Moderate effects of apple juice consumption on obesity-related markers in obese men: Impact of diet-gene interaction on body fat content

European Journal of Nutrition

Volumn 51, Issue 7, 2012, Pages 841-850

  Barth, Stephan W ^a   Koch, Tatiana C L ^a   Watzl, Bernhard ^a   Dietrich, Helmut ^b   Will, Frank ^b   Bub, Achim ^a  

^a FEDERAL RESEARCH INSTITUTE OF NUTRITION AND FOOD   (Germany)

^b Forschungsanstalt Geisenheim   (Germany)

Author keywords

Adipokines; Cytokines; Human intervention study; Inflammation; Polyphenols

Indexed keywords

ADIPOCYTOKINE; CYTOKINE; LIPID; POLYPHENOL;

ADULT; AGED; ANTHROPOMETRY; APPLE JUICE; ARTICLE; BODY FAT; BODY MASS; CONTROLLED STUDY; DIET GENE INTERACTION; FABP2 GENE; GENE INTERACTION; GENETIC VARIABILITY; GENOTYPE; HUMAN; HUMAN CELL; INSIG2 GENE; INTERLEUKIN 6 GENE; LIPID BLOOD LEVEL; MAJOR CLINICAL STUDY; MALE; OBESITY; PARALLEL DESIGN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA GENE; PGC1 GENE; PROTEIN BLOOD LEVEL; RANDOMIZED CONTROLLED TRIAL; SINGLE BLIND PROCEDURE; SINGLE NUCLEOTIDE POLYMORPHISM; UCP3 GENE; WAIST CIRCUMFERENCE;

ADIPOKINES; ADIPOSE TISSUE; ADULT; AGED; ALLELES; BEVERAGES; BODY COMPOSITION; BODY MASS INDEX; DIET; FATTY ACID-BINDING PROTEINS; GENE-ENVIRONMENT INTERACTION; GENETIC MARKERS; GENOTYPE; HUMANS; INTERLEUKIN-6; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; ION CHANNELS; LIPIDS; MALE; MALUS; MEMBRANE PROTEINS; MIDDLE AGED; MITOCHONDRIAL PROTEINS; OBESITY; POLYMORPHISM, SINGLE NUCLEOTIDE; PPAR GAMMA; SEQUENCE ANALYSIS, DNA; WAIST CIRCUMFERENCE; YOUNG ADULT;

MALUS X DOMESTICA;

EID: 84870243346     PISSN: 14366207     EISSN: 14366215     Source Type: Journal    
DOI: 10.1007/s00394-011-0264-6     Document Type: Article

References (57)

