A novel spider peptide toxin suppresses tumor growth through dual signaling pathways

Current Molecular Medicine

Volumn 12, Issue 10, 2012, Pages 1350-1360

  Liu, Z ^a   Deng, M ^a,b   Xiang, J ^a   Ma, H ^a   Hu, W ^a   Zhao, Y ^a   Li, D W C ^a,b   Liang, S ^a  

^a HUNAN NORMAL UNIVERSITY   (China)

^b UNIVERSITY OF NEBRASKA MEDICAL CENTER   (United States)

Author keywords

Apoptosis; Cell proliferation; Gene expression; Mitochondria; P27; Signal transduction; Spider peptide toxin; Tumor suppression

Indexed keywords

CASPASE 3; CYTOCHROME C; LYCOSIN 1; PROTEIN P19; PROTEIN P21; PROTEIN P27; SPIDER VENOM; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CANCER INHIBITION; CARCINOGENESIS; CELL DEATH; CELL PROLIFERATION; CELL STRUCTURE; CELL VABILITY; CONTROLLED STUDY; FLOW CYTOMETRY; FLUORESCENCE MICROSCOPY; HUMAN; HUMAN CELL; INTERNALIZATION; LUNG ADENOCARCINOMA; MOUSE; NICK END LABELING; NONHUMAN; PROTEIN EXPRESSION; PROTEIN PURIFICATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; TUMOR VOLUME; WESTERN BLOTTING;

APOPTOSIS; CASPASE 3; CELL LINE, TUMOR; CELL PROLIFERATION; CELL TRANSFORMATION, NEOPLASTIC; CYTOCHROMES C; HELA CELLS; HUMANS; MITOCHONDRIA; NEOPLASMS; PROLIFERATING CELL NUCLEAR ANTIGEN; PROTEIN CONFORMATION; RNA INTERFERENCE; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; SPIDER VENOMS;

ARANEAE; LYCOSA SINGORIENSIS;

EID: 84870187949     PISSN: 15665240     EISSN: 18755666     Source Type: Journal    
DOI: 10.2174/156652412803833643     Document Type: Article

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