The flavonoid scaffold as a template for the design of modulators of the vascular Ca v1.2 channels

British Journal of Pharmacology

Volumn 164, Issue 6, 2011, Pages 1684-1697

  Saponara, S ^a   Carosati, E ^b   Mugnai, P ^a   Sgaragli, G ^a   Fusi, F ^a  

^a UNIVERSITY OF SIENA   (Italy)

^b UNIVERSITY OF PERUGIA   (Italy)

Author keywords

Ca v1.2 channel current; myricetin; quercetin; rat tail artery myocyte; whole cell patch clamp

Indexed keywords

2',5,7 TRIHYDROXYFLAVONE; 3 METHYL GALANGIN; 3,4' DIHYDROXYFLAVONE; 3,6,4' TRIHYDROXYFLAVONE; 6 HYDROXYFLAVONE; APIGENIN; AURANTIIN; BAICALEIN; CALCIUM CHANNEL; CHRYSIN; CRYSIN; FLAVONOID; GALANGIN; GENISTEIN; ISORHAMNETIN; KAEMPFEROL; LUTEOLIN; MORIN; MYRICETIN; NARINGENIN; PROTEIN KINASE C; PROTEIN TYROSINE KINASE; QUERCETIN; RESOKAEMPFEROL; RUTOSIDE; SCUTELLAREIN; TAMARIXETIN; TAXIFOLIN; UNCLASSIFIED DRUG; UNINDEXED DRUG; VOLTAGE DEPENDENT CALCIUM CHANNEL 1.2;

ANIMAL CELL; ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; DRUG DETERMINATION; DRUG INHIBITION; DRUG STRUCTURE; HYDROXYLATION; MALE; MOLECULAR DYNAMICS; MUSCLE CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; TREATMENT RESPONSE;

ANIMALS; ARTERIES; CALCIUM CHANNELS, L-TYPE; FLAVONOIDS; MALE; MODELS, MOLECULAR; MOLECULAR STRUCTURE; MYOCYTES, SMOOTH MUSCLE; PATCH-CLAMP TECHNIQUES; PRINCIPAL COMPONENT ANALYSIS; RATS; RATS, SPRAGUE-DAWLEY; TAIL;

EID: 80054991820     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1111/j.1476-5381.2011.01476.x     Document Type: Article

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