Activation of the PI3K pathway increases TLR-induced TNF-and IL-6 but reduces IL-1β production in mast cells

Cellular Signalling

Volumn 23, Issue 5, 2011, Pages 866-875

  Hochdörfer, Thomas ^a   Kuhny, Marcel ^a   Zorn, Carolin N ^a   Hendriks, Rudi W ^b   Vanhaesebroeck, Bart ^c   Bohnacker, Thomas ^d   Krystal, Gerald ^e   Huber, Michael ^a  

^a UNIVERSITY HOSPITAL RWTH AACHEN   (Germany)

^b ERASMUS MEDICAL CENTER   (Netherlands)

^c QUEEN MARY UNIVERSITY OF LONDON   (United Kingdom)

^d UNIVERSITY OF BASEL   (Switzerland)

^e BRITISH COLUMBIA CANCER AGENCY   (Canada)

Author keywords

C kit; Fc R1; IGF 1; IL 33; Insulin; Lipopolysaccharide

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; ANTIGEN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INSULIN; INTERLEUKIN 1BETA; INTERLEUKIN 33; INTERLEUKIN 33 RECEPTOR; INTERLEUKIN 6; LIPOPOLYSACCHARIDE; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3 KINASE INHIBITOR; PROTEIN 100 DELTA; PROTEIN SHIP1; SOMATOMEDIN C; STEEL FACTOR; TOLL LIKE RECEPTOR; TOLL LIKE RECEPTOR 2; TUMOR NECROSIS FACTOR; UNCLASSIFIED DRUG; WORTMANNIN;

ANIMAL CELL; ARTICLE; BONE MARROW CELL; CELL ACTIVATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; DRUG ACTIVITY; ENZYME ACTIVATION; MALE; MAST CELL; MOUSE; NONHUMAN; PERITONEUM MAST CELL; PRIORITY JOURNAL; SIGNAL TRANSDUCTION;

ANIMALS; INSULIN-LIKE GROWTH FACTOR I; INTERLEUKIN-1BETA; INTERLEUKIN-6; LIPOPOLYSACCHARIDES; MAST CELLS; MICE; PHOSPHATIDYLINOSITOL 3-KINASES; PHOSPHORIC MONOESTER HYDROLASES; RECEPTORS, INTERLEUKIN; SIGNAL TRANSDUCTION; TOLL-LIKE RECEPTOR 2; TOLL-LIKE RECEPTORS; TUMOR NECROSIS FACTOR-ALPHA;

BACTERIA (MICROORGANISMS); MURINAE;

EID: 79951955543     PISSN: 08986568     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cellsig.2011.01.012     Document Type: Article

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