By improving regional cortical blood flow, attenuating mitochondrial dysfunction and sequential apoptosis galangin acts as a potential neuroprotective agent after acute ischemic stroke

Molecules

Volumn 17, Issue 11, 2012, Pages 13403-13423

  Li, Shaojing ^a   Wu, Chuanhong ^a   Zhu, Li ^a,b   Gao, Jian ^c   Fang, Jing ^a   Li, Defeng ^a   Fu, Meihong ^a   Liang, Rixin ^a   Wang, Lan ^a   Cheng, Ming ^a   Yang, Hongjun ^a  

^a INSTITUTE OF CHINESE MATERIA MEDICA   (China)

^b JIANGXI UNIVERSITY OF TRADITIONAL CHINESE MEDICINE   (China)

^c HEBEI UNIVERSITY   (China)

Author keywords

Cerebral ischemia; Galangin; Mitochondria

Indexed keywords

ADPRT PROTEIN, RAT; BAX PROTEIN, RAT; CASP3 PROTEIN, RAT; CASPASE 3; CYTOCHROME C; FLAVONOID; GALANGIN; GINKGO BILOBA EXTRACT 761; NEUROPROTECTIVE AGENT; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PLANT EXTRACT; PROTEIN BAX; PROTEIN BCL 2; REACTIVE OXYGEN METABOLITE;

ACUTE DISEASE; ANIMAL; APOPTOSIS; ARTICLE; BLOOD FLOW; BRAIN CORTEX; CEREBRAL ARTERY DISEASE; DRUG EFFECT; MALE; MEMBRANE FLUIDITY; METABOLISM; MITOCHONDRIAL MEMBRANE POTENTIAL; MITOCHONDRION; MITOCHONDRION SWELLING; OXIDATIVE STRESS; PATHOLOGY; PATHOPHYSIOLOGY; RAT; SPRAGUE DAWLEY RAT; VASCULARIZATION;

ACUTE DISEASE; ANIMALS; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; CASPASE 3; CEREBRAL CORTEX; CYTOCHROMES C; FLAVONOIDS; INFARCTION, MIDDLE CEREBRAL ARTERY; MALE; MEMBRANE FLUIDITY; MEMBRANE POTENTIAL, MITOCHONDRIAL; MITOCHONDRIA; MITOCHONDRIAL SWELLING; NEUROPROTECTIVE AGENTS; OXIDATIVE STRESS; PLANT EXTRACTS; POLY(ADP-RIBOSE) POLYMERASES; PROTO-ONCOGENE PROTEINS C-BCL-2; RATS; RATS, SPRAGUE-DAWLEY; REACTIVE OXYGEN SPECIES; REGIONAL BLOOD FLOW;

EID: 84870186769     PISSN: None     EISSN: 14203049     Source Type: Journal    
DOI: 10.3390/molecules171113403     Document Type: Article

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