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Volumn 18, Issue 33, 2012, Pages 5344-5361

Interindividual variability in the efficacy of oral antiplatelet drugs: Definitions, mechanisms and clinical importance

Author keywords

Antiplatelet drugs; Aspirin; Cardiovascular diseases; Clopidogrel; Coronary artery disease; Drug resistance

Indexed keywords

ACETYLSALICYLIC ACID; ANTITHROMBOCYTIC AGENT; CLOPIDOGREL; MULTIDRUG RESISTANCE PROTEIN 4; PLACEBO; PRASUGREL; TICAGRELOR;

EID: 84870047461     PISSN: 13816128     EISSN: 18734286     Source Type: Journal    
DOI: 10.2174/138161212803251925     Document Type: Article
Times cited : (56)

References (307)
  • 1
    • 33646799069 scopus 로고    scopus 로고
    • Global and regional burden of disease and risk factors, 2001: Systematic analysis of population health data
    • Lopez AD, Mathers CD, Ezzati M, Jamison DT, Murray CJ. Global and regional burden of disease and risk factors, 2001: systematic analysis of population health data. Lancet 2006; 367(9524): 1747-57.
    • (2006) Lancet , vol.367 , Issue.9524 , pp. 1747-1757
    • Lopez, A.D.1    Mathers, C.D.2    Ezzati, M.3    Jamison, D.T.4    Murray, C.J.5
  • 3
    • 64649098177 scopus 로고    scopus 로고
    • Optical platelet aggregation versus thromboxane metabolites in healthy individuals and patients with stable coronary artery disease after low-dose aspirin administration
    • Hedegaard SS, Hvas AM, Grove EL, et al. Optical platelet aggregation versus thromboxane metabolites in healthy individuals and patients with stable coronary artery disease after low-dose aspirin administration. Thromb Res 2009; 124(1): 96-100.
    • (2009) Thromb Res , vol.124 , Issue.1 , pp. 96-100
    • Hedegaard, S.S.1    Hvas, A.M.2    Grove, E.L.3
  • 4
    • 60749114799 scopus 로고    scopus 로고
    • Interindividual variability in the response to oral antiplatelet drugs: A position paper of the Working Group on antiplatelet drugs resistance appointed by the Section of Cardiovascular Interventions of the Polish Cardiac Society, endorsed by the Working Group on Thrombosis of the European Society of Cardiology
    • Kuliczkowski W, Witkowski A, Polonski L, et al. Interindividual variability in the response to oral antiplatelet drugs: a position paper of the Working Group on antiplatelet drugs resistance appointed by the Section of Cardiovascular Interventions of the Polish Cardiac Society, endorsed by the Working Group on Thrombosis of the European Society of Cardiology. Eur Heart J 2009; 30(4): 426-35.
    • (2009) Eur Heart J , vol.30 , Issue.4 , pp. 426-435
    • Kuliczkowski, W.1    Witkowski, A.2    Polonski, L.3
  • 5
    • 0015237292 scopus 로고
    • Inhibition of prostaglandin synthesis as a mechanism of action for aspirin-like drugs
    • Vane JR. Inhibition of prostaglandin synthesis as a mechanism of action for aspirin-like drugs. Nat New Biol 1971; 231(25): 232-5.
    • (1971) Nat New Biol , vol.231 , Issue.25 , pp. 232-235
    • Vane, J.R.1
  • 6
    • 0023805341 scopus 로고
    • Randomised trial of intravenous streptokinase, oral aspirin, both, or neither among 17,187 cases of suspected acute myocardial infarction: ISIS-2
    • ISIS-2 (Second International Study of Infarct Survival) Collaborative Group
    • ISIS-2 (Second International Study of Infarct Survival) Collaborative Group. Randomised trial of intravenous streptokinase, oral aspirin, both, or neither among 17,187 cases of suspected acute myocardial infarction: ISIS-2. Lancet 1988; 2(8607): 349-60.
    • (1988) Lancet , vol.2 , Issue.8607 , pp. 349-360
  • 7
    • 0032474229 scopus 로고    scopus 로고
    • ISIS2: 10 year survival among patients with suspected acute myocardial infarction in randomised comparison of intravenous streptokinase, oral aspirin, both, or neither
    • The ISIS-2 (Second International Study of Infarct Survival) Collaborative Group
    • Baigent C, Collins R, Appleby P, Parish S, Sleight P, Peto R. ISIS2: 10 year survival among patients with suspected acute myocardial infarction in randomised comparison of intravenous streptokinase, oral aspirin, both, or neither. The ISIS-2 (Second International Study of Infarct Survival) Collaborative Group. BMJ 1998; 316(7141): 1337-43.
    • (1998) BMJ , vol.316 , Issue.7141 , pp. 1337-1343
    • Baigent, C.1    Collins, R.2    Appleby, P.3    Parish, S.4    Sleight, P.5    Peto, R.6
  • 8
    • 0020528647 scopus 로고
    • Protective effects of aspirin against acute myocardial infarction and death in men with unstable angina. Results of a Veterans Administration Cooperative Study
    • Lewis HD, Jr., Davis JW, Archibald DG, et al. Protective effects of aspirin against acute myocardial infarction and death in men with unstable angina. Results of a Veterans Administration Cooperative Study. N Engl J Med 1983; 309(7): 396-403.
    • (1983) N Engl J Med , vol.309 , Issue.7 , pp. 396-403
    • Lewis Jr., H.D.1    Davis, J.W.2    Archibald, D.G.3
  • 9
    • 0022375287 scopus 로고
    • Aspirin, sulfinpyrazone, or both in unstable angina. Results of a Canadian multicenter trial
    • Cairns JA, Gent M, Singer J, et al. Aspirin, sulfinpyrazone, or both in unstable angina. Results of a Canadian multicenter trial. N Engl J Med 1985; 313(22): 1369-75.
    • (1985) N Engl J Med , vol.313 , Issue.22 , pp. 1369-1375
    • Cairns, J.A.1    Gent, M.2    Singer, J.3
  • 10
    • 0023754429 scopus 로고
    • Aspirin, heparin, or both to treat acute unstable angina
    • Theroux P, Ouimet H, McCans J, et al. Aspirin, heparin, or both to treat acute unstable angina. N Engl J Med 1988; 319(17): 1105-11.
    • (1988) N Engl J Med , vol.319 , Issue.17 , pp. 1105-1111
    • Theroux, P.1    Ouimet, H.2    McCans, J.3
  • 11
    • 0025090942 scopus 로고
    • Risk of myocardial infarction and death during treatment with low dose aspirin and intravenous heparin in men with unstable coronary artery disease
    • The RISC Group
    • The RISC Group. Risk of myocardial infarction and death during treatment with low dose aspirin and intravenous heparin in men with unstable coronary artery disease. Lancet 1990; 336(8719): 827-30.
    • (1990) Lancet , vol.336 , Issue.8719 , pp. 827-830
  • 12
    • 0037065502 scopus 로고    scopus 로고
    • Collaborative metaanalysis of randomised trials of antiplatelet therapy for prevention of death, myocardial infarction, and stroke in high risk patients
    • Antithrombotic Trialists' Collaboration
    • Antithrombotic Trialists' Collaboration. Collaborative metaanalysis of randomised trials of antiplatelet therapy for prevention of death, myocardial infarction, and stroke in high risk patients. BMJ 2002; 324(7329): 71-86.
    • (2002) BMJ , vol.324 , Issue.7329 , pp. 71-86
  • 13
    • 0030911057 scopus 로고    scopus 로고
    • The International Stroke Trial (IST): A randomised trial of aspirin, subcutaneous heparin, both, or neither among 19435 patients with acute ischaemic stroke
    • International Stroke Trial Collaborative Group
    • International Stroke Trial Collaborative Group. The International Stroke Trial (IST): a randomised trial of aspirin, subcutaneous heparin, both, or neither among 19435 patients with acute ischaemic stroke. Lancet 1997; 349(9065): 1569-81.
    • (1997) Lancet , vol.349 , Issue.9065 , pp. 1569-1581
  • 14
    • 0038508970 scopus 로고    scopus 로고
    • The metabolism of clopidogrel is catalyzed by human cytochrome P450 3A and is inhibited by atorvastatin
    • Clarke TA, Waskell LA. The metabolism of clopidogrel is catalyzed by human cytochrome P450 3A and is inhibited by atorvastatin. Drug Metab Dispos 2003; 31(1): 53-9.
    • (2003) Drug Metab Dispos , vol.31 , Issue.1 , pp. 53-59
    • Clarke, T.A.1    Waskell, L.A.2
  • 15
    • 12344294328 scopus 로고    scopus 로고
    • Unstable angina, stroke, myocardial infarction and death in aspirin nonresponders. A prospective, randomized trial. The ASCET (ASpirin non-responsiveness and Clopidogrel Endpoint Trial) design
    • Pettersen AA, Seljeflot I, Abdelnoor M, Arnesen H. Unstable angina, stroke, myocardial infarction and death in aspirin nonresponders. A prospective, randomized trial. The ASCET (ASpirin non-responsiveness and Clopidogrel Endpoint Trial) design. Scand Cardiovasc J 2004; 38(6): 353-6.
    • (2004) Scand Cardiovasc J , vol.38 , Issue.6 , pp. 353-356
    • Pettersen, A.A.1    Seljeflot, I.2    Abdelnoor, M.3    Arnesen, H.4
  • 16
    • 0030590746 scopus 로고    scopus 로고
    • A randomised, blinded, trial of clopidogrel versus aspirin in patients at risk of ischaemic events (CAPRIE)
    • CAPRIE Steering Committee
    • CAPRIE Steering Committee. A randomised, blinded, trial of clopidogrel versus aspirin in patients at risk of ischaemic events (CAPRIE). Lancet 1996; 348(9038): 1329-39.
    • (1996) Lancet , vol.348 , Issue.9038 , pp. 1329-1339
  • 17
    • 0035899289 scopus 로고    scopus 로고
    • Effects of clopidogrel in addition to aspirin in patients with acute coronary syndromes without ST-segment elevation
    • Yusuf S, Zhao F, Mehta SR, Chrolavicius S, Tognoni G, Fox KK. Effects of clopidogrel in addition to aspirin in patients with acute coronary syndromes without ST-segment elevation. N Engl J Med 2001; 345(7): 494-502.
    • (2001) N Engl J Med , vol.345 , Issue.7 , pp. 494-502
    • Yusuf, S.1    Zhao, F.2    Mehta, S.R.3    Chrolavicius, S.4    Tognoni, G.5    Fox, K.K.6
  • 18
    • 73149119363 scopus 로고    scopus 로고
    • Identification of the human cytochrome P450 enzymes involved in the two oxidative steps in the bioactivation of clopidogrel to its pharmacologically active metabolite
    • Kazui M, Nishiya Y, Ishizuka T, et al. Identification of the human cytochrome P450 enzymes involved in the two oxidative steps in the bioactivation of clopidogrel to its pharmacologically active metabolite. Drug Metab Dispos 2010; 38(1): 92-9.
    • (2010) Drug Metab Dispos , vol.38 , Issue.1 , pp. 92-99
    • Kazui, M.1    Nishiya, Y.2    Ishizuka, T.3
  • 19
    • 84870011593 scopus 로고    scopus 로고
    • The antiplatelet journey thus far: Focus on new oral P2Y12 inhibitors
    • Jan 9, 10.5083/ejcm.20424884.62
    • Wurtz M, Grove EL, Kristensen SD. The antiplatelet journey thus far: Focus on new oral P2Y12 inhibitors. Eur J Cardiovasc Med 2012 Jan 9;2(1):10.5083/ejcm.20424884.62.
    • (2012) Eur J Cardiovasc Med , vol.2 , Issue.1
    • Wurtz, M.1    Grove, E.L.2    Kristensen, S.D.3
  • 20
    • 61549124132 scopus 로고    scopus 로고
    • Risk of adverse outcomes associated with concomitant use of clopidogrel and proton pump inhibitors following acute coronary syndrome
    • Ho PM, Maddox TM, Wang L, et al. Risk of adverse outcomes associated with concomitant use of clopidogrel and proton pump inhibitors following acute coronary syndrome. JAMA 2009; 301(9): 937-44.
    • (2009) JAMA , vol.301 , Issue.9 , pp. 937-944
    • Ho, P.M.1    Maddox, T.M.2    Wang, L.3
  • 22
    • 58749094444 scopus 로고    scopus 로고
    • Cytochrome p-450 polymorphisms and response to clopidogrel
    • Mega JL, Close SL, Wiviott SD, et al. Cytochrome p-450 polymorphisms and response to clopidogrel. N Engl J Med 2009; 360(4): 354-62.
    • (2009) N Engl J Med , vol.360 , Issue.4 , pp. 354-362
    • Mega, J.L.1    Close, S.L.2    Wiviott, S.D.3
  • 23
    • 33845451677 scopus 로고    scopus 로고
    • A comparison of prasugrel and clopidogrel loading doses on platelet function: Magnitude of platelet inhibition is related to active metabolite formation
    • Brandt JT, Payne CD, Wiviott SD, et al. A comparison of prasugrel and clopidogrel loading doses on platelet function: magnitude of platelet inhibition is related to active metabolite formation. Am Heart J 2007; 153(1): 66-16.
    • (2007) Am Heart J , vol.153 , Issue.1 , pp. 16-66
    • Brandt, J.T.1    Payne, C.D.2    Wiviott, S.D.3
  • 24
    • 79960189314 scopus 로고    scopus 로고
    • The effect of ticagrelor versus clopidogrel on high on-treatment platelet reactivity: Combined analysis of the ONSET/OFFSET and RESPOND studies
    • Bliden KP, Tantry US, Storey RF, et al. The effect of ticagrelor versus clopidogrel on high on-treatment platelet reactivity: Combined analysis of the ONSET/OFFSET and RESPOND studies. Am Heart J 2011; 162(1): 160-5.
    • (2011) Am Heart J , vol.162 , Issue.1 , pp. 160-165
    • Bliden, K.P.1    Tantry, U.S.2    Storey, R.F.3
  • 25
    • 36148983750 scopus 로고    scopus 로고
    • Prasugrel versus clopidogrel in patients with acute coronary syndromes
    • Wiviott SD, Braunwald E, McCabe CH, et al. Prasugrel versus clopidogrel in patients with acute coronary syndromes. N Engl J Med 2007; 357(20): 2001-15.
    • (2007) N Engl J Med , vol.357 , Issue.20 , pp. 2001-2015
    • Wiviott, S.D.1    Braunwald, E.2    McCabe, C.H.3
  • 26
    • 70149101223 scopus 로고    scopus 로고
    • Ticagrelor versus clopidogrel in patients with acute coronary syndromes
    • Wallentin L, Becker RC, Budaj A, et al. Ticagrelor versus clopidogrel in patients with acute coronary syndromes. N Engl J Med 2009; 361(11): 1045-57.
    • (2009) N Engl J Med , vol.361 , Issue.11 , pp. 1045-1057
    • Wallentin, L.1    Becker, R.C.2    Budaj, A.3
  • 27
    • 77950508416 scopus 로고    scopus 로고
    • Response to ticagrelor in clopidogrel nonresponders and responders and effect of switching therapies: The RESPOND study
    • Mar 16
    • Gurbel PA, Bliden KP, Butler K, et al. Response to ticagrelor in clopidogrel nonresponders and responders and effect of switching therapies: the RESPOND study. Circulation 2010 Mar 16; 121(10): 1188-99.
    • (2010) Circulation , vol.121 , Issue.10 , pp. 1188-1199
    • Gurbel, P.A.1    Bliden, K.P.2    Butler, K.3
  • 28
    • 80053630737 scopus 로고    scopus 로고
    • Prasugrel overcomes high on-clopidogrel platelet reactivity in chronic coronary artery disease patients more effectively than high dose (150 mg) clopidogrel
    • Alexopoulos D, Xanthopoulou I, Davlouros P, et al. Prasugrel overcomes high on-clopidogrel platelet reactivity in chronic coronary artery disease patients more effectively than high dose (150 mg) clopidogrel. Am Heart J; 162(4): 733-9.
    • Am Heart J , vol.162 , Issue.4 , pp. 733-739
    • Alexopoulos, D.1    Xanthopoulou, I.2    Davlouros, P.3
  • 29
    • 53549085739 scopus 로고    scopus 로고
    • Platelet function testing in atherothrombotic disease: Steps forward in managing resistance to antiplatelet therapy
    • Grove EL, Hvas AM, Kristensen SD. Platelet function testing in atherothrombotic disease: steps forward in managing resistance to antiplatelet therapy. Kardiol Pol 2008; 66(4): 478-9.
    • (2008) Kardiol Pol , vol.66 , Issue.4 , pp. 478-479
    • Grove, E.L.1    Hvas, A.M.2    Kristensen, S.D.3
  • 30
    • 34447576539 scopus 로고    scopus 로고
    • Clopidogrel nonresponsiveness in patients undergoing percutaneous coronary intervention with stenting: A systematic review and meta-analysis
    • Snoep JD, Hovens MM, Eikenboom JC, van der Bom JG, Jukema JW, Huisman MV. Clopidogrel nonresponsiveness in patients undergoing percutaneous coronary intervention with stenting: a systematic review and meta-analysis. Am Heart J 2007; 154(2): 221-31.
    • (2007) Am Heart J , vol.154 , Issue.2 , pp. 221-231
    • Snoep, J.D.1    Hovens, M.M.2    Eikenboom, J.C.3    van der Bom, J.G.4    Jukema, J.W.5    Huisman, M.V.6
  • 31
    • 34447503098 scopus 로고    scopus 로고
    • Association of laboratory-defined aspirin resistance with a higher risk of recurrent cardiovascular events: A systematic review and meta-analysis
    • Snoep JD, Hovens MM, Eikenboom JC, van der Bom JG, Huisman MV. Association of laboratory-defined aspirin resistance with a higher risk of recurrent cardiovascular events: a systematic review and meta-analysis. Arch Intern Med 2007; 167(15): 1593-9.
    • (2007) Arch Intern Med , vol.167 , Issue.15 , pp. 1593-1599
    • Snoep, J.D.1    Hovens, M.M.2    Eikenboom, J.C.3    van der Bom, J.G.4    Huisman, M.V.5
  • 32
    • 67149093849 scopus 로고    scopus 로고
    • A shear gradientdependent platelet aggregation mechanism drives thrombus formation
    • Nesbitt WS, Westein E, Tovar-Lopez FJ, et al. A shear gradientdependent platelet aggregation mechanism drives thrombus formation. Nat Med 2009; 15(6): 665-73.
    • (2009) Nat Med , vol.15 , Issue.6 , pp. 665-673
    • Nesbitt, W.S.1    Westein, E.2    Tovar-Lopez, F.J.3
  • 33
    • 0027970934 scopus 로고
    • Development of aspirin resistance in persons with previous ischemic stroke
    • Helgason CM, Bolin KM, Hoff JA, et al. Development of aspirin resistance in persons with previous ischemic stroke. Stroke 1994; 25(12): 2331-6.
    • (1994) Stroke , vol.25 , Issue.12 , pp. 2331-2336
    • Helgason, C.M.1    Bolin, K.M.2    Hoff, J.A.3
  • 34
    • 0027279350 scopus 로고
    • Two-year followup of aspirin responder and aspirin non responder. A pilot-study including 180 post-stroke patients
    • Grotemeyer KH, Scharafinski HW, Husstedt IW. Two-year followup of aspirin responder and aspirin non responder. A pilot-study including 180 post-stroke patients. Thromb Res 1993; 71(5): 397-403.
    • (1993) Thromb Res , vol.71 , Issue.5 , pp. 397-403
    • Grotemeyer, K.H.1    Scharafinski, H.W.2    Husstedt, I.W.3
  • 35
    • 0036379817 scopus 로고    scopus 로고
    • Individual variations of platelet inhibition after loading doses of clopidogrel
    • Jaremo P, Lindahl TL, Fransson SG, Richter A. Individual variations of platelet inhibition after loading doses of clopidogrel. J Intern Med 2002; 252(3): 233-8.
    • (2002) J Intern Med , vol.252 , Issue.3 , pp. 233-238
    • Jaremo, P.1    Lindahl, T.L.2    Fransson, S.G.3    Richter, A.4
  • 36
    • 0038649988 scopus 로고    scopus 로고
    • Clopidogrel for coronary stenting: Response variability, drug resistance, and the effect of pretreatment platelet reactivity
    • Gurbel PA, Bliden KP, Hiatt BL, O'Connor CM. Clopidogrel for coronary stenting: response variability, drug resistance, and the effect of pretreatment platelet reactivity. Circulation 2003; 107(23): 2908-13.
    • (2003) Circulation , vol.107 , Issue.23 , pp. 2908-2913
    • Gurbel, P.A.1    Bliden, K.P.2    Hiatt, B.L.3    O'Connor, C.M.4
  • 37
    • 8344221349 scopus 로고    scopus 로고
    • Clopidogrel resistance is associated with increased risk of recurrent atherothrombotic events in patients with acute myocardial infarction
    • Matetzky S, Shenkman B, Guetta V, et al. Clopidogrel resistance is associated with increased risk of recurrent atherothrombotic events in patients with acute myocardial infarction. Circulation 2004; 109(25): 3171-5.
