메뉴 건너뛰기




Volumn 268, Issue 6, 2010, Pages 516-529

Antiplatelet drug interactions

Author keywords

Antiplatelet therapy; Drug interaction; Drugs

Indexed keywords

ACETYLSALICYLIC ACID; ANTICOAGULANT AGENT; ANTITHROMBOCYTIC AGENT; CALCIUM CHANNEL BLOCKING AGENT; CELECOXIB; CLOPIDOGREL; CYCLOOXYGENASE 1; CYCLOOXYGENASE 2; CYCLOOXYGENASE 2 INHIBITOR; CYTOCHROME P450 2C19; CYTOCHROME P450 3A4; CYTOCHROME P450 3A5; DICLOFENAC; FAMOTIDINE; FLURBIPROFEN; HISTAMINE H2 RECEPTOR ANTAGONIST; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; IBUPROFEN; INDOMETACIN; LUMIRACOXIB; NAPROXEN; NONSTEROID ANTIINFLAMMATORY AGENT; OMEPRAZOLE; PLACEBO; PRASUGREL; PROTON PUMP INHIBITOR; ROFECOXIB; SEROTONIN UPTAKE INHIBITOR; TIAPROFENIC ACID; UNINDEXED DRUG;

EID: 78649467948     PISSN: 09546820     EISSN: 13652796     Source Type: Journal    
DOI: 10.1111/j.1365-2796.2010.02299.x     Document Type: Review
Times cited : (47)

References (141)
  • 1
    • 65849268320 scopus 로고    scopus 로고
    • Aspirin in the primary and secondary prevention of vascular disease: collaborative meta-analysis of individual participant data from randomised trials
    • Antithrombotic Trialists' (ATT) Collaboration.
    • Antithrombotic Trialists' (ATT) Collaboration. Aspirin in the primary and secondary prevention of vascular disease: collaborative meta-analysis of individual participant data from randomised trials. Lancet 2009; 373: 1849-60.
    • (2009) Lancet , vol.373 , pp. 1849-1860
  • 2
    • 0037190695 scopus 로고    scopus 로고
    • Evaluation of the benefits and risks of low-dose aspirin in the secondary prevention of cardiovascular and cerebrovascular events
    • Weisman SM, Graham DY. Evaluation of the benefits and risks of low-dose aspirin in the secondary prevention of cardiovascular and cerebrovascular events. Arch Intern Med 2002; 162: 2197-202.
    • (2002) Arch Intern Med , vol.162 , pp. 2197-2202
    • Weisman, S.M.1    Graham, D.Y.2
  • 3
    • 0034763373 scopus 로고    scopus 로고
    • Aspirin for primary prevention of coronary heart disease: safety and absolute benefit related to coronary risk derived from meta-analysis of randomised trials
    • Sanmuganathan PS, Ghahramani P, Jackson PR, Wallis EJ, Ramsay LE. Aspirin for primary prevention of coronary heart disease: safety and absolute benefit related to coronary risk derived from meta-analysis of randomised trials. Heart 2001; 85: 265-71.
    • (2001) Heart , vol.85 , pp. 265-271
    • Sanmuganathan, P.S.1    Ghahramani, P.2    Jackson, P.R.3    Wallis, E.J.4    Ramsay, L.E.5
  • 4
    • 0037080065 scopus 로고    scopus 로고
    • Aspirin for the primary prevention of cardiovascular events: a summary of the evidence for the U.S. Preventive Services Task Force
    • Hayden M, Pignone M, Phillips C, Mulrow C. Aspirin for the primary prevention of cardiovascular events: a summary of the evidence for the U.S. Preventive Services Task Force. Ann Intern Med 2002; 136: 161-72.
    • (2002) Ann Intern Med , vol.136 , pp. 161-172
    • Hayden, M.1    Pignone, M.2    Phillips, C.3    Mulrow, C.4
  • 5
    • 0037046655 scopus 로고    scopus 로고
    • Clinical practice. Aspirin for primary prevention of coronary events
    • Lauer M. Clinical practice. Aspirin for primary prevention of coronary events. N Engl J Med 2002; 346: 1468-74.
    • (2002) N Engl J Med , vol.346 , pp. 1468-1474
    • Lauer, M.1
  • 6
    • 62549131608 scopus 로고    scopus 로고
    • Aspirin for the primary prevention of cardiovascular events: an update of the evidence for the U.S. Preventive Services Task Force
    • Wolff T, Miller T, Ko S. Aspirin for the primary prevention of cardiovascular events: an update of the evidence for the U.S. Preventive Services Task Force. Ann Intern Med 2009; 150: 405-10.
    • (2009) Ann Intern Med , vol.150 , pp. 405-410
    • Wolff, T.1    Miller, T.2    Ko, S.3
  • 7
    • 85007671077 scopus 로고    scopus 로고
    • Antiplatelet therapy and atherosclerotic events. Risks and patients' values need to be included in decision about aspirin for prevention of coronary heart disease
    • Pignone M, Mulrow C. Antiplatelet therapy and atherosclerotic events. Risks and patients' values need to be included in decision about aspirin for prevention of coronary heart disease. BMJ 2002; 324: 917-8.
    • (2002) BMJ , vol.324 , pp. 917-918
    • Pignone, M.1    Mulrow, C.2
  • 8
    • 65549105821 scopus 로고    scopus 로고
    • Aspirin for the prevention of cardiovascular events in patients with peripheral artery disease: a meta-analysis of randomized trials
    • Berger JS, Krantz MJ, Kittelson JM, Hiatt WR. Aspirin for the prevention of cardiovascular events in patients with peripheral artery disease: a meta-analysis of randomized trials. JAMA 2009; 301: 1909-19.
    • (2009) JAMA , vol.301 , pp. 1909-1919
    • Berger, J.S.1    Krantz, M.J.2    Kittelson, J.M.3    Hiatt, W.R.4
  • 9
    • 77649198148 scopus 로고    scopus 로고
    • Aspirin for Asymptomatic Atherosclerosis Trialists. Aspirin for prevention of cardiovascular events in a general population screened for a low ankle brachial index: a randomized controlled trial
    • Fowkes FG, Price JF, Stewart MC et al. Aspirin for Asymptomatic Atherosclerosis Trialists. Aspirin for prevention of cardiovascular events in a general population screened for a low ankle brachial index: a randomized controlled trial. JAMA 2010; 303: 841-8.
    • (2010) JAMA , vol.303 , pp. 841-848
    • Fowkes, F.G.1    Price, J.F.2    Stewart, M.C.3
  • 10
    • 54949131747 scopus 로고    scopus 로고
    • The prevention of progression of arterial disease and diabetes (POPADAD) trial: factorial randomised placebo controlled trial of aspirin and antioxidants in patients with diabetes and asymptomatic peripheral arterial disease
    • Belch J, MacCuish A, Campbell I et al. The prevention of progression of arterial disease and diabetes (POPADAD) trial: factorial randomised placebo controlled trial of aspirin and antioxidants in patients with diabetes and asymptomatic peripheral arterial disease. BMJ 2008; 337: a1840.
    • (2008) BMJ , vol.337
    • Belch, J.1    MacCuish, A.2    Campbell, I.3
  • 11
    • 56149113603 scopus 로고    scopus 로고
    • Japanese Primary Prevention of Atherosclerosis With Aspirin for Diabetes (JPAD) Trial Investigators. Low-dose aspirin for primary prevention of atherosclerotic events in patients with type 2 diabetes: a randomized controlled trial
    • Ogawa H, Nakayama M, Morimoto T et al. Japanese Primary Prevention of Atherosclerosis With Aspirin for Diabetes (JPAD) Trial Investigators. Low-dose aspirin for primary prevention of atherosclerotic events in patients with type 2 diabetes: a randomized controlled trial. JAMA 2008; 300: 2134-41.
    • (2008) JAMA , vol.300 , pp. 2134-2141
    • Ogawa, H.1    Nakayama, M.2    Morimoto, T.3
  • 12
    • 15744378579 scopus 로고    scopus 로고
    • A randomized trial of low-dose aspirin in the primary prevention of cardiovascular disease in women
    • Ridker PM, Cook NR, Lee IM et al. A randomized trial of low-dose aspirin in the primary prevention of cardiovascular disease in women. N Engl J Med 2005; 352: 1293-304.
    • (2005) N Engl J Med , vol.352 , pp. 1293-1304
    • Ridker, P.M.1    Cook, N.R.2    Lee, I.M.3
  • 13
    • 0037065502 scopus 로고    scopus 로고
    • Collaborative meta-analysis of randomised trials of antiplatelet therapy for prevention of death, myocardial infarction, and stroke in high risk patients
    • Anti-thrombotic Trialists' Collaboration.
    • Anti-thrombotic Trialists' Collaboration. Collaborative meta-analysis of randomised trials of antiplatelet therapy for prevention of death, myocardial infarction, and stroke in high risk patients. BMJ 2002; 324: 71-86.
    • (2002) BMJ , vol.324 , pp. 71-86
  • 14
    • 71749105108 scopus 로고    scopus 로고
    • Aspirin for primary prevention of cardiovascular events in people with diabetes: meta-analysis of randomised controlled trials
    • De Berardis G, Sacco M, Strippoli GF et al. Aspirin for primary prevention of cardiovascular events in people with diabetes: meta-analysis of randomised controlled trials. BMJ 2009; 339: b453.
    • (2009) BMJ , vol.339
    • De Berardis, G.1    Sacco, M.2    Strippoli, G.F.3
  • 15
    • 77951605056 scopus 로고    scopus 로고
    • Don't use aspirin for primary prevention of cardiovascular disease
    • Barnett H, Burrill P, Iheanacho I. Don't use aspirin for primary prevention of cardiovascular disease. BMJ 2010; 340: c1805.
    • (2010) BMJ , vol.340
    • Barnett, H.1    Burrill, P.2    Iheanacho, I.3
  • 16
    • 85052587841 scopus 로고    scopus 로고
    • The mechanism of action of aspirin
    • Vane JR, Botting RM. The mechanism of action of aspirin. Thromb Res 2003; 15: 110.
    • (2003) Thromb Res , vol.15 , pp. 110
    • Vane, J.R.1    Botting, R.M.2
  • 18
    • 0037046196 scopus 로고    scopus 로고
    • Aspirin-resistant thromboxane biosynthesis and the risk of myocardial infarction, stroke, or cardiovascular death in patients at high risk for cardiovascular events
    • Eikelboom JW, Hirsh J, Weitz JI, Johnston M, Yi Q, Yusuf S. Aspirin-resistant thromboxane biosynthesis and the risk of myocardial infarction, stroke, or cardiovascular death in patients at high risk for cardiovascular events. Circulation 2002; 105: 1650-5.
    • (2002) Circulation , vol.105 , pp. 1650-1655
    • Eikelboom, J.W.1    Hirsh, J.2    Weitz, J.I.3    Johnston, M.4    Yi, Q.5    Yusuf, S.6
  • 19
    • 0037046174 scopus 로고    scopus 로고
    • Why are some individuals resistant to the cardioprotective effects of aspirin?: Could it be thromboxane A2?
    • Halushka MK, Halushka PV. Why are some individuals resistant to the cardioprotective effects of aspirin?: Could it be thromboxane A2? Circulation 2002; 105: 1620-2.
    • (2002) Circulation , vol.105 , pp. 1620-1622
    • Halushka, M.K.1    Halushka, P.V.2
  • 20
    • 0037454168 scopus 로고    scopus 로고
    • A prospective, blinded determination of the natural history of aspirin resistance among stable patients with cardiovascular disease
    • Erratum in: J Am Coll Cardiol 2006;48:1918.
    • Gum PA, Kottke-Marchant K, Welsh PA, White J, Topol EJ. A prospective, blinded determination of the natural history of aspirin resistance among stable patients with cardiovascular disease. J Am Coll Cardiol 2003; 41: 961-5. Erratum in: J Am Coll Cardiol 2006;48:1918.
    • (2003) J Am Coll Cardiol , vol.41 , pp. 961-965
    • Gum, P.A.1    Kottke-Marchant, K.2    Welsh, P.A.3    White, J.4    Topol, E.J.5
  • 21
    • 38949119325 scopus 로고    scopus 로고
    • Aspirin "resistance" and risk of cardiovascular morbidity: systematic review and meta-analysis
    • Krasopoulos G, Brister SJ, Beattie WS, Buchanan MR. Aspirin "resistance" and risk of cardiovascular morbidity: systematic review and meta-analysis. BMJ 2008; 336: 195-8.
    • (2008) BMJ , vol.336 , pp. 195-198
    • Krasopoulos, G.1    Brister, S.J.2    Beattie, W.S.3    Buchanan, M.R.4
  • 22
    • 34250816849 scopus 로고    scopus 로고
    • Aspirin resistance and adverse clinical events in patients with coronary artery disease
    • Chen WH, Cheng X, Lee PY et al. Aspirin resistance and adverse clinical events in patients with coronary artery disease. Am J Med 2007; 120: 631-5.
    • (2007) Am J Med , vol.120 , pp. 631-635
    • Chen, W.H.1    Cheng, X.2    Lee, P.Y.3
  • 23
    • 0032562005 scopus 로고    scopus 로고
    • Thrombosis prevention trial: randomised trial of low-intensity oral anticoagulation with warfarin and low-dose aspirin in the primary prevention of ischaemic heart disease in men at increased risk. The Medical Research Council's General Practice Research Framework
    • Thrombosis prevention trial: randomised trial of low-intensity oral anticoagulation with warfarin and low-dose aspirin in the primary prevention of ischaemic heart disease in men at increased risk. The Medical Research Council's General Practice Research Framework. Lancet 1998; 35: 233-41.
    • (1998) Lancet , vol.35 , pp. 233-241
  • 24
    • 2942739117 scopus 로고    scopus 로고
    • Should hypertensive patients take aspirin? A report from the Food and Drug Administration
    • Pickering TG. Should hypertensive patients take aspirin? A report from the Food and Drug Administration. J Clin Hypertens 2004; 6: 146-9.
    • (2004) J Clin Hypertens , vol.6 , pp. 146-149
    • Pickering, T.G.1
  • 25
    • 78649467775 scopus 로고    scopus 로고
    • [accessed on 26 October 2010].
    • & [accessed on 26 October 2010].
  • 26
    • 18144373789 scopus 로고    scopus 로고
    • Analysis of risk of bleeding complications after different doses of aspirin in 192,036 patients enrolled in 31 randomized controlled trials
    • Serebruany VL, Steinhubl SR, Berger PB et al. Analysis of risk of bleeding complications after different doses of aspirin in 192, 036 patients enrolled in 31 randomized controlled trials. Am J Cardiol 2005; 95: 1218-22.
    • (2005) Am J Cardiol , vol.95 , pp. 1218-1222
    • Serebruany, V.L.1    Steinhubl, S.R.2    Berger, P.B.3
  • 27
    • 0036140865 scopus 로고    scopus 로고
    • Incidence of serious upper gastrointestinal bleeding/perforation in the general population: review of epidemiologic studies
    • Hernández-Díaz S, García Rodríguez LA. Incidence of serious upper gastrointestinal bleeding/perforation in the general population: review of epidemiologic studies. J Clin Epidemiol 2002; 55: 157-63.
    • (2002) J Clin Epidemiol , vol.55 , pp. 157-163
    • Hernández-Díaz, S.1    García Rodríguez, L.A.2
  • 28
    • 3042723720 scopus 로고    scopus 로고
    • Adverse drug reactions as cause of admission to hospital: prospective analysis of 18 820 patients
    • Pirmohamed M, James S, Meakin S et al. Adverse drug reactions as cause of admission to hospital: prospective analysis of 18 820 patients. BMJ 2004; 329: 15-9.
    • (2004) BMJ , vol.329 , pp. 15-19
    • Pirmohamed, M.1    James, S.2    Meakin, S.3
  • 29
    • 20444453976 scopus 로고    scopus 로고
    • Epidemiological modelling of routine use of low dose aspirin for the primary prevention of coronary heart disease and stroke in those aged > or =70
    • Nelson MR, Liew D, Bertram M, Vos T. Epidemiological modelling of routine use of low dose aspirin for the primary prevention of coronary heart disease and stroke in those aged > or =70. BMJ 2005; 330: 1306.
    • (2005) BMJ , vol.330 , pp. 1306
    • Nelson, M.R.1    Liew, D.2    Bertram, M.3    Vos, T.4
  • 30
    • 25844437487 scopus 로고    scopus 로고
    • The lady aspirin for cardiovascular disease
    • Verheugt FW, Smith Jr SC. The lady aspirin for cardiovascular disease. Lancet 2005; 366: 1148-50.
    • (2005) Lancet , vol.366 , pp. 1148-1150
    • Verheugt, F.W.1    Smith Jr, S.C.2
  • 31
    • 1242306686 scopus 로고    scopus 로고
    • Cardiovascular prophylaxis with aspirin: costs of supply and management of upper gastrointestinal and renal toxicity
    • Morant SV, McMahon AD, Cleland JG, Davey PG, MacDonald TM. Cardiovascular prophylaxis with aspirin: costs of supply and management of upper gastrointestinal and renal toxicity. Br J Clin Pharmacol 2004; 57: 188-98.
    • (2004) Br J Clin Pharmacol , vol.57 , pp. 188-198
    • Morant, S.V.1    McMahon, A.D.2    Cleland, J.G.3    Davey, P.G.4    MacDonald, T.M.5
  • 32
    • 0037065519 scopus 로고    scopus 로고
    • Non-steroidal anti-inflammatory drugs and risk of coronary heart disease: an observational cohort study
    • Ray WA, Stein CM, Daughe JR, Hall K, Arbogast PG, Griffin MR. Non-steroidal anti-inflammatory drugs and risk of coronary heart disease: an observational cohort study. Lancet 2002; 359: 118-23.
    • (2002) Lancet , vol.359 , pp. 118-123
    • Ray, W.A.1    Stein, C.M.2    Daughe, J.R.3    Hall, K.4    Arbogast, P.G.5    Griffin, M.R.6
  • 33
    • 18344368896 scopus 로고    scopus 로고
    • Risk of hospitalization for myocardial infarction among users of rofecoxib, celecoxib, and other NSAIDs: a population-based case-control study
    • Johnsen SP, Larsson H, Tarone RE et al. Risk of hospitalization for myocardial infarction among users of rofecoxib, celecoxib, and other NSAIDs: a population-based case-control study. Arch Intern Med 2005; 165: 978-84.
    • (2005) Arch Intern Med , vol.165 , pp. 978-984
    • Johnsen, S.P.1    Larsson, H.2    Tarone, R.E.3
  • 34
    • 0037182013 scopus 로고    scopus 로고
    • Nonsteroidal anti-inflammatory drug use and acute myocardial infarction
    • Solomon DH, Glynn RJ, Levin R, Avorn J. Nonsteroidal anti-inflammatory drug use and acute myocardial infarction. Arch Intern Med 2002; 162: 1099-104.
    • (2002) Arch Intern Med , vol.162 , pp. 1099-1104
    • Solomon, D.H.1    Glynn, R.J.2    Levin, R.3    Avorn, J.4
  • 35
    • 0037182023 scopus 로고    scopus 로고
    • Association between naproxen use and protection against acute myocardial infarction
    • Rahme E, Pilote L, LeLorier J. Association between naproxen use and protection against acute myocardial infarction. Arch Intern Med 2002; 162: 1111-5.
    • (2002) Arch Intern Med , vol.162 , pp. 1111-1115
    • Rahme, E.1    Pilote, L.2    LeLorier, J.3
  • 36
    • 3042558200 scopus 로고    scopus 로고
    • Nonsteroidal antiinflammatory drugs and the risk of myocardial infarction in the general population
    • Garcia Rodriguez LA, Varas-Lorenzo C, Maguire A, Gonzalez-Perez A. Nonsteroidal antiinflammatory drugs and the risk of myocardial infarction in the general population. Circulation 2004; 109: 3000-6.
    • (2004) Circulation , vol.109 , pp. 3000-3006
    • Garcia Rodriguez, L.A.1    Varas-Lorenzo, C.2    Maguire, A.3    Gonzalez-Perez, A.4
  • 37
    • 0033933177 scopus 로고    scopus 로고
    • Differential effects of aspirin and non-aspirin nonsteroidal anti-inflammatory drugs in the primary prevention of myocardial infarction in postmenopausal women
    • Garcia Rodriguez LA, Varas C, Patrono C. Differential effects of aspirin and non-aspirin nonsteroidal anti-inflammatory drugs in the primary prevention of myocardial infarction in postmenopausal women. Epidemiology 2000; 11: 382-7.
    • (2000) Epidemiology , vol.11 , pp. 382-387
    • Garcia Rodriguez, L.A.1    Varas, C.2    Patrono, C.3
  • 38
    • 0037463569 scopus 로고    scopus 로고
    • Effect of selective cyclooxygenase 2 inhibitors and naproxen on short-term risk of acute myocardial infarction in the elderly
    • Mamdani M, Rochon P, Juurlink DN et al. Effect of selective cyclooxygenase 2 inhibitors and naproxen on short-term risk of acute myocardial infarction in the elderly. Arch Intern Med 2003; 163: 481-6.
    • (2003) Arch Intern Med , vol.163 , pp. 481-486
    • Mamdani, M.1    Rochon, P.2    Juurlink, D.N.3
  • 39
    • 2442493150 scopus 로고    scopus 로고
    • Relationship between selective cyclooxygenase-2 inhibitors and acute myocardial infarction in older adults
    • Solomon DH, Schneeweiss S, Glynn RJ et al. Relationship between selective cyclooxygenase-2 inhibitors and acute myocardial infarction in older adults. Circulation 2004; 109: 2068-73.
    • (2004) Circulation , vol.109 , pp. 2068-2073
    • Solomon, D.H.1    Schneeweiss, S.2    Glynn, R.J.3
  • 40
    • 13444263619 scopus 로고    scopus 로고
    • Risk of acute myocardial infarction and sudden cardiac death in patients treated with cyclo-oxygenase 2 selective and non-selective non-steroidal anti-inflammatory drugs: nested case-control study
    • Graham DJ, Campen D, Hui R et al. Risk of acute myocardial infarction and sudden cardiac death in patients treated with cyclo-oxygenase 2 selective and non-selective non-steroidal anti-inflammatory drugs: nested case-control study. Lancet 2005; 365: 475-81.
    • (2005) Lancet , vol.365 , pp. 475-481
    • Graham, D.J.1    Campen, D.2    Hui, R.3
  • 41
    • 0027250074 scopus 로고
    • Evaluation of flurbiprofen for prevention of reinfarction and reocclusion after successful thrombolysis or angioplasty in acute myocardial infarction. The Flurbiprofen French Trial
    • Brochier ML. Evaluation of flurbiprofen for prevention of reinfarction and reocclusion after successful thrombolysis or angioplasty in acute myocardial infarction. The Flurbiprofen French Trial. Eur Heart J 1993; 14: 951-7.
    • (1993) Eur Heart J , vol.14 , pp. 951-957
    • Brochier, M.L.1
  • 42
    • 0031866645 scopus 로고    scopus 로고
    • Indobufen compared with aspirin and dipyridamole on graft patency after coronary artery bypass surgery: results of a combined analysis
    • Cataldo G, Heiman F, Lavezzari M, Marubini E. Indobufen compared with aspirin and dipyridamole on graft patency after coronary artery bypass surgery: results of a combined analysis. Coron Artery Dis 1998; 9: 217-22.
    • (1998) Coron Artery Dis , vol.9 , pp. 217-222
    • Cataldo, G.1    Heiman, F.2    Lavezzari, M.3    Marubini, E.4
  • 43
    • 33749339372 scopus 로고    scopus 로고
    • Cardiovascular risk and inhibition of cyclooxygenase: a systematic review of the observational studies of selective and nonselective inhibitors of cyclooxygenase 2
    • McGettigan P, Henry D. Cardiovascular risk and inhibition of cyclooxygenase: a systematic review of the observational studies of selective and nonselective inhibitors of cyclooxygenase 2. JAMA 2006; 296: 1633-44.
    • (2006) JAMA , vol.296 , pp. 1633-1644
    • McGettigan, P.1    Henry, D.2
  • 44
    • 33744976771 scopus 로고    scopus 로고
    • Do selective cyclo-oxygenase-2 inhibitors and traditional non-steroidal anti-inflammatory drugs increase the risk of atherothrombosis? Meta-analysis of randomised trials
    • Kearney PM, Baigent C, Godwin J, Halls H, Emberson JR, Patrono C. Do selective cyclo-oxygenase-2 inhibitors and traditional non-steroidal anti-inflammatory drugs increase the risk of atherothrombosis? Meta-analysis of randomised trials. BMJ 2006; 332: 1302-8.
    • (2006) BMJ , vol.332 , pp. 1302-1308
    • Kearney, P.M.1    Baigent, C.2    Godwin, J.3    Halls, H.4    Emberson, J.R.5    Patrono, C.6
  • 45
    • 77957879690 scopus 로고    scopus 로고
    • Cause-specific cardiovascular risk associated with nonsteroidal antiinflammatory drugs among healthy individuals
    • Fosbøl EL, Folke F, Jacobsen S et al. Cause-specific cardiovascular risk associated with nonsteroidal antiinflammatory drugs among healthy individuals. Circ Cardiovasc Qual Outcomes 2010; 3: 395-405.
    • (2010) Circ Cardiovasc Qual Outcomes , vol.3 , pp. 395-405
    • Fosbøl, E.L.1    Folke, F.2    Jacobsen, S.3
  • 46
    • 0037421985 scopus 로고    scopus 로고
    • A randomized trial of aspirin to prevent colorectal adenomas
    • Baron JA, Cole BF, Sandler RS et al. A randomized trial of aspirin to prevent colorectal adenomas. N Engl J Med 2003; 348: 891-9.
    • (2003) N Engl J Med , vol.348 , pp. 891-899
    • Baron, J.A.1    Cole, B.F.2    Sandler, R.S.3
  • 47
    • 33645242688 scopus 로고    scopus 로고
    • Is there an interaction between the cardiovascular protective effects of low-dose aspirin and ibuprofen?
    • MacDonald TM, Wei L. Is there an interaction between the cardiovascular protective effects of low-dose aspirin and ibuprofen? Basic Clin Pharmacol Toxicol 2006; 98: 275-80.
    • (2006) Basic Clin Pharmacol Toxicol , vol.98 , pp. 275-280
    • MacDonald, T.M.1    Wei, L.2
  • 48
    • 0035807799 scopus 로고    scopus 로고
    • A high level of cyclooxygenase-2 inhibitor selectivity is associated with a reduced interference of platelet cyclooxygenase-1 inactivation by aspirin
    • Ouellet M, Riendeau D, Percival MD. A high level of cyclooxygenase-2 inