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Volumn 153, Issue 12, 2012, Pages 6114-6125

Thyroid peroxidase gene expression is induced by lipopolysaccharide involving nuclear factor (NF)-κB p65 subunit phosphorylation

Author keywords

[No Author keywords available]

Indexed keywords

LIPOPOLYSACCHARIDE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE P38; THYROID TRANSCRIPTION FACTOR 1; THYROID TRANSCRIPTION FACTOR 2; TRANSCRIPTION FACTOR RELA;

EID: 84870174952     PISSN: 00137227     EISSN: 19457170     Source Type: Journal    
DOI: 10.1210/en.2012-1567     Document Type: Article
Times cited : (23)

References (63)
  • 1
    • 30544439048 scopus 로고    scopus 로고
    • Structural and functional aspects of thyroid peroxidase
    • Ruf J, Carayon P 2006 Structural and functional aspects of thyroid peroxidase. Arch Biochem Biophys 445:269-277
    • (2006) Arch Biochem Biophys , vol.445 , pp. 269-277
    • Ruf, J.1    Carayon, P.2
  • 2
    • 23044467558 scopus 로고    scopus 로고
    • Intracellular trafficking of thyroid peroxidase to the cell surface
    • Kuliawat R, Ramos-Castañeda J, Liu Y, Arvan P 2005 Intracellular trafficking of thyroid peroxidase to the cell surface. J Biol Chem 280:27713-27718
    • (2005) J Biol Chem , vol.280 , pp. 27713-27718
    • Kuliawat, R.1    Ramos-Castañeda, J.2    Liu, Y.3    Arvan, P.4
  • 3
    • 77952876664 scopus 로고    scopus 로고
    • Genetics and phenomics of hypothyroidism and goiter due to TPO mutations
    • Ris-Stalpers C, Bikker H 2010 Genetics and phenomics of hypothyroidism and goiter due to TPO mutations. Mol Cell Endocrinol 322:38-43
    • (2010) Mol Cell Endocrinol , vol.322 , pp. 38-43
    • Ris-Stalpers, C.1    Bikker, H.2
  • 4
    • 35948935940 scopus 로고    scopus 로고
    • Thyroid peroxidase as an autoantigen
    • McLachlan SM, Rapoport B 2007 Thyroid peroxidase as an autoantigen. Thyroid 17:939-948
    • (2007) Thyroid , vol.17 , pp. 939-948
    • McLachlan, S.M.1    Rapoport, B.2
  • 5
    • 38049061134 scopus 로고    scopus 로고
    • Analytical aspects of thyroid antibodies estimation
    • Sinclair D 2008 Analytical aspects of thyroid antibodies estimation. Autoimmunity 41:46-54
    • (2008) Autoimmunity , vol.41 , pp. 46-54
    • Sinclair, D.1
  • 6
    • 0026593301 scopus 로고
    • Cell-type-specific expression of the rat thyroperoxidase promoter indicates common mechanisms for thyroid-specific gene expression
    • Francis-Lang H, Price M, Polycarpou-Schwarz M, Di Lauro R 1992 Cell-type-specific expression of the rat thyroperoxidase promoter indicates common mechanisms for thyroid-specific gene expression. Mol Cell Biol 12:576-588
    • (1992) Mol Cell Biol , vol.12 , pp. 576-588
    • Francis-Lang, H.1    Price, M.2    Polycarpou-Schwarz, M.3    Di Lauro, R.4
  • 7
    • 0027507599 scopus 로고
    • Identification of a cis-regulatory element and a thyroid-specific nuclear factor mediating the hormonal regulation of rat thyroid peroxidase promoter activity
    • Aza-Blanc P, Di Lauro R, Santisteban P 1993 Identification of a cis-regulatory element and a thyroid-specific nuclear factor mediating the hormonal regulation of rat thyroid peroxidase promoter activity. Mol Endocrinol 7:1297-1306
    • (1993) Mol Endocrinol , vol.7 , pp. 1297-1306
    • Aza-Blanc, P.1    Di Lauro, R.2    Santisteban, P.3
  • 10
    • 0035202331 scopus 로고    scopus 로고
