Role of bone marrow cells in the development of pancreatic fibrosis in a rat model of pancreatitis induced by a choline-deficient/ethionine-supplemented diet

Biochemical and Biophysical Research Communications

Volumn 420, Issue 4, 2012, Pages 743-749

  Akita, Shingo ^a   Kubota, Koji ^a   Kobayashi, Akira ^a   Misawa, Ryosuke ^a   Shimizu, Akira ^a   Nakata, Takenari ^a   Yokoyama, Takahide ^a   Takahashi, Masafumi ^b   Miyagawa, Shinichi ^a  

^a SHINSHU UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b JICHI MEDICAL UNIVERSITY   (Japan)

Author keywords

Bone marrow cell; Choline deficient ethionine supplemented diet; Pancreatic fibrosis; Pancreatic stellate cell

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; CHOLINE; DESMIN; ETHIONINE; GREEN FLUORESCENT PROTEIN; PLATELET DERIVED GROWTH FACTOR; TRANSFORMING GROWTH FACTOR;

ACUTE PANCREATITIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BONE MARROW CELL; CHIMERA; CONTROLLED STUDY; CYSTIC FIBROSIS; DIET SUPPLEMENTATION; FEMALE; IMMUNOFLUORESCENCE; IMMUNOHISTOCHEMISTRY; IRRADIATION; NONHUMAN; PANCREATIC STELLATE CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT;

ANIMALS; BONE MARROW CELLS; CHIMERISM; CHOLINE DEFICIENCY; DIETARY SUPPLEMENTS; DISEASE MODELS, ANIMAL; ETHIONINE; FIBROSIS; GREEN FLUORESCENT PROTEINS; MALE; PANCREAS; PANCREATIC STELLATE CELLS; PANCREATITIS; PLATELET-DERIVED GROWTH FACTOR; RATS; RATS, INBRED LEW; TRANSFORMING GROWTH FACTOR BETA;

MUS MUSCULUS; RATTUS;

EID: 84859811352     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2012.03.060     Document Type: Article

References (37)

