Structure-based design of flavone derivatives as c-myc oncogene down-regulators

European Journal of Pharmaceutical Sciences

Volumn 48, Issue 1-2, 2013, Pages 130-141

  Yang, Hui ^a   Zhong, Hai Jing ^b   Leung, Ka Ho ^a   Chan, Daniel Shiu Hin ^a   Ma, Victor Pui Yan ^a   Fu, Wai Chung ^a   Nanjunda, Rupesh ^c   Wilson, W David ^c   Ma, Dik Lung ^a   Leung, Chung Hang ^b  

^a HONG KONG BAPTIST UNIVERSITY   (Hong Kong)

^b University of Macau   (Macao)

^c GEORGIA STATE UNIVERSITY   (United States)

Author keywords

c myc; Flavone derivatives; G quadruplex DNA; Structure based design

Indexed keywords

CATION; FLAVONE DERIVATIVE; GUANINE QUADRUPLEX; MYC PROTEIN; PYRIDINIUM DERIVATIVE;

ARTICLE; CIRCULAR DICHROISM; CONTROLLED STUDY; HUMAN; HUMAN CELL; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN INTERACTION; PROTEIN STRUCTURE; STRUCTURE ANALYSIS; TELOMERE; ULTRAVIOLET RADIATION;

CELL SURVIVAL; CIRCULAR DICHROISM; DOWN-REGULATION; FLAVONES; G-QUADRUPLEXES; GENES, MYC; HEP G2 CELLS; HUMANS; MOLECULAR DOCKING SIMULATION; MOLECULAR STRUCTURE; PROMOTER REGIONS, GENETIC;

EID: 84870157152     PISSN: 09280987     EISSN: 18790720     Source Type: Journal    
DOI: 10.1016/j.ejps.2012.10.010     Document Type: Article

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