Fyn kinase controls FcεRI receptor-operated calcium entry necessary for full degranulation in mast cells

Biochemical and Biophysical Research Communications

Volumn 391, Issue 4, 2010, Pages 1714-1720

  Sanchez Miranda, Elizabeth ^a   Ibarra Sanchez, Alfredo ^a   Gonzalez Espinosa, Claudia ^a  

^a DEPARTAMENTO DE FÍSICA   (Mexico)

Author keywords

Allergy; Calcium; Degranulation; Fyn kinase; IgE receptor; IL 2; Mast cells

Indexed keywords

CALCIUM ION; FC EPSILON RECEPTOR I; FC RECEPTOR; GADOLINIUM; IMMUNOGLOBULIN E; IMMUNOGLOBULIN E RECEPTOR; INTERLEUKIN 2; MESSENGER RNA; PROTEIN KINASE FYN; THAPSIGARGIN; TRANSIENT RECEPTOR POTENTIAL CHANNEL 3; TRANSIENT RECEPTOR POTENTIAL CHANNEL 6; TRANSIENT RECEPTOR POTENTIAL CHANNEL 7; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BONE MARROW CELL; CALCIUM MOBILIZATION; CALCIUM TRANSPORT; CELL DIFFERENTIATION; CELLULAR DISTRIBUTION; CONTROLLED STUDY; CROSS LINKING; ENZYME PHOSPHORYLATION; EXTRACELLULAR CALCIUM; IMMUNOPRECIPITATION; IMMUNOSTIMULATION; MAST CELL; MAST CELL DEGRANULATION; MOLECULAR MECHANICS; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION; WILD TYPE;

ANIMALS; BORON COMPOUNDS; CALCIUM; CELL DEGRANULATION; MAST CELLS; MICE; MICE, KNOCKOUT; PROTEIN KINASE C; PROTO-ONCOGENE PROTEINS C-FYN; RECEPTORS, IGE; TRPC CATION CHANNELS;

MUS;

EID: 74849105174     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2009.12.139     Document Type: Article

References (31)

1. Galli S.J., Kalesnikoff J., Grimbaldeston M.A., Piliponsky A.M., Williams C.M., and Tsai M. Mast cells as "tunable" effector and immunoregulatory cells: recent advances. Ann. Rev. Immunol. 23 (2005) 749-786
2. Blank U., and Rivera J. The ins and outs of mast cell exocytosis. Trends Immunol. 25 (2004) 266-273
3. 2+ influx in mast cells. In: Razin E., and Rivera J. (Eds). Signal Transduction in Mast Cells and Basophils (1998), Springer-Verlag, New York, USA 227-246
4. Pribluda V.S., and Metzger H. Evidence for an early rise in inositol 1,4,5-trisphosphate which precedes the rise in other inositol phosphates and in cytoplasmic calcium. J. Biol. Chem. 262 (1987) 11449-11454
5. Putney J.W. A model of receptor-regulated calcium entry. Cell Calcium 7 (1986) 1-12
6. 2+ responses of RBL-2H3 mast cells. Mol. Biol. Cell 6 (1995) 825-839
7. Kraft S., and Kinet J.P. New developments in FcεRI regulation, function and inhibition. Nat. Rev. Immunol. 7 (2007) 365-378
8. Vazquez G., Wedel B.J., Aziz O., Trebak M., and Putney Jr. J.W. The mammalian TRPC cation channels. Biochim. Biophys. Acta 1742 (2004) 21-36
9. Gilfillan A., and Tkaczyk C. Integrated signalling pathways for mast cell-activation. Nat. Rev. Immunol. 6 (2006) 218-230
10. Tolar P., Dráberová L., Tolarová H., and Dráber P. Positive and negative regulation of Fc epsilon receptor I-mediated signaling events by Lyn kinase C-terminal tyrosine phosphorylation. Eur. J. Immunol. 34 (2004) 1136-1145
11. Kawakami Y., Kitaura J., Satterthwaite A.B., Kato R.M., Asai K., Hartman S.E., Maeda-Yamamoto M., Lowell C.A., Rawlings D.J., Witte O.N., and Kawakami T. Redundant and opposing functions of two tyrosine kinases, Btk and Lyn, in mast cell activation. J. Immunol. 165 (2000) 1210-1219
12. Parravicini V., Gadina M., Kovarova M., Odom S., Gonzalez-Espinosa C., Furumoto Y., Saitoh S., Samelson L.W., O'Shea J., and Rivera J. Fyn Kinase initiates complementary signals required for IgE-dependent mast cell degranulation. Nat. Immunol. 3 (2002) 741-748
13. Gomez G., Gonzalez-Espinosa C., Odom S., Baez G., Cid M.E., Ryan J.J., and Rivera J. Impaired FcεRI-dependent gene expression and defective eicosanoid and cytokine production as a consequence of Fyn deficiency in mast cells. J. Immunol. 175 (2005) 7602-7610
14. 2+ indicators with greatly improved fluorescence properties. J. Biol. Chem. 260 (1985) 3440-3450
15. Kunert-Keil C., Bisping F., Krüger J., and Brinkmeier H. Tissue-specific expression of TRP channel genes in the mouse and its variation in three different mouse strains. BMC Genomics 7 (2006) 159-172
16. 3 receptors. J. Physiol. 536 (2001) 3-19
17. 2+ mobilization in FcεRI signaling to degranulation in mast cells. J. Allergy Clin. Immunol. 114 (2004) 1085-1092
18. 4 secretion. J. Biol. Chem. 279 (2004) 29994-29999
19. Trebak M., Vazquez G., Bird G.S., and Putney Jr. J.W. The TRPC 3/6/7 subfamily of cation channels. Cell Calcium 33 (2003) 451-461
20. Lievremont J.P., Bird G.S., and Putney Jr. J.W. Mechanism of inhibition of TRPC cation channels by 2-Aminoethoxydiphenylborane. Mol. Pharmacol. 68 (2005) 758-762
21. 2+, and degranulation in a rat mast cell line. J. Immunol. 180 (2008) 2233-2239
22. Vazquez G., Wedel B.J., Kawasaki B.T., Bird G.S., and Putney Jr. J.W. Obligatory role of Src kinase in the signaling mechanism for TRPC3 cation channels. J. Biol. Chem. 279 (2004) 40521-40528
23. Hisatsune C., Kuroda Y., Nakamura K., Inoue T., Nakamura T., Michikawa T., Mizutani A., and Mikosiba K. Regulation of TRPC6 channel activity by tyrosine phosphorylation. J. Biol. Chem. 279 (2004) 18887-18894
24. 2+ entry channels. Proc. Natl. Acad. Sci. USA 103 (2006) 335-340
25. Chevesich J., Kreuz A.J., and Montell C. Requirement for the PDZ domain protein, INAD, for localization of the TRP store operated channel to a signaling complex. Neuron 18 (1997) 95-105
26. Kurisaki A., Inoue I., Kurisaki K., Yamakawa N., Tsuchida K., and Sugino H. Activin induces long-lasting N-methyl-d-aspartate receptor activation via scaffolding PDZ protein activin receptor interacting protein 1. Neuroscience 151 (2008) 1225-1235
27. Thome M. CARMA1, BCL-10 and MALT-1 in lymphocyte development and activation. Nat. Rev. Immunol. 4 (2004) 348-359
28. Ron D., Napolitano E.W., Voronova A., Vasquez N.J., Roberts D.N., Calio B.L., Caothien R.H., Petitford S.M., Wellik S., Mandac J.B., and Kauvar L.M. Direct interaction in T-cells between thetaPKC and the tyrosine kinase p59fyn. J. Biol. Chem. 274 (1999) 19003-19010
29. Tseng P., Lin H., Hu H., Wang C., Zhu M.X., and Chen C. The canonical transient receptor potential 6 channel as a putative phosphatidylinositol 3,4,5-trisphosphate-sensitive calcium entry system. Biochemistry 43 (2004) 11701-11708
30. 2+ entry mechanism. J. Biol. Chem. 276 (2001) 14814-14820
31. Lam R.S., Shumilina E., Matzner N., Zemtsova M., Sobiesiak M., Lang C., Felder E., Dietl P., Huber S.M., and Lang F. Phosphatidylinositol-3-kinase regulates mast cell ion channel activity. Cell. Physiol. Biochem. 22 (2008) 169-176