    • A unique combination of transcription factors controls differentiation of thyroid cells
    • Damante G, Tell G, Di Lauro R 2001 A unique combination of transcription factors controls differentiation of thyroid cells. Prog Nucleic Acid Res Mol Biol 66:307-356
    • (2001) Prog Nucleic Acid Res Mol Biol , vol.66 , pp. 307-356
    • Damante, G.1    Tell, G.2    Di Lauro, R.3
  • 11
    • 5444271023 scopus 로고    scopus 로고
    • Thyroid development and its disorders: Genetics and molecular mechanisms
    • De Felice M, Di Lauro R 2004 Thyroid development and its disorders: genetics and molecular mechanisms. Endocr Rev 25:722-746
    • (2004) Endocr Rev , vol.25 , pp. 722-746
    • De Felice, M.1    Di Lauro, R.2
  • 12
    • 0033591246 scopus 로고    scopus 로고
    • The interaction between the forkhead thyroid transcription factor TTF-2 and the constitutive factor CTF/NF-1 is required for efficient hormonal regulation of the thyroperoxidase gene transcription
    • Ortiz L, Aza-Blanc P, Zannini M, Cato AC, Santisteban P 1999 The interaction between the forkhead thyroid transcription factor TTF-2 and the constitutive factor CTF/NF-1 is required for efficient hormonal regulation of the thyroperoxidase gene transcription. J Biol Chem 274:15213-15221
    • (1999) J Biol Chem , vol.274 , pp. 15213-15221
    • Ortiz, L.1    Aza-Blanc, P.2    Zannini, M.3    Cato, A.C.4    Santisteban, P.5
  • 13
    • 3142724031 scopus 로고    scopus 로고
    • Toll-like receptor signalling
    • Akira S, Takeda K 2004 Toll-like receptor signalling. Nat Rev Immunol 4:499-511
    • (2004) Nat Rev Immunol , vol.4 , pp. 499-511
    • Akira, S.1    Takeda, K.2
  • 15
    • 1642384019 scopus 로고    scopus 로고
    • Innate recognition of lipopolysaccharide by Toll-like receptor 4-MD-2
    • Miyake K 2004 Innate recognition of lipopolysaccharide by Toll-like receptor 4-MD-2. Trends Microbiol 12:186-192
    • (2004) Trends Microbiol , vol.12 , pp. 186-192
    • Miyake, K.1
  • 16
    • 0035104119 scopus 로고    scopus 로고
    • LPS induction of gene expression in human monocytes
    • Guha M, Mackman N 2001 LPS induction of gene expression in human monocytes. Cell Signal 13:85-94
    • (2001) Cell Signal , vol.13 , pp. 85-94
    • Guha, M.1    Mackman, N.2
  • 17
    • 14244252223 scopus 로고    scopus 로고
    • Lipopolysaccharide directly stimulates cortisol secretion by human adrenal cells by a cyclooxygenase-dependent mechanism
    • Vakharia K, Hinson JP 2005 Lipopolysaccharide directly stimulates cortisol secretion by human adrenal cells by a cyclooxygenase-dependent mechanism. Endocrinology 146:1398-1402
    • (2005) Endocrinology , vol.146 , pp. 1398-1402
    • Vakharia, K.1    Hinson, J.P.2
  • 18
    • 0043168062 scopus 로고    scopus 로고
    • Evidence of expression of endotoxin receptors CD14, toll-like receptors TLR4 and TLR2 and associated molecule MD-2 and of sensitivity to endotoxin (LPS) in islet β cells
    • Vives-Pi M, Somoza N, Fernández-Alvarez J, Vargas F, Caro P, Alba A, Gomis R, Labeta MO, Pujol-Borrell R 2003 Evidence of expression of endotoxin receptors CD14, toll-like receptors TLR4 and TLR2 and associated molecule MD-2 and of sensitivity to endotoxin (LPS) in islet β cells. Clin Exp Immunol 133:208-218
    • (2003) Clin Exp Immunol , vol.133 , pp. 208-218
    • Vives-Pi, M.1    Somoza, N.2    Fernández-Alvarez, J.3    Vargas, F.4    Caro, P.5    Alba, A.6    Gomis, R.7    Labeta, M.O.8    Pujol-Borrell, R.9
  • 19
    • 34447302602 scopus 로고    scopus 로고
    • Leptin-dependent toll-like receptor expression and responsiveness in preadipocytes and adipocytes
    • Batra A, Pietsch J, Fedke I, Glauben R, Okur B, Stroh T, Zeitz M, Siegmund B 2007 Leptin-dependent toll-like receptor expression and responsiveness in preadipocytes and adipocytes. Am J Pathol 170:1931-1941
    • (2007) Am J Pathol , vol.170 , pp. 1931-1941
    • Batra, A.1    Pietsch, J.2    Fedke, I.3    Glauben, R.4    Okur, B.5    Stroh, T.6    Zeitz, M.7    Siegmund, B.8
  • 21
    • 79952044141 scopus 로고    scopus 로고
    • Toll-like receptor 4 (TLR4) expression in human and murine pancreatic β-cells affects cell viability and insulin homeostasis
    • Garay-Malpartida HM, Mourão RF, Mantovani M, Santos IA, Sogayar MC, Goldberg AC 2011 Toll-like receptor 4 (TLR4) expression in human and murine pancreatic β-cells affects cell viability and insulin homeostasis. BMC Immunol 12:18
    • (2011) BMC Immunol , vol.12 , pp. 18
    • Garay-Malpartida, H.M.1    Mourão, R.F.2    Mantovani, M.3    Santos, I.A.4    Sogayar, M.C.5    Goldberg, A.C.6
  • 23
    • 33745168333 scopus 로고    scopus 로고
    • Bacterial lipopolysaccharide stimulates the thyrotropin-dependent thyroglobulin gene expression at the transcriptional level by involving the transcription factors thyroid transcription factor-1 and paired box domain transcription factor 8
    • Vélez ML, Costamagna E, Kimura ET, Fozzatti L, Pellizas CG, Montesinos MM, Lucero AM, Coleoni AH, Santisteban P, Masini-Repiso AM 2006 Bacterial lipopolysaccharide stimulates the thyrotropin-dependent thyroglobulin gene expression at the transcriptional level by involving the transcription factors thyroid transcription factor-1 and paired box domain transcription factor 8. Endocrinology 147:3260-3275
    • (2006) Endocrinology , vol.147 , pp. 3260-3275
    • Vélez, M.L.1    Costamagna, E.2    Kimura, E.T.3    Fozzatti, L.4    Pellizas, C.G.5    Montesinos, M.M.6    Lucero, A.M.7    Coleoni, A.H.8    Santisteban, P.9    Masini-Repiso, A.M.10
  • 24
    • 34247566510 scopus 로고    scopus 로고
    • The family of five: TIR-domain-containing adaptors in Toll-like receptor signalling
    • O'Neill LA, Bowie AG 2007 The family of five: TIR-domain-containing adaptors in Toll-like receptor signalling. Nat Rev Immunol 7:353-364
    • (2007) Nat Rev Immunol , vol.7 , pp. 353-364
    • O'Neill, L.A.1    Bowie, A.G.2
  • 25
    • 67650724069 scopus 로고    scopus 로고
    • Regulation and function of NF-κB transcription factors in the immune system
    • Vallabhapurapu S, Karin M 2009 Regulation and function of NF-κB transcription factors in the immune system. Annu Rev Immunol 27:693-733
    • (2009) Annu Rev Immunol , vol.27 , pp. 693-733
    • Vallabhapurapu, S.1    Karin, M.2
  • 26
    • 38849199203 scopus 로고    scopus 로고
    • Shared principles in NF-κB signaling
    • Hayden MS, Ghosh S 2008 Shared principles in NF-κB signaling. Cell 132:344-362
    • (2008) Cell , vol.132 , pp. 344-362
    • Hayden, M.S.1    Ghosh, S.2
  • 27
    • 0036234459 scopus 로고    scopus 로고
    • Missing pieces in the NF-κB puzzle
    • Ghosh S, Karin M 2002 Missing pieces in the NF-κB puzzle. Cell 109(Suppl):S81-S96
    • (2002) Cell , vol.109 , Issue.SUPPL.