1. Berghofer A, Pischon T, Reinhold T, Apovian CM, Sharma AM, Willich SN (2008) Obesity prevalence from a European perspective: a systematic review. BMC Public Health 8:200
2. Kopelman PG (2000) Obesity as a medical problem. Nature 404:635-643 (Pubitemid 30205068)
3. Rolls BJ, Ello-Martin JA, Tohill BC (2004) What can intervention studies tell us about the relationship between fruit and vegetable consumption and weight management? Nutr Rev 62:1-17 (Pubitemid 38199349)
4. Prentice AM, Jebb SA (2003) Fast foods, energy density and obesity: a possible mechanistic link. Obes Rev 4:187-194 (Pubitemid 37444213)
5. Hsu CL, Yen GC (2008) Phenolic compounds: evidence for inhibitory effects against obesity and their underlying molecular signaling mechanisms. Mol Nutr Food Res 52:53-61
6. Pinent M, Blade C, Salvado MJ, Blay M, Pujadas G, Fernandez- Larrea J, Arola L, Ardevol A (2006) Procyanidin effects on adipocyte- related pathologies. Crit Rev Food Sci Nutr 46:543-550 (Pubitemid 44371365)
7. Tsuda T (2008) Regulation of adipocyte function by anthocyanins; possibility of preventing the metabolic syndrome. J Agric Food Chem 56:642-646 (Pubitemid 351300225)
8. Knekt P, Kumpulainen J, Jarvinen R, Rissanen H, Heliovaara M, Reunanen A, Hakulinen T, Aromaa A (2002) Flavonoid intake and risk of chronic diseases. Am J Clin Nutr 76:560-568 (Pubitemid 34920833)
9. Vinson JA, Su X, Zubik L, Bose P (2001) Phenol antioxidant quantity and quality in foods: fruits. J Agric Food Chem 49:5315-5321 (Pubitemid 33089671)
10. Aprikian O, Busserolles J, Manach C, Mazur A, Morand C, Davicco MJ, Besson C, Rayssiguier Y, Remesy C, Demigne C (2002) Lyophilized apple counteracts the development of hypercholesterolemia, oxidative stress, and renal dysfunction in obese Zucker rats. J Nutr 132:1969-1976 (Pubitemid 34742886)
11. Osada K, Suzuki T, Kawakami Y, Senda M, Kasai A, Sami M, Ohta Y, Kanda T, Ikeda M (2006) Dose-dependent hypocholesterolemic actions of dietary apple polyphenol in rats fed cholesterol. Lipids 41:133-139
12. Ohta Y, Sami M, Kanda T, Saito K, Osada K, Kato H (2006) Gene expression analysis of the anti-obesity effect by apple polyphenols in rats fed a high fat diet or a normal diet. J Oleo Sci 55:305-314
13. Osada K, Funayama M, Fuchi S, Sami M, Ohta Y, Kanda T, Ikeda M (2006) Effects of dietary procyanidins and tea polyphenols on adipose tissue mass and fatty acid metabolism in rats on a high fat diet. J Oleo Sci 55:79-89
14. Nagasako-Akazome Y, Kanda T, Ohtake Y, Shimasaki H, Kobayashi T (2007) Apple polyphenols influence cholesterol metabolism in healthy subjects with relatively high body mass index. J Oleo Sci 56:417-428
15. deOliveira MC, Sichieri R, Venturim MR (2008) A low-energydense diet adding fruit reduces weight and energy intake in women. Appetite 51:291-295
16. Song Y, Manson JE, Buring JE, Sesso HD, Liu S (2005) Associations of dietary flavonoids with risk of type 2 diabetes, and markers of insulin resistance and systemic inflammation in women: a prospective study and cross-sectional analysis. J Am Col Nutr 24:376-384 (Pubitemid 41339204)
17. Scalbert A, Manach C, Morand C, Remesy C, Jimenez L (2005) Dietary polyphenols and the prevention of disease. Crit Rev Food Sci Nutr 45:287-306
18. Koch TC, Briviba K, Watzl B, Fähndrich C, Bub A, Rechkemmer G, Barth SW (2009) Prevention of colon carcinogenesis by apple juice in vivo: impact of juice constituents and obesity. Mol Nutr Food Res 53:1289-1302
19. Matsui N, Ito R, Nishimura E, Yoshikawa M, Kato M, Kamei M, Shibata H, Matsumoto I, Abe K, Hashizume S (2005) Ingested cocoa can prevent high-fat diet-induced obesity by regulating the expression of genes for fatty acid metabolism. Nutrition 21:594-601 (Pubitemid 40585860)