    • (2004) Circulation , vol.109 , Issue.25 , pp. 3171-3175
    • Matetzky, S.1    Shenkman, B.2    Guetta, V.3
  • 38
    • 33749503499 scopus 로고    scopus 로고
    • Low response to clopidogrel is associated with cardiovascular outcome after coronary stent implantation
    • Geisler T, Langer H, Wydymus M, et al. Low response to clopidogrel is associated with cardiovascular outcome after coronary stent implantation. Eur Heart J 2006; 27(20): 2420-5.
    • (2006) Eur Heart J , vol.27 , Issue.20 , pp. 2420-2425
    • Geisler, T.1    Langer, H.2    Wydymus, M.3
  • 39
    • 33750479499 scopus 로고    scopus 로고
    • Impact of the degree of peri-interventional platelet inhibition after loading with clopidogrel on early clinical outcome of elective coronary stent placement
    • Hochholzer W, Trenk D, Bestehorn HP, et al. Impact of the degree of peri-interventional platelet inhibition after loading with clopidogrel on early clinical outcome of elective coronary stent placement. J Am Coll Cardiol 2006; 48(9): 1742-50.
    • (2006) J Am Coll Cardiol , vol.48 , Issue.9 , pp. 1742-1750
    • Hochholzer, W.1    Trenk, D.2    Bestehorn, H.P.3
  • 40
    • 33748948717 scopus 로고    scopus 로고
    • Benefit of a 600-mg loading dose of clopidogrel on platelet reactivity and clinical outcomes in patients with non-ST-segment elevation acute coronary syndrome undergoing coronary stenting
    • Cuisset T, Frere C, Quilici J, et al. Benefit of a 600-mg loading dose of clopidogrel on platelet reactivity and clinical outcomes in patients with non-ST-segment elevation acute coronary syndrome undergoing coronary stenting. J Am Coll Cardiol 2006; 48(7): 1339-45.
    • (2006) J Am Coll Cardiol , vol.48 , Issue.7 , pp. 1339-1345
    • Cuisset, T.1    Frere, C.2    Quilici, J.3
  • 41
    • 51649108832 scopus 로고    scopus 로고
    • Point-of-care measurement of clopidogrel responsiveness predicts clinical outcome in patients undergoing percutaneous coronary intervention results of the ARMYDA-PRO (Antiplatelet therapy for Reduction of MYocardial Damage during Angioplasty-Platelet Reactivity Predicts Outcome) study
    • Patti G, Nusca A, Mangiacapra F, Gatto L, D'Ambrosio A, Di SG. Point-of-care measurement of clopidogrel responsiveness predicts clinical outcome in patients undergoing percutaneous coronary intervention results of the ARMYDA-PRO (Antiplatelet therapy for Reduction of MYocardial Damage during Angioplasty-Platelet Reactivity Predicts Outcome) study. J Am Coll Cardiol 2008; 52(14): 1128-33.
    • (2008) J Am Coll Cardiol , vol.52 , Issue.14 , pp. 1128-1133
    • Patti, G.1    Nusca, A.2    Mangiacapra, F.3    Gatto, L.4    D'Ambrosio, A.5    Di, S.G.6
  • 42
    • 59849120163 scopus 로고    scopus 로고
    • Cardiovascular death and nonfatal myocardial infarction in acute coronary syndrome patients receiving coronary stenting are predicted by residual platelet reactivity to ADP detected by a point-of-care assay: A 12-month followup
    • Marcucci R, Gori AM, Paniccia R, et al. Cardiovascular death and nonfatal myocardial infarction in acute coronary syndrome patients receiving coronary stenting are predicted by residual platelet reactivity to ADP detected by a point-of-care assay: a 12-month followup. Circulation 2009; 119(2): 237-42.
    • (2009) Circulation , vol.119 , Issue.2 , pp. 237-242
    • Marcucci, R.1    Gori, A.M.2    Paniccia, R.3
  • 43
    • 77249113768 scopus 로고    scopus 로고
    • Comparison of platelet function tests in predicting clinical outcome in patients undergoing coronary stent implantation
    • Breet NJ, van Werkum JW, Bouman HJ, et al. Comparison of platelet function tests in predicting clinical outcome in patients undergoing coronary stent implantation. JAMA 2010; 303(8): 754-62.
    • (2010) JAMA , vol.303 , Issue.8 , pp. 754-762
    • Breet, N.J.1    van Werkum, J.W.2    Bouman, H.J.3
  • 44
    • 77958012405 scopus 로고    scopus 로고
    • Long-term clinical outcome based on aspirin and clopidogrel responsiveness status after elective percutaneous coronary intervention: A 3T/2R (tailoring treatment with tirofiban in patients showing resistance to aspirin and/or resistance to clopidogrel) trial substudy
    • Campo G, Fileti L, de CN, et al. Long-term clinical outcome based on aspirin and clopidogrel responsiveness status after elective percutaneous coronary intervention: a 3T/2R (tailoring treatment with tirofiban in patients showing resistance to aspirin and/or resistance to clopidogrel) trial substudy. J Am Coll Cardiol 2010; 56(18): 1447-55.
    • (2010) J Am Coll Cardiol , vol.56 , Issue.18 , pp. 1447-1455
    • Campo, G.1    Fileti, L.2    De, C.N.3
  • 45
    • 80053080512 scopus 로고    scopus 로고
    • High residual platelet reactivity after clopidogrel loading and long-term cardiovascular events among patients with acute coronary syndromes undergoing PCI
    • Parodi G, Marcucci R, Valenti R, et al. High residual platelet reactivity after clopidogrel loading and long-term cardiovascular events among patients with acute coronary syndromes undergoing PCI. JAMA 2011; 306(11): 1215-23.
    • (2011) JAMA , vol.306 , Issue.11 , pp. 1215-1223
    • Parodi, G.1    Marcucci, R.2    Valenti, R.3
  • 46
    • 80052573217 scopus 로고    scopus 로고
    • Platelet Reactivity and Cardiovascular Outcomes After Percutaneous Coronary Intervention: A Time-Dependent Analysis of the Gauging Responsiveness With a VerifyNow P2Y12 Assay: Impact on Thrombosis and Safety (GRAVITAS) Trial
    • Price MJ, Angiolillo DJ, Teirstein PS, et al. Platelet Reactivity and Cardiovascular Outcomes After Percutaneous Coronary Intervention: A Time-Dependent Analysis of the Gauging Responsiveness With a VerifyNow P2Y12 Assay: Impact on Thrombosis and Safety (GRAVITAS) Trial. Circulation 2011; 124(10): 1132-7.
    • (2011) Circulation , vol.124 , Issue.10 , pp. 1132-1137
    • Price, M.J.1    Angiolillo, D.J.2    Teirstein, P.S.3
  • 47
    • 80052167250 scopus 로고    scopus 로고
    • Impact of platelet reactivity on clinical outcomes after percutaneous coronary intervention a collaborative meta-analysis of individual participant data
    • Brar SS, ten BJ, Marcucci R, et al. Impact of platelet reactivity on clinical outcomes after percutaneous coronary intervention a collaborative meta-analysis of individual participant data. J Am Coll Cardiol 2011; 58(19): 1945-54.
    • (2011) J Am Coll Cardiol , vol.58 , Issue.19 , pp. 1945-1954
    • Brar, S.S.1    Ten, B.J.2    Marcucci, R.3
  • 48
    • 32844458145 scopus 로고    scopus 로고
    • Aspirin resistance
    • Hankey GJ, Eikelboom JW. Aspirin resistance. Lancet 2006; 367(9510): 606-17.
    • (2006) Lancet , vol.367 , Issue.9510 , pp. 606-617
    • Hankey, G.J.1    Eikelboom, J.W.2
  • 50
    • 0031789272 scopus 로고    scopus 로고
    • The global burden of disease, 1990-2020
    • Lopez AD, Murray CC. The global burden of disease, 1990-2020. Nat Med 1998; 4(11): 1241-3.
    • (1998) Nat Med , vol.4 , Issue.11 , pp. 1241-1243
    • Lopez, A.D.1    Murray, C.C.2
  • 51
    • 77957261811 scopus 로고    scopus 로고
    • Background, incidence, and predictors of antiplatelet therapy discontinuation during the first year after drug-eluting stent implantation
    • Ferreira-Gonzalez I, Marsal JR, Ribera A, et al. Background, incidence, and predictors of antiplatelet therapy discontinuation during the first year after drug-eluting stent implantation. Circulation 2010; 122(10): 1017-25.
    • (2010) Circulation , vol.122 , Issue.10 , pp. 1017-1025
    • Ferreira-Gonzalez, I.1    Marsal, J.R.2    Ribera, A.3
  • 52
    • 23044442340 scopus 로고    scopus 로고
    • Adherence to medication
    • Osterberg L, Blaschke T. Adherence to medication. N Engl J Med 2005; 353(5): 487-97.
    • (2005) N Engl J Med , vol.353 , Issue.5 , pp. 487-497
    • Osterberg, L.1    Blaschke, T.2
  • 54
    • 16844362580 scopus 로고    scopus 로고
    • Compliance as a critical consideration in patients who appear to be resistant to aspirin after healing of myocardial infarction
    • Schwartz KA, Schwartz DE, Ghosheh K, Reeves MJ, Barber K, DeFranco A. Compliance as a critical consideration in patients who appear to be resistant to aspirin after healing of myocardial infarction. Am J Cardiol 2005; 95(8): 973-5.
    • (2005) Am J Cardiol , vol.95 , Issue.8 , pp. 973-975
    • Schwartz, K.A.1    Schwartz, D.E.2    Ghosheh, K.3    Reeves, M.J.4    Barber, K.5    Defranco, A.6
  • 55
    • 52049106554 scopus 로고    scopus 로고
    • Non-compliance is the predominant cause of aspirin resistance in chronic coronary arterial disease patients
    • Schwartz KA, Schwartz DE, Barber K, Reeves M, De Franco AC. Non-compliance is the predominant cause of aspirin resistance in chronic coronary arterial disease patients. J Transl Med 2008; 6: 46.
    • (2008) J Transl Med , vol.6 , pp. 46
    • Schwartz, K.A.1    Schwartz, D.E.2    Barber, K.3    Reeves, M.4    de Franco, A.C.5
  • 56
    • 10744228434 scopus 로고    scopus 로고
    • Lack of aspirin effect: Aspirin resistance or resistance to taking aspirin?
    • Cotter G, Shemesh E, Zehavi M, et al. Lack of aspirin effect: aspirin resistance or resistance to taking aspirin? Am Heart J 2004; 147(2): 293-300.
    • (2004) Am Heart J , vol.147 , Issue.2 , pp. 293-300
    • Cotter, G.1    Shemesh, E.2    Zehavi, M.3
  • 57
    • 33750924102 scopus 로고    scopus 로고
    • A systematic review and meta-analysis on the hazards of discontinuing or not adhering to aspirin among 50,279 patients at risk for coronary artery disease
    • Biondi-Zoccai GG, Lotrionte M, Agostoni P, et al. A systematic review and meta-analysis on the hazards of discontinuing or not adhering to aspirin among 50,279 patients at risk for coronary artery disease. Eur Heart J 2006; 27(22): 2667-74.
    • (2006) Eur Heart J , vol.27 , Issue.22 , pp. 2667-2674
    • Biondi-Zoccai, G.G.1    Lotrionte, M.2    Agostoni, P.3
  • 58
    • 33749003498 scopus 로고    scopus 로고
    • Impact of medication therapy discontinuation on mortality after myocardial infarction
    • Ho PM, Spertus JA, Masoudi FA, et al. Impact of medication therapy discontinuation on mortality after myocardial infarction. Arch Intern Med 2006; 166(17): 1842-7.
    • (2006) Arch Intern Med , vol.166 , Issue.17 , pp. 1842-1847
    • Ho, P.M.1    Spertus, J.A.2    Masoudi, F.A.3
  • 59
    • 27144482754 scopus 로고    scopus 로고
    • Effect of compliance and dosage adaptation of long term aspirin on platelet function with PFA-100 in patients after myocardial infarction
    • von Pape KW, Strupp G, Bonzel T, Bohner J. Effect of compliance and dosage adaptation of long term aspirin on platelet function with PFA-100 in patients after myocardial infarction. Thromb Haemost 2005; 94(4): 889-91.
    • (2005) Thromb Haemost , vol.94 , Issue.4 , pp. 889-891
    • von Pape, K.W.1    Strupp, G.2    Bonzel, T.3    Bohner, J.4
  • 60
    • 0037261957 scopus 로고    scopus 로고
    • Adherence to secondary stroke prevention strategies--results from the German Stroke Data Bank
    • Hamann GF, Weimar C, Glahn J, Busse O, Diener HC. Adherence to secondary stroke prevention strategies--results from the German Stroke Data Bank. Cerebrovasc Dis 2003; 15(4): 282-8.
    • (2003) Cerebrovasc Dis , vol.15 , Issue.4 , pp. 282-288
    • Hamann, G.F.1    Weimar, C.2    Glahn, J.3    Busse, O.4    Diener, H.C.5
  • 61
    • 33745960402 scopus 로고    scopus 로고
    • Prevalence, predictors, and outcomes of premature discontinuation of thienopyridine therapy after drug-eluting stent placement: Results from the PREMIER registry
    • Spertus JA, Kettelkamp R, Vance C, et al. Prevalence, predictors, and outcomes of premature discontinuation of thienopyridine therapy after drug-eluting stent placement: results from the PREMIER registry. Circulation 2006; 113(24): 2803-9.
    • (2006) Circulation , vol.113 , Issue.24 , pp. 2803-2809
    • Spertus, J.A.1    Kettelkamp, R.2    Vance, C.3
  • 62
    • 70549107994 scopus 로고    scopus 로고
    • Association of platelet responsiveness with clopidogrel metabolism: Role of compliance in the assessment of resistance
    • Serebruany V, Cherala G, Williams C, et al. Association of platelet responsiveness with clopidogrel metabolism: role of compliance in the assessment of resistance. Am Heart J 2009; 158(6): 925-32.
    • (2009) Am Heart J , vol.158 , Issue.6 , pp. 925-932
    • Serebruany, V.1    Cherala, G.2    Williams, C.3
  • 63
    • 79951579337 scopus 로고    scopus 로고
    • Identifying patients at risk for premature discontinuation of thienopyridine after coronary stent implantation
    • Quadros AS, Welter DI, Camozzatto FO, et al. Identifying patients at risk for premature discontinuation of thienopyridine after coronary stent implantation. Am J Cardiol 2011; 107(5): 685-9.
    • (2011) Am J Cardiol , vol.107 , Issue.5 , pp. 685-689
    • Quadros, A.S.1    Welter, D.I.2    Camozzatto, F.O.3
  • 64
    • 80052026195 scopus 로고    scopus 로고
    • Low doses of acetylsalicylic Acid increase risk of gastrointestinal bleeding in a meta-analysis
    • Lanas A, Wu P, Medin J, Mills EJ. Low doses of acetylsalicylic Acid increase risk of gastrointestinal bleeding in a meta-analysis. Clin Gastroenterol Hepatol 2011; 9(9): 762-8.
    • (2011) Clin Gastroenterol Hepatol , vol.9 , Issue.9 , pp. 762-768
    • Lanas, A.1    Wu, P.2    Medin, J.3    Mills, E.J.4
  • 65
    • 12144275353 scopus 로고    scopus 로고
    • Clopidogrel versus aspirin and esomeprazole to prevent recurrent ulcer bleeding
    • Chan FK, Ching JY, Hung LC, et al. Clopidogrel versus aspirin and esomeprazole to prevent recurrent ulcer bleeding. N Engl J Med 2005; 352(3): 238-44.
    • (2005) N Engl J Med , vol.352 , Issue.3 , pp. 238-244
    • Chan, F.K.1    Ching, J.Y.2    Hung, L.C.3
  • 66
    • 79953043171 scopus 로고    scopus 로고
    • Risk of upper gastrointestinal bleeding with low-dose acetylsalicylic acid alone and in combination with clopidogrel and other medications
    • Garcia Rodriguez LA, Lin KJ, Hernandez-Diaz S, Johansson S. Risk of upper gastrointestinal bleeding with low-dose acetylsalicylic acid alone and in combination with clopidogrel and other medications. Circulation 2011; 123(10): 1108-15.
    • (2011) Circulation , vol.123 , Issue.10 , pp. 1108-1115
    • Garcia Rodriguez, L.A.1    Lin, K.J.2    Hernandez-Diaz, S.3    Johansson, S.4
  • 67
    • 78149487926 scopus 로고    scopus 로고
    • Clopidogrel with or without omeprazole in coronary artery disease
    • Bhatt DL, Cryer BL, Contant CF, et al. Clopidogrel with or without omeprazole in coronary artery disease. N Engl J Med 2010; 363(20): 1909-17.
    • (2010) N Engl J Med , vol.363 , Issue.20 , pp. 1909-1917
    • Bhatt, D.L.1    Cryer, B.L.2    Contant, C.F.3
  • 68
    • 77649210337 scopus 로고    scopus 로고
    • The antiplatelet effect of aspirin is reduced by proton pump inhibitors in patients with coronary artery disease
    • Wurtz M, Grove EL, Kristensen SD, Hvas AM. The antiplatelet effect of aspirin is reduced by proton pump inhibitors in patients with coronary artery disease. Heart 2010; 96(5): 368-71.
    • (2010) Heart , vol.96 , Issue.5 , pp. 368-371
    • Wurtz, M.1    Grove, E.L.2    Kristensen, S.D.3    Hvas, A.M.4
  • 69
    • 79956336197 scopus 로고    scopus 로고
    • Proton pump inhibitor use and risk of adverse cardiovascular events in aspirin treated patients with first time myocardial infarction: Nationwide propensity score matched study
    • Charlot M, Grove EL, Hansen PR, et al. Proton pump inhibitor use and risk of adverse cardiovascular events in aspirin treated patients with first time myocardial infarction: nationwide propensity score matched study. BMJ 2011; 342: d2690.
    • (2011) BMJ , vol.342
    • Charlot, M.1    Grove, E.L.2    Hansen, P.R.3
  • 70
    • 27744581956 scopus 로고    scopus 로고
    • Platelet response to lowdose enteric-coated aspirin in patients with stable cardiovascular disease
    • Maree AO, Curtin RJ, Dooley M, et al. Platelet response to lowdose enteric-coated aspirin in patients with stable cardiovascular disease. J Am Coll Cardiol 2005; 46(7): 1258-63.
    • (2005) J Am Coll Cardiol , vol.46 , Issue.7 , pp. 1258-1263
    • Maree, A.O.1    Curtin, R.J.2    Dooley, M.3
  • 71
    • 33747168513 scopus 로고    scopus 로고
    • Effect of enteric coating on antiplatelet activity of low-dose aspirin in healthy volunteers
    • Cox D, Maree AO, Dooley M, Conroy R, Byrne MF, Fitzgerald DJ. Effect of enteric coating on antiplatelet activity of low-dose aspirin in healthy volunteers. Stroke 2006; 37(8): 2153-8.
    • (2006) Stroke , vol.37 , Issue.8 , pp. 2153-2158
    • Cox, D.1    Maree, A.O.2    Dooley, M.3    Conroy, R.4    Byrne, M.F.5    Fitzgerald, D.J.6
  • 72
    • 68149180722 scopus 로고    scopus 로고
    • Recent developments in clopidogrel pharmacology and their relation to clinical outcomes
    • Gurbel PA, Antonino MJ, Tantry US. Recent developments in clopidogrel pharmacology and their relation to clinical outcomes. Expert Opin Drug Metab Toxicol 2009; 5(8): 989-1004.
    • (2009) Expert Opin Drug Metab Toxicol , vol.5 , Issue.8 , pp. 989-1004
    • Gurbel, P.A.1    Antonino, M.J.2    Tantry, U.S.3
  • 73
    • 33751080762 scopus 로고    scopus 로고
    • Impact of P-glycoprotein on clopidogrel absorption
    • Taubert D, von BN, Grimberg G, et al. Impact of P-glycoprotein on clopidogrel absorption. Clin Pharmacol Ther 2006; 80(5): 486-501.
    • (2006) Clin Pharmacol Ther , vol.80 , Issue.5 , pp. 486-501
    • Taubert, D.1    von, B.N.2    Grimberg, G.3
  • 74
    • 58749090547 scopus 로고    scopus 로고
    • Genetic determinants of response to clopidogrel and cardiovascular events
    • Simon T, Verstuyft C, Mary-Krause M, et al. Genetic determinants of response to clopidogrel and cardiovascular events. N Engl J Med 2009; 360(4): 363-75.
    • (2009) N Engl J Med , vol.360 , Issue.4 , pp. 363-375
    • Simon, T.1    Verstuyft, C.2    Mary-Krause, M.3
  • 75
    • 46049108934 scopus 로고    scopus 로고
    • Antiplatelet drugs: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines (8th Edition)
    • Patrono C, Baigent C, Hirsh J, Roth G. Antiplatelet drugs: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines (8th Edition). Chest 2008; 133(6 Suppl): 199S-233S.
    • (2008) Chest , vol.133 , Issue.6 SUPPL.