    • Ghosh, S.1    Karin, M.2
  • 28
    • 33845768987 scopus 로고    scopus 로고
    • Integrating cell-signalling pathways with NF-κB and IKK function
    • Perkins ND 2007 Integrating cell-signalling pathways with NF-κB and IKK function. Nat Rev Mol Cell Biol 8:49-62
    • (2007) Nat Rev Mol Cell Biol , vol.8 , pp. 49-62
    • Perkins, N.D.1
  • 32
    • 0034793849 scopus 로고    scopus 로고
    • Regulation of thyroid cell proliferation by TSH and other factors: A critical evaluation of in vitro models
    • Kimura T, Van Keymeulen A, Golstein J, Fusco A, Dumont JE, Roger PP 2001 Regulation of thyroid cell proliferation by TSH and other factors: a critical evaluation of in vitro models. Endocr Rev 22:631-656
    • (2001) Endocr Rev , vol.22 , pp. 631-656
    • Kimura, T.1    Van Keymeulen, A.2    Golstein, J.3    Fusco, A.4    Dumont, J.E.5    Roger, P.P.6
  • 34
    • 0036143654 scopus 로고    scopus 로고
    • P38-Dependent marking of inflammatory genes for increased NF-κB recruitment
    • Saccani S, Pantano S, Natoli G 2002 p38-Dependent marking of inflammatory genes for increased NF-κB recruitment. Nat Immunol 3:69-75
    • (2002) Nat Immunol , vol.3 , pp. 69-75
    • Saccani, S.1    Pantano, S.2    Natoli, G.3
  • 35
    • 0032698069 scopus 로고    scopus 로고
    • The p38 mitogen-activated protein kinase is required for NF-κB-dependent gene expression. The role of TATA-binding protein (TBP)
    • Carter AB, Knudtson KL, Monick MM, Hunninghake GW 1999 The p38 mitogen-activated protein kinase is required for NF-κB-dependent gene expression. The role of TATA-binding protein (TBP). J Biol Chem 274:30858-30863
    • (1999) J Biol Chem , vol.274 , pp. 30858-30863
    • Carter, A.B.1    Knudtson, K.L.2    Monick, M.M.3    Hunninghake, G.W.4
  • 37
    • 0037851769 scopus 로고    scopus 로고
    • IKK β plays an essential role in the phosphorylation of RelA/p65 on serine 536 induced by lipopolysaccharide
    • Yang F, Tang E, Guan K, Wang CY 2003 IKK β plays an essential role in the phosphorylation of RelA/p65 on serine 536 induced by lipopolysaccharide. J Immunol 170:5630-5635
    • (2003) J Immunol , vol.170 , pp. 5630-5635
    • Yang, F.1    Tang, E.2    Guan, K.3    Wang, C.Y.4
  • 38
    • 21244503601 scopus 로고    scopus 로고
    • Bruton's tyrosine kinase is involved in p65-mediated transactivation and phosphorylation of p65 on serine 536 during NFκB activation by lipopolysaccharide
    • Doyle SL, Jefferies CA, O'Neill LA 2005 Bruton's tyrosine kinase is involved in p65-mediated transactivation and phosphorylation of p65 on serine 536 during NFκB activation by lipopolysaccharide. J Biol Chem 280:23496-23501
    • (2005) J Biol Chem , vol.280 , pp. 23496-23501
    • Doyle, S.L.1    Jefferies, C.A.2    O'Neill, L.A.3
  • 41
    • 79959401429 scopus 로고    scopus 로고
    • Toll-like receptor-initiated testicular innate immune responses in mouse Leydig cells
    • Shang T, Zhang X, Wang T, Sun B, Deng T, Han D 2011 Toll-like receptor-initiated testicular innate immune responses in mouse Leydig cells. Endocrinology 152:2827-2836
    • (2011) Endocrinology , vol.152 , pp. 2827-2836
    • Shang, T.1    Zhang, X.2    Wang, T.3    Sun, B.4    Deng, T.5    Han, D.6
  • 42
    • 35948953900 scopus 로고    scopus 로고
    • The genetic basis of thyroid autoimmunity
    • Jacobson EM, Tomer Y 2007 The genetic basis of thyroid autoimmunity. Thyroid 17:949-961
    • (2007) Thyroid , vol.17 , pp. 949-961
    • Jacobson, E.M.1    Tomer, Y.2
  • 43
    • 0024332927 scopus 로고
    • The causes of autoimmune thyroid disease
    • DeGroot LJ, Quintans J 1989 The causes of autoimmune thyroid disease. Endocr Rev 10:537-562
    • (1989) Endocr Rev , vol.10 , pp. 537-562
    • DeGroot, L.J.1    Quintans, J.2
  • 44
    • 67349199596 scopus 로고    scopus 로고
    • The etiology of autoimmune thyroid disease: A story of genes and environment
    • Tomer Y, Huber A 2009 The etiology of autoimmune thyroid disease: a story of genes and environment. J Autoimmun 32:231-239
    • (2009) J Autoimmun , vol.32 , pp. 231-239
    • Tomer, Y.1    Huber, A.2
  • 45
    • 34347255396 scopus 로고    scopus 로고
    • Suppression of iodide uptake and thyroid hormone synthesis with stimulation of the type I interferon system by double-stranded ribonucleic acid in cultured human thyroid follicles
    • Yamazaki K, Suzuki K, Yamada E, Yamada T, Takeshita F, Matsumoto M, Mitsuhashi T, Obara T, Takano K, Sato K 2007 Suppression of iodide uptake and thyroid hormone synthesis with stimulation of the type I interferon system by double-stranded ribonucleic acid in cultured human thyroid follicles. Endocrinology 148:3226-3235
    • (2007) Endocrinology , vol.148 , pp. 3226-3235
    • Yamazaki, K.1    Suzuki, K.2    Yamada, E.3    Yamada, T.4    Takeshita, F.5    Matsumoto, M.6    Mitsuhashi, T.7    Obara, T.8    Takano, K.9    Sato, K.10
  • 46
    • 17844410902 scopus 로고    scopus 로고
    • Thyrocytes express a functional toll-like receptor 3: Overexpression can be induced by viral infection and reversed by phenylmethimazole and is associated with Hashimoto's autoimmune thyroiditis
    • Harii N, Lewis CJ, Vasko V, McCall K, Benavides-Peralta U, Sun X, Ringel MD, Saji M, Giuliani C, Napolitano G, Goetz DJ, Kohn LD 2005 Thyrocytes express a functional toll-like receptor 3: overexpression can be induced by viral infection and reversed by phenylmethimazole and is associated with Hashimoto's autoimmune thyroiditis. Mol Endocrinol 19:1231-1250
    • (2005) Mol Endocrinol , vol.19 , pp. 1231-1250
    • Harii, N.1    Lewis, C.J.2    Vasko, V.3    McCall, K.4    Benavides-Peralta, U.5    Sun, X.6    Ringel, M.D.7    Saji, M.8    Giuliani, C.9    Napolitano, G.10    Goetz, D.J.11    Kohn, L.D.12
  • 47
    • 35449004944 scopus 로고    scopus 로고
    • Toll like receptors and autoimmunity: A critical appraisal
    • Papadimitraki ED, Bertsias GK, Boumpas DT 2007 Toll like receptors and autoimmunity: a critical appraisal. J Autoimmun 29:310-318
    • (2007) J Autoimmun , vol.29 , pp. 310-318
    • Papadimitraki, E.D.1    Bertsias, G.K.2    Boumpas, D.T.3