20. Terra X, Montagut G, Bustos M, Llopiz N, Ardevol A, Blade C, Fernandez-Larrea J, Pujadas G, Salvado J, Arola L, Blay M (2009) Grape-seed procyanidins prevent low-grade inflammation by modulating cytokine expression in rats fed a high-fat diet. J Nutr Biochem 20:210-218
21. Hofker M, Wijmenga C (2009) A supersized list of obesity genes. Nat Genet 41:139-140
22. Rankinen T, Zuberti A, Chagnon YC, Weisnagel SJ, Argyropoulos G, Walts B (2006) The human obesity gene map: the 2005 update. Obesity 14:529-644 (Pubitemid 46219737)
23. Barth SW, Fahndrich C, Bub A, Dietrich H, Watzl B, Will F, Briviba K, Rechkemmer G (2005) Cloudy apple juice decreases DNA damage, hyperproliferation and aberrant crypt foci development in the distal colon of DMH-initiated rats. Carcinogenesis 26:1414-1421 (Pubitemid 41417884)
24. Newton CR, Graham A, Heptinstall LE, Powell SJ, Summers C, Kalsheker N, Smith JC, Markham AF (1989) Analysis of any point mutation in DNA. The amplification refractory mutation system (ARMS). Nucleic Acids Res 17:2503-2516
25. Okayama H, Curiel DT, Brantly ML, Holmes MD, Crystal RG (1989) Rapid, nonradioactive detection of mutations in the human genome by allele-specific amplification. J Lab Clin Med 114:105-113 (Pubitemid 19212768)
26. Nazarenko IA, Bhatnagar SK, Hohman RJ (1997) A closed tube format for amplification and detection of DNA based on energy transfer. Nucleic Acids Res 25:2516-2521 (Pubitemid 27303715)
27. Nakazato K, Song H, Waga T (2006) Effects of dietary apple polyphenol on adipose tissues weights in Wistar rats. Exp Anim 55:383-389 (Pubitemid 44203324)
28. Akazome Y, Kametani N, Kanda T, Shimasaki H, Kobayashi S (2010) Evaluation of safety of excessive intake and efficacy of long-term intake of beverages containing apple polyphenols. J Oleo Sci 59:321-333
29. Moreno-Aliaga MJ, Santos JL, Marti A, Martinez JA (2005) Does weight loss prognosis depend on genetic make-up? Obes Rev 6:155-168 (Pubitemid 40604424)
30. Wernstedt I, Eriksson AL, Berndtsson A, Hoffstedt J, Skrtic S, Hedner T, Hultén LM, Wiklund O, Ohlsson C, Jansson JO (2004) A common polymorphism in the interleukin-6 gene promoter is associated with overweight. Int J Obes Relat Metab Disord 28:1272-1279 (Pubitemid 39389584)
31. Strandberg L, Mellström D, Ljunggren O, Grundberg E, Karlsson MK, Holmberg AH, Orwoll ES, Eriksson AL, Svedberg J, Bengtsson M, Ohlsson C, Jansson JO (2008) IL6 and IL1B polymorphisms are associated with fat mass in older men: the MrOS Study Sweden. Obesity 16:710-713 (Pubitemid 351328025)
32. Humphries SE, Luong LA, Ogg MS, Hawe E, Miller GJ (2001) The interleukin-6-174 G/C promoter polymorphism is associated with risk of coronary heart disease and systolic blood pressure in healthy men. Eur Heart J 22:2243-2252 (Pubitemid 34000979)
33. Herbert A, Liu C, Karamohamed S, Liu J, Manning A, Fox CS, Meigs JB, Cupples LA (2006) BMI modifies associations of IL-6 genotypes with insulin resistance: the Framingham Study. Obesity 14:1454-1461 (Pubitemid 46219672)
34. Goyenechea E, Parra D, Martínez JA (2007) Impact of interleukin 6-174G>C polymorphism on obesity-related metabolic disorders in people with excess in body weight. Metabolism 56:1643-1648 (Pubitemid 350060931)
35. Bobe G, Murphy G, Albert PS, Sansbury LB, Young MR, Lanza E, Schatzkin A, Colburn NH, Cross AJ (2011) Do interleukin polymorphisms play a role in the prevention of colorectal adenoma recurrence by dietary flavonols? Eur J Cancer Prev 20:86-95
36. Marotta F, Koike K, Lorenzetti A, Naito Y, Fayet F, Shimizu H, Marandola P (2007) Nutraceutical strategy in aging: targeting heat shock protein and inflammatory profile through understanding interleukin-6 polymorphism. Ann NY Acad Sci 1119:196-202 (Pubitemid 350191229)
37. Ukkola O, Tremblay A, Sun G, Chagnon YC, Bouchard C (2001) Genetic variation at the uncoupling protein 1, 2 and 3 loci and the response to long-term overfeeding. Eur J Clin Nutr 55:1008-1015 (Pubitemid 33040099)
