Endoplasmic reticulum stress impairs insulin signaling through mitochondrial damage in SH-SY5Y cells

NeuroSignals

Volumn 20, Issue 4, 2012, Pages 265-280

  Koo, Hyun Jung ^a   Piao, Ying ^a   Pak, Youngmi Kim ^a  

^a Kyung Hee University   (South Korea)

Author keywords

Insulin; Mitochondria; Neurodegeneration; Signal transduction; Stress; Thapsigargin

Indexed keywords

ADENOSINE TRIPHOSPHATE; ATRAZINE; INSULIN; INSULIN RECEPTOR SUBSTRATE 1; MITOCHONDRIAL DNA; PROTEIN KINASE B; REACTIVE OXYGEN METABOLITE; THAPSIGARGIN; TUNICAMYCIN;

APOPTOSIS; ARTICLE; CELL VIABILITY; CONTROLLED STUDY; DOWN REGULATION; ENDOPLASMIC RETICULUM STRESS; ENZYME PHOSPHORYLATION; GENE; GENE EXPRESSION; GENE EXPRESSION PROFILING; HUMAN; HUMAN CELL; INTRACELLULAR SIGNALING; MICROARRAY ANALYSIS; MITOCHONDRIAL MEMBRANE POTENTIAL; MITOCHONDRIAL RESPIRATION; MITOCHONDRION; MOLECULAR DYNAMICS; NERVE CELL NECROSIS; NERVE DEGENERATION; NEUROBLASTOMA CELL; NRF 1 GENE; NUCLEOTIDE SEQUENCE; OXIDATIVE STRESS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TFAM GENE;

ADENOSINE TRIPHOSPHATE; APOPTOSIS; ATRAZINE; BLOTTING, WESTERN; CELL LINE; COLORING AGENTS; ENDOPLASMIC RETICULUM STRESS; FLUORESCEINS; HERBICIDES; HUMANS; INSULIN; MICROARRAY ANALYSIS; MITOCHONDRIA; MITOCHONDRIAL MEMBRANES; NEURONS; OXYGEN CONSUMPTION; REAL-TIME POLYMERASE CHAIN REACTION; RECEPTOR CROSS-TALK; SIGNAL TRANSDUCTION; TETRAZOLIUM SALTS; THIAZOLES; TRANSFECTION;

EID: 84870063016     PISSN: 1424862X     EISSN: 14248638     Source Type: Journal    
DOI: 10.1159/000333069     Document Type: Article

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