  • 48
    • 71649099616 scopus 로고    scopus 로고
    • Environmental triggers of autoimmune thyroiditis
    • Burek CL, Talor MV 2009 Environmental triggers of autoimmune thyroiditis. J Autoimmun 33:183-189
    • (2009) J Autoimmun , vol.33 , pp. 183-189
    • Burek, C.L.1    Talor, M.V.2
  • 49
    • 32944464648 scopus 로고    scopus 로고
    • Pathogen recognition and innate immunity
    • Akira S, Uematsu S, Takeuchi O 2006 Pathogen recognition and innate immunity. Cell 124:783-801
    • (2006) Cell , vol.124 , pp. 783-801
    • Akira, S.1    Uematsu, S.2    Takeuchi, O.3
  • 50
    • 5444262511 scopus 로고    scopus 로고
    • Toll-like receptor control of the adaptive immune responses
    • Iwasaki A, Medzhitov R 2004 Toll-like receptor control of the adaptive immune responses. Nat Immunol 5:987-995
    • (2004) Nat Immunol , vol.5 , pp. 987-995
    • Iwasaki, A.1    Medzhitov, R.2
  • 51
    • 0141705416 scopus 로고    scopus 로고
    • Cytokines in thyroid autoimmunity
    • Ajjan RA, Weetman AP 2003 Cytokines in thyroid autoimmunity. Autoimmunity 36:351-359
    • (2003) Autoimmunity , vol.36 , pp. 351-359
    • Ajjan, R.A.1    Weetman, A.P.2
  • 52
  • 53
    • 0032039076 scopus 로고    scopus 로고
    • Phosphorylation of NF-κB p65 by PKA stimulates transcriptional activity by promoting a novel bivalent interaction with the coactivator CBP/p300
    • Zhong H, Voll RE, Ghosh S 1998 Phosphorylation of NF-κB p65 by PKA stimulates transcriptional activity by promoting a novel bivalent interaction with the coactivator CBP/p300. Mol Cell 1:661-671
    • (1998) Mol Cell , vol.1 , pp. 661-671
    • Zhong, H.1    Voll, R.E.2    Ghosh, S.3
  • 54
    • 43649103959 scopus 로고    scopus 로고
    • Protein kinase A-induced phosphorylation of the p65 subunit of nuclear factor-κB promotes Schwann cell differentiation into a myelinating phenotype
    • Yoon C, Korade Z, Carter BD 2008 Protein kinase A-induced phosphorylation of the p65 subunit of nuclear factor-κB promotes Schwann cell differentiation into a myelinating phenotype. J Neurosci 28:3738-3746
    • (2008) J Neurosci , vol.28 , pp. 3738-3746
    • Yoon, C.1    Korade, Z.2    Carter, B.D.3
  • 55
    • 58149471219 scopus 로고    scopus 로고
    • Characterization of thyrotropin receptor antibody-induced signaling cascades
    • Morshed SA, Latif R, Davies TF 2009 Characterization of thyrotropin receptor antibody-induced signaling cascades. Endocrinology 150:519-529
    • (2009) Endocrinology , vol.150 , pp. 519-529
    • Morshed, S.A.1    Latif, R.2    Davies, T.F.3
  • 56
    • 33646831500 scopus 로고    scopus 로고
    • NF-κB regulates phagocytic NADPH oxidase by inducing the expression of gp91phox
    • Anrather J, Racchumi G, Iadecola C 2006 NF-κB regulates phagocytic NADPH oxidase by inducing the expression of gp91phox. J Biol Chem 281:5657-5667
    • (2006) J Biol Chem , vol.281 , pp. 5657-5667
    • Anrather, J.1    Racchumi, G.2    Iadecola, C.3
  • 57
    • 27144459692 scopus 로고    scopus 로고
    • Phosphorylation of RelA/p65 on serine 536 defines an IκBα- independent NF-κB pathway