38. Yoon Y, Park BL, Cha MN, Kim KS, Cheong HS, Choi YH, Shin HD (2007) Effects of genetic polymorphisms of UCP2 and UCP3 on very low calorie diet-induced body fat reduction in Korean female subjects. Biochem Biophys Res Commun 359:451-456 (Pubitemid 46908798)
39. Ricciardi R, Talbot LA (2007) Use of bioelectrical impedance analysis in the evaluation, treatment, and prevention of overweight and obesity. J Am Acad Nurse Pract 19:235-241
40. Sugiyama H, Akazome Y, Shoji T, Yamaguchi A, Yasue M, Kanda T, Ohtake Y (2007) Oligomeric procyanidins in apple polyphenol are main active components for inhibition of pancreatic lipase and triglyceride absorption. J Agric Food Chem 55:4604-4609 (Pubitemid 46932661)
41. de la Garza AL, Milagro FI, Boque N, Campión J, Martínez JA (2011) Natural inhibitors of pancreatic lipase as new players in obesity treatment. Planta Med 77:773-785
42. Pinent M, Blade MC, Salvado MJ, Arola L, Ardevol A (2005) Intracellular mediators of procyanidin-induced lipolysis in 3T3- L1 adipocytes. J Agric Food Chem 53:262-266 (Pubitemid 40129913)
43. Vogels N, Nijs IM, Westerterp-Plantenga MS (2004) The effect of grape-seed extract on 24 h energy intake in humans. Eur J Clin Nutr 58:667-673 (Pubitemid 38500138)
44. Ardevol A, Blade C, Salvado MJ, Arola L (2000) Changes in lipolysis and hormone-sensitive lipase expression caused by procyanidins in 3T3-L1 adipocytes. Int J Obes Relat Metab Disord 24:319-324 (Pubitemid 30137722)
45. Hsu CL, Yen GC (2007) Effects of flavonoids and phenolic acids on the inhibition of adipogenesis in 3T3-L1 adipocytes. J Agric Food Chem 55:8404-8410
46. Pinent M, Blade MC, Salvado MJ, Arola L, Hackl H, Quackenbush J, Trajanoski Z, Ardevol A (2005) Grape-seed derived procyanidins interfere with adipogenesis of 3T3-L1 cells at the onset of differentiation. Int J Obes 29:934-941 (Pubitemid 41076233)
47. Fruhbeck G, Jebb SA, Prentice AM (1998) Leptin: physiology and pathophysiology. Clin Physiol 18:399-419 (Pubitemid 28451466)
48. Steppan CM, Bailey ST, Bhat S, Brown EJ, Banerjee RR, Wright CM, Patel HR, Ahima RS, Lazar MA (2001) The hormone resistin links obesity to diabetes. Nature 409:307-312 (Pubitemid 32151228)
49. Xu A, Wang Y, Xu JY, Stejskal D, Tam S, Zhang J, Wat NM, Wong WK, Lam KS (2006) Adipocyte fatty acid-binding protein is a plasma biomarker closely associated with obesity and metabolic syndrome. Clin Chem 52:405-413
50. Yang Q, Graham TE, Mody N, Preitner F, Peroni OD, Zabolotny JM, Kotani K, Quadro L, Kahn BB (2005) Serum retinol binding protein 4 contributes to insulin resistance in obesity and type 2 diabetes. Nature 436:356-362 (Pubitemid 41065039)
51. Lumeng CN, Saltiel AR (2011) Inflammatory links between obesity and metabolic disease. J Clin Invest 121:2111-2117
52. Tilg H, Moschen AR (2006) Adipocytokines: mediators linking adipose tissue, inflammation and immunity. Nat Rev Immunol 6:772-783 (Pubitemid 44453463)
53. Bantle JP, Raatz SK, Thomas W, Georgopoulos A (2000) Effects of dietary fructose on plasma lipids in healthy subjects. Am J Clin Nutr 72:1128-1134
54. Parks EJ, Hellerstein MK (2000) Carbohydrate-induced hypertriacylglycerolemia: historical perspective and review of biological mechanisms. Am J Clin Nutr 71:412-433 (Pubitemid 30061218)
55. Miller M, Stone NJ, Ballantyne C et al (2011) Triglycerides and cardiovascular disease: a scientific statement from the American Heart Association. Circulation 123:2292-2333
56. Singleton VL, Rossi JA (1965) Colorimetry of total phenolics with phosphomolybdic-phosphotungstic acid reagents. Am J Enol Vitic 16:144-158
57. Oki K, Yamane K, Kamei N, Asao T, Awaya T, Kohno N (2009) The single nucleotide polymorphism upstream of insulin-induced gene 2 (INSIG2) is associated with the prevalence of hypercholesterolaemia, but not with obesity, in Japanese American women. Br J Nutr 101:322-327