    • Patrono, C.1    Baigent, C.2    Hirsh, J.3    Roth, G.4
  • 76
    • 84856158305 scopus 로고    scopus 로고
    • ESC Guidelines for the management of acute coronary syndromes in patients presenting without persistent ST-segment elevation: The Task Force for the management of acute coronary syndromes (ACS) in patients presenting without persistent ST-segment elevation of the European Society of Cardiology (ESC)
    • Hamm CW, Bassand JP, Agewall S, et al. ESC Guidelines for the management of acute coronary syndromes in patients presenting without persistent ST-segment elevation: The Task Force for the management of acute coronary syndromes (ACS) in patients presenting without persistent ST-segment elevation of the European Society of Cardiology (ESC). Eur Heart J 2011; 32(23): 2999-3054.
    • (2011) Eur Heart J , vol.32 , Issue.23 , pp. 2999-3054
    • Hamm, C.W.1    Bassand, J.P.2    Agewall, S.3
  • 77
    • 77958005516 scopus 로고    scopus 로고
    • Double-dose versus standard-dose clopidogrel and high-dose versus low-dose aspirin in individuals undergoing percutaneous coronary intervention for acute coronary syndromes (CURRENT-OASIS 7): A randomised factorial trial
    • Mehta SR, Tanguay JF, Eikelboom JW, et al. Double-dose versus standard-dose clopidogrel and high-dose versus low-dose aspirin in individuals undergoing percutaneous coronary intervention for acute coronary syndromes (CURRENT-OASIS 7): a randomised factorial trial. Lancet 2010; 376(9748): 1233-43.
    • (2010) Lancet , vol.376 , Issue.9748 , pp. 1233-1243
    • Mehta, S.R.1    Tanguay, J.F.2    Eikelboom, J.W.3
  • 79
    • 77956290748 scopus 로고    scopus 로고
    • Dose comparisons of clopidogrel and aspirin in acute coronary syndromes
    • Mehta SR, Bassand JP, Chrolavicius S, et al. Dose comparisons of clopidogrel and aspirin in acute coronary syndromes. N Engl J Med 2010; 363(10): 930-42.
    • (2010) N Engl J Med , vol.363 , Issue.10 , pp. 930-942
    • Mehta, S.R.1    Bassand, J.P.2    Chrolavicius, S.3
  • 80
    • 38949119325 scopus 로고    scopus 로고
    • Aspirin resistance and risk of cardiovascular morbidity: Systematic review and meta-analysis
    • Krasopoulos G, Brister SJ, Beattie WS, Buchanan MR. Aspirin resistance and risk of cardiovascular morbidity: systematic review and meta-analysis. BMJ 2008; 336(7637): 195-8.
    • (2008) BMJ , vol.336 , Issue.7637 , pp. 195-198
    • Krasopoulos, G.1    Brister, S.J.2    Beattie, W.S.3    Buchanan, M.R.4
  • 81
    • 79953657561 scopus 로고    scopus 로고
    • Aspirin resistance: Effect of clinical, biochemical and genetic factors
    • Fitzgerald R, Pirmohamed M. Aspirin resistance: Effect of clinical, biochemical and genetic factors. Pharmacol Ther 2011; 130(2): 213-25.
    • (2011) Pharmacol Ther , vol.130 , Issue.2 , pp. 213-225
    • Fitzgerald, R.1    Pirmohamed, M.2
  • 82
    • 0021163545 scopus 로고
    • Dose-related kinetics of aspirin. Presystemic acetylation of platelet cyclooxygenase
    • Pedersen AK, Fitz-Gerald GA. Dose-related kinetics of aspirin. Presystemic acetylation of platelet cyclooxygenase. N Engl J Med 1984; 311(19): 1206-11.
    • (1984) N Engl J Med , vol.311 , Issue.19 , pp. 1206-1211
    • Pedersen, A.K.1    Fitz-Gerald, G.A.2
  • 83
    • 0022396676 scopus 로고
    • Clinical pharmacology of platelet cyclooxygenase inhibition
    • Patrono C, Ciabattoni G, Patrignani P, et al. Clinical pharmacology of platelet cyclooxygenase inhibition. Circulation 1985; 72(6): 1177-84.
    • (1985) Circulation , vol.72 , Issue.6 , pp. 1177-1184
    • Patrono, C.1    Ciabattoni, G.2    Patrignani, P.3
  • 84
    • 12144290822 scopus 로고    scopus 로고
    • Aspirin dose and sixmonth outcome after an acute coronary syndrome
    • Quinn MJ, Aronow HD, Califf RM, et al. Aspirin dose and sixmonth outcome after an acute coronary syndrome. J Am Coll Cardiol 2004; 43(6): 972-8.
    • (2004) J Am Coll Cardiol , vol.43 , Issue.6 , pp. 972-978
    • Quinn, M.J.1    Aronow, H.D.2    Califf, R.M.3
  • 85
    • 79851495676 scopus 로고    scopus 로고
    • 24-hour time-dependent aspirin efficacy in patients with stable coronary artery disease
    • Henry P, Vermillet A, Boval B, et al. 24-hour time-dependent aspirin efficacy in patients with stable coronary artery disease. Thromb Haemost 2011; 105(2): 336-44.
    • (2011) Thromb Haemost , vol.105 , Issue.2 , pp. 336-344
    • Henry, P.1    Vermillet, A.2    Boval, B.3
  • 86
    • 79959318812 scopus 로고    scopus 로고
    • Pharmacodynamic Effects of Different Aspirin Dosing Regimens in Type 2 Diabetes Mellitus Patients With Coronary Artery Disease
    • Capodanno D, Patel A, Dharmashankar K, et al. Pharmacodynamic Effects of Different Aspirin Dosing Regimens in Type 2 Diabetes Mellitus Patients With Coronary Artery Disease. Circ Cardiovasc Interv 2011; 4(2): 180-7.
    • (2011) Circ Cardiovasc Interv , vol.4 , Issue.2 , pp. 180-187
    • Capodanno, D.1    Patel, A.2    Dharmashankar, K.3
  • 87
    • 80052306473 scopus 로고    scopus 로고
    • Twice daily dosing of aspirin improves platelet inhibition in whole blood in patients with type 2 diabetes mellitus and microor macrovascular complications
    • Spectre G, Arnetz L, Ostenson CG, Brismar K, Li N, Hjemdahl P. Twice daily dosing of aspirin improves platelet inhibition in whole blood in patients with type 2 diabetes mellitus and microor macrovascular complications. Thromb Haemost 2011; 106(3): 491-9.
    • (2011) Thromb Haemost , vol.106 , Issue.3 , pp. 491-499
    • Spectre, G.1    Arnetz, L.2    Ostenson, C.G.3    Brismar, K.4    Li, N.5    Hjemdahl, P.6
  • 88
    • 84655162752 scopus 로고    scopus 로고
    • Twice daily aspirin to improve biological aspirin efficacy in patients with essential thrombocytemia
    • Dillinger JG, Sideris G, Henry P, Bal Dit SC, Ronez E, Drouet L. Twice daily aspirin to improve biological aspirin efficacy in patients with essential thrombocytemia. Thromb Res 2012; 129(1): 91-4.
    • (2012) Thromb Res , vol.129 , Issue.1 , pp. 91-94
    • Dillinger, J.G.1    Sideris, G.2    Henry, P.3    Bal, D.S.C.4    Ronez, E.5    Drouet, L.6
  • 89
    • 78650952436 scopus 로고    scopus 로고
    • Effect of platelet turnover on whole blood platelet aggregation in patients with coronary artery disease
    • Grove EL, Hvas AM, Mortensen SB, Larsen SB, Kristensen SD. Effect of platelet turnover on whole blood platelet aggregation in patients with coronary artery disease. J Thromb Haemost 2011; 9(1): 185-91.
    • (2011) J Thromb Haemost , vol.9 , Issue.1 , pp. 185-191
    • Grove, E.L.1    Hvas, A.M.2    Mortensen, S.B.3    Larsen, S.B.4    Kristensen, S.D.5
  • 90
    • 77958128969 scopus 로고    scopus 로고
    • Guidelines on myocardial revascularization: The Task Force on Myocardial Revascularization of the European Society of Cardiology (ESC) and the European Association for Cardio-Thoracic Surgery (EACTS)
    • Wijns W, Kolh P, Danchin N, et al. Guidelines on myocardial revascularization: The Task Force on Myocardial Revascularization of the European Society of Cardiology (ESC) and the European Association for Cardio-Thoracic Surgery (EACTS). Eur Heart J 2010; 31(20): 2501-55.
    • (2010) Eur Heart J , vol.31 , Issue.20 , pp. 2501-2555
    • Wijns, W.1    Kolh, P.2    Danchin, N.3
  • 91
    • 34248397644 scopus 로고    scopus 로고
    • A double-blind, randomized study on platelet aggregation in patients treated with a daily dose of 150 or 75 mg of clopidogrel for 30 days
    • von BN, Kastrati A, Wieczorek A, et al. A double-blind, randomized study on platelet aggregation in patients treated with a daily dose of 150 or 75 mg of clopidogrel for 30 days. Eur Heart J 2007; 28(15): 1814-9.
    • (2007) Eur Heart J , vol.28 , Issue.15 , pp. 1814-1819
    • von, B.N.1    Kastrati, A.2    Wieczorek, A.3
  • 92
    • 41249093357 scopus 로고    scopus 로고
    • Adjusted clopidogrel loading doses according to vasodilator-stimulated phosphoprotein phosphorylation index decrease rate of major adverse cardiovascular events in patients with clopidogrel resistance: A multicenter randomized prospective study
    • Bonello L, Camoin-Jau L, Arques S, et al. Adjusted clopidogrel loading doses according to vasodilator-stimulated phosphoprotein phosphorylation index decrease rate of major adverse cardiovascular events in patients with clopidogrel resistance: a multicenter randomized prospective study. J Am Coll Cardiol 2008; 51(14): 1404-11.
    • (2008) J Am Coll Cardiol , vol.51 , Issue.14 , pp. 1404-1411
    • Bonello, L.1    Camoin-Jau, L.2    Arques, S.3
  • 93
    • 84855992555 scopus 로고    scopus 로고
    • ACCF/AHA/SCAI Guideline for Percutaneous Coronary Intervention. A report of the American College of Cardiology Foundation/American Heart Association Task Force on Pratice Guidelines and the Society for Cardiovascular Angiography and Interventions
    • Levine GN, Bates ER, Blankenship JC, et al. 2011 ACCF/AHA/SCAI Guideline for Percutaneous Coronary Intervention. A report of the American College of Cardiology Foundation/American Heart Association Task Force on Pratice Guidelines and the Society for Cardiovascular Angiography and Interventions. J Am Coll Cardiol 2011; 58(24): e44-122.
    • (2011) J Am Coll Cardiol , vol.58 , Issue.24 , pp. 44-122
    • Levine, G.N.1    Bates, E.R.2    Blankenship, J.C.3
  • 95
    • 33746218509 scopus 로고    scopus 로고
    • Platelet inhibition beyond conventional antiplatelet agents: Expanding role of angiotensin receptor blockers, statins and selective serotonin reuptake inhibitors
    • Malinin AI, Ong S, Makarov LM, Petukhova EY, Serebruany VL. Platelet inhibition beyond conventional antiplatelet agents: expanding role of angiotensin receptor blockers, statins and selective serotonin reuptake inhibitors. Int J Clin Pract 2006; 60(8): 993-1002.
    • (2006) Int J Clin Pract , vol.60 , Issue.8 , pp. 993-1002
    • Malinin, A.I.1    Ong, S.2    Makarov, L.M.3    Petukhova, E.Y.4    Serebruany, V.L.5
  • 96
    • 0041967519 scopus 로고    scopus 로고
    • Selective serotonin reuptake inhibitors yield additional antiplatelet protection in patients with congestive heart failure treated with antecedent aspirin
    • Serebruany VL, Glassman AH, Malinin AI, et al. Selective serotonin reuptake inhibitors yield additional antiplatelet protection in patients with congestive heart failure treated with antecedent aspirin. Eur J Heart Fail 2003; 5(4): 517-21.
    • (2003) Eur J Heart Fail , vol.5 , Issue.4 , pp. 517-521
    • Serebruany, V.L.1    Glassman, A.H.2    Malinin, A.I.3
  • 97
    • 0033805348 scopus 로고    scopus 로고
    • Evaluation of the effects of aspirin combined with angiotensin-converting enzyme inhibitors in patients with coronary artery disease
    • Peterson JG, Topol EJ, Sapp SK, Young JB, Lincoff AM, Lauer MS. Evaluation of the effects of aspirin combined with angiotensin-converting enzyme inhibitors in patients with coronary artery disease. Am J Med 2000; 109(5): 371-7.
    • (2000) Am J Med , vol.109 , Issue.5 , pp. 371-377
    • Peterson, J.G.1    Topol, E.J.2    Sapp, S.K.3    Young, J.B.4    Lincoff, A.M.5    Lauer, M.S.6
  • 98
    • 19444385004 scopus 로고    scopus 로고
    • Carvedilol--a beta-blocker with considerable antiaggregatory effect on human blood platelets
    • Petrikova M, Jancinova V, Nosal R, Majekova M, Fabryova V. Carvedilol--a beta-blocker with considerable antiaggregatory effect on human blood platelets. Bratisl Lek Listy 2005; 106(1): 20-5.
    • (2005) Bratisl Lek Listy , vol.106 , Issue.1 , pp. 20-25
    • Petrikova, M.1    Jancinova, V.2    Nosal, R.3    Majekova, M.4    Fabryova, V.5
  • 99
    • 33748190263 scopus 로고    scopus 로고
    • Aspirin resistance: Possible roles of cardiovascular risk factors, previous disease history, concomitant medications and haemorrheological variables
    • Feher G, Koltai K, Papp E, et al. Aspirin resistance: possible roles of cardiovascular risk factors, previous disease history, concomitant medications and haemorrheological variables. Drugs Aging 2006; 23(7): 559-67.
    • (2006) Drugs Aging , vol.23 , Issue.7 , pp. 559-567
    • Feher, G.1    Koltai, K.2    Papp, E.3
  • 100
    • 0035924765 scopus 로고    scopus 로고
    • Cyclooxygenase inhibitors and the antiplatelet effects of aspirin
    • Catella-Lawson F, Reilly MP, Kapoor SC, et al. Cyclooxygenase inhibitors and the antiplatelet effects of aspirin. N Engl J Med 2001; 345(25): 1809-17.
    • (2001) N Engl J Med , vol.345 , Issue.25 , pp. 1809-1817
    • Catella-Lawson, F.1    Reilly, M.P.2    Kapoor, S.C.3
  • 101
    • 0042416748 scopus 로고    scopus 로고
    • Inhibition of clinical benefits of aspirin on first myocardial infarction by nonsteroidal antiinflammatory drugs
    • Kurth T, Glynn RJ, Walker AM, et al. Inhibition of clinical benefits of aspirin on first myocardial infarction by nonsteroidal antiinflammatory drugs. Circulation 2003; 108(10): 1191-5.
    • (2003) Circulation , vol.108 , Issue.10 , pp. 1191-1195
    • Kurth, T.1    Glynn, R.J.2    Walker, A.M.3
  • 102
    • 0037442182 scopus 로고    scopus 로고
    • Effect of ibuprofen on cardioprotective effect of aspirin
    • MacDonald TM, Wei L. Effect of ibuprofen on cardioprotective effect of aspirin. Lancet 2003; 361(9357): 573-4.
    • (2003) Lancet , vol.361 , Issue.9357 , pp. 573-574
    • Macdonald, T.M.1    Wei, L.2
  • 103
    • 0028866519 scopus 로고
    • Hyperlipidemia and coronary disease. Correction of the increased thrombogenic potential with cholesterol reduction
    • Lacoste L, Lam JY, Hung J, Letchacovski G, Solymoss CB, Waters D. Hyperlipidemia and coronary disease. Correction of the increased thrombogenic potential with cholesterol reduction. Circulation 1995; 92(11): 3172-7.
    • (1995) Circulation , vol.92 , Issue.11 , pp. 3172-3177
    • Lacoste, L.1    Lam, J.Y.2    Hung, J.3    Letchacovski, G.4    Solymoss, C.B.5    Waters, D.6
  • 104
    • 0033117022 scopus 로고    scopus 로고
    • Pravastatin therapy in hyperlipidemia: Effects on thrombus formation and the systemic hemostatic profile
    • Dangas G, Badimon JJ, Smith DA, et al. Pravastatin therapy in hyperlipidemia: effects on thrombus formation and the systemic hemostatic profile. J Am Coll Cardiol 1999; 33(5): 1294-304.
    • (1999) J Am Coll Cardiol , vol.33 , Issue.5 , pp. 1294-1304
    • Dangas, G.1    Badimon, J.J.2    Smith, D.A.3
  • 105
    • 13444309298 scopus 로고    scopus 로고
    • Short-term treatment with atorvastatin reduces platelet CD40 ligand and thrombin generation in hypercholesterolemic patients
    • Sanguigni V, Pignatelli P, Lenti L, et al. Short-term treatment with atorvastatin reduces platelet CD40 ligand and thrombin generation in hypercholesterolemic patients. Circulation 2005; 111(4): 412-9.
    • (2005) Circulation , vol.111 , Issue.4 , pp. 412-419
    • Sanguigni, V.1    Pignatelli, P.2    Lenti, L.3
  • 106
    • 79751481982 scopus 로고    scopus 로고
    • Statins have an early antiplatelet effect in patients with acute myocardial infarction
    • Matetzky S, Fefer P, Shenkman B, et al. Statins have an early antiplatelet effect in patients with acute myocardial infarction. Platelets 2011; 22(2): 103-10.
    • (2011) Platelets , vol.22 , Issue.2 , pp. 103-110
    • Matetzky, S.1    Fefer, P.2    Shenkman, B.3
  • 107
    • 33750079553 scopus 로고    scopus 로고
    • Influence of omeprazol on the antiplatelet action of clopidogrel associated to aspirin
    • Gilard M, Arnaud B, Le GG, Abgrall JF, Boschat J. Influence of omeprazol on the antiplatelet action of clopidogrel associated to aspirin. J Thromb Haemost 2006; 4(11): 2508-9.
    • (2006) J Thromb Haemost , vol.4 , Issue.11 , pp. 2508-2509
    • Gilard, M.1    Arnaud, B.2    Le, G.G.3    Abgrall, J.F.4    Boschat, J.5
  • 108
    • 62649164844 scopus 로고    scopus 로고
    • A population-based study of the drug interaction between proton pump inhibitors and clopidogrel
    • Juurlink DN, Gomes T, Ko DT, et al. A population-based study of the drug interaction between proton pump inhibitors and clopidogrel. CMAJ 2009; 180(7): 713-8.
    • (2009) CMAJ , vol.180 , Issue.7 , pp. 713-718
    • Juurlink, D.N.1    Gomes, T.2    Ko, D.T.3
  • 109
    • 65349111293 scopus 로고    scopus 로고
    • The drug-drug interaction between proton pump inhibitors and clopidogrel
    • Lau WC, Gurbel PA. The drug-drug interaction between proton pump inhibitors and clopidogrel. CMAJ 2009; 180(7): 699-700.
    • (2009) CMAJ , vol.180 , Issue.7 , pp. 699-700
    • Lau, W.C.1    Gurbel, P.A.2
  • 110
    • 80054919425 scopus 로고    scopus 로고
    • Clinical, angiographic, and genetic factors associated with early coronary stent thrombosis
    • Cayla G, Hulot JS, O'Connor SA, et al. Clinical, angiographic, and genetic factors associated with early coronary stent thrombosis. JAMA 2011; 306(16): 1765-74.
    • (2011) JAMA , vol.306 , Issue.16 , pp. 1765-1774
    • Cayla, G.1    Hulot, J.S.2    O'Connor, S.A.3
  • 111
    • 70249139788 scopus 로고    scopus 로고
    • Pharmacodynamic effect and clinical efficacy of clopidogrel and prasugrel with or without a proton-pump inhibitor: An analysis of two randomised trials
    • O'Donoghue ML, Braunwald E, Antman EM, et al. Pharmacodynamic effect and clinical efficacy of clopidogrel and prasugrel with or without a proton-pump inhibitor: an analysis of two randomised trials. Lancet 2009; 374(9694): 989-97.
    • (2009) Lancet , vol.374 , Issue.9694 , pp. 989-997
    • O'Donoghue, M.L.1    Braunwald, E.2    Antman, E.M.3
  • 112
    • 84857992585 scopus 로고    scopus 로고
    • Association of Proton Pump Inhibitor Use on Cardiovascular Outcomes with Clopidogrel and Ticagrelor: Insights from PLATO
    • Goodman SG, Clare R, Pieper KS, et al. Association of Proton Pump Inhibitor Use on Cardiovascular Outcomes with Clopidogrel and Ticagrelor: Insights from PLATO. Circulation 2012; 125(8): 978-86.
    • (2012) Circulation , vol.125 , Issue.8 , pp. 978-986
    • Goodman, S.G.1    Clare, R.2    Pieper, K.S.3
  • 113
    • 78649696637 scopus 로고    scopus 로고
    • ACCF/ACG/AHA 2010 expert consensus document on the concomitant use of proton pump inhibitors and thienopyridines: A focused update of the ACCF/ACG/AHA 2008 expert consensus document on reducing the gastrointestinal risks of antiplatelet therapy and NSAID use. A Report of the American College of Cardiology Foundation Task Force on Expert Consensus Documents
    • Abraham NS, Hlatky MA, Antman EM, et al. ACCF/ACG/AHA 2010 expert consensus document on the concomitant use of proton pump inhibitors and thienopyridines: a focused update of the ACCF/ACG/AHA 2008 expert consensus document on reducing the gastrointestinal risks of antiplatelet therapy and NSAID use. A Report of the American College of Cardiology Foundation Task Force on Expert Consensus Documents. J Am Coll Cardiol 2010; 56(24): 2051-66.
    • (2010) J Am Coll Cardiol , vol.56 , Issue.24 , pp. 2051-2066
    • Abraham, N.S.1    Hlatky, M.A.2    Antman, E.M.3
  • 114
    • 80051533777 scopus 로고    scopus 로고
    • Bleeding in acute coronary syndromes and percutaneous coronary interventions: Position paper by the Working Group on Thrombosis of the European Society of Cardiology
    • Steg PG, Huber K, Andreotti F, et al. Bleeding in acute coronary syndromes and percutaneous coronary interventions: position paper by the Working Group on Thrombosis of the European Society of Cardiology. Eur Heart J 2011; 32(15): 1854-64.
    • (2011) Eur Heart J , vol.32 , Issue.15 , pp. 1854-1864
    • Steg, P.G.1    Huber, K.2    Andreotti, F.3
  • 115
    • 0037422534 scopus 로고    scopus 로고
    • Atorvastatin reduces the ability of clopidogrel to inhibit platelet aggregation: A new drugdrug interaction
    • Lau WC, Waskell LA, Watkins PB, et al. Atorvastatin reduces the ability of clopidogrel to inhibit platelet aggregation: a new drugdrug interaction. Circulation 2003; 107(1): 32-7.
    • (2003) Circulation , vol.107 , Issue.1 , pp. 32-37
    • Lau, W.C.1    Waskell, L.A.2    Watkins, P.B.3
  • 116
    • 0141986521 scopus 로고    scopus 로고
    • Lipophilic statins interfere with the inhibitory effects of clopidogrel on platelet function--a flow cytometry study
    • Neubauer H, Gunesdogan B, Hanefeld C, Spiecker M, Mugge A. Lipophilic statins interfere with the inhibitory effects of clopidogrel on platelet function--a flow cytometry study. Eur Heart J 2003; 24(19): 1744-9.
    • (2003) Eur Heart J , vol.24 , Issue.19 , pp. 1744-1749
    • Neubauer, H.1    Gunesdogan, B.2    Hanefeld, C.3    Spiecker, M.4    Mugge, A.5
  • 117
    • 6344226832 scopus 로고    scopus 로고
    • Absence of interaction between atorvastatin or other statins and clopidogrel: Results from the interaction study
    • Serebruany VL, Midei MG, Malinin AI, et al. Absence of interaction between atorvastatin or other statins and clopidogrel: results from the interaction study. Arch Intern Med 2004; 164(18): 2051-7.
    • (2004) Arch Intern Med , vol.164 , Issue.18 , pp. 2051-2057
    • Serebruany, V.L.1    Midei, M.G.2    Malinin, A.I.3
  • 118
    • 1642410985 scopus 로고    scopus 로고
    • Atorvastatin does not affect the antiplatelet potency of clopidogrel when it is administered concomitantly for 5 weeks in patients with acute coronary syndromes
    • Mitsios JV, Papathanasiou AI, Rodis FI, Elisaf M, Goudevenos JA, Tselepis AD. Atorvastatin does not affect the antiplatelet potency of clopidogrel when it is administered concomitantly for 5 weeks in patients with acute coronary syndromes. Circulation 2004; 109(11): 1335-8.
    • (2004) Circulation , vol.109 , Issue.11 , pp. 1335-1338
    • Mitsios, J.V.1    Papathanasiou, A.I.2    Rodis, F.I.3    Elisaf, M.4    Goudevenos, J.A.5    Tselepis, A.D.6
  • 119
    • 70349887593 scopus 로고    scopus 로고
    • Influence of statin treatment on platelet inhibition by clopidogrel a randomized comparison of rosuvastatin, atorvastatin and simvastatin cotreatment
    • Malmstrom RE, Ostergren J, Jorgensen L, Hjemdahl P. Influence of statin treatment on platelet inhibition by clopidogrel a randomized comparison of rosuvastatin, atorvastatin and simvastatin cotreatment. J Intern Med 2009; 266(5): 457-66.
    • (2009) J Intern Med , vol.266 , Issue.5 , pp. 457-466
    • Malmstrom, R.E.1    Ostergren, J.2    Jorgensen, L.3    Hjemdahl, P.4
  • 120
    • 10844240637 scopus 로고    scopus 로고
    • Lack of clopidogrel-CYP3A4 statin interaction in patients with acute coronary syndrome
    • Mukherjee D, Kline-Rogers E, Fang J, Munir K, Eagle KA. Lack of clopidogrel-CYP3A4 statin interaction in patients with acute coronary syndrome. Heart 2005; 91(1): 23-6.
    • (2005) Heart , vol.91 , Issue.1 , pp. 23-26
    • Mukherjee, D.1    Kline-Rogers, E.2    Fang, J.3    Munir, K.4    Eagle, K.A.5
  • 121
    • 34447332809 scopus 로고    scopus 로고
    • Clopidogrel-statin interaction: Myth or reality?
    • Angiolillo DJ, Alfonso F. Clopidogrel-statin interaction: myth or reality? J Am Coll Cardiol 2007; 50(4): 296-8.
    • (2007) J Am Coll Cardiol , vol.50 , Issue.4 , pp. 296-298
    • Angiolillo, D.J.1    Alfonso, F.2
  • 122
    • 34447312473 scopus 로고    scopus 로고
    • Lack of evidence of a clopidogrel-statin interaction in the CHARISMA trial
    • Saw J, Brennan DM, Steinhubl SR, et al. Lack of evidence of a clopidogrel-statin interaction in the CHARISMA trial. J Am Coll Cardiol 2007; 50(4): 291-5.
    • (2007) J Am Coll Cardiol , vol.50 , Issue.4 , pp. 291-295
    • Saw, J.1    Brennan, D.M.2    Steinhubl, S.R.3
  • 123
    • 42649083329 scopus 로고    scopus 로고
    • High-dose atorvastatin does not negatively influence clinical outcomes among clopidogrel treated acute coronary syndrome patients--a Pravastatin or Atorvastatin Evaluation and Infection Therapy-Thrombolysis in Myocardial Infarction 22 (PROVE IT-TIMI 22) analysis
    • Lotfi A, Schweiger MJ, Giugliano GR, Murphy SA, Cannon CP. High-dose atorvastatin does not negatively influence clinical outcomes among clopidogrel treated acute coronary syndrome patients--a Pravastatin or Atorvastatin Evaluation and Infection Therapy-Thrombolysis in Myocardial Infarction 22 (PROVE IT-TIMI 22) analysis. Am Heart J 2008; 155(5): 954-8.
    • (2008) Am Heart J , vol.155 , Issue.5 , pp. 954-958
    • Lotfi, A.1    Schweiger, M.J.2    Giugliano, G.R.3    Murphy, S.A.4    Cannon, C.P.5
  • 124
    • 38349168982 scopus 로고    scopus 로고
    • Impact of cytochrome P450 3A4-metabolized statins on the antiplatelet effect of a 600-mg loading dose clopidogrel and on clinical outcome in patients undergoing elective coronary stent placement
    • Trenk D, Hochholzer W, Frundi D, et al. Impact of cytochrome P450 3A4-metabolized statins on the antiplatelet effect of a 600-mg loading dose clopidogrel and on clinical outcome in patients undergoing elective coronary stent placement. Thromb Haemost 2008; 99(1): 174-81.
    • (2008) Thromb Haemost , vol.99 , Issue.1 , pp. 174-181
    • Trenk, D.1    Hochholzer, W.2    Frundi, D.3
  • 125
    • 54349121974 scopus 로고    scopus 로고
    • Calcium-channel blockers reduce the antiplatelet effect of clopidogrel
    • Siller-Matula JM, Lang I, Christ G, Jilma B. Calcium-channel blockers reduce the antiplatelet effect of clopidogrel. J Am Coll Cardiol 2008; 52(19): 1557-63.
    • (2008) J Am Coll Cardiol , vol.52 , Issue.19 , pp. 1557-1563
    • Siller-Matula, J.M.1    Lang, I.2    Christ, G.3    Jilma, B.4
  • 127
    • 79952444959 scopus 로고    scopus 로고
    • Lack of impact of calcium-channel blockers on the pharmacodynamic effect and the clinical efficacy of clopidogrel after drug-eluting stenting
    • Sarafoff N, Neumann L, Morath T, et al. Lack of impact of calcium-channel blockers on the pharmacodynamic effect and the clinical efficacy of clopidogrel after drug-eluting stenting. Am Heart J 2011; 161(3): 605-10.
    • (2011) Am Heart J , vol.161 , Issue.3 , pp. 605-610
    • Sarafoff, N.1    Neumann, L.2    Morath, T.3
  • 128
    • 77952400164 scopus 로고    scopus 로고
    • Oral anticoagulation with coumarin derivatives and antiplatelet effects of clopidogrel
    • Sibbing D, von BN, Morath T, et al. Oral anticoagulation with coumarin derivatives and antiplatelet effects of clopidogrel. Eur Heart J 2010; 31(10): 1205-11.
    • (2010) Eur Heart J , vol.31 , Issue.10 , pp. 1205-1211
    • Sibbing, D.1    von, B.N.2    Morath, T.3
  • 129
    • 77958608904 scopus 로고    scopus 로고
    • Potentiation of clopidogrel active metabolite formation by rifampicin leads to greater P2Y12 receptor blockade and inhibition of platelet aggregation after clopidogrel
    • Judge HM, Patil SB, Buckland RJ, Jakubowski JA, Storey RF. Potentiation of clopidogrel active metabolite formation by rifampicin leads to greater P2Y12 receptor blockade and inhibition of platelet aggregation after clopidogrel. J Thromb Haemost 2010; 8(8): 1820-7.
    • (2010) J Thromb Haemost , vol.8 , Issue.8 , pp. 1820-1827
    • Judge, H.M.1    Patil, S.B.2    Buckland, R.J.3    Jakubowski, J.A.4    Storey, R.F.5
  • 130
    • 67649654260 scopus 로고    scopus 로고
    • Antiplatelet drug 'resistance'. Part 1: Mechanisms and clinical measurements
    • Sweeny JM, Gorog DA, Fuster V. Antiplatelet drug 'resistance'. Part 1: mechanisms and clinical measurements. Nat Rev Cardiol 2009; 6(4): 273-82.
    • (2009) Nat Rev Cardiol , vol.6 , Issue.4 , pp. 273-282
    • Sweeny, J.M.1    Gorog, D.A.2    Fuster, V.3
  • 131
    • 60849111109 scopus 로고    scopus 로고
    • Immature platelets in patients with acute coronary syndromes
    • Jan
    • Grove EL, Hvas AM, Kristensen SD. Immature platelets in patients with acute coronary syndromes. Thromb Haemost 2009 Jan; 101(1): 151-6.
    • (2009) Thromb Haemost , vol.101 , Issue.1 , pp. 151-156
    • Grove, E.L.1    Hvas, A.M.2    Kristensen, S.D.3
  • 133
    • 78651333187 scopus 로고    scopus 로고
    • Patients With Previous Definite Stent Thrombosis Have a Reduced Antiplatelet Effect of Aspirin and a Larger Fraction of Immature Platelets
    • Wurtz M, Grove EL, Wulff LN, et al. Patients With Previous Definite Stent Thrombosis Have a Reduced Antiplatelet Effect of Aspirin and a Larger Fraction of Immature Platelets. JACC Cardiovasc Interv 2010; 3(8): 828-35.
    • (2010) JACC Cardiovasc Interv , vol.3 , Issue.8 , pp. 828-835
    • Wurtz, M.1    Grove, E.L.2    Wulff, L.N.3
  • 134
    • 79959835019 scopus 로고    scopus 로고
    • Increased platelet turnover in patients with previous definite stent thrombosis
    • Grove EL, Wurtz M, Hvas AM, Kristensen SD. Increased platelet turnover in patients with previous definite stent thrombosis. J Thromb Haemost 2011; 9(7): 1418-9.
    • (2011) J Thromb Haemost , vol.9 , Issue.7 , pp. 1418-1419
    • Grove, E.L.1    Wurtz, M.2    Hvas, A.M.3    Kristensen, S.D.4
  • 135
    • 34247574729 scopus 로고    scopus 로고
    • Reticulated platelets and uninhibited COX-1 and COX-2 decrease the antiplatelet effects of aspirin
    • Guthikonda S, Lev EI, Patel R, et al. Reticulated platelets and uninhibited COX-1 and COX-2 decrease the antiplatelet effects of aspirin. J Thromb Haemost 2007; 5(3): 490-6.
    • (2007) J Thromb Haemost , vol.5 , Issue.3 , pp. 490-496
    • Guthikonda, S.1    Lev, E.I.2    Patel, R.3
  • 136
    • 49349102948 scopus 로고    scopus 로고
    • Role of reticulated platelets and platelet size heterogeneity on platelet activity after dual antiplatelet therapy with aspirin and clopidogrel in patients with stable coronary artery disease
    • Guthikonda S, Alviar CL, Vaduganathan M, et al. Role of reticulated platelets and platelet size heterogeneity on platelet activity after dual antiplatelet therapy with aspirin and clopidogrel in patients with stable coronary artery disease. J Am Coll Cardiol 2008; 52(9): 743-9.
    • (2008) J Am Coll Cardiol , vol.52 , Issue.9 , pp. 743-749
    • Guthikonda, S.1    Alviar, C.L.2    Vaduganathan, M.3
  • 137
    • 43949115561 scopus 로고    scopus 로고
    • Relationship between high platelet turnover and platelet function in high-risk patients with coronary artery disease on dual antiplatelet therapy
    • Cesari F, Marcucci R, Caporale R, et al. Relationship between high platelet turnover and platelet function in high-risk patients with coronary artery disease on dual antiplatelet therapy. Thromb Haemost 2008; 99(5): 930-5.
    • (2008) Thromb Haemost , vol.99 , Issue.5 , pp. 930-935
    • Cesari, F.1    Marcucci, R.2    Caporale, R.3
  • 138
    • 9144270451 scopus 로고    scopus 로고
    • Expert consensus document on the use of antiplatelet agents. The task force on the use of antiplatelet agents in patients with atherosclerotic cardiovascular disease of the European society of cardiology
    • Patrono C, Bachmann F, Baigent C, et al. Expert consensus document on the use of antiplatelet agents. The task force on the use of antiplatelet agents in patients with atherosclerotic cardiovascular disease of the European society of cardiology. Eur Heart J 2004; 25(2): 166-81.
    • (2004) Eur Heart J , vol.25 , Issue.2 , pp. 166-181
    • Patrono, C.1    Bachmann, F.2    Baigent, C.3
  • 140
    • 42249094289 scopus 로고    scopus 로고
    • Variability of response to antiplatelet therapy
    • Storey RF. Variability of response to antiplatelet therapy. Eur Heart J 2008; 10(Suppl. A): A21-A27.
    • (2008) Eur Heart J , vol.10 , Issue.SUPPL. A
    • Storey, R.F.1
  • 141
    • 79960034076 scopus 로고    scopus 로고
    • Is increased platelet turnover responsible for low responsiveness to different thienopyridienes? A case report of recurrent stent thromboses
    • Freynhofer MK, Bruno V, Brozovic I, et al. Is increased platelet turnover responsible for low responsiveness to different thienopyridienes? A case report of recurrent stent thromboses. Thromb Haemost 2011; 106(1): 182-4.
    • (2011) Thromb Haemost , vol.106 , Issue.1 , pp. 182-184
    • Freynhofer, M.K.1    Bruno, V.2    Brozovic, I.3
  • 142
    • 79961114506 scopus 로고    scopus 로고
    • Intrinsic platelet reactivity before P2Y12 blockade contributes to residual platelet reactivity despite high-level P2Y12 blockade by prasugrel or highdose clopidogrel. Results from PRINCIPLE-TIMI 44
    • Frelinger AL3rd, Michelson AD, Wiviott SD, et al. Intrinsic platelet reactivity before P2Y12 blockade contributes to residual platelet reactivity despite high-level P2Y12 blockade by prasugrel or highdose clopidogrel. Results from PRINCIPLE-TIMI 44. Thromb Haemost 2011; 106(2): 219-26.
    • (2011) Thromb Haemost , vol.106 , Issue.2 , pp. 219-226
    • Frelinger III, A.L.1    Michelson, A.D.2    Wiviott, S.D.3
  • 143
    • 27144453722 scopus 로고    scopus 로고
    • Aggregometry detects platelet hyperreactivity in healthy individuals
    • Yee DL, Sun CW, Bergeron AL, Dong JF, Bray PF. Aggregometry detects platelet hyperreactivity in healthy individuals. Blood 2005; 106(8): 2723-9.
    • (2005) Blood , vol.106 , Issue.8 , pp. 2723-2729
    • Yee, D.L.1    Sun, C.W.2    Bergeron, A.L.3    Dong, J.F.4    Bray, P.F.5
  • 144
    • 34948875324 scopus 로고    scopus 로고
    • Impact of platelet reactivity on cardiovascular outcomes in patients with type 2 diabetes mellitus and coronary artery disease
    • Angiolillo DJ, Bernardo E, Sabate M, et al. Impact of platelet reactivity on cardiovascular outcomes in patients with type 2 diabetes mellitus and coronary artery disease. J Am Coll Cardiol 2007; 50(16): 1541-7.
    • (2007) J Am Coll Cardiol , vol.50 , Issue.16 , pp. 1541-1547
    • Angiolillo, D.J.1    Bernardo, E.2    Sabate, M.3
  • 145
    • 29344466941 scopus 로고    scopus 로고
    • Aspirin and clopidogrel drug response in patients undergoing percutaneous coronary intervention: The role of dual drug resistance
    • Lev EI, Patel RT, Maresh KJ, et al. Aspirin and clopidogrel drug response in patients undergoing percutaneous coronary intervention: the role of dual drug resistance. J Am Coll Cardiol 2006; 47(1): 27-33.
    • (2006) J Am Coll Cardiol , vol.47 , Issue.1 , pp. 27-33
    • Lev, E.I.1    Patel, R.T.2    Maresh, K.J.3
  • 146
    • 33845528397 scopus 로고    scopus 로고
    • Evidence that preexistent variability in platelet response to ADP accounts for 'clopidogrel resistance'
    • Michelson AD, Linden MD, Furman MI, et al. Evidence that preexistent variability in platelet response to ADP accounts for 'clopidogrel resistance'. J Thromb Haemost 2007; 5(1): 75-81.
    • (2007) J Thromb Haemost , vol.5 , Issue.1 , pp. 75-81
    • Michelson, A.D.1    Linden, M.D.2    Furman, M.I.3
  • 147
    • 56749182302 scopus 로고    scopus 로고
    • Aspirin resistance: Role of pre-existent platelet reactivity and correlation between tests
    • Frelinger AL, Li Y, Linden MD, et al. Aspirin resistance: role of pre-existent platelet reactivity and correlation between tests. J Thromb Haemost 2008; 6(12): 2035-44.
    • (2008) J Thromb Haemost , vol.6 , Issue.12 , pp. 2035-2044
    • Frelinger, A.L.1    Li, Y.2    Linden, M.D.3
  • 148
    • 33747088257 scopus 로고    scopus 로고
    • Residual arachidonic acid-induced platelet activation via an adenosine diphosphate-dependent but cyclooxygenase-1and cyclooxygenase-2independent pathway: A 700-patient study of aspirin resistance
    • Frelinger AL3rd, Furman MI, Linden MD, et al. Residual arachidonic acid-induced platelet activation via an adenosine diphosphate-dependent but cyclooxygenase-1and cyclooxygenase-2independent pathway: a 700-patient study of aspirin resistance. Circulation 2006; 113(25): 2888-96.
    • (2006) Circulation , vol.113 , Issue.25 , pp. 2888-2896
    • Frelinger III, A.L.1    Furman, M.I.2    Linden, M.D.3
  • 149
    • 73949093109 scopus 로고    scopus 로고
    • Association of cyclooxygenase-1-dependent and -independent platelet function assays with adverse clinical outcomes in aspirin-treated patients presenting for cardiac catheterization
    • Frelinger AL3rd, Li Y, Linden MD, et al. Association of cyclooxygenase-1-dependent and -independent platelet function assays with adverse clinical outcomes in aspirin-treated patients presenting for cardiac catheterization. Circulation 2009; 120(25): 2586-96.
    • (2009) Circulation , vol.120 , Issue.25 , pp. 2586-2596
    • Frelinger III, A.L.1    Li, Y.2    Linden, M.D.3
  • 150
    • 84858127301 scopus 로고    scopus 로고
    • High platelet reactivity and antiplatelet therapy resistance
    • Linden MD, Tran H, Woods R, Tonkin A. High platelet reactivity and antiplatelet therapy resistance. Semin Thromb Hemost 2012; 38(2): 200-12.