    • Sasaki CY, Barberi TJ, Ghosh P, Longo DL 2005 Phosphorylation of RelA/p65 on serine 536 defines an IκBα-independent NF-κB pathway. J Biol Chem 280:34538-34547
    • (2005) J Biol Chem , vol.280 , pp. 34538-34547
    • Sasaki, C.Y.1    Barberi, T.J.2    Ghosh, P.3    Longo, D.L.4
  • 58
    • 0036235478 scopus 로고    scopus 로고
    • Involvement of ERK, p38 and NF-κB signal transduction in regulation of TLR2, TLR4 and TLR9 gene expression induced by lipopolysaccharide in mouse dendritic cells
    • An H, Yu Y, Zhang M, Xu H, Qi R, Yan X, Liu S, Wang W, Guo Z, Guo J, Qin Z, Cao X 2002 Involvement of ERK, p38 and NF-κB signal transduction in regulation of TLR2, TLR4 and TLR9 gene expression induced by lipopolysaccharide in mouse dendritic cells. Immunology 106:38-45
    • (2002) Immunology , vol.106 , pp. 38-45
    • An, H.1    Yu, Y.2    Zhang, M.3    Xu, H.4    Qi, R.5    Yan, X.6    Liu, S.7    Wang, W.8    Guo, Z.9    Guo, J.10    Qin, Z.11    Cao, X.12
  • 60
    • 0036794305 scopus 로고    scopus 로고
    • A thyroid-specific far-upstream enhancer in the human sodium/iodide symporter gene requires Pax-8 binding and cyclic adenosine 3′,5′- monophosphate response element-like sequence binding proteins for full activity and is differentially regulated in normal and thyroid cancer cells
    • Taki K, Kogai T, Kanamoto Y, Hershman JM, Brent GA 2002 A thyroid-specific far-upstream enhancer in the human sodium/iodide symporter gene requires Pax-8 binding and cyclic adenosine 3′,5′-monophosphate response element-like sequence binding proteins for full activity and is differentially regulated in normal and thyroid cancer cells. Mol Endocrinol 16:2266-2282
    • (2002) Mol Endocrinol , vol.16 , pp. 2266-2282
    • Taki, K.1    Kogai, T.2    Kanamoto, Y.3    Hershman, J.M.4    Brent, G.A.5
  • 61
    • 0034704085 scopus 로고    scopus 로고
    • Thyroid-stimulating hormone and cyclic AMP activate p38 mitogen-activated protein kinase cascade. Involvement of protein kinase A, rac1, and reactive oxygen species
    • Pomerance M, Abdullah HB, Kamerji S, Correze C, Blondeau JP 2000 Thyroid-stimulating hormone and cyclic AMP activate p38 mitogen-activated protein kinase cascade. Involvement of protein kinase A, rac1, and reactive oxygen species. J Biol Chem 275:40539-40546
    • (2000) J Biol Chem , vol.275 , pp. 40539-40546
    • Pomerance, M.1    Abdullah, H.B.2    Kamerji, S.3    Correze, C.4    Blondeau, J.P.5
  • 63
    • 0037451357 scopus 로고    scopus 로고
    • Transcriptional activation of the NF--B p65 subunit by mitogen- And stress-activated protein kinase-1 (MSK1)
    • Vermeulen L, De Wilde G, Van Damme P, Vanden Berghe W, Haegeman G 2003 Transcriptional activation of the NF--B p65 subunit by mitogen- and stress-activated protein kinase-1 (MSK1). EMBO J 22:1313-1324
    • (2003) EMBO J , vol.22 , pp. 1313-1324
    • Vermeulen, L.1    De Wilde, G.2    Van Damme, P.3    Vanden Berghe, W.4    Haegeman, G.5


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