Vasorelaxant effect of the flavonoid galangin on isolated rat thoracic aorta

Life Sciences

Volumn 78, Issue 8, 2006, Pages 825-830

  Morello, Silvana ^a   Vellecco, Valentina ^a   Alfieri, Alessio ^a   Mascolo, Nicola ^a   Cicala, Carla ^a  

^a UNIVERSITY OF NAPLES FEDERICO II   (Italy)

Author keywords

Aorta; Calcium; Flavonoids; Galangin; Nitric oxide; Propolis; Vasorelaxation

Indexed keywords

9 (TETRAHYDRO 2 FURYL)ADENINE; CALCIUM ION; FLAVONOID; GALANGIN; INDOMETACIN; N(G) NITROARGININE METHYL ESTER; NITRIC OXIDE; PHENYLEPHRINE; POTASSIUM CHLORIDE;

ANIMAL TISSUE; AORTA MEDIA; ARTICLE; CONTROLLED STUDY; DRUG ACTIVITY; DRUG ANTAGONISM; DRUG EFFECT; DRUG INHIBITION; MALE; NONHUMAN; RAT; THORACIC AORTA; VASCULAR RING; VASODILATATION;

ADENINE; ANIMALS; AORTA, THORACIC; CALCIUM; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG COMBINATIONS; FLAVONOIDS; INDOMETHACIN; MALE; NG-NITROARGININE METHYL ESTER; NITRIC OXIDE; PHENYLEPHRINE; POTASSIUM CHLORIDE; PROPOLIS; RATS; RATS, WISTAR; VASODILATION; VASODILATOR AGENTS;

ANIMALIA;

EID: 30544453851     PISSN: 00243205     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.lfs.2005.05.072     Document Type: Article

References (18)

1. M. Ajay, A.U. Gilani, and M.R. Mustafa Effects of flavonoids on vascular smooth muscle of the isolated rat thoracic aorta Life Sciences 74 2003 603 612
2. R. Capasso, and I.A. Tavares Effect of the flavonoid galangin on urinary bladder rat contractility in vitro Pharmacy and Pharmacology 54 8 2002 1147 1150
3. C.K. Chen, and C.R. Pace-Asciak Vasorelaxing activity of resveratrol and quercetin in isolated rat aorta General Pharmacology 27 2 1996 363 366
4. 4-induced microsomal lipid peroxidation Experientia 47 2 1991 195 199
5. C. Cicala, S. Morello, C. Iorio, R. Papasso, F. Borrelli, and N. Mascolo Vascular effects of caffeic acid phenethyl ester (CAPE) on isolated rat thoracic aorta Life Sciences 73 1 2003 73 80
6. G. Di Carlo, N. Mascolo, A.A. Izzo, and F. Capasso Flavonoids: old and new aspects of a class of natural therapeutic drugs Life Sciences 65 4 1999 337 353
7. M. Gabor, and Z. Razga Effect of benzopyrone derivatives on simultaneously induced croton oil ear oedema and carrageenin paw oedema in rats Acta Physiologica Hungarica 77 3-4 1991 197 207
8. T. Godfraind, R. Miller, and M. Wibo Calcium antagonism and calcium entry blockade Pharmacological Reviews 38 4 1986 324 416
9. 2+ indicators with greatly improved fluorescence properties Journal of Biological Chemistry 260 6 1985 3440 3450
10. B.H. Havsteen Flavonoids, a class of natural products of high pharmacological potency Biochemical Pharmacology 32 7 1983 1141 1148
11. C.G.M. Heijnen, G.R. Haenen, F.A. van Acker, W.J. van der Vijgh, and A. Bast Flavonoids as peroxynitrite scavengers: the role of the hydroxyl groups Toxicology In Vitro 15 1 2001 3 6
12. M.D. Herrera, A. Zarzuelo, J. Jimenez, E. Marhuenda, and J. Duarte Effects of flavonoids on rat aortic smooth muscle contractility: structure-activity relationship General Pharmacology 27 2 1996 273 277
13. P.M. Hudgins, and G. Weiss Differential effects of calcium removal upon vascular smooth muscle contraction induced by norepinephrine, histamine and potassium Journal of Pharmacological and Experimental Therapeutics 159 1 1968 91 97
14. Y. Imamura, T. Migita, Y. Uriu, M. Otagiri, and T. Okawara Inhibitory effects of flavonoids on rabbit heart carbonyl reductase Journal of Biochemistry 127 4 2000 653 658
15. T.P. Misko, R.J. Schilling, D. Salvemini, W.M. Moore, and M.G. Currie A fluorometric assay for the measurement of nitrite in biological samples Analytical Biochemistry 214 1 1993 11 16
16. A. Rossi, A. Ligresti, R. Longo, A. Russo, F. Borrelli, and L. Sautebin The inhibitory effect of propolis and caffeic acid phenethyl ester on cyclooxygenase activity in J774 macrophages Phytomedicine 9 6 2002 530 535
17. L.L. Thomsen, L.M. Ching, and B.C. Baguley Evidence for the production of nitric oxide by activated macrophages treated with the antitumor agents flavone-8-acetic acid and xanthenone-4-acetic acid Cancer Research 50 21 1990 6966 6970
18. 2+ in aortic smooth muscle cells from DOCA-hypertensive rats Brazilian Journal of Medical and Biological Research 30 2 1997 257 267