Self-amplification mechanisms of mast cell activation: A new look in allergy

Current Molecular Medicine

Volumn 12, Issue 10, 2012, Pages 1329-1339

  He, S ^a   Zhang, H ^b   Zeng, X ^a   Yang, P ^c  

^a THE FIRST AFFILIATED HOSPITAL OF NANJING MEDICAL UNIVERSITY   (China)

^b HAINAN MEDICAL UNIVERSITY   (China)

^c MCMASTER UNIVERSITY   (Canada)

Author keywords

Allergen; Cytokine; Degranulation; Effector cells; IgG; Self amplification

Indexed keywords

ADENOSINE RECEPTOR; ANAPHYLATOXIN; CD64 ANTIGEN; COMPLEMENT COMPONENT C3A; COMPLEMENT COMPONENT C5A; CONTRAST MEDIUM; CYTOKINE RECEPTOR; FC RECEPTOR; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; HISTAMINE; IMMUNOGLOBULIN E; IMMUNOGLOBULIN G; INTERFERON; INTERLEUKIN 10; INTERLEUKIN 12; INTERLEUKIN 13; INTERLEUKIN 1BETA; INTERLEUKIN 3; INTERLEUKIN 4; INTERLEUKIN 6; MYELOID DIFFERENTIATION FACTOR 88; NEUROKININ 1 RECEPTOR; PROTEINASE ACTIVATED RECEPTOR; PROTEINASE ACTIVATED RECEPTOR 2; TOLL LIKE RECEPTOR; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 3; TOLL LIKE RECEPTOR 4; TUMOR NECROSIS FACTOR; UNINDEXED DRUG;

ALLERGY; ARTICLE; BASOPHIL; BASOPHIL DEGRANULATION; CELL ACTIVATION; CELL MIGRATION; CHEMOTAXIS; CYTOKINE PRODUCTION; EFFECTOR CELL; EXOCYTOSIS; HUMAN; IMMUNOFLUORESCENCE TEST; IMMUNOREACTIVITY; INFLAMMATION; MAST CELL; MAST CELL DEGRANULATION; NONHUMAN; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION;

ALLERGENS; ANTIGEN PRESENTATION; BASOPHILS; HUMANS; HYPERSENSITIVITY; IMMUNOGLOBULIN E; IMMUNOGLOBULIN G; INFLAMMATION; LYSOPHOSPHOLIPIDS; MAST CELLS; SPHINGOSINE;

EID: 84870215419     PISSN: 15665240     EISSN: 18755666     Source Type: Journal    
DOI: 10.2174/156652412803833544     Document Type: Article

References (101)

1. Warner JO, Kaliner MA, Crisci CD, et al. World Allergy Organization Specialty and Training Council. Allergy practice worldwide: a report by the World Allergy Organization Specialty and Training Council. Int Arch Allergy Immunol 2006; 139: 166-174.
2. Barnes PJ. Pathophysiology of allergic inflammation. Immunol Rev 2011; 242: 31-50.
3. Sanchez-Miranda E, Ibarra-Sanchez A, Gonzalez-Espinosa C. Fyn kinase controls FcepsilonRI receptor-operated calcium entry necessary for full degranulation in mast cells. Biochem Biophys Res Commun 2010; 391: 1714-1720.
4. Marone G, Triggiani M, Genovese A, De Paulis A. Role of human mast cells and basophils in bronchial asthma. Adv Immunol 2005; 88: 97-160.
5. Vliagoftis H, Befus AD. Rapidly changing perspectives about mast cells at mucosal surfaces. Immunol Rev 2005; 206: 190-203.
6. Kalesnikoff J, Galli SJ. Anaphylaxis: mechanisms of mast cell activation. Chem Immunol Allergy 2010; 95: 45-66.
7. Pettipher R, Hansel TT, Armer R. Antagonism of the prostaglandin D2 receptors DP1 and CRTH2 as an approach to treat allergic diseases. Nat Rev Drug Discov 2007; 6: 313-325.
8. Blank U, Rivera J. In: Current Protocols in Cell Biology; Juan S. Bonifacino, Mary Dasso, Joe B. Harford, Jennifer Lippincott-Schwartz, Kenneth M. Yamada, Eds. John Wiley & Sons. 2006; Chapter 15: Unit 15.1.1.
9. Vliagoftis H, Befus AD. Mast cells at mucosal frontiers. Curr Mol Med 2005; 5: 573-589.
10. Wang M, Takeda K, Shiraishi Y, et al. Peanut-induced intestinal allergy is mediated through a mast cell-IgEFcepsilonRI-IL-13 pathway. J Allergy Clin Immunol 2010; 126: 306-316.
11. Sada K, Yamamura H. Protein-tyrosine kinases and adaptor proteins in FcepsilonRI-mediated signaling in mast cells. Curr Mol Med 2003; 3: 85-894.
12. Holowka D, Sil D, Torigoe C, Baird B. Insights into immunoglobulin E receptor signaling from structurally defined ligands. Immunol Rev 2007; 217: 269-279.
13. Soundararajan S, Kikuchi Y, Joseph K, Kaplan AP. Functional assessment of pathogenic IgG subclasses in chronic autoimmune urticaria. J Allergy Clin Immunol 2005; 115: 815-821.
14. Woolhiser MR, Brockow K, Metcalfe DD. Activation of human mast cells by aggregated IgG through FcgammaRI: additive effects of C3a. Clin Immunol 2004; 110: 172-180.
15. Karlberg M, Xiang Z, Nilsson G. Fc gamma RI-mediated activation of human mast cells promotes survival and induction of the pro-survival gene Bfl-1. J Clin Immunol 2008; 28: 250-255.
16. Ujike A, Ishikawa Y, Ono M, et al. Modulation of immunoglobulin (Ig)E-mediated systemic anaphylaxis by lowaffinity Fc receptors for IgG. J Exp Med 1999; 189: 1573-1579.
17. Chong HJ, Andrew Bouton L, Bailey DP, et al. IL-4 selectively enhances FcgammaRIII expression and signaling on mouse mast cells. Cell Immunol 2003; 224: 65-73.
18. Abboud G, Staumont-Sallé D, Kanda A, et al. Fc(epsilon)RI and FcgammaRIII/CD16 differentially regulate atopic dermatitis in mice. J Immunol 2009; 182: 6517-6526.
19. Khodoun M, Strait R, Orekov T, et al. Peanuts can contribute to anaphylactic shock by activating complement. J Allergy Clin Immunol 2009; 123: 342-351.
20. Szebeni J. Complement activation-related pseudoallergy caused by liposomes, micellar carriers of intravenous drugs, and radiocontrast agents. Crit Rev Ther Drug Carrier Syst 2001; 18: 567-606.
21. Heimbach L, Li Z, Berkowitz P, et al. The C5a receptor on mast cells is critical for the autoimmune skin-blistering disease bullous pemphigoid. J Biol Chem 2011; 286: 15003-15009.
22. Moormann C, Artuc M, Pohl E, et al. Functional characterization and expression analysis of the proteinaseactivated receptor-2 in human cutaneous mast cells. J Invest Dermatol 2006; 126: 746-755.