1. Apte M.V., Haber P.S., Applegate T.L., Norton I.D., McCaughan G.W., Korsten M.A., Pirola R.C., Wilson J.S. Periacinar stellate shaped cells in rat pancreas: identification, isolation, and culture. Gut 1998, 43:128-133.
2. Bachem M.G., Schneider E., Gross H., Weidenbach H., Schmid R.M., Menke A., Siech M., Beger H., Grunert A., Adler G. Identification, culture, and characterization of pancreatic stellate cells in rats and humans. Gastroenterology 1998, 115:421-432.
3. Masamune A., Shimosegawa T. Signal transduction in pancreatic stellate cells. J. Gastroenterol. 2009, 44:249-260.
4. Omary M.B., Lugea A., Lowe A.W., Pandol S.J. The pancreatic stellate cell: a star on the rise in pancreatic diseases. J. Clin. Invest. 2007, 117:50-59.
5. Bachem M.G., Schunemann M., Ramadani M., Siech M., Beger H., Buck A., Zhou S., Schmid-Kotsas A., Adler G. Pancreatic carcinoma cells induce fibrosis by stimulating proliferation and matrix synthesis of stellate cells. Gastroenterology 2005, 128:907-921.
6. Hwang R.F., Moore T., Arumugam T., Ramachandran V., Amos K.D., Rivera A., Ji B., Evans D.B., Logsdon C.D. Cancer-associated stromal fibroblasts promote pancreatic tumor progression. Cancer Res. 2008, 68:918-926.
7. Vonlaufen A., Joshi S., Qu C., Phillips P.A., Xu Z., Parker N.R., Toi C.S., Pirola R.C., Wilson J.S., Goldstein D., Apte M.V. Pancreatic stellate cells: partners in crime with pancreatic cancer cells. Cancer Res. 2008, 68:2085-2093.
8. Shek F.W., Benyon R.C., Walker F.M., McCrudden P.R., Pender S.L., Williams E.J., Johnson P.A., Johnson C.D., Bateman A.C., Fine D.R., Iredale J.P. Expression of transforming growth factor-beta 1 by pancreatic stellate cells and its implications for matrix secretion and turnover in chronic pancreatitis. Am. J. Pathol. 2002, 160:1787-1798.
9. Phillips P.A., Wu M.J., Kumar R.K., Doherty E., McCarroll J.A., Park S., Pirola R.C., Wilson J.S., Apte M.V. Cell migration: a novel aspect of pancreatic stellate cell biology. Gut 2003, 52:677-682.
10. Ohnishi N., Miyata T., Ohnishi H., Yasuda H., Tamada K., Ueda N., Mashima H., Sugano K. Activin A is an autocrine activator of rat pancreatic stellate cells: potential therapeutic role of follistatin for pancreatic fibrosis. Gut 2003, 52:1487-1493.
11. Phillips P.A., McCarroll J.A., Park S., Wu M.J., Pirola R., Korsten M., Wilson J.S., Apte M.V. Rat pancreatic stellate cells secrete matrix metalloproteinases: implications for extracellular matrix turnover. Gut 2003, 52:275-282.
12. Luttenberger T., Schmid-Kotsas A., Menke A., Siech M., Beger H., Adler G., Grunert A., Bachem M.G. Platelet-derived growth factors stimulate proliferation and extracellular matrix synthesis of pancreatic stellate cells: implications in pathogenesis of pancreas fibrosis. Lab. Invest. 2000, 80:47-55.
13. Schneider E., Schmid-Kotsas A., Zhao J., Weidenbach H., Schmid R.M., Menke A., Adler G., Waltenberger J., Grunert A., Bachem M.G. Identification of mediators stimulating proliferation and matrix synthesis of rat pancreatic stellate cells. Am. J. Physiol. Cell. Physiol. 2001, 281:C532-C543.
14. Mews P., Phillips P., Fahmy R., Korsten M., Pirola R., Wilson J., Apte M. Pancreatic stellate cells respond to inflammatory cytokines: potential role in chronic pancreatitis. Gut 2002, 50:535-541.
15. Hama K., Ohnishi H., Aoki H., Kita H., Yamamoto H., Osawa H., Sato K., Tamada K., Mashima H., Yasuda H., Sugano K. Angiotensin II promotes the proliferation of activated pancreatic stellate cells by Smad7 induction through a protein kinase C pathway. Biochem. Biophys. Res. Commun. 2006, 340:742-750.
16. Baba S., Fujii H., Hirose T., Yasuchika K., Azuma H., Hoppo T., Naito M., Machimoto T., Ikai I. Commitment of bone marrow cells to hepatic stellate cells in mouse. J. Hepatol. 2004, 40:255-260.
17. Kisseleva T., Uchinami H., Feirt N., Quintana-Bustamante O., Segovia J.C., Schwabe R.F., Brenner D.A. Bone marrow-derived fibrocytes participate in pathogenesis of liver fibrosis. J. Hepatol. 2006, 45:429-438.
18. Russo F.P., Alison M.R., Bigger B.W., Amofah E., Florou A., Amin F., Bou-Gharios G., Jeffery R., Iredale J.P., Forbes S.J. The bone marrow functionally contributes to liver fibrosis. Gastroenterology 2006, 130:1807-1821.
19. Chu P.Y., Mariani J., Finch S., McMullen J.R., Sadoshima J., Marshall T., Kaye D.M. Bone marrow-derived cells contribute to fibrosis in the chronically failing heart. Am. J. Pathol. 2010, 176:1735-1742.
20. Haudek S.B., Xia Y., Huebener P., Lee J.M., Carlson S., Crawford J.R., Pilling D., Gomer R.H., Trial J., Frangogiannis N.G., Entman M.L. Bone marrow-derived fibroblast precursors mediate ischemic cardiomyopathy in mice. Proc. Natl. Acad. Sci. USA 2006, 103:18284-18289.
21. Yamaguchi Y., Kubo T., Murakami T., Takahashi M., Hakamata Y., Kobayashi E., Yoshida S., Hosokawa K., Yoshikawa K., Itami S. Bone marrow cells differentiate into wound myofibroblasts and accelerate the healing of wounds with exposed bones when combined with an occlusive dressing. Br. J. Dermatol. 2005, 152:616-622.
22. Li J., Deane J.A., Campanale N.V., Bertram J.F., Ricardo S.D. The contribution of bone marrow-derived cells to the development of renal interstitial fibrosis. Stem Cells 2007, 25:697-706.
23. Hashimoto N., Jin H., Liu T., Chensue S.W., Phan S.H. Bone marrow-derived progenitor cells in pulmonary fibrosis. J. Clin. Invest. 2004, 113:243-252.
24. Ishii G., Sangai T., Sugiyama K., Ito T., Hasebe T., Endoh Y., Magae J., Ochiai A. In vivo characterization of bone marrow-derived fibroblasts recruited into fibrotic lesions. Stem Cells 2005, 23:699-706.
25. Marrache F., Pendyala S., Bhagat G., Betz K.S., Song Z., Wang T.C. Role of bone marrow-derived cells in experimental chronic pancreatitis. Gut 2008, 57:1113-1120.
26. Hakamata Y., Tahara K., Uchida H., Sakuma Y., Nakamura M., Kume A., Murakami T., Takahashi M., Takahashi R., Hirabayashi M., Ueda M., Miyoshi I., Kasai N., Kobayashi E. Green fluorescent protein-transgenic rat: a tool for organ transplantation research. Biochem. Biophys. Res. Commun. 2001, 286:779-785.
27. Inoue H., Ohsawa I., Murakami T., Kimura A., Hakamata Y., Sato Y., Kaneko T., Takahashi M., Okada T., Ozawa K., Francis J., Leone P., Kobayashi E. Development of new inbred transgenic strains of rats with LacZ or GFP. Biochem. Biophys. Res. Commun. 2005, 329:288-295.
28. Kubota K., Soeda J., Misawa R., Mihara M., Miwa S., Ise H., Takahashi M., Miyagawa S. Bone marrow-derived cells fuse with hepatic oval cells but are not involved in hepatic tumorigenesis in the choline-deficient ethionine-supplemented diet rat model. Carcinogenesis 2008, 29:448-454.
29. Haber P.S., Keogh G.W., Apte M.V., Moran C.S., Stewart N.L., Crawford D.H., Pirola R.C., McCaughan G.W., Ramm G.A., Wilson J.S. Activation of pancreatic stellate cells in human and experimental pancreatic fibrosis. Am. J. Pathol. 1999, 155:1087-1095.
30. Casini A., Galli A., Pignalosa P., Frulloni L., Grappone C., Milani S., Pederzoli P., Cavallini G., Surrenti C. Collagen type I synthesized by pancreatic periacinar stellate cells (PSC) co-localizes with lipid peroxidation-derived aldehydes in chronic alcoholic pancreatitis. J. Pathol. 2000, 192:81-89.
31. Banerjee A.K., Galloway S.W., Kingsnorth A.N. Experimental models of acute pancreatitis. Br. J. Surg. 1994, 81:1096-1103.
32. Lankisch P.G., Pohl U., Goke B., Otto J., Wereszczynska-Siemiatkowska U., Grone H.J., Rahlf G. Effect of FOY-305 (camostate) on severe acute pancreatitis in two experimental animal models. Gastroenterology 1989, 96:193-199.
33. Manso M.A., Rebollo A., Pescador R., de Dios I. Action of CCK on CDE diet-induced acute pancreatitis in rats treated with hydrocortisone. Comp. Biochem. Physiol. C Pharmacol. Toxicol. Endocrinol. 1995, 111:257-263.
34. Ida S., Ohmuraya M., Hirota M., Ozaki N., Hiramatsu S., Uehara H., Takamori H., Araki K., Baba H., Yamamura K. Chronic pancreatitis in mice by treatment with choline-deficient ethionine-supplemented diet. Exp. Anim. 2010, 59:421-429.
35. Watanabe T., Masamune A., Kikuta K., Hirota M., Kume K., Satoh K., Shimosegawa T. Bone marrow contributes to the population of pancreatic stellate cells in mice. Am. J. Physiol. Gastrointest. Liver. Physiol. 2009, 297:G1138-G1146.
36. Sparmann G., Kruse M.L., Hofmeister-Mielke N., Koczan D., Jaster R., Liebe S., Wolff D., Emmrich J. Bone marrow-derived pancreatic stellate cells in rats. Cell Res. 2010, 20:288-298.
37. Scarlett C.J., Colvin E.K., Pinese M., Chang D.K., Morey A.L., Musgrove E.A., Pajic M., Apte M., Henshall S.M., Sutherland R.L., Kench J.G., Biankin A.V. Recruitment and activation of pancreatic stellate cells from the bone marrow in pancreatic cancer: a model of tumor-host interaction. PLoS One 2011, 6:e26088.