The p53-Bak apoptotic signaling axis plays an essential role in regulating differentiation of the ocular lens

Current Molecular Medicine

Volumn 12, Issue 8, 2012, Pages 901-916

  Deng, M ^a   Chen, P ^b   Liu, F ^b   Fu, S ^b   Tang, H ^b   Fu, Y ^b   Xiong, Z ^b   Hui, S ^b   Ji, W ^a   Zhang, X ^a   Zhang, L ^c   Gong, L ^a   Hu, X ^a,b   Hu, W ^a,b   Sun, S ^d   Liu, J ^e   Xiao, L ^a,b   Liu, W B ^b   Xiao, Y M ^b   Liu, S J ^b   Liu, Y ^b   Li, D W C ^a,b   more..

^a UNIVERSITY OF NEBRASKA MEDICAL CENTER   (United States)

^b HUNAN NORMAL UNIVERSITY   (China)

^c FUDAN UNIVERSITY   (China)

^d CENTRAL SOUTH UNIVERSITY   (China)

^e INSTITUTE OF TROPICAL BIOSCIENCE AND BIOTECHNOLOGY   (China)

Author keywords

Apoptosis; Bak; Cataract; Cell differentiation; Gene expression; Lens; p53; Signaling pathway; Transcription regulation; Tumor suppressor

Indexed keywords

FIBROBLAST GROWTH FACTOR 2; PROTEIN BAK; PROTEIN P53;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL DIFFERENTIATION; CELL NUCLEUS; CONTROLLED STUDY; CYTOPLASM; FEMALE; HUMAN; IN VITRO STUDY; KNOCKOUT MOUSE; LENS IMPLANT; MOUSE; NONHUMAN; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION;

ANIMALS; APOPTOSIS; BASE SEQUENCE; BCL-2 HOMOLOGOUS ANTAGONIST-KILLER PROTEIN; BETA-CRYSTALLINS; CELL DIFFERENTIATION; CELL LINE; CELL NUCLEUS; CYTOPLASM; EPITHELIAL CELLS; FIBROBLAST GROWTH FACTOR 2; GENE EXPRESSION; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GENE KNOCKDOWN TECHNIQUES; HUMANS; LENS, CRYSTALLINE; MICE; MICE, KNOCKOUT; PHOSPHORYLATION; PROMOTER REGIONS, GENETIC; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTEIN TRANSPORT; RNA INTERFERENCE; SIGNAL TRANSDUCTION; TUMOR SUPPRESSOR PROTEIN P53;

MUS;

EID: 84866526095     PISSN: 15665240     EISSN: 18755666     Source Type: Journal    
DOI: 10.2174/156652412802480899     Document Type: Article

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