23. He S, Xie H, Fu YL. Activation of human tonsil and skin mast cells by agonists of proteinase activated receptor-2. Acta Pharmacol Sin 2005; 26: 568-574.
24. He S, Zhang Z, Zhang H, et al. Analysis of properties and proinflammatory functions of cockroach allergens Per a 1.01s. Scand J Immunol 2011; 74: 288-295.
25. Christerson U, Keita AV, Söderholm JD, Gustafson-Svärd C. Increased expression of protease-activated receptor-2 in mucosal mast cells in Crohn's ileitis. J Crohns Colitis 2009; 3: 100-108.
26. Brzezińska-Błaszczyk E, Wierzbicki M. Mast cell Toll-like receptors (TLRs). Postepy. Hig Med Dosw (Online) 2010; 64: 11-21.
27. McCurdy JD, Olynych TJ, Maher LH, Marshall JS. Cutting edge: distinct Toll-like receptor 2 activators selectively induce different classes of mediator production from human mast cells. J Immunol 2003; 170: 1625-1629.
28. Mrabet-Dahbi S, Metz M, Dudeck A, Zuberbier T, Maurer M. Murine mast cells secrete a unique profile of cytokines and prostaglandins in response to distinct TLR2 ligands. Exp Dermatol 2009; 18: 437-444.
29. Haidl ID, McAlpine SM, Marshall JS. Enhancement of mast cell IL-6 production by combined toll-like and nucleotidebinding oligomerization domain-like receptor activation. Int Arch Allergy Immunol 2011; 154: 227-235.
30. Kulka M, Alexopoulou L, Flavell RA, Metcalfe DD. Activation of mast cells by double-stranded RNA: evidence for activation through Toll-like receptor 3. J Allergy Clin Immunol 2004; 114: 174-182.
31. Hochdörfer T, Kuhny M, Zorn CN, et al. Activation of the PI3K pathway increases TLR-induced TNF-β and IL-6 but reduces IL-1 β production in mast cells. Cell Signal 2011; 23: 866-875.
32. Takenaka H, Ushio H, Niyonsaba F, et al. Synergistic augmentation of inflammatory cytokine productions from murine mast cells by monomeric IgE and toll-like receptor ligands. Biochem Biophys Res Commun 2010; 391: 471-476.
33. Selander C, Engblom C, Nilsson G, Scheynius A, Andersson CL. TLR2/MyD88-dependent and -independent activation of mast cell IgE responses by the skin commensal yeast Malassezia sympodialis. J Immunol 2009; 182: 4208-4216.
34. Kambayashi T, Larosa DF, Silverman MA, Koretzky GA. Cooperation of adapter molecules in proximal signaling cascades during allergic inflammation. Immunol Rev 2009; 232: 99-114.
35. Buceta M, Domínguez E, Castro M, et al. A new chemical tool (C0036E08) supports the role of adenosine A(2B) receptors in mediating human mast cell activation. Biochem Pharmacol 2008; 76: 912-921.
36. Hua X, Chason KD, Patel JY, Naselsky WC, Tilley SL. IL-4 amplifies the pro-inflammatory effect of adenosine in human mast cells by changing expression levels of adenosine receptors. PLoS One 2011; 6: e24947.
37. Hua X, Chason KD, Fredholm BB, Deshpande DA, Penn RB, Tilley SL. Adenosine induces airway hyperresponsiveness through activation of A3 receptors on mast cells. J Allergy Clin Immunol 2008; 122: 107-113.
38. Drube S, Schmitz F, Göpfert C, Weber F, Kamradt T. C-Kit controls IL-1_-induced effector functions in HMC-cells. Eur J Pharmacol 2012; 675: 57-62.
39. Alam R, Forsythe P, Stafford S, et al. Monocyte chemotactic protein-2, monocyte chemotactic protein-3, and fibroblastinduced cytokine. Three new chemokines induce chemotaxis and activation of basophils. J Immunol 1994; 153: 3155-3159.
40. Yoshimoto T, Nakanishi K. Roles of IL-18 in basophils and mast cells. Allergol Int 2006; 55: 105-113.
41. Hueber AJ, Alves-Filho JC, Asquith DL, et al. IL-33 induces skin inflammation with mast cell and neutrophil activation. Eur J Immunol 2011; 41: 2229-2237.
42. Huang B, Lei Z, Zhang GM, et al. SCF-mediated mast cell infiltration and activation exacerbate the inflammation and immunosuppression in tumor microenvironment. Blood 2008; 112: 1269-1279.