    • (2012) Semin Thromb Hemost , vol.38 , Issue.2 , pp. 200-212
    • Linden, M.D.1    Tran, H.2    Woods, R.3    Tonkin, A.4
  • 151
    • 0037421584 scopus 로고    scopus 로고
    • Inheritance and drug response
    • Weinshilboum R. Inheritance and drug response. N Engl J Med 2003; 348(6): 529-37.
    • (2003) N Engl J Med , vol.348 , Issue.6 , pp. 529-537
    • Weinshilboum, R.1
  • 152
    • 0035954288 scopus 로고    scopus 로고
    • Genetic and environmental contributions to platelet aggregation: The Framingham heart study
    • O'Donnell CJ, Larson MG, Feng D, et al. Genetic and environmental contributions to platelet aggregation: the Framingham heart study. Circulation 2001; 103(25): 3051-6.
    • (2001) Circulation , vol.103 , Issue.25 , pp. 3051-3056
    • O'Donnell, C.J.1    Larson, M.G.2    Feng, D.3
  • 153
    • 47249143688 scopus 로고    scopus 로고
    • Pharmacogenetics of aspirin resistance: A comprehensive systematic review
    • Goodman T, Ferro A, Sharma P. Pharmacogenetics of aspirin resistance: a comprehensive systematic review. Br J Clin Pharmacol 2008; 66(2): 222-32.
    • (2008) Br J Clin Pharmacol , vol.66 , Issue.2 , pp. 222-232
    • Goodman, T.1    Ferro, A.2    Sharma, P.3
  • 155
    • 77955638355 scopus 로고    scopus 로고
    • ACCF/AHA clopidogrel clinical alert: Approaches to the FDA boxed warning: A report of the American College of Cardiology Foundation Task Force on clinical expert consensus documents and the American Heart Association endorsed by the Society for Cardiovascular Angiography and Interventions and the Society of Thoracic Surgeons
    • Holmes DR, Jr., Dehmer GJ, Kaul S, Leifer D, O'Gara PT, Stein CM. ACCF/AHA clopidogrel clinical alert: approaches to the FDA boxed warning: a report of the American College of Cardiology Foundation Task Force on clinical expert consensus documents and the American Heart Association endorsed by the Society for Cardiovascular Angiography and Interventions and the Society of Thoracic Surgeons. J Am Coll Cardiol 2010; 56(4): 321-41.
    • (2010) J Am Coll Cardiol , vol.56 , Issue.4 , pp. 321-341
    • Holmes Jr., D.R.1    Dehmer, G.J.2    Kaul, S.3    Leifer, D.4    O'Gara, P.T.5    Stein, C.M.6
  • 156
    • 33749339075 scopus 로고    scopus 로고
    • Cytochrome P450 2C19 loss-offunction polymorphism is a major determinant of clopidogrel responsiveness in healthy subjects
    • Hulot JS, Bura A, Villard E, et al. Cytochrome P450 2C19 loss-offunction polymorphism is a major determinant of clopidogrel responsiveness in healthy subjects. Blood 2006; 108(7): 2244-7.
    • (2006) Blood , vol.108 , Issue.7 , pp. 2244-2247
    • Hulot, J.S.1    Bura, A.2    Villard, E.3
  • 157
    • 58249135635 scopus 로고    scopus 로고
    • Cytochrome P450 2C19 polymorphism in young patients treated with clopidogrel after myocardial infarction: A cohort study
    • Collet JP, Hulot JS, Pena A, et al. Cytochrome P450 2C19 polymorphism in young patients treated with clopidogrel after myocardial infarction: a cohort study. Lancet 2009; 373(9660): 309-17.
    • (2009) Lancet , vol.373 , Issue.9660 , pp. 309-317
    • Collet, J.P.1    Hulot, J.S.2    Pena, A.3
  • 158
    • 69249219296 scopus 로고    scopus 로고
    • Association of cytochrome P450 2C19 genotype with the antiplatelet effect and clinical efficacy of clopidogrel therapy
    • Shuldiner AR, O'Connell JR, Bliden KP, et al. Association of cytochrome P450 2C19 genotype with the antiplatelet effect and clinical efficacy of clopidogrel therapy. JAMA 2009; 302(8): 849-57.
    • (2009) JAMA , vol.302 , Issue.8 , pp. 849-857
    • Shuldiner, A.R.1    O'Connell, J.R.2    Bliden, K.P.3
  • 159
    • 78049326068 scopus 로고    scopus 로고
    • Reduced-function CYP2C19 genotype and risk of adverse clinical outcomes among patients treated with clopidogrel predominantly for PCI: A meta-analysis
    • Mega JL, Simon T, Collet JP, et al. Reduced-function CYP2C19 genotype and risk of adverse clinical outcomes among patients treated with clopidogrel predominantly for PCI: a meta-analysis. JAMA 2010; 304(16): 1821-30.
    • (2010) JAMA , vol.304 , Issue.16 , pp. 1821-1830
    • Mega, J.L.1    Simon, T.2    Collet, J.P.3
  • 160
    • 79958110089 scopus 로고    scopus 로고
    • Prospective evaluation of on-clopidogrel platelet reactivity over time in patients treated with percutaneous coronary intervention relationship with gene polymorphisms and clinical outcome
    • Campo G, Parrinello G, Ferraresi P, et al. Prospective evaluation of on-clopidogrel platelet reactivity over time in patients treated with percutaneous coronary intervention relationship with gene polymorphisms and clinical outcome. J Am Coll Cardiol 2011; 57(25): 2474-83.
    • (2011) J Am Coll Cardiol , vol.57 , Issue.25 , pp. 2474-2483
    • Campo, G.1    Parrinello, G.2    Ferraresi, P.3
  • 161
    • 80052285369 scopus 로고    scopus 로고
    • Usefulness of high clopidogrel maintenance dose according to CYP2C19 genotypes in clopidogrel low responders undergoing coronary stenting for non ST elevation acute coronary syndrome
    • Cuisset T, Quilici J, Cohen W, et al. Usefulness of high clopidogrel maintenance dose according to CYP2C19 genotypes in clopidogrel low responders undergoing coronary stenting for non ST elevation acute coronary syndrome. Am J Cardiol 2011; 108(6): 760-5.
    • (2011) Am J Cardiol , vol.108 , Issue.6 , pp. 760-765
    • Cuisset, T.1    Quilici, J.2    Cohen, W.3
  • 162
    • 84555195438 scopus 로고    scopus 로고
    • CYP2C19 genotype, clopidogrel metabolism, platelet function, and cardiovascular events: A systematic review and meta-analysis
    • Holmes MV, Perel P, Shah T, Hingorani AD, Casas JP. CYP2C19 genotype, clopidogrel metabolism, platelet function, and cardiovascular events: a systematic review and meta-analysis. JAMA 2011; 306(24): 2704-14.
    • (2011) JAMA , vol.306 , Issue.24 , pp. 2704-2714
    • Holmes, M.V.1    Perel, P.2    Shah, T.3    Hingorani, A.D.4    Casas, J.P.5
  • 163
    • 81855211733 scopus 로고    scopus 로고
    • Dosing clopidogrel based on CYP2C19 genotype and the effect on platelet reactivity in patients with stable cardiovascular disease
    • Mega JL, Hochholzer W, Frelinger AL, III, et al. Dosing clopidogrel based on CYP2C19 genotype and the effect on platelet reactivity in patients with stable cardiovascular disease. JAMA 2011; 306(20): 2221-8.
    • (2011) JAMA , vol.306 , Issue.20 , pp. 2221-2228
    • Mega, J.L.1    Hochholzer, W.2    Frelinger III, A.L.3
  • 164
    • 77958105401 scopus 로고    scopus 로고
    • Genetic variants in ABCB1 and CYP2C19 and cardiovascular outcomes after treatment with clopidogrel and prasugrel in the TRITON-TIMI 38 trial: A pharmacogenetic analysis
    • Mega JL, Close SL, Wiviott SD, et al. Genetic variants in ABCB1 and CYP2C19 and cardiovascular outcomes after treatment with clopidogrel and prasugrel in the TRITON-TIMI 38 trial: a pharmacogenetic analysis. Lancet 2010; 376(9749): 1312-9.
    • (2010) Lancet , vol.376 , Issue.9749 , pp. 1312-1319
    • Mega, J.L.1    Close, S.L.2    Wiviott, S.D.3
  • 165
    • 77958100874 scopus 로고    scopus 로고
    • Effect of CYP2C19 and ABCB1 single nucleotide polymorphisms on outcomes of treatment with ticagrelor versus clopidogrel for acute coronary syndromes: A genetic substudy of the PLATO trial
    • Wallentin L, James S, Storey RF, et al. Effect of CYP2C19 and ABCB1 single nucleotide polymorphisms on outcomes of treatment with ticagrelor versus clopidogrel for acute coronary syndromes: a genetic substudy of the PLATO trial. Lancet 2010; 376(9749): 1320-8.
    • (2010) Lancet , vol.376 , Issue.9749 , pp. 1320-1328
    • Wallentin, L.1    James, S.2    Storey, R.F.3
  • 166
    • 78651239845 scopus 로고    scopus 로고
    • Paraoxonase-1 is a major determinant of clopidogrel efficacy
    • Bouman HJ, Schomig E, van Werkum JW, et al. Paraoxonase-1 is a major determinant of clopidogrel efficacy. Nat Med 2011; 17(1): 110-6.
    • (2011) Nat Med , vol.17 , Issue.1 , pp. 110-116
    • Bouman, H.J.1    Schomig, E.2    van Werkum, J.W.3
  • 167
    • 79960012663 scopus 로고    scopus 로고
    • No association of paraoxonase-1 Q192R genotypes with platelet response to clopidogrel and risk of stent thrombosis after coronary stenting
    • Sibbing D, Koch W, Massberg S, et al. No association of paraoxonase-1 Q192R genotypes with platelet response to clopidogrel and risk of stent thrombosis after coronary stenting. Eur Heart J 2011; 32(13): 1605-13.
    • (2011) Eur Heart J , vol.32 , Issue.13 , pp. 1605-1613
    • Sibbing, D.1    Koch, W.2    Massberg, S.3
  • 168
    • 82955240702 scopus 로고    scopus 로고
    • CYP2C19 But Not PON1 Genetic Variants Influence Clopidogrel Pharmacokinetics, Pharmacodynamics, and Clinical Efficacy in Post-Myocardial Infarction Patients
    • Hulot JS, Collet JP, Cayla G, et al. CYP2C19 But Not PON1 Genetic Variants Influence Clopidogrel Pharmacokinetics, Pharmacodynamics, and Clinical Efficacy in Post-Myocardial Infarction Patients. Circ Cardiovasc Interv 2011; 4(5): 422-8.
    • (2011) Circ Cardiovasc Interv , vol.4 , Issue.5 , pp. 422-428
    • Hulot, J.S.1    Collet, J.P.2    Cayla, G.3
  • 169
    • 0033800745 scopus 로고    scopus 로고
    • Effects of obesity on pharmacokinetics implications for drug therapy
    • Cheymol G. Effects of obesity on pharmacokinetics implications for drug therapy. Clin Pharmacokinet 2000; 39(3): 215-31.
    • (2000) Clin Pharmacokinet , vol.39 , Issue.3 , pp. 215-231
    • Cheymol, G.1
  • 170
    • 0043167980 scopus 로고    scopus 로고
    • Obesity is associated with impaired platelet-inhibitory effect of acetylsalicylic acid in nondiabetic subjects
    • Tamminen M, Lassila R, Westerbacka J, Vehkavaara S, Yki-Jarvinen H. Obesity is associated with impaired platelet-inhibitory effect of acetylsalicylic acid in nondiabetic subjects. Int J Obes Relat Metab Disord 2003; 27(8): 907-11.
    • (2003) Int J Obes Relat Metab Disord , vol.27 , Issue.8 , pp. 907-911
    • Tamminen, M.1    Lassila, R.2    Westerbacka, J.3    Vehkavaara, S.4    Yki-Jarvinen, H.5
  • 171
  • 172
    • 77954471043 scopus 로고    scopus 로고
    • Aspirin resistance is associated with glycemic control, the dose of aspirin, and obesity in type 2 diabetes mellitus
    • Ertugrul DT, Tutal E, Yildiz M, et al. Aspirin resistance is associated with glycemic control, the dose of aspirin, and obesity in type 2 diabetes mellitus. J Clin Endocrinol Metab 2010; 95(6): 2897-901.
    • (2010) J Clin Endocrinol Metab , vol.95 , Issue.6 , pp. 2897-2901
    • Ertugrul, D.T.1    Tutal, E.2    Yildiz, M.3
  • 173
    • 11144355993 scopus 로고    scopus 로고
    • Platelet aggregation according to body mass index in patients undergoing coronary stenting: Should clopidogrel loading-dose be weight adjusted?
    • Angiolillo DJ, Fernandez-Ortiz A, Bernardo E, et al. Platelet aggregation according to body mass index in patients undergoing coronary stenting: should clopidogrel loading-dose be weight adjusted? J Invasive Cardiol 2004; 16(4): 169-74.
    • (2004) J Invasive Cardiol , vol.16 , Issue.4 , pp. 169-174
    • Angiolillo, D.J.1    Fernandez-Ortiz, A.2    Bernardo, E.3
  • 174
    • 34447274446 scopus 로고    scopus 로고
    • Impact of body mass index on platelet aggregation after administration of a high loading dose of 600 mg of clopidogrel before percutaneous coronary intervention
    • Sibbing D, von BO, Schomig A, Kastrati A, von BN. Impact of body mass index on platelet aggregation after administration of a high loading dose of 600 mg of clopidogrel before percutaneous coronary intervention. Am J Cardiol 2007; 100(2): 203-5.
    • (2007) Am J Cardiol , vol.100 , Issue.2 , pp. 203-205
    • Sibbing, D.1    von, B.O.2    Schomig, A.3    Kastrati, A.4    von, B.N.5
  • 175
    • 34447282174 scopus 로고    scopus 로고
    • Clopidogrel resistance: Role of body mass and concomitant medications
    • Feher G, Koltai K, Alkonyi B, et al. Clopidogrel resistance: role of body mass and concomitant medications. Int J Cardiol 2007; 120(2): 188-92.
    • (2007) Int J Cardiol , vol.120 , Issue.2 , pp. 188-192
    • Feher, G.1    Koltai, K.2    Alkonyi, B.3
  • 176
    • 77952591958 scopus 로고    scopus 로고
    • Impact of cytochrome P450 2C19 loss-of-function polymorphism and of major demographic characteristics on residual platelet function after loading and maintenance treatment with clopidogrel in patients undergoing elective coronary stent placement
    • Hochholzer W, Trenk D, Fromm MF, et al. Impact of cytochrome P450 2C19 loss-of-function polymorphism and of major demographic characteristics on residual platelet function after loading and maintenance treatment with clopidogrel in patients undergoing elective coronary stent placement. J Am Coll Cardiol 2010; 55(22): 2427-34.
    • (2010) J Am Coll Cardiol , vol.55 , Issue.22 , pp. 2427-2434
    • Hochholzer, W.1    Trenk, D.2    Fromm, M.F.3
  • 177
    • 33745815689 scopus 로고    scopus 로고
    • Insulin therapy is associated with platelet dysfunction in patients with type 2 diabetes mellitus on dual oral antiplatelet treatment
    • Angiolillo DJ, Bernardo E, Ramirez C, et al. Insulin therapy is associated with platelet dysfunction in patients with type 2 diabetes mellitus on dual oral antiplatelet treatment. J Am Coll Cardiol 2006; 48(2): 298-304.
    • (2006) J Am Coll Cardiol , vol.48 , Issue.2 , pp. 298-304
    • Angiolillo, D.J.1    Bernardo, E.2    Ramirez, C.3
  • 178
    • 79961162495 scopus 로고    scopus 로고
    • Is platelet inhibition due to thienopyridines increased in elderly patients, in patients with previous stroke and patients with low body weight as a possible explanation of an increased bleeding risk?
    • Breet NJ, van Donkersgoed HE, van Werkum JW, et al. Is platelet inhibition due to thienopyridines increased in elderly patients, in patients with previous stroke and patients with low body weight as a possible explanation of an increased bleeding risk? Neth Heart J 2011; 19(6): 279-84.
    • (2011) Neth Heart J , vol.19 , Issue.6 , pp. 279-284
    • Breet, N.J.1    van Donkersgoed, H.E.2    van Werkum, J.W.3
  • 179
    • 80052200835 scopus 로고    scopus 로고
    • Relation of body mass index to on-treatment (clopidogrel + aspirin) platelet reactivity
    • Gaglia MA, Jr., Torguson R, Pakala R, et al. Relation of body mass index to on-treatment (clopidogrel + aspirin) platelet reactivity. Am J Cardiol 2011; 108(6): 766-71.
    • (2011) Am J Cardiol , vol.108 , Issue.6 , pp. 766-771
    • Gaglia Jr., M.A.1    Torguson, R.2    Pakala, R.3
  • 180
    • 0036624585 scopus 로고    scopus 로고
    • The smoker's paradox: Insights from the angiographic substudies of the TIMI trials
    • Angeja BG, Kermgard S, Chen MS, et al. The smoker's paradox: insights from the angiographic substudies of the TIMI trials. J Thromb Thrombolysis 2002; 13(3): 133-9.
    • (2002) J Thromb Thrombolysis , vol.13 , Issue.3 , pp. 133-139
    • Angeja, B.G.1    Kermgard, S.2    Chen, M.S.3
  • 181
    • 0033559791 scopus 로고    scopus 로고
    • Platelet spontaneous aggregation in platelet-rich plasma is increased in habitual smokers
    • Fusegawa Y, Goto S, Handa S, Kawada T, Ando Y. Platelet spontaneous aggregation in platelet-rich plasma is increased in habitual smokers. Thromb Res 1999; 93(6): 271-8.
    • (1999) Thromb Res , vol.93 , Issue.6 , pp. 271-278
    • Fusegawa, Y.1    Goto, S.2    Handa, S.3    Kawada, T.4    Ando, Y.5
  • 182
    • 23844442838 scopus 로고    scopus 로고
    • Contribution of cyclooxygenase-2 to elevated biosynthesis of thromboxane A2 and prostacyclin in cigarette smokers
    • McAdam BF, Byrne D, Morrow JD, Oates JA. Contribution of cyclooxygenase-2 to elevated biosynthesis of thromboxane A2 and prostacyclin in cigarette smokers. Circulation 2005; 112(7): 1024-9.
    • (2005) Circulation , vol.112 , Issue.7 , pp. 1024-1029
    • McAdam, B.F.1    Byrne, D.2    Morrow, J.D.3    Oates, J.A.4
  • 183
    • 19344362698 scopus 로고    scopus 로고
    • Cigarette smoking is associated with increased circulating proinflammatory and procoagulant markers in patients with chronic coronary artery disease: Effects of aspirin treatment
    • Ikonomidis I, Lekakis J, Vamvakou G, Andreotti F, Nihoyannopoulos P. Cigarette smoking is associated with increased circulating proinflammatory and procoagulant markers in patients with chronic coronary artery disease: effects of aspirin treatment. Am Heart J 2005; 149(5): 832-9.
    • (2005) Am Heart J , vol.149 , Issue.5 , pp. 832-839
    • Ikonomidis, I.1    Lekakis, J.2    Vamvakou, G.3    Andreotti, F.4    Nihoyannopoulos, P.5
  • 184
    • 55449132867 scopus 로고    scopus 로고
    • Incomplete inhibition of thromboxane biosynthesis by acetylsalicylic acid: Determinants and effect on cardiovascular risk
    • Eikelboom JW, Hankey GJ, Thom J, et al. Incomplete inhibition of thromboxane biosynthesis by acetylsalicylic acid: determinants and effect on cardiovascular risk. Circulation 2008; 118(17): 1705-12.
    • (2008) Circulation , vol.118 , Issue.17 , pp. 1705-1712
    • Eikelboom, J.W.1    Hankey, G.J.2    Thom, J.3
  • 185
    • 33747157718 scopus 로고    scopus 로고
    • Frequency of aspirin resistance in a community hospital
    • Mirkhel A, Peyster E, Sundeen J, et al. Frequency of aspirin resistance in a community hospital. Am J Cardiol 2006; 98(5): 577-9.
    • (2006) Am J Cardiol , vol.98 , Issue.5 , pp. 577-579
    • Mirkhel, A.1    Peyster, E.2    Sundeen, J.3
  • 186
    • 80052292634 scopus 로고    scopus 로고
    • Impact of smoking on antiplatelet effect of clopidogrel and prasugrel after loading dose and on maintenance therapy
    • Hochholzer W, Trenk D, Mega JL, et al. Impact of smoking on antiplatelet effect of clopidogrel and prasugrel after loading dose and on maintenance therapy. Am Heart J 2011; 162(3): 518-26.
    • (2011) Am Heart J , vol.162 , Issue.3 , pp. 518-526
    • Hochholzer, W.1    Trenk, D.2    Mega, J.L.3
  • 187
    • 37549006004 scopus 로고    scopus 로고
    • The Residual Platelet Aggregation after Deployment of Intracoronary Stent (PREDICT) score
    • Geisler T, Grass D, Bigalke B, et al. The Residual Platelet Aggregation after Deployment of Intracoronary Stent (PREDICT) score. J Thromb Haemost 2008; 6(1): 54-61.
    • (2008) J Thromb Haemost , vol.6 , Issue.1 , pp. 54-61
    • Geisler, T.1    Grass, D.2    Bigalke, B.3
  • 188
    • 48449101872 scopus 로고    scopus 로고
    • The association of cigarette smoking with enhanced platelet inhibition by clopidogrel
    • Bliden KP, DiChiara J, Lawal L, et al. The association of cigarette smoking with enhanced platelet inhibition by clopidogrel. J Am Coll Cardiol 2008; 52(7): 531-3.
    • (2008) J Am Coll Cardiol , vol.52 , Issue.7 , pp. 531-533
    • Bliden, K.P.1    Dichiara, J.2    Lawal, L.3
  • 189
    • 70349868299 scopus 로고    scopus 로고
    • Smoking promotes clopidogrel-mediated platelet inhibition in patients receiving dual antiplatelet therapy
    • Gremmel T, Steiner S, Seidinger D, Koppensteiner R, Panzer S, Kopp CW. Smoking promotes clopidogrel-mediated platelet inhibition in patients receiving dual antiplatelet therapy. Thromb Res 2009; 124(5): 588-91.
    • (2009) Thromb Res , vol.124 , Issue.5 , pp. 588-591
    • Gremmel, T.1    Steiner, S.2    Seidinger, D.3    Koppensteiner, R.4    Panzer, S.5    Kopp, C.W.6
  • 190
    • 84861386102 scopus 로고    scopus 로고
    • High on-thienopyridine platelet reactivity in elderly coronary patients: The SENIOR-PLATELET study
    • May
    • Silvain J, Cayla G, Hulot JS, et al. High on-thienopyridine platelet reactivity in elderly coronary patients: the SENIOR-PLATELET study. Eur Heart J. 2012 May;33(10):1241-9.
    • (2012) Eur Heart J , vol.33 , Issue.10 , pp. 1241-1249
    • Silvain, J.1    Cayla, G.2    Hulot, J.S.3
  • 191
    • 73449139419 scopus 로고    scopus 로고
    • Smoking, clopidogrel, and mortality in patients with established cardiovascular disease
    • Berger JS, Bhatt DL, Steinhubl SR, et al. Smoking, clopidogrel, and mortality in patients with established cardiovascular disease. Circulation 2009; 120(23): 2337-44.
    • (2009) Circulation , vol.120 , Issue.23 , pp. 2337-2344
    • Berger, J.S.1    Bhatt, D.L.2    Steinhubl, S.R.3
  • 192
    • 63549115843 scopus 로고    scopus 로고
    • Interaction between cigarette smoking and clinical benefit of clopidogrel
    • Desai NR, Mega JL, Jiang S, Cannon CP, Sabatine MS. Interaction between cigarette smoking and clinical benefit of clopidogrel. J Am Coll Cardiol 2009; 53(15): 1273-8.
    • (2009) J Am Coll Cardiol , vol.53 , Issue.15 , pp. 1273-1278
    • Desai, N.R.1    Mega, J.L.2    Jiang, S.3    Cannon, C.P.4    Sabatine, M.S.5
  • 193
    • 0034611780 scopus 로고    scopus 로고
    • Coronary heart disease in patients with diabetes
    • Haffner SM. Coronary heart disease in patients with diabetes. N Engl J Med 2000; 342(14): 1040-2.
    • (2000) N Engl J Med , vol.342 , Issue.14 , pp. 1040-1042
    • Haffner, S.M.1
  • 194
    • 0032560807 scopus 로고    scopus 로고
    • Mortality from coronary heart disease in subjects with type 2 diabetes and in nondiabetic subjects with and without prior myocardial infarction
    • Haffner SM, Lehto S, Ronnemaa T, Pyorala K, Laakso M. Mortality from coronary heart disease in subjects with type 2 diabetes and in nondiabetic subjects with and without prior myocardial infarction. N Engl J Med 1998; 339(4): 229-34.
    • (1998) N Engl J Med , vol.339 , Issue.4 , pp. 229-234
    • Haffner, S.M.1    Lehto, S.2    Ronnemaa, T.3    Pyorala, K.4    Laakso, M.5
  • 195
    • 55949127696 scopus 로고    scopus 로고
    • The prevention of progression of arterial disease and diabetes (POPADAD) trial: Factorial randomised placebo controlled trial of aspirin and antioxidants in patients with diabetes and asymptomatic peripheral arterial disease
    • Belch J, MacCuish A, Campbell I, et al. The prevention of progression of arterial disease and diabetes (POPADAD) trial: factorial randomised placebo controlled trial of aspirin and antioxidants in patients with diabetes and asymptomatic peripheral arterial disease. BMJ 2008; 337: a1840.
    • (2008) BMJ , vol.337
    • Belch, J.1    Maccuish, A.2    Campbell, I.3
  • 196
    • 56149113603 scopus 로고    scopus 로고
    • Low-dose aspirin for primary prevention of atherosclerotic events in patients with type 2 diabetes: A randomized controlled trial
    • Ogawa H, Nakayama M, Morimoto T, et al. Low-dose aspirin for primary prevention of atherosclerotic events in patients with type 2 diabetes: a randomized controlled trial. JAMA 2008; 300(18): 2134-41.
    • (2008) JAMA , vol.300 , Issue.18 , pp. 2134-2141
    • Ogawa, H.1    Nakayama, M.2    Morimoto, T.3
  • 197
    • 34250762573 scopus 로고    scopus 로고
    • High levels of low-density lipoprotein cholesterol and triglycerides and suboptimal glycemic control predict diminished ex vivo aspirin responsiveness in patients with Type 2 diabetes
    • Hovens MM, Snoep JD, Groeneveld Y, Tamsma JT, Eikenboom JC, Huisman MV. High levels of low-density lipoprotein cholesterol and triglycerides and suboptimal glycemic control predict diminished ex vivo aspirin responsiveness in patients with Type 2 diabetes. J Thromb Haemost 2007; 5(7): 1562-4.
    • (2007) J Thromb Haemost , vol.5 , Issue.7 , pp. 1562-1564
    • Hovens, M.M.1    Snoep, J.D.2    Groeneveld, Y.3    Tamsma, J.T.4    Eikenboom, J.C.5    Huisman, M.V.6
  • 198
    • 77957113521 scopus 로고    scopus 로고
    • Reduced platelet response to aspirin in patients with coronary artery disease and type 2 diabetes mellitus
    • Mortensen SB, Larsen SB, Grove EL, Kristensen SD, Hvas AM. Reduced platelet response to aspirin in patients with coronary artery disease and type 2 diabetes mellitus. Thromb Res 2010; 126(4): 318-22.
    • (2010) Thromb Res , vol.126 , Issue.4 , pp. 318-322
    • Mortensen, S.B.1    Larsen, S.B.2    Grove, E.L.3    Kristensen, S.D.4    Hvas, A.M.5
  • 200
    • 21144451858 scopus 로고    scopus 로고
    • Prevalence of aspirin resistance in patients with type 2 diabetes
    • Fateh-Moghadam S, Plockinger U, Cabeza N, et al. Prevalence of aspirin resistance in patients with type 2 diabetes. Acta Diabetol 2005; 42(2): 99-103.
    • (2005) Acta Diabetol , vol.42 , Issue.2 , pp. 99-103
    • Fateh-Moghadam, S.1    Plockinger, U.2    Cabeza, N.3
  • 201
    • 79952168736 scopus 로고    scopus 로고
    • Diabetes and antiplatelet therapy in acute coronary syndrome
    • Ferreiro JL, Angiolillo DJ. Diabetes and antiplatelet therapy in acute coronary syndrome. Circulation 2011; 123(7): 798-813.
    • (2011) Circulation , vol.123 , Issue.7 , pp. 798-813
    • Ferreiro, J.L.1    Angiolillo, D.J.2
  • 202
    • 84859179601 scopus 로고    scopus 로고
    • The influence of aspirin dose and glycemic control on platelet inhibition in patients with type 2 diabetes mellitus
    • Apr
    • Lemkes BA, Bahler L, Kamphuisen PW, et al. The influence of aspirin dose and glycemic control on platelet inhibition in patients with type 2 diabetes mellitus. J Thromb Haemost. 2012 Apr;10(4):639-46.
    • (2012) J Thromb Haemost , vol.10 , Issue.4 , pp. 639-646
    • Lemkes, B.A.1    Bahler, L.2    Kamphuisen, P.W.3
  • 203
    • 79955155110 scopus 로고    scopus 로고
    • Effects of intensive glucose control on platelet reactivity in patients with acute coronary syndromes. Results of the CHIPS Study (Control de Hiperglucemia y Actividad Plaquetaria en Pacientes con Sindrome Coronario Agudo)
    • Vivas D, Garcia-Rubira JC, Bernardo E, et al. Effects of intensive glucose control on platelet reactivity in patients with acute coronary syndromes. Results of the CHIPS Study (Control de Hiperglucemia y Actividad Plaquetaria en Pacientes con Sindrome Coronario Agudo). Heart 2011; 97(10): 803-9.
    • (2011) Heart , vol.97 , Issue.10 , pp. 803-809
    • Vivas, D.1    Garcia-Rubira, J.C.2    Bernardo, E.3
  • 204
    • 2642522886 scopus 로고    scopus 로고
    • Soluble CD40 ligand, soluble Pselectin, interleukin-6, and tissue factor in diabetes mellitus: Relationships to cardiovascular disease and risk factor intervention
    • Lim HS, Blann AD, Lip GY. Soluble CD40 ligand, soluble Pselectin, interleukin-6, and tissue factor in diabetes mellitus: relationships to cardiovascular disease and risk factor intervention. Circulation 2004; 109(21): 2524-8.
    • (2004) Circulation , vol.109 , Issue.21 , pp. 2524-2528
    • Lim, H.S.1    Blann, A.D.2    Lip, G.Y.3
  • 205
  • 206
    • 0025214340 scopus 로고
    • Evidence for abnormal platelet glycoprotein expression in diabetes mellitus
    • Tschoepe D, Roesen P, Kaufmann L, et al. Evidence for abnormal platelet glycoprotein expression in diabetes mellitus. Eur J Clin Invest 1990; 20(2): 166-70.
    • (1990) Eur J Clin Invest , vol.20 , Issue.2 , pp. 166-170
    • Tschoepe, D.1    Roesen, P.2    Kaufmann, L.3
  • 207
    • 0032212359 scopus 로고    scopus 로고
    • Better increase in fibrin gel porosity by low dose than intermediate dose acetylsalicylic acid
    • Williams S, Fatah K, Hjemdahl P, Blomback M. Better increase in fibrin gel porosity by low dose than intermediate dose acetylsalicylic acid. Eur Heart J 1998; 19(11): 1666-72.
    • (1998) Eur Heart J , vol.19 , Issue.11 , pp. 1666-1672
    • Williams, S.1    Fatah, K.2    Hjemdahl, P.3    Blomback, M.4
  • 208
    • 33947266124 scopus 로고    scopus 로고
    • Antithrombotic properties of aspirin and resistance to aspirin: Beyond strictly antiplatelet actions
    • Undas A, Brummel-Ziedins KE, Mann KG. Antithrombotic properties of aspirin and resistance to aspirin: beyond strictly antiplatelet actions. Blood 2007; 109(6): 2285-92.
    • (2007) Blood , vol.109 , Issue.6 , pp. 2285-2292
    • Undas, A.1    Brummel-Ziedins, K.E.2    Mann, K.G.3
  • 209
    • 11944265051 scopus 로고
    • Hyperfibrinogenemia. An important risk factor for vascular complications in diabetes
    • Ganda OP, Arkin CF. Hyperfibrinogenemia. An important risk factor for vascular complications in diabetes. Diabetes Care 1992; 15(10): 1245-50.
    • (1992) Diabetes Care , vol.15 , Issue.10 , pp. 1245-1250
    • Ganda, O.P.1    Arkin, C.F.2
  • 210
    • 33646428125 scopus 로고    scopus 로고
    • Molecular mechanisms involved in the resistance of fibrin to clot lysis by plasmin in subjects with type 2 diabetes mellitus
    • Dunn EJ, Philippou H, Ariens RA, Grant PJ. Molecular mechanisms involved in the resistance of fibrin to clot lysis by plasmin in subjects with type 2 diabetes mellitus. Diabetologia 2006; 49(5): 1071-80.
    • (2006) Diabetologia , vol.49 , Issue.5 , pp. 1071-1080
    • Dunn, E.J.1    Philippou, H.2    Ariens, R.A.3    Grant, P.J.4
  • 211
    • 84859079192 scopus 로고    scopus 로고
    • High-Dose Aspirin Is Required to Influence Plasma Fibrin Network Structure in Patients With Type 1 Diabetes
    • Tehrani S, Antovic A, Mobarrez F, et al. High-Dose Aspirin Is Required to Influence Plasma Fibrin Network Structure in Patients With Type 1 Diabetes. Diabetes Care 2012; 35(2): 404-8.
    • (2012) Diabetes Care , vol.35 , Issue.2 , pp. 404-408
    • Tehrani, S.1    Antovic, A.2    Mobarrez, F.3
  • 212
    • 30344483664 scopus 로고    scopus 로고
    • Thromboxane-dependent CD40 ligand release in type 2 diabetes mellitus
    • Santilli F, Davi G, Consoli A, et al. Thromboxane-dependent CD40 ligand release in type 2 diabetes mellitus. J Am Coll Cardiol 2006; 47(2): 391-7.
    • (2006) J Am Coll Cardiol , vol.47 , Issue.2 , pp. 391-397
    • Santilli, F.1    Davi, G.2    Consoli, A.3
  • 213
    • 35248878504 scopus 로고    scopus 로고
    • Residual platelet reactivity is associated with clinical and laboratory characteristics in patients with ischemic heart disease undergoing PCI on dual antiplatelet therapy
    • Marcucci R, Gori AM, Paniccia R, et al. Residual platelet reactivity is associated with clinical and laboratory characteristics in patients with ischemic heart disease undergoing PCI on dual antiplatelet therapy. Atherosclerosis 2007; 195(1): e217-e223.
    • (2007) Atherosclerosis , vol.195 , Issue.1
    • Marcucci, R.1    Gori, A.M.2    Paniccia, R.3
  • 214
    • 33846656039 scopus 로고    scopus 로고
    • Platelet response to clopidogrel is attenuated in diabetic patients undergoing coronary stent implantation
    • Geisler T, Anders N, Paterok M, et al. Platelet response to clopidogrel is attenuated in diabetic patients undergoing coronary stent implantation. Diabetes Care 2007; 30(2): 372-4.
    • (2007) Diabetes Care , vol.30 , Issue.2 , pp. 372-374
    • Geisler, T.1    Anders, N.2    Paterok, M.3
  • 215
    • 79952165871 scopus 로고    scopus 로고
    • Functional profile of the platelet P2Y receptor signalling pathway in patients with type 2 diabetes mellitus and coronary artery disease
    • Ueno M, Ferreiro JL, Tomasello SD, et al. Functional profile of the platelet P2Y receptor signalling pathway in patients with type 2 diabetes mellitus and coronary artery disease. Thromb Haemost 2011; 105(4): 730-2.
    • (2011) Thromb Haemost , vol.105 , Issue.4 , pp. 730-732
    • Ueno, M.1    Ferreiro, J.L.2    Tomasello, S.D.3
  • 216
    • 84856639596 scopus 로고    scopus 로고
    • Contemporary use of glycoprotein IIb/IIIa inhibitors
    • Kristensen SD, Wurtz M, Grove EL, et al. Contemporary use of glycoprotein IIb/IIIa inhibitors. Thromb Haemost 2012; 107(2): 215-24.
    • (2012) Thromb Haemost , vol.107 , Issue.2 , pp. 215-224
    • Kristensen, S.D.1    Wurtz, M.2    Grove, E.L.3
  • 217
    • 77954087762 scopus 로고    scopus 로고
    • Aspirin for primary prevention of cardiovascular events in people with diabetes: A position statement of the American Diabetes Association, a scientific statement of the American Heart Association, and an expert consensus document of the American College of Cardiology Foundation
    • Pignone M, Alberts MJ, Colwell JA, et al. Aspirin for primary prevention of cardiovascular events in people with diabetes: a position statement of the American Diabetes Association, a scientific statement of the American Heart Association, and an expert consensus document of the American College of Cardiology Foundation. Circulation 2010; 121(24): 2694-701.
    • (2010) Circulation , vol.121 , Issue.24 , pp. 2694-2701
    • Pignone, M.1    Alberts, M.J.2    Colwell, J.A.3
  • 218
    • 85047677426 scopus 로고
    • Differences in bleeding time, aspirin sensitivity and adrenaline between acute myocardial infarction and unstable angina
    • Kristensen SD, Bath PM, Martin JF. Differences in bleeding time, aspirin sensitivity and adrenaline between acute myocardial infarction and unstable angina. Cardiovasc Res 1990; 24(1): 19-23.
    • (1990) Cardiovasc Res , vol.24 , Issue.1 , pp. 19-23
    • Kristensen, S.D.1    Bath, P.M.2    Martin, J.F.3
  • 219
    • 0020612601 scopus 로고
    • Changes in volume and density of platelets in myocardial infarction
    • Aug 13
    • Martin JF, Plumb J, Kilbey RS, Kishk YT. Changes in volume and density of platelets in myocardial infarction. Br Med J (Clin Res Ed) 1983 Aug 13; 287(6390): 456-9.
    • (1983) Br Med J (Clin Res Ed) , vol.287 , Issue.6390 , pp. 456-459
    • Martin, J.F.1    Plumb, J.2    Kilbey, R.S.3    Kishk, Y.T.4
  • 221
    • 20344408497 scopus 로고    scopus 로고
    • Stent thrombosis is associated with an impaired response to antiplatelet therapy
    • Wenaweser P, Dorffler-Melly J, Imboden K, et al. Stent thrombosis is associated with an impaired response to antiplatelet therapy. J Am Coll Cardiol 2005; 45(11): 1748-52.
    • (2005) J Am Coll Cardiol , vol.45 , Issue.11 , pp. 1748-1752
    • Wenaweser, P.1    Dorffler-Melly, J.2    Imboden, K.3
  • 222
    • 35048901889 scopus 로고    scopus 로고
    • Residual platelet reactivity is an independent predictor of myocardial injury in acute myocardial infarction patients on antiaggregant therapy
    • Marcucci R, Paniccia R, Antonucci E, et al. Residual platelet reactivity is an independent predictor of myocardial injury in acute myocardial infarction patients on antiaggregant therapy. Thromb Haemost 2007; 98(4): 844-51.
    • (2007) Thromb Haemost , vol.98 , Issue.4 , pp. 844-851
    • Marcucci, R.1    Paniccia, R.2    Antonucci, E.3
  • 223
    • 34447639423 scopus 로고    scopus 로고
    • Variation and importance of aspirin resistance in patients with known cardiovascular disease
    • Poulsen TS, Kristensen SR, Korsholm L, et al. Variation and importance of aspirin resistance in patients with known cardiovascular disease. Thromb Res 2007; 120(4): 477-84.
    • (2007) Thromb Res , vol.120 , Issue.4 , pp. 477-484
    • Poulsen, T.S.1    Kristensen, S.R.2    Korsholm, L.3
  • 224
    • 33847229876 scopus 로고    scopus 로고
    • Prevalence of aspirin resistance in patients with an evolving acute myocardial infarction
    • Poulsen TS, Jorgensen B, Korsholm L, Bjorn LP, Haghfelt T, Mickley H. Prevalence of aspirin resistance in patients with an evolving acute myocardial infarction. Thromb Res 2007; 119(5): 555-62.
    • (2007) Thromb Res , vol.119 , Issue.5 , pp. 555-562
    • Poulsen, T.S.1    Jorgensen, B.2    Korsholm, L.3    Bjorn, L.P.4    Haghfelt, T.5    Mickley, H.6
  • 225
    • 33845703949 scopus 로고    scopus 로고
    • Partial inhibition of platelet thromboxane A2 synthesis by aspirin is associated with myonecrosis in patients with ST-segment elevation myocardial infarction
    • Valles J, Santos MT, Fuset MP, et al. Partial inhibition of platelet thromboxane A2 synthesis by aspirin is associated with myonecrosis in patients with ST-segment elevation myocardial infarction. Am J Cardiol 2007; 99(1): 19-25.
    • (2007) Am J Cardiol , vol.99 , Issue.1 , pp. 19-25
    • Valles, J.1    Santos, M.T.2    Fuset, M.P.3
  • 226
    • 80053976156 scopus 로고    scopus 로고
    • Clinical and Prognostic Implications of the Initial Response to Aspirin in Patients With Acute Coronary Syndrome
    • Spectre G, Mosseri M, Abdelrahman NM, et al. Clinical and Prognostic Implications of the Initial Response to Aspirin in Patients With Acute Coronary Syndrome. Am J Cardiol 2011; 108(8): 1112-8.
    • (2011) Am J Cardiol , vol.108 , Issue.8 , pp. 1112-1118
    • Spectre, G.1    Mosseri, M.2    Abdelrahman, N.M.3
  • 227
    • 27444431936 scopus 로고    scopus 로고
    • Resistance to aspirin is increased by ST-elevation myocardial infarction and correlates with adenosine diphosphate levels
    • Borna C, Lazarowski E, van HC, Ohlin H, Erlinge D. Resistance to aspirin is increased by ST-elevation myocardial infarction and correlates with adenosine diphosphate levels. Thromb J 2005; 3: 10.
    • (2005) Thromb J , vol.3 , pp. 10
    • Borna, C.1    Lazarowski, E.2    van, H.C.3    Ohlin, H.4    Erlinge, D.5
  • 228
    • 49349114160 scopus 로고    scopus 로고
    • Incidence and clinical impact of dual nonresponsiveness to aspirin and clopidogrel in patients with drug-eluting stents
    • Gori AM, Marcucci R, Migliorini A, et al. Incidence and clinical impact of dual nonresponsiveness to aspirin and clopidogrel in patients with drug-eluting stents. J Am Coll Cardiol 2008; 52(9): 734-9.
    • (2008) J Am Coll Cardiol , vol.52 , Issue.9 , pp. 734-739
    • Gori, A.M.1    Marcucci, R.2    Migliorini, A.3
  • 229
    • 44349185490 scopus 로고    scopus 로고
    • Residual platelet activity is increased in clopidogreland ASA-treated patients with coronary stenting for acute coronary syndromes compared with stable coronary artery disease
    • Geisler T, Kapp M, Gohring-Frischholz K, et al. Residual platelet activity is increased in clopidogreland ASA-treated patients with coronary stenting for acute coronary syndromes compared with stable coronary artery disease. Heart 2008; 94(6): 743-7.
    • (2008) Heart , vol.94 , Issue.6 , pp. 743-747
    • Geisler, T.1    Kapp, M.2    Gohring-Frischholz, K.3
  • 230
    • 0038300483 scopus 로고    scopus 로고
    • Impact of angina class on inhibition of platelet aggregation following clopidogrel loading in patients undergoing coronary intervention: Do we need more aggressive dosing regimens in unstable angina?
    • Soffer D, Moussa I, Harjai KJ, et al. Impact of angina class on inhibition of platelet aggregation following clopidogrel loading in patients undergoing coronary intervention: do we need more aggressive dosing regimens in unstable angina? Catheter Cardiovasc Interv 2003; 59(1): 21-5.
    • (2003) Catheter Cardiovasc Interv , vol.59 , Issue.1 , pp. 21-25
    • Soffer, D.1    Moussa, I.2    Harjai, K.J.3
  • 231
    • 0019471204 scopus 로고
    • Drug response in the elderly--sensitivity and pharmacokinetic considerations
    • Crooks J, Stevenson IH. Drug response in the elderly--sensitivity and pharmacokinetic considerations. Age Ageing 1981; 10(2): 73-80.
    • (1981) Age Ageing , vol.10 , Issue.2 , pp. 73-80
    • Crooks, J.1    Stevenson, I.H.2
  • 232
    • 33750996725 scopus 로고    scopus 로고
    • Hemostasis and aging
    • Franchini M. Hemostasis and aging. Crit Rev Oncol Hematol 2006; 60(2): 144-51.
    • (2006) Crit Rev Oncol Hematol , vol.60 , Issue.2 , pp. 144-151
    • Franchini, M.1
  • 233
    • 78349301230 scopus 로고    scopus 로고
    • Antithrombotic therapy in the elderly
    • Capodanno D, Angiolillo DJ. Antithrombotic therapy in the elderly. J Am Coll Cardiol 2010; 56(21): 1683-92.
    • (2010) J Am Coll Cardiol , vol.56 , Issue.21 , pp. 1683-1692
    • Capodanno, D.1    Angiolillo, D.J.2
  • 234
    • 0035421783 scopus 로고    scopus 로고
    • Profile and prevalence of aspirin resistance in patients with cardiovascular disease
    • Gum PA, Kottke-Marchant K, Poggio ED, et al. Profile and prevalence of aspirin resistance in patients with cardiovascular disease. Am J Cardiol 2001; 88(3): 230-5.
    • (2001) Am J Cardiol , vol.88 , Issue.3 , pp. 230-235
    • Gum, P.A.1    Kottke-Marchant, K.2    Poggio, E.D.3
  • 235
    • 79952598836 scopus 로고    scopus 로고
    • Standardvs high-dose clopidogrel based on platelet function testing after percutaneous coronary intervention: The GRAVITAS randomized trial
    • Price MJ, Berger PB, Teirstein PS, et al. Standardvs high-dose clopidogrel based on platelet function testing after percutaneous coronary intervention: the GRAVITAS randomized trial. JAMA 2011; 305(11): 1097-105.
    • (2011) JAMA , vol.305 , Issue.11 , pp. 1097-1105
    • Price, M.J.1    Berger, P.B.2    Teirstein, P.S.3
  • 236
    • 84863285492 scopus 로고    scopus 로고
    • Platelet biology and response to antiplatelet therapy in women: Implications for the development and use of antiplatelet pharmacotherapies for cardiovascular disease
    • Wang TY, Angiolillo DJ, Cushman M, et al. Platelet biology and response to antiplatelet therapy in women: implications for the development and use of antiplatelet pharmacotherapies for cardiovascular disease. J Am Coll Cardiol 2012; 59(10): 891-900.
    • (2012) J Am Coll Cardiol , vol.59 , Issue.10 , pp. 891-900
    • Wang, T.Y.1    Angiolillo, D.J.2    Cushman, M.3
  • 238
  • 239
    • 0018138512 scopus 로고
    • A randomized trial of aspirin and sulfinpyrazone in threatened stroke
    • The Canadian Cooperative Study Group
    • The Canadian Cooperative Study Group. A randomized trial of aspirin and sulfinpyrazone in threatened stroke. N Engl J Med 1978; 299(2): 53-9.
    • (1978) N Engl J Med , vol.299 , Issue.2 , pp. 53-59
  • 240
    • 0022906322 scopus 로고
    • Sex-related differences in the effects of aspirin on the interaction of platelets with subendothelium
    • Escolar G, Bastida E, Garrido M, Rodriguez-Gomez J, Castillo R, Ordinas A. Sex-related differences in the effects of aspirin on the interaction of platelets with subendothelium. Thromb Res 1986; 44(6): 837-47.
    • (1986) Thromb Res , vol.44 , Issue.6 , pp. 837-847
    • Escolar, G.1    Bastida, E.2    Garrido, M.3    Rodriguez-Gomez, J.4    Castillo, R.5    Ordinas, A.6
  • 241
    • 15744394416 scopus 로고    scopus 로고
    • The puzzle of aspirin and sex
    • Levin RI. The puzzle of aspirin and sex. N Engl J Med 2005; 352(13): 1366-8.
    • (2005) N Engl J Med , vol.352 , Issue.13 , pp. 1366-1368
    • Levin, R.I.1
  • 242
    • 30944467297 scopus 로고    scopus 로고
    • Aspirin for the primary prevention of cardiovascular events in women and men: A sex-specific meta-analysis of randomized controlled trials
    • Berger JS, Roncaglioni MC, Avanzini F, Pangrazzi I, Tognoni G, Brown DL. Aspirin for the primary prevention of cardiovascular events in women and men: a sex-specific meta-analysis of randomized controlled trials. JAMA 2006; 295(3): 306-13.
    • (2006) JAMA , vol.295 , Issue.3 , pp. 306-313
    • Berger, J.S.1    Roncaglioni, M.C.2    Avanzini, F.3    Pangrazzi, I.4    Tognoni, G.5    Brown, D.L.6
  • 243
    • 70350711675 scopus 로고    scopus 로고
    • The relative efficacy and safety of clopidogrel in women and men a sex-specific collaborative meta-analysis
    • Berger JS, Bhatt DL, Cannon CP, et al. The relative efficacy and safety of clopidogrel in women and men a sex-specific collaborative meta-analysis. J Am Coll Cardiol 2009; 54(21): 1935-45.
    • (2009) J Am Coll Cardiol , vol.54 , Issue.21 , pp. 1935-1945
    • Berger, J.S.1    Bhatt, D.L.2    Cannon, C.P.3
  • 244
    • 33645063230 scopus 로고    scopus 로고
    • Sex differences in platelet reactivity and response to low-dose aspirin therapy
    • Becker DM, Segal J, Vaidya D, et al. Sex differences in platelet reactivity and response to low-dose aspirin therapy. JAMA 2006; 295(12): 1420-7.
    • (2006) JAMA , vol.295 , Issue.12 , pp. 1420-1427
    • Becker, D.M.1    Segal, J.2    Vaidya, D.3
  • 245
    • 43049107140 scopus 로고    scopus 로고
    • Platelet inhibition by aspirin 81 and 325 mg/day in men versus women without clinically apparent cardiovascular disease
    • Qayyum R, Becker DM, Yanek LR, et al. Platelet inhibition by aspirin 81 and 325 mg/day in men versus women without clinically apparent cardiovascular disease. Am J Cardiol 2008; 101(9): 1359-63.
    • (2008) Am J Cardiol , vol.101 , Issue.9 , pp. 1359-1363
    • Qayyum, R.1    Becker, D.M.2    Yanek, L.R.3
  • 246
    • 0024552324 scopus 로고
    • Sex difference in antithrombotic effect of aspirin
    • Spranger M, Aspey BS, Harrison MJ. Sex difference in antithrombotic effect of aspirin. Stroke 1989; 20(1): 34-7.
    • (1989) Stroke , vol.20 , Issue.1 , pp. 34-37
    • Spranger, M.1    Aspey, B.S.2    Harrison, M.J.3
  • 247
    • 0021026032 scopus 로고
    • A sex difference in the effect of aspirin on spontaneous platelet aggregation in whole blood
    • Harrison MJ, Weisblatt E. A sex difference in the effect of aspirin on spontaneous platelet aggregation in whole blood. Thromb Haemost 1983; 50(4): 773-4.
    • (1983) Thromb Haemost , vol.50 , Issue.4 , pp. 773-774
    • Harrison, M.J.1    Weisblatt, E.2
  • 248
    • 0022222072 scopus 로고
    • The effects of age and sex on the disposition of acetylsalicylic acid and its metabolites
    • Ho PC, Triggs EJ, Bourne DW, Heazlewood VJ. The effects of age and sex on the disposition of acetylsalicylic acid and its metabolites. Br J Clin Pharmacol 1985; 19(5): 675-84.
    • (1985) Br J Clin Pharmacol , vol.19 , Issue.5 , pp. 675-684
    • Ho, P.C.1    Triggs, E.J.2    Bourne, D.W.3    Heazlewood, V.J.4
  • 250
    • 0016440823 scopus 로고
    • Sex and age differences in human platelet aggregation
    • Johnson M, Ramey E, Ramwell PW. Sex and age differences in human platelet aggregation. Nature 1975; 253(5490): 355-7.
    • (1975) Nature , vol.253 , Issue.5490 , pp. 355-357
    • Johnson, M.1    Ramey, E.2    Ramwell, P.W.3
  • 251
    • 84862778897 scopus 로고    scopus 로고
    • Inheritance of coronary artery disease in men: An analysis of the role of the Y chromosome
    • Charchar FJ, Bloomer LD, Barnes TA, et al. Inheritance of coronary artery disease in men: an analysis of the role of the Y chromosome. Lancet 2012; 379(9819): 915-22.
    • (2012) Lancet , vol.379 , Issue.9819 , pp. 915-922
    • Charchar, F.J.1    Bloomer, L.D.2    Barnes, T.A.3
  • 252
    • 25844458971 scopus 로고    scopus 로고
    • Femalespecific aspects in the pharmacotherapy of chronic cardiovascular diseases
    • Jochmann N, Stangl K, Garbe E, Baumann G, Stangl V. Femalespecific aspects in the pharmacotherapy of chronic cardiovascular diseases. Eur Heart J 2005; 26(16): 1585-95.
    • (2005) Eur Heart J , vol.26 , Issue.16 , pp. 1585-1595
    • Jochmann, N.1    Stangl, K.2    Garbe, E.3    Baumann, G.4    Stangl, V.5
  • 253
    • 70449469403 scopus 로고    scopus 로고
    • Gender and responses to aspirin and clopidogrel: Insights using short thrombelastography
    • Hobson AR, Qureshi Z, Banks P, Curzen N. Gender and responses to aspirin and clopidogrel: insights using short thrombelastography. Cardiovasc Ther 2009; 27(4): 246-52.
    • (2009) Cardiovasc Ther , vol.27 , Issue.4 , pp. 246-252
    • Hobson, A.R.1    Qureshi, Z.2    Banks, P.3    Curzen, N.4
  • 254
    • 0141468244 scopus 로고    scopus 로고
    • Kidney disease as a risk factor for development of cardiovascular disease: A statement from the American Heart Association Councils on Kidney in Cardiovascular Disease, High Blood Pressure Research, Clinical Cardiology, and Epidemiology and Prevention
    • Sarnak MJ, Levey AS, Schoolwerth AC, et al. Kidney disease as a risk factor for development of cardiovascular disease: a statement from the American Heart Association Councils on Kidney in Cardiovascular Disease, High Blood Pressure Research, Clinical Cardiology, and Epidemiology and Prevention. Circulation 2003; 108(17): 2154-69.
    • (2003) Circulation , vol.108 , Issue.17 , pp. 2154-2169
    • Sarnak, M.J.1    Levey, A.S.2    Schoolwerth, A.C.3
  • 255
    • 4644221457 scopus 로고    scopus 로고
    • Chronic kidney disease and the risks of death, cardiovascular events, and hospitalization
    • Go AS, Chertow GM, Fan D, McCulloch CE, Hsu CY. Chronic kidney disease and the risks of death, cardiovascular events, and hospitalization. N Engl J Med 2004; 351(13): 1296-305.
    • (2004) N Engl J Med , vol.351 , Issue.13 , pp. 1296-1305
    • Go, A.S.1    Chertow, G.M.2    Fan, D.3    McCulloch, C.E.4    Hsu, C.Y.5
  • 256
    • 0037012408 scopus 로고    scopus 로고
    • The impact of renal insufficiency on clinical outcomes in patients undergoing percutaneous coronary interventions
    • Best PJ, Lennon R, Ting HH, et al. The impact of renal insufficiency on clinical outcomes in patients undergoing percutaneous coronary interventions. J Am Coll Cardiol 2002; 39(7): 1113-9.
    • (2002) J Am Coll Cardiol , vol.39 , Issue.7 , pp. 1113-1119
    • Best, P.J.1    Lennon, R.2    Ting, H.H.3
  • 258
    • 84858333752 scopus 로고    scopus 로고
    • Influence of renal function and platelet turnover on the antiplatelet effect of aspirin
    • Wurtz M, Wulff LN, Grove EL, Kristensen SD, Hvas AM. Influence of renal function and platelet turnover on the antiplatelet effect of aspirin. Thromb Res 2012; 129(4): 434-40.
    • (2012) Thromb Res , vol.129 , Issue.4 , pp. 434-440
    • Wurtz, M.1    Wulff, L.N.2    Grove, E.L.3    Kristensen, S.D.4    Hvas, A.M.5
  • 260
    • 84858745342 scopus 로고    scopus 로고
    • High frequency of aspirin resistance in patients with nephrotic syndrome
    • Akoglu H, Agbaht K, Piskinpasa S, et al. High frequency of aspirin resistance in patients with nephrotic syndrome. Nephrol Dial Transplant 2012; 27(4): 1460-6.
    • (2012) Nephrol Dial Transplant , vol.27 , Issue.4 , pp. 1460-1466
    • Akoglu, H.1    Agbaht, K.2    Piskinpasa, S.3
  • 261
    • 40849083770 scopus 로고    scopus 로고
    • The efficacy and safety of shortand long-term dual antiplatelet therapy in patients with mild or moderate chronic kidney disease: Results from the Clopidogrel for the Reduction of Events During Observation (CREDO) trial
    • Best PJ, Steinhubl SR, Berger PB, et al. The efficacy and safety of shortand long-term dual antiplatelet therapy in patients with mild or moderate chronic kidney disease: results from the Clopidogrel for the Reduction of Events During Observation (CREDO) trial. Am Heart J 2008; 155(4): 687-93.
    • (2008) Am Heart J , vol.155 , Issue.4 , pp. 687-693
    • Best, P.J.1    Steinhubl, S.R.2    Berger, P.B.3
  • 262
    • 65449184492 scopus 로고    scopus 로고
    • Clinical outcomes of patients with diabetic nephropathy randomized to clopidogrel plus aspirin versus aspirin alone (a post hoc analysis of the clopidogrel for high atherothrombotic risk and ischemic stabilization, management, and avoidance [CHARISMA] trial)
    • Dasgupta A, Steinhubl SR, Bhatt DL, et al. Clinical outcomes of patients with diabetic nephropathy randomized to clopidogrel plus aspirin versus aspirin alone (a post hoc analysis of the clopidogrel for high atherothrombotic risk and ischemic stabilization, management, and avoidance [CHARISMA] trial). Am J Cardiol 2009; 103(10): 1359-63.
    • (2009) Am J Cardiol , vol.103 , Issue.10 , pp. 1359-1363
    • Dasgupta, A.1    Steinhubl, S.R.2    Bhatt, D.L.3
  • 263
    • 71749116951 scopus 로고    scopus 로고
    • A comparison of clopidogrel responsiveness in patients with versus without chronic renal failure
    • Park SH, Kim W, Park CS, Kang WY, Hwang SH, Kim W. A comparison of clopidogrel responsiveness in patients with versus without chronic renal failure. Am J Cardiol 2009; 104(9): 1292-5.
    • (2009) Am J Cardiol , vol.104 , Issue.9 , pp. 1292-1295
    • Park, S.H.1    Kim, W.2    Park, C.S.3    Kang, W.Y.4    Hwang, S.H.5    Kim, W.6
  • 264
    • 77649207350 scopus 로고    scopus 로고
    • Impact of chronic kidney disease on platelet function profiles in diabetes mellitus patients with coronary artery disease taking dual antiplatelet therapy
    • Angiolillo DJ, Bernardo E, Capodanno D, et al. Impact of chronic kidney disease on platelet function profiles in diabetes mellitus patients with coronary artery disease taking dual antiplatelet therapy. J Am Coll Cardiol 2010; 55(11): 1139-46.
    • (2010) J Am Coll Cardiol , vol.55 , Issue.11 , pp. 1139-1146
    • Angiolillo, D.J.1    Bernardo, E.2    Capodanno, D.3
  • 265
    • 78149357797 scopus 로고    scopus 로고
    • Lack of effect of chronic kidney disease on clopidogrel response with high loading and maintenance doses of clopidogrel after Acute Coronary Syndrome
    • Cuisset T, Frere C, Moro PJ, et al. Lack of effect of chronic kidney disease on clopidogrel response with high loading and maintenance doses of clopidogrel after Acute Coronary Syndrome. Thromb Res 2010; 126(5): e400-e402.
    • (2010) Thromb Res , vol.126 , Issue.5
    • Cuisset, T.1    Frere, C.2    Moro, P.J.3
  • 266
    • 84858330788 scopus 로고    scopus 로고
    • Effects of Antiplatelet Therapy on Mortality and Cardiovascular and Bleeding Outcomes in Persons With Chronic Kidney Disease: A Systematic Review and Meta-analysis
    • Palmer SC, Di ML, Razavian M, et al. Effects of Antiplatelet Therapy on Mortality and Cardiovascular and Bleeding Outcomes in Persons With Chronic Kidney Disease: A Systematic Review and Meta-analysis. Ann Intern Med 2012; 156(6): 445-59.
    • (2012) Ann Intern Med , vol.156 , Issue.6 , pp. 445-459
    • Palmer, S.C.1    Di, M.L.2    Razavian, M.3
  • 267
    • 0033552883 scopus 로고    scopus 로고
    • Atherosclerosis--an inflammatory disease
    • Ross R. Atherosclerosis--an inflammatory disease. N Engl J Med 1999; 340(2): 115-26.
    • (1999) N Engl J Med , vol.340 , Issue.2 , pp. 115-126
    • Ross, R.1
  • 268
    • 33845709506 scopus 로고    scopus 로고
    • Multiple biomarkers for the prediction of first major cardiovascular events and death
    • Wang TJ, Gona P, Larson MG, et al. Multiple biomarkers for the prediction of first major cardiovascular events and death. N Engl J Med 2006; 355(25): 2631-9.
    • (2006) N Engl J Med , vol.355 , Issue.25 , pp. 2631-2639
    • Wang, T.J.1    Gona, P.2    Larson, M.G.3
  • 269
    • 33748052351 scopus 로고    scopus 로고
    • Relation between atherosclerosis risk factors and aspirin resistance in a primary prevention population
    • Faraday N, Becker DM, Yanek LR, et al. Relation between atherosclerosis risk factors and aspirin resistance in a primary prevention population. Am J Cardiol 2006; 98(6): 774-9.
    • (2006) Am J Cardiol , vol.98 , Issue.6 , pp. 774-779
    • Faraday, N.1    Becker, D.M.2    Yanek, L.R.3
  • 270
    • 67649742549 scopus 로고    scopus 로고
    • Leukocyte count is associated with increased platelet reactivity and diminished response to aspirin in healthy individuals with a family history of coronary artery disease
    • Faraday N, Yanek LR, Vaidya D, et al. Leukocyte count is associated with increased platelet reactivity and diminished response to aspirin in healthy individuals with a family history of coronary artery disease. Thromb Res 2009; 124(3): 311-7.
    • (2009) Thromb Res , vol.124 , Issue.3 , pp. 311-317
    • Faraday, N.1    Yanek, L.R.2    Vaidya, D.3
  • 271
    • 84655167209 scopus 로고    scopus 로고
    • Platelet aggregation is dependent on platelet count in patients with coronary artery disease
    • Wurtz M, Hvas AM, Kristensen SD, Grove EL. Platelet aggregation is dependent on platelet count in patients with coronary artery disease. Thromb Res 2012; 129(1): 56-61.
    • (2012) Thromb Res , vol.129 , Issue.1 , pp. 56-61
    • Wurtz, M.1    Hvas, A.M.2    Kristensen, S.D.3    Grove, E.L.4
  • 272
    • 78649732206 scopus 로고    scopus 로고
    • Association between inflammatory biomarkers and platelet aggregation in patients under chronic clopidogrel treatment
    • Bernlochner I, Steinhubl S, Braun S, et al. Association between inflammatory biomarkers and platelet aggregation in patients under chronic clopidogrel treatment. Thromb Haemost 2010; 104(6).
    • (2010) Thromb Haemost , vol.104 , Issue.6
    • Bernlochner, I.1    Steinhubl, S.2    Braun, S.3
  • 273
    • 51449118219 scopus 로고    scopus 로고
    • Elevated plasma fibrinogen and diabetes mellitus are associated with lower inhibition of platelet reactivity with clopidogrel
    • Ang L, Palakodeti V, Khalid A, et al. Elevated plasma fibrinogen and diabetes mellitus are associated with lower inhibition of platelet reactivity with clopidogrel. J Am Coll Cardiol 2008; 52(13): 1052-9.
    • (2008) J Am Coll Cardiol , vol.52 , Issue.13 , pp. 1052-1059
    • Ang, L.1    Palakodeti, V.2    Khalid, A.3
  • 274
    • 70449442585 scopus 로고    scopus 로고
    • Enhanced post-clopidogrel platelet reactivity in diabetic patients is independently related to plasma fibrinogen level but not to glycemic control
    • Gaborit B, Frere C, Cuisset T, Alessi MC, Dutour A. Enhanced post-clopidogrel platelet reactivity in diabetic patients is independently related to plasma fibrinogen level but not to glycemic control. J Thromb Haemost 2009; 7(11): 1939-41.
    • (2009) J Thromb Haemost , vol.7 , Issue.11 , pp. 1939-1941
    • Gaborit, B.1    Frere, C.2    Cuisset, T.3    Alessi, M.C.4    Dutour, A.5
  • 275
    • 70449474088 scopus 로고    scopus 로고
    • The influence of clinical characteristics, laboratory and inflammatory markers on 'high on-treatment platelet reactivity' as measured with different platelet function tests
    • Elsenberg EH, van Werkum JW, van de Wal RM, et al. The influence of clinical characteristics, laboratory and inflammatory markers on 'high on-treatment platelet reactivity' as measured with different platelet function tests. Thromb Haemost 2009; 102(4): 719-27.
    • (2009) Thromb Haemost , vol.102 , Issue.4 , pp. 719-727
    • Elsenberg, E.H.1    van Werkum, J.W.2    van de Wal, R.M.3
  • 276
    • 82955189275 scopus 로고    scopus 로고
    • A Point-of-Care Platelet Function Assay and C-Reactive Protein for Prediction of Major Cardiovascular Events After Drug-Eluting Stent Implantation
    • Park DW, Lee SW, Yun SC, et al. A Point-of-Care Platelet Function Assay and C-Reactive Protein for Prediction of Major Cardiovascular Events After Drug-Eluting Stent Implantation. J Am Coll Cardiol 2011; 58(25): 2630-9.
    • (2011) J Am Coll Cardiol , vol.58 , Issue.25 , pp. 2630-2639
    • Park, D.W.1    Lee, S.W.2    Yun, S.C.3
  • 277
    • 0030716498 scopus 로고    scopus 로고
    • Shattuck lecture--cardiovascular medicine at the turn of the millennium: Triumphs, concerns, and opportunities
    • Braunwald E. Shattuck lecture--cardiovascular medicine at the turn of the millennium: triumphs, concerns, and opportunities. N Engl J Med 1997; 337(19): 1360-9.
    • (1997) N Engl J Med , vol.337 , Issue.19 , pp. 1360-1369
    • Braunwald, E.1
  • 278
    • 0028810203 scopus 로고
    • Thromboxane biosynthesis, neutrophil and coagulative activation in type IIa hypercholesterolemia
    • Davi G, Ganci A, Averna M, et al. Thromboxane biosynthesis, neutrophil and coagulative activation in type IIa hypercholesterolemia. Thromb Haemost 1995; 74(4): 1015-9.
    • (1995) Thromb Haemost , vol.74 , Issue.4 , pp. 1015-1019
    • Davi, G.1    Ganci, A.2    Averna, M.3
  • 279
    • 0026573778 scopus 로고
    • Increased thromboxane biosynthesis in type IIa hypercholesterolemia
    • Davi G, Averna M, Catalano I, et al. Increased thromboxane biosynthesis in type IIa hypercholesterolemia. Circulation 1992; 85(5): 1792-8.
    • (1992) Circulation , vol.85 , Issue.5 , pp. 1792-1798
    • Davi, G.1    Averna, M.2    Catalano, I.3
  • 280
    • 0029833959 scopus 로고    scopus 로고
    • Inhibition of thrombin generation by aspirin is blunted in hypercholesterolemia
    • Szczeklik A, Musial J, Undas A, et al. Inhibition of thrombin generation by aspirin is blunted in hypercholesterolemia. Arterioscler Thromb Vasc Biol 1996; 16(8): 948-54.
    • (1996) Arterioscler Thromb Vasc Biol , vol.16 , Issue.8 , pp. 948-954
    • Szczeklik, A.1    Musial, J.2    Undas, A.3
  • 281
    • 0016398857 scopus 로고
    • Platelet function in hyperlipoproteinemia
    • Carvalho AC, Colman RW, Lees RS. Platelet function in hyperlipoproteinemia. N Engl J Med 1974; 290(8): 434-8.
    • (1974) N Engl J Med , vol.290 , Issue.8 , pp. 434-438
    • Carvalho, A.C.1    Colman, R.W.2    Lees, R.S.3
  • 282
    • 0037431745 scopus 로고    scopus 로고
    • Research pointers: Platelet responsiveness to aspirin in patients with hyperlipidaemia
    • Friend M, Vucenik I, Miller M. Research pointers: Platelet responsiveness to aspirin in patients with hyperlipidaemia. BMJ 2003; 326(7380): 82-3.
    • (2003) BMJ , vol.326 , Issue.7380 , pp. 82-83
    • Friend, M.1    Vucenik, I.2    Miller, M.3
  • 283
    • 47549102119 scopus 로고    scopus 로고
    • Plasma triglycerides as predictors of platelet responsiveness to aspirin in patients after first ischemic stroke
    • Karepov V, Tolpina G, Kuliczkowski W, Serebruany V. Plasma triglycerides as predictors of platelet responsiveness to aspirin in patients after first ischemic stroke. Cerebrovasc Dis 2008; 26(3): 272-6.
    • (2008) Cerebrovasc Dis , vol.26 , Issue.3 , pp. 272-276
    • Karepov, V.1    Tolpina, G.2    Kuliczkowski, W.3    Serebruany, V.4
  • 284
    • 60649084742 scopus 로고    scopus 로고
    • Effect of high dose statin therapy on platelet function; statins reduce aspirin-resistant platelet aggregation in patients with coronary heart disease
    • Tirnaksiz E, Pamukcu B, Oflaz H, Nisanci Y. Effect of high dose statin therapy on platelet function; statins reduce aspirin-resistant platelet aggregation in patients with coronary heart disease. J Thromb Thrombolysis 2009; 27(1): 24-8.
    • (2009) J Thromb Thrombolysis , vol.27 , Issue.1 , pp. 24-28
    • Tirnaksiz, E.1    Pamukcu, B.2    Oflaz, H.3    Nisanci, Y.4
  • 285
    • 54949155995 scopus 로고    scopus 로고
    • ADP-induced platelet aggregation frequently fails to detect impaired clopidogrelresponsiveness in patients with coronary artery disease compared to a P2Y12-specific assay
    • Schafer A, Weinberger S, Flierl U, et al. ADP-induced platelet aggregation frequently fails to detect impaired clopidogrelresponsiveness in patients with coronary artery disease compared to a P2Y12-specific assay. Thromb Haemost 2008; 100(4): 618-25.
    • (2008) Thromb Haemost , vol.100 , Issue.4 , pp. 618-625
    • Schafer, A.1    Weinberger, S.2    Flierl, U.3
  • 286
    • 79960101367 scopus 로고    scopus 로고
    • Early determination of clopidogrel responsiveness by platelet reactivity indexidentifies patients at risk for cardiovascular events after myocardial infarction
    • Schafer A, Flierl U, Kossler J, et al. Early determination of clopidogrel responsiveness by platelet reactivity indexidentifies patients at risk for cardiovascular events after myocardial infarction. Thromb Haemost 2011; 106(1): 141-8.
    • (2011) Thromb Haemost , vol.106 , Issue.1 , pp. 141-148
    • Schafer, A.1    Flierl, U.2    Kossler, J.3
  • 287
    • 78549231969 scopus 로고    scopus 로고
    • Antiplatelet drug resistance in the prediction of thromboembolic complications after neurointervention
    • Ryu DS, Hong CK, Sim YS, Kim CH, Jung JY, Joo JY. Antiplatelet drug resistance in the prediction of thromboembolic complications after neurointervention. J Korean Neurosurg Soc 2010; 48(4): 319-24.
    • (2010) J Korean Neurosurg Soc , vol.48 , Issue.4 , pp. 319-324
    • Ryu, D.S.1    Hong, C.K.2    Sim, Y.S.3    Kim, C.H.4    Jung, J.Y.5    Joo, J.Y.6
  • 288
    • 79961180319 scopus 로고    scopus 로고
    • Significance of clopidogrel resistance related to the stent-assisted angioplasty in patients with atherosclerotic cerebrovascular disease
    • Rho GJ, Shin WR, Kong TS, Kim MS, Lee CJ, Lee BH. Significance of clopidogrel resistance related to the stent-assisted angioplasty in patients with atherosclerotic cerebrovascular disease. J Korean Neurosurg Soc 2011; 50(1): 40-4.
    • (2011) J Korean Neurosurg Soc , vol.50 , Issue.1 , pp. 40-44
    • Rho, G.J.1    Shin, W.R.2    Kong, T.S.3    Kim, M.S.4    Lee, C.J.5    Lee, B.H.6
  • 290
    • 56349140778 scopus 로고    scopus 로고
    • The ELAPSE (Evaluation of Long-Term Clopidogrel Antiplatelet and Systemic Anti-Inflammatory Effects) study
    • Saw J, Madsen EH, Chan S, Maurer-Spurej E. The ELAPSE (Evaluation of Long-Term Clopidogrel Antiplatelet and Systemic Anti-Inflammatory Effects) study. J Am Coll Cardiol 2008; 52(23): 1826-33.
    • (2008) J Am Coll Cardiol , vol.52 , Issue.23 , pp. 1826-1833
    • Saw, J.1    Madsen, E.H.2    Chan, S.3    Maurer-Spurej, E.4
  • 291
    • 79961185454 scopus 로고    scopus 로고
    • Aspirin extrusion from human platelets through multidrug resistance protein-4-mediated transport evidence of a reduced drug action in patients after coronary artery bypass grafting
    • Mattiello T, Guerriero R, Lotti LV, et al. Aspirin extrusion from human platelets through multidrug resistance protein-4-mediated transport evidence of a reduced drug action in patients after coronary artery bypass grafting. J Am Coll Cardiol 2011; 58(7): 752-61.
    • (2011) J Am Coll Cardiol , vol.58 , Issue.7 , pp. 752-761
    • Mattiello, T.1    Guerriero, R.2    Lotti, L.V.3
  • 292
    • 33744997382 scopus 로고    scopus 로고
    • Platelet expression profiling and clinical validation of myeloid-related protein-14 as a novel determinant of cardiovascular events
    • Healy AM, Pickard MD, Pradhan AD, et al. Platelet expression profiling and clinical validation of myeloid-related protein-14 as a novel determinant of cardiovascular events. Circulation 2006; 113(19): 2278-84.
    • (2006) Circulation , vol.113 , Issue.19 , pp. 2278-2284
    • Healy, A.M.1    Pickard, M.D.2    Pradhan, A.D.3
  • 293
    • 34548316925 scopus 로고    scopus 로고
    • Myeloid-related protein 8/14 complex is released by monocytes and granulocytes at the site of coronary occlusion: A novel, early, and sensitive marker of acute coronary syndromes
    • Altwegg LA, Neidhart M, Hersberger M, et al. Myeloid-related protein 8/14 complex is released by monocytes and granulocytes at the site of coronary occlusion: a novel, early, and sensitive marker of acute coronary syndromes. Eur Heart J 2007; 28(8): 941-8.
    • (2007) Eur Heart J , vol.28 , Issue.8 , pp. 941-948
    • Altwegg, L.A.1    Neidhart, M.2    Hersberger, M.3
  • 294
    • 34547760330 scopus 로고    scopus 로고
    • A comparison of six major platelet function tests to determine the prevalence of aspirin resistance in patients with stable coronary artery disease
    • Lordkipanidze M, Pharand C, Schampaert E, Turgeon J, Palisaitis DA, Diodati JG. A comparison of six major platelet function tests to determine the prevalence of aspirin resistance in patients with stable coronary artery disease. Eur Heart J 2007; 28(14): 1702-8.
    • (2007) Eur Heart J , vol.28 , Issue.14 , pp. 1702-1708
    • Lordkipanidze, M.1    Pharand, C.2    Schampaert, E.3    Turgeon, J.4    Palisaitis, D.A.5    Diodati, J.G.6
  • 295
    • 77953160638 scopus 로고    scopus 로고
    • A comparison of platelet function tests and thromboxane metabolites to evaluate aspirin response in healthy individuals and patients with coronary artery disease
    • Grove EL, Hvas AM, Johnsen HL, et al. A comparison of platelet function tests and thromboxane metabolites to evaluate aspirin response in healthy individuals and patients with coronary artery disease. Thromb Haemost 2010; 103(6): 1245-53.
    • (2010) Thromb Haemost , vol.103 , Issue.6 , pp. 1245-1253
    • Grove, E.L.1    Hvas, A.M.2    Johnsen, H.L.3
  • 296
    • 27644465874 scopus 로고    scopus 로고
    • Clopidogrel effect on platelet reactivity in patients with stent thrombosis: Results of the CREST Study
    • Gurbel PA, Bliden KP, Samara W, et al. Clopidogrel effect on platelet reactivity in patients with stent thrombosis: results of the CREST Study. J Am Coll Cardiol 2005; 46(10): 1827-32.
    • (2005) J Am Coll Cardiol , vol.46 , Issue.10 , pp. 1827-1832
    • Gurbel, P.A.1    Bliden, K.P.2    Samara, W.3
  • 297
    • 34447636769 scopus 로고    scopus 로고
    • Vasodilatorstimulated phosphoprotein phosphorylation analysis prior to percutaneous coronary intervention for exclusion of postprocedural major adverse cardiovascular events
    • Bonello L, Paganelli F, Arpin-Bornet M, et al. Vasodilatorstimulated phosphoprotein phosphorylation analysis prior to percutaneous coronary intervention for exclusion of postprocedural major adverse cardiovascular events. J Thromb Haemost 2007; 5(8): 1630-6.
    • (2007) J Thromb Haemost , vol.5 , Issue.8 , pp. 1630-1636
    • Bonello, L.1    Paganelli, F.2    Arpin-Bornet, M.3
  • 298
    • 44949173754 scopus 로고    scopus 로고
    • Prognostic significance of post-clopidogrel platelet reactivity assessed by a point-ofcare assay on thrombotic events after drug-eluting stent implantation
    • Price MJ, Endemann S, Gollapudi RR, et al. Prognostic significance of post-clopidogrel platelet reactivity assessed by a point-ofcare assay on thrombotic events after drug-eluting stent implantation. Eur Heart J 2008; 29(8): 992-1000.
    • (2008) Eur Heart J , vol.29 , Issue.8 , pp. 992-1000
    • Price, M.J.1    Endemann, S.2    Gollapudi, R.R.3
  • 299
    • 74749097435 scopus 로고    scopus 로고
    • Antiplatelet effects of clopidogrel and bleeding in patients undergoing coronary stent placement
    • Sibbing D, Schulz S, Braun S, et al. Antiplatelet effects of clopidogrel and bleeding in patients undergoing coronary stent placement. J Thromb Haemost 2010; 8(2): 250-6.
    • (2010) J Thromb Haemost , vol.8 , Issue.2 , pp. 250-256
    • Sibbing, D.1    Schulz, S.2    Braun, S.3
  • 300
    • 9644281093 scopus 로고    scopus 로고
    • The difference between clopidogrel responsiveness and posttreatment platelet reactivity
    • Samara WM, Bliden KP, Tantry US, Gurbel PA. The difference between clopidogrel responsiveness and posttreatment platelet reactivity. Thromb Res 2005; 115(1-2): 89-94.
    • (2005) Thromb Res , vol.115 , Issue.1-2 , pp. 89-94
    • Samara, W.M.1    Bliden, K.P.2    Tantry, U.S.3    Gurbel, P.A.4
  • 301
    • 77955603691 scopus 로고    scopus 로고
    • Platelet aggregation and its association with stent thrombosis and bleeding in clopidogrel-treated patients: Initial evidence of a therapeutic window
    • Sibbing D, Steinhubl SR, Schulz S, Schomig A, Kastrati A. Platelet aggregation and its association with stent thrombosis and bleeding in clopidogrel-treated patients: initial evidence of a therapeutic window. J Am Coll Cardiol 2010; 56(4): 317-8.
    • (2010) J Am Coll Cardiol , vol.56 , Issue.4 , pp. 317-318
    • Sibbing, D.1    Steinhubl, S.R.2    Schulz, S.3    Schomig, A.4    Kastrati, A.5
  • 302
    • 77953911457 scopus 로고    scopus 로고
    • Consensus and future directions on the definition of high on-treatment platelet reactivity to adenosine diphosphate
    • Bonello L, Tantry US, Marcucci R, et al. Consensus and future directions on the definition of high on-treatment platelet reactivity to adenosine diphosphate. J Am Coll Cardiol 2010; 56(12): 919-33.
    • (2010) J Am Coll Cardiol , vol.56 , Issue.12 , pp. 919-933
    • Bonello, L.1    Tantry, U.S.2    Marcucci, R.3
  • 303
    • 33645861080 scopus 로고    scopus 로고
    • Clopidogrel and aspirin versus aspirin alone for the prevention of atherothrombotic events
    • Bhatt DL, Fox KA, Hacke W, et al. Clopidogrel and aspirin versus aspirin alone for the prevention of atherothrombotic events. N Engl J Med 2006; 354(16): 1706-17.
    • (2006) N Engl J Med , vol.354 , Issue.16 , pp. 1706-1717
    • Bhatt, D.L.1    Fox, K.A.2    Hacke, W.3
  • 304
    • 58149476444 scopus 로고    scopus 로고
    • Tailored clopidogrel loading dose according to platelet reactivity monitoring to prevent acute and subacute stent thrombosis
    • Bonello L, Camoin-Jau L, Armero S, et al. Tailored clopidogrel loading dose according to platelet reactivity monitoring to prevent acute and subacute stent thrombosis. Am J Cardiol 2009; 103(1): 5-10.
    • (2009) Am J Cardiol , vol.103 , Issue.1 , pp. 5-10
    • Bonello, L.1    Camoin-Jau, L.2    Armero, S.3
  • 305
    • 79960603731 scopus 로고    scopus 로고
    • High on-treatment platelet reactivity after prasugrel loading dose and cardiovascular events after percutaneous coronary intervention in acute coronary syndromes
    • Bonello L, Pansieri M, Mancini J, et al. High on-treatment platelet reactivity after prasugrel loading dose and cardiovascular events after percutaneous coronary intervention in acute coronary syndromes. J Am Coll Cardiol 2011; 58(5): 467-73.
    • (2011) J Am Coll Cardiol , vol.58 , Issue.5 , pp. 467-473
    • Bonello, L.1    Pansieri, M.2    Mancini, J.3
  • 306
    • 24944474901 scopus 로고    scopus 로고
    • Aspirin resistance: Position paper of the Working Group on Aspirin Resistance
    • Michelson AD, Cattaneo M, Eikelboom JW, et al. Aspirin resistance: position paper of the Working Group on Aspirin Resistance. J Thromb Haemost 2005; 3(6): 1309-11.
    • (2005) J Thromb Haemost , vol.3 , Issue.6 , pp. 1309-1311
    • Michelson, A.D.1    Cattaneo, M.2    Eikelboom, J.W.3


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