A thyroid-specific far-upstream enhancer in the human sodium/iodide symporter gene requires Pax-8 binding and cyclic adenosine 3′,5′-monophosphate response element-like sequence binding proteins for full activity and is differentially regulated in normal and thyroid cancer cells

Molecular Endocrinology

Volumn 16, Issue 10, 2002, Pages 2266-2282

  Taki, Katsumi ^a   Kogai, Takahiko ^a   Kanamoto, Yoko ^a   Hershman, Jerome M ^a   Brent, Gregory A ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b VA GREATER LOS ANGELES HEALTHCARE SYSTEM   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING PROTEIN; CYCLIC AMP; CYCLIC AMP DEPENDENT PROTEIN KINASE; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; PROTEIN; TRANSCRIPTION FACTOR PAX8; UNCLASSIFIED DRUG;

ARTICLE; CANCER CELL CULTURE; CANCER GENETICS; CONTROLLED STUDY; CYCLIC AMP RESPONSIVE ELEMENT; ENHANCER REGION; GENE EXPRESSION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN CONFORMATION; THYROID PAPILLARY CARCINOMA;

ACTIVATING TRANSCRIPTION FACTOR 2; ANIMALS; BINDING SITES; CARCINOMA, PAPILLARY; CELL DIFFERENTIATION; CELLS, CULTURED; CYCLIC AMP; CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN; CYCLIC AMP-DEPENDENT PROTEIN KINASES; DNA-BINDING PROTEINS; ENHANCER ELEMENTS (GENETICS); GENE EXPRESSION REGULATION; HUMANS; MUTATION; NUCLEAR PROTEINS; PAIRED BOX TRANSCRIPTION FACTORS; PROMOTER REGIONS (GENETICS); RATS; REFERENCE VALUES; RESPONSE ELEMENTS; SEQUENCE HOMOLOGY, NUCLEIC ACID; SYMPORTERS; THYROID GLAND; THYROID NEOPLASMS; TRANS-ACTIVATORS; TRANSCRIPTION FACTORS;

EID: 0036794305     PISSN: 08888809     EISSN: None     Source Type: Journal    
DOI: 10.1210/me.2002-0109     Document Type: Article

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