43. Yang H, Wei J, Zhang H, et al. Upregulation of toll-like receptor (TLR) expression and release of cytokines from mast cells by IL-12. Cell Physiol Biochem 2010; 26: 337-346
44. Yang H, Wei J, Zhang H, Lin L, Zhang W, He S. Upregulation of Toll-like receptor (TLR) expression and release of cytokines from P815 mast cells by GM-CSF. BMC Cell Biol 2009; 10: 37.
45. van der Kleij HP, Ma D, Redegeld FA, Kraneveld AD, Nijkamp FP, Bienenstock J. Functional expression of neurokinin 1 receptors on mast cells induced by IL-4 and stem cell factor. J Immunol 2003; 171: 2074-2079.
46. Koon HW, Pothoulakis C. Immunomodulatory properties of substance P: the gastrointestinal system as a model. Ann N Y Acad Sci 2006; 1088: 23-40.
47. Castellani ML, Ciampoli C, Felaco M, et al. Neuropeptide substance P induces mRNA expression and secretion of CXCL8 chemokine, and HDC in human umbilical cord blood mast cells. Clin Invest Med 2008; 31: E362-E372.
48. Karimi K, Kool M, Nijkamp FP, Redegeld FA. Substance P can stimulate prostaglandin D2 and leukotriene C4 generation without granule exocytosis in murine mast cells. Eur J Pharmacol 2004; 489: 49-54.
49. Zhang B, Alysandratos KD, Angelidou A, et al. Human mast cell degranulation and preformed TNF secretion require mitochondrial translocation to exocytosis sites: relevance to atopic dermatitis. J Allergy Clin Immunol 2011; 127: 1522-1531.
50. Tancowny BP, Karpov V, Schleimer RP, Kulka M. Substance P primes lipoteichoic acid- and Pam3CysSerLys4-mediated activation of human mast cells by up-regulating Toll-like receptor 2. Immunology 2010; 131: 220-230.
51. Collaco CR, Hochman DJ, Goldblum RM, Brooks EG. Effect of sodium sulfite on mast cell degranulation and oxidant stress. Ann Allergy Asthma Immunol 2006; 96: 550-556.
52. He S, Xie H, Fu YL. Inhibition of tryptase release from human colon mast cells by histamine receptor antagonists. Asian Pac J Allergy 2005; 23: 35-39.
53. Desai P, Thurmond RL. Histamine H4 receptor activation enhances LPS-induced IL-6 production in mast cells via ERK and PI3K activation. Eur J Immunol 2011; 41: 1764-1773.
54. Devouassoux G, Saxon A, Metcalfe DD, et al. Chemical constituents of diesel exhaust particles induce IL-4 production and histamine release by human basophils. J Allergy Clin Immunol 2002; 109: 847-853.
55. Noviski N, Brewer JP, Skornik WA, Galli SJ, Drazen JM, Martin TR. Mast cell activation is not required for induction of airway hyperresponsiveness by ozone in mice. J Appl Physiol 1999; 86: 202-210.
56. Albrecht M, Müller K, Köhn FM, Meineke V, Mayerhofer A. Ionizing radiation induces degranulation of human mast cells and release of tryptase. Int J Radiat Biol 2007; 83: 535-541.
57. Kempuraj D, Asadi S, Zhang B, et al. Mercury induces inflammatory mediator release from human mast cells. J Neuroinflammation 2010; 7: 20.
58. Gibbs BF, Räthling A, Zillikens D, Huber M, Haas H. Initial Fc epsilon RI-mediated signal strength plays a key role in regulating basophil signaling and deactivation. J Allergy Clin Immunol 2006; 118: 1060-1067.
59. Sheen CH, Schleimer RP, Kulka M. Codeine induces human mast cell chemokine and cytokine production: involvement of G-protein activation. Allergy 2007; 62: 532-538.
60. Wong D, Ogle CW. Chronic parenterally administered nicotine and stress- or ethanol-induced gastric mucosal damage in rats. Eur J Pharmacol 1995; 292: 157-162.
61. He S. Key role of mast cells and their major secretory products in inflammatory bowel disease. World J Gastroenterol 2004; 10: 309-318.
62. He S, Gaça MD, Walls AF. A role for tryptase in the activation of human mast cells: modulation of histamine release by tryptase and inhibitors of tryptase. J Pharmacol Exp Ther 1998; 286: 289-297.
