84863534976 scopus 로고    scopus 로고
    • Mycophenolate mofetil inhibits macrophage infiltration and kidney fibrosis in long-term ischemia-reperfusion injury
    • Jiang S, Tang Q, Rong R, et al. Mycophenolate mofetil inhibits macrophage infiltration and kidney fibrosis in long-term ischemia-reperfusion injury. Eur J Pharmacol 2012; 688:56-61.
    • (2012) Eur J Pharmacol , vol.688 , pp. 56-61
    • Jiang, S.1    Tang, Q.2    Rong, R.3
  • 65
    • 84862245081 scopus 로고    scopus 로고
    • Adherence with immunosuppressive treatment after transplantation: Results from the french trial PREDICT
    • Dharancy S, Giral M, Tetaz R, et al. Adherence with immunosuppressive treatment after transplantation: results from the French trial PREDICT. Clin Transplant 2012; 26:E293-E299.
    • (2012) Clin Transplant , vol.26
    • Dharancy, S.1    Giral, M.2    Tetaz, R.3
  • 66
    • 84855778965 scopus 로고    scopus 로고
    • Infiltrating cellular pattern in kidney graft biopsies translates into forkhead box protein 3 up-regulation and p16INK4alpha senescence protein down-regulation in patients treated with belatacept compared to cyclosporin A
    • Furuzawa-Carballeda J, Lima G, Alberu J, et al. Infiltrating cellular pattern in kidney graft biopsies translates into forkhead box protein 3 up-regulation and p16INK4alpha senescence protein down-regulation in patients treated with belatacept compared to cyclosporin A. Clin Exp Immunol 2012; 167:330-337.
    • (2012) Clin Exp Immunol , vol.167 , pp. 330-337
    • Furuzawa-Carballeda, J.1    Lima, G.2    Alberu, J.3
  • 67
    • 84862212813 scopus 로고    scopus 로고
    • Belatacept: A new biological agent for maintenance immunosuppression in kidney transplantation
    • Arora S, Tangirala B, Osadchuk L, Sureshkumar KK. Belatacept: a new biological agent for maintenance immunosuppression in kidney transplantation. Expert Opin Biol Ther 2012; 12:965-979.
    • (2012) Expert Opin Biol Ther , vol.12 , pp. 965-979
    • Arora, S.1    Tangirala, B.2    Osadchuk, L.3    Sureshkumar, K.K.4
  • 68
    • 84857646161 scopus 로고    scopus 로고
    • Three-year outcomes from BENEFIT-EXT: A phase III study of belatacept versus cyclosporine in recipients of extended criteria donor kidneys
    • Pestana JO, Grinyo JM, Vanrenterghem Y, et al. Three-year outcomes from BENEFIT-EXT: a phase III study of belatacept versus cyclosporine in recipients of extended criteria donor kidneys. Am J Transplant 2012; 12:630-639.
    • (2012) Am J Transplant , vol.12 , pp. 630-639
    • Pestana, J.O.1    Grinyo, J.M.2    Vanrenterghem, Y.3
  • 69
    • 84860733269 scopus 로고    scopus 로고
    • Randomized trial comparing late concentration-controlled calcineurin inhibitor or mycophenolate mofetil withdrawal
    • Mourer JS, Hartigh J, van Zwet EW, et al. Randomized trial comparing late concentration-controlled calcineurin inhibitor or mycophenolate mofetil withdrawal. Transplantation 2012; 93:887-894.
    • (2012) Transplantation , vol.93 , pp. 887-894
    • Mourer, J.S.1    Hartigh, J.2    Van Zwet, E.W.3
  • 70
    • 84863309114 scopus 로고    scopus 로고
    • Pathogenesis of calcineurin inhibitor-induced hypertension
    • Hoorn EJ, Walsh SB, McCormick JA, et al. Pathogenesis of calcineurin inhibitor-induced hypertension. J Nephrol 2012; 25:269-275.
    • (2012) J Nephrol , vol.25 , pp. 269-275
    • Hoorn, E.J.1    Walsh, S.B.2    McCormick, J.A.3
  • 71
    • 84863876040 scopus 로고    scopus 로고
    • Neutralization of tumor necrosis factor-alpha reduces renal fibrosis and hypertension in rats with renal failure
    • Therrien FJ, Agharazii M, Lebel M, Lariviere R. Neutralization of tumor necrosis factor-alpha reduces renal fibrosis and hypertension in rats with renal failure. Am J Nephrol 2012; 36:151-161.
    • (2012) Am J Nephrol , vol.36 , pp. 151-161
    • Therrien, F.J.1    Agharazii, M.2    Lebel, M.3    Lariviere, R.4
  • 72
    • 84861021000 scopus 로고    scopus 로고
    • Development of structural kidney damage in spontaneously hypertensive rats
    • Hultstrom M. Development of structural kidney damage in spontaneously hypertensive rats. J Hypertens 2012; 30:1087-1091.
    • (2012) J Hypertens , vol.30 , pp. 1087-1091
    • Hultstrom, M.1
  • 73
    • 82855168152 scopus 로고    scopus 로고
    • Protective effect of TRPV1 against renal fibrosis via inhibition of TGF-beta/Smad signaling in DOCA-salt hypertension
    • Wang Y, Wang DH. Protective effect of TRPV1 against renal fibrosis via inhibition of TGF-beta/Smad signaling in DOCA-salt hypertension. Mol Med 2011; 17:1204-1212.
    • (2011) Mol Med , vol.17 , pp. 1204-1212
    • Wang, Y.1    Wang, D.H.2
  • 74
    • 0032894945 scopus 로고    scopus 로고
    • Sex hormones and gender-related differences: Their influence on chronic renal allograft rejection
    • DOI 10.1046/j.1523-1755.1999.00441.x
    • Muller V, Szabo A, Viklicky O, et al. Sex hormones and gender-related differences: their influence on chronic renal allograft rejection. Kidney Int 1999; 55:2011-2020. (Pubitemid 29197991)
    • (1999) Kidney International , vol.55 , Issue.5 , pp. 2011-2020
    • Muller, V.1    Szabo, A.2    Viklicky, O.3    Gaul, I.4    Portl, S.5    Philipp, T.6    Heemann, U.W.7
  • 75
    • 84862299279 scopus 로고    scopus 로고
    • Immunosuppression with 4SC-101, a novel inhibitor of dihydroorotate dehydrogenase, in a rat model of renal transplantation
    • Rusai K, Schmaderer C, Baumann M, et al. Immunosuppression with 4SC-101, a novel inhibitor of dihydroorotate dehydrogenase, in a rat model of renal transplantation. Transplantation 2012; 93:1101-1107.
    • (2012) Transplantation , vol.93 , pp. 1101-1107
    • Rusai, K.1    Schmaderer, C.2    Baumann, M.3
  • 76
    • 16244399175 scopus 로고    scopus 로고
    • Inhibition of matrix metalloproteinase during chronic allograft nephropathy in rats
    • DOI 10.1097/01.TP.0000151644.85832.B5
    • Lutz J, Yao Y, Song E, et al. Inhibition of matrix metalloproteinases during chronic allograft nephropathy in rats. Transplantation 2005; 79:655-661. (Pubitemid 40463171)
    • (2005) Transplantation , vol.79 , Issue.6 , pp. 655-661
    • Lutz, J.1    Yao, Y.2    Song, E.3    Antus, B.4    Hamar, P.5    Liu, S.6    Heemann, U.7
  • 77
    • 80054748790 scopus 로고    scopus 로고
    • Imbalance of metalloproteinase/tissue inhibitors of metalloproteinase system in renal transplant recipients with chronic allograft injury
    • Mazanowska O, Kaminska D, Krajewska M, et al. Imbalance of metalloproteinase/tissue inhibitors of metalloproteinase system in renal transplant recipients with chronic allograft injury. Transplantation Proc 2011; 43:3000-3003.
    • (2011) Transplantation Proc , vol.43 , pp. 3000-3003
    • Mazanowska, O.1    Kaminska, D.2    Krajewska, M.3
  • 78
    • 84869750267 scopus 로고    scopus 로고
    • Intraparenchymal injection of bone marrow mesenchymal stem cells reduces kidney fibrosis after ischemiareperfusion in cyclosporine-immunosuppressed rats
    • doi: 10.3727/096368912X640448. [Epub ahead of print]
    • Alfarano C, Roubeix C, Chaaya R, et al. Intraparenchymal injection of bone marrow mesenchymal stem cells reduces kidney fibrosis after ischemiareperfusion in cyclosporine-immunosuppressed rats. Cell Transplant 2012. doi: 10.3727/096368912X640448. [Epub ahead of print]
    • (2012) Cell Transplant
    • Alfarano, C.1    Roubeix, C.2    Chaaya, R.3
  • 80
    • 84863826559 scopus 로고    scopus 로고
    • The impact of mesenchymal stem cell therapy in transplant rejection and tolerance
    • Franquesa M, Hoogduijn MJ, Baan CC. The impact of mesenchymal stem cell therapy in transplant rejection and tolerance. Current Opin Organ Transplant 2012; 17:355-361.
    • (2012) Current Opin Organ Transplant , vol.17 , pp. 355-361
    • Franquesa, M.1    Hoogduijn, M.J.2    Baan, C.C.3
  • 81
    • 84869020769 scopus 로고    scopus 로고
    • Mesenchymal stem cell therapy prevents interstitial fibrosis and tubular atrophy in a rat kidney allograft model
    • [Epub ahead of print]
    • Franquesa M, Herrero E, Torras J, et al. Mesenchymal stem cell therapy prevents interstitial fibrosis and tubular atrophy in a rat kidney allograft model. Stem Cells Dev 2012. [Epub ahead of print]
    • (2012) Stem Cells Dev
    • Franquesa, M.1    Herrero, E.2    Torras, J.3
  • 82
    • 84859811352 scopus 로고    scopus 로고
    • Role of bone marrow cells in the development of pancreatic fibrosis in a rat model of pancreatitis induced by a choline-deficient/ethionine-supplemented diet
    • Akita S, Kubota K, Kobayashi A, et al. Role of bone marrow cells in the development of pancreatic fibrosis in a rat model of pancreatitis induced by a choline-deficient/ethionine-supplemented diet. Biochem Biophys Res Commun 2012; 420:743-749.
    • (2012) Biochem Biophys Res Commun , vol.420 , pp. 743-749
    • Akita, S.1    Kubota, K.2    Kobayashi, A.3
  • 83
    • 84860586403 scopus 로고    scopus 로고
    • Bone marrow transplantation improves hepatic fibrosis in abcb4-/-mice via th1 response and matrix metalloproteinase activity
    • Roderfeld M, Rath T, Pasupuleti S, et al. Bone marrow transplantation improves hepatic fibrosis in Abcb4-/-mice via Th1 response and matrix metalloproteinase activity. Gut 2012; 61:907-916.
    • (2012) Gut , vol.61 , pp. 907-916
    • Roderfeld, M.1    Rath, T.2    Pasupuleti, S.3
  • 84
    • 84859340721 scopus 로고    scopus 로고
    • Inhibition of the p38 MAPK pathway ameliorates renal fibrosis in an NPHP2 mouse model
    • Sugiyama N, Kohno M, Yokoyama T. Inhibition of the p38 MAPK pathway ameliorates renal fibrosis in an NPHP2 mouse model. Nephrol Dial Transplant 2012; 27:1351-1358.
    • (2012) Nephrol Dial Transplant , vol.27 , pp. 1351-1358
    • Sugiyama, N.1    Kohno, M.2    Yokoyama, T.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.