63. Okayama Y, Benyon RC, Lowman MA, Church MK. In vitro effects of H1-antihistamine on PGD2 release from mast cells of human lung, tonsil, and skin. Allergy 1994; 49: 246-253.
64. Law M, Morales JL, Mottram LF, Iyer A, Peterson BR, August A. Structural requirements for the inhibition of calcium mobilization and mast cellactivation by the pyrazole derivative BTP2. Int J Biochem Cell Biol 2011; 43: 1228-1239.
65. Spiegl N, Didichenko S, McCaffery P, Langen H, Dahinden CA. Human basophils activated by mast cell-derived IL-3 express retinaldehyde dehydrogenase-II and produce the immunoregulatory mediator retinoic acid. Blood 2008; 112: 3762-3771.
66. Tschopp CM, Spiegl N, Didichenko S, et al. Granzyme B, a novel mediator of allergic inflammation: its induction and release in blood basophils and human asthma. Blood 2006; 108: 2290-2299.
67. Schroeder JT, Chichester KL, Bieneman AP. Human basophils secrete IL-3: evidence of autocrine priming for phenotypic and functional responses in allergic disease. J Immunol 2009; 182: 2432-2438.
68. Wodnar-Filipowicz A, Heusser CH, Moroni C. Production of the haemopoietic growth factors GM-CSF and interleukin-3 bymast cells in response to IgE receptor-mediated activation. Nature 1989; 339: 150-152.
69. Zhang, H Yang H, Zhang L, et al. Induction of IL-4 Release and Upregulated Expression of Protease Activated Receptors by GM-CSF in P815 Cells. Cytokine 2009; 48: 196-202.
70. Dahl C, Hoffmann HJ, Saito H, Schiøtz PO. Human mast cells express receptors for IL-3, IL-5 and GM-CSF; a partial map of receptors on human mast cells cultured in vitro. Allergy 2004; 59: 1087-1096.
71. Baraniuk JN. Pathogenesis of allergic rhinitis. J Allergy Clin Immunol 1997; 99: S763-S772.
72. Smithgall MD, Comeau MR, Yoon BR, Kaufman D, Armitage R, Smith DE. IL-33 amplifies both Th1- and Th2-type responses through its activity on human basophils, allergenreactive Th2 cells, iNKT and NK cells. Int Immunol 2008; 20: 1019-1030.
73. Boyce JA. Mast cells: beyond IgE. J Allergy Clin Immunol 2003; 111: 24-32.
74. Lorentz A, Wilke M, Sellge G, et al. IL-4-induced priming of human intestinal mast cells for enhanced survival and Th2 cytokine generation is reversible and associated with increased activity of ERK1/2 and c-Fos. J Immunol 2005; 174: 6751-6756.
75. Corry DB, Kheradmand F. Biology and therapeutic potential of the interleukin-4/interleukin-13 signaling pathway in asthma. Am J Respir Med 2002; 1: 185-193.
76. Kaur D, Hollins F, Woodman L, et al. Mast cells express IL-13R alpha 1: IL-13 promotes human lung mast cell proliferation and Fc epsilon RI expression. Allergy 2006; 61: 1047-1053.
77. Kaneko I, Hishinuma T, Suzuki K, et al. Prostaglandin F(2alpha) regulates cytokine responses of mast cells through the receptors for prostaglandin E. Biochem Biophys Res Commun 2008; 367: 590-596.
78. MacGlashan DW Jr. Self-termination/anergic mechanisms in human basophils and mast cells. Int Arch Allergy Immunol 2009; 150: 109-121.
79. Brightling CE, Bradding P, Symon FA, Holgate ST, Wardlaw AJ, Pavord ID. Mast-cell infiltration of airway smooth muscle in asthma. N Engl J Med 2002; 346: 1699-1705.
80. Järvikallio A, Naukkarinen A, Harvima IT, Aalto ML, Horsmanheimo M. Quantitative analysis of tryptase- and chymase-containing mast cells in atopic dermatitis and nummular eczema. Br J Dermatol 1997; 136: 871-877.
81. Hofstra CL, Desai PJ, Thurmond RL, Fung-Leung WP. Histamine H4 receptor mediates chemotaxis and calcium mobilization of mast cells. J Pharmacol Exp Ther 2003; 305: 1212-1221.
82. Nilsson G, Metcalfe DD, Taub DD. Demonstration that platelet-activating factor is capable of activating mast cells and inducing a chemotactic response. Immunology 2000; 99: 314-319.
83. Hart PH. Regulation of the inflammatory response in asthma by mast cell products. Immunol Cell Biol 2001; 79: 149-153.
84. Misiak-Tłoczek A, Brzezińska-Błaszczyk E. IL-6, but not IL-4, stimulates chemokinesis and TNF stimulates chemotaxis of tissue mast cells: involvement of both mitogen-activated protein kinases and phosphatidylinositol 3-kinase signaling pathways. APMIS 2009; 117: 558-567.
85. Brzezi-ska-B-aszczyk E, Pietrzak A, Misiak-T-oczek AH. Tumor necrosis factor (TNF) is a potent rat mast cell chemoattractant. J Interferon Cytokine Res 2007; 27: 911-919.
86. Toru H, Kinashi T, Ra C, Nonoyama S, Yata J, Nakahata T. Interleukin-4 induces homotypic aggregation of human mast cells by promoting LFA-1/ICAM-1 adhesion molecules. Blood 1997; 89: 3296-3302.
87. He S, Zhang H, Chen H, et al. Expression and release of IL-29 by mast cells and modulation of ast cell behavior by IL-29. Allergy 2010; 65: 1234-1241.
88. Olsson N, Taub DD, Nilsson G. Regulation of mast cell migration by T and T cytokines: identification of tumour necrosis factor-alpha and interleukin-4 as mast cell chemotaxins. Scand J Immunol 2004; 59: 267-272.
89. Kambe N, Kambe M, Kochan JP, Schwartz LB. Human skinderived mast cells can proliferate while retaining their characteristic functional and protease phenotypes. Blood 2001; 97: 2045-2052.
90. Kempuraj D, Saito H, Kaneko A, et al. Characterization of mast cell-committed progenitors present in human umbilical cord blood. Blood 1999; 93: 3338-3346.
91. Andersen HB, Holm M, Hetland TE, et al. Comparison of short term in vitro cultured human mast cells from different progenitors - Peripheral blood-derived progenitors generate highly mature and functional mast cells. J Immunol Methods 2008; 336: 166-174.
92. Yamaguchi M, Azuma H, Fujihara M, Hamada H, Ikeda H. Generation of a considerable number of functional mast cells with a high basal level of FcepsilonRI expression from cord blood CD34+ cells by co-culturing them with bone marrow stromal cell line under serum-free conditions. Scand J Immunol 2007; 65: 581-588.
93. Shakoory B, Fitzgerald SM, Lee SA, Chi DS, Krishnaswamy G. The role of human mast cell-derived cytokines in eosinophil biology. J Interferon Cytokine Res 2004; 24: 271-281.
94. Wisniewski JA, Borish L. Novel cytokines and cytokineproducing T cells in allergic disorders. Allergy Asthma Proc 2011; 32: 83-94.
95. Niyonsaba F, Ushio H, Hara M, et al. Antimicrobial peptides human beta-defensins and cathelicidin LL-37 induce the secretion of a pruritogenic cytokine IL-31 by human mast cells. J Immunol 2010; 184: 3526-3534.
96. Bogaert P, Tournoy KG, Naessens T, Grooten J. Where asthma and hypersensitivity pneumonitis meet and differ: noneosinophilic severe asthma. Am J Pathol 2009; 174: 3-13.
97. He S, Peng Q, Walls AF. Potent induction of a neutrophil and eosinophil-rich infiltrate in vivo by human mast cell tryptase: selective enhancement of eosinophil recruitment by histamine. J Immunol 1997; 159: 6216-6225.
98. He S, Walls AF. Human mast cell chymase induces the accumulation of neutrophils, eosinophils and other inflammatory cells in vivo. Brit J Pharmacol 1998; 125: 1491-500.
99. Okada S, Kita H, George TJ, Gleich GJ, Leiferman KM. Migration of eosinophils through basement membrane components in vitro: role of matrix metalloproteinase-9. Am J Respir Cell Mol Biol 1997; 17: 519-528.
100. Dias-Baruffi M, Pereira-da-Silva G, Jamur MC, Roque-Barreira MC. Heparin potentiates in vivo neutrophil migration induced by IL-8. Glycoconj J 1998; 15: 523-526.
101. Thomas PS. Tumour necrosis factor-alpha: the role of this multifunctional cytokine in asthma. Immunol Cell Biol 2001; 79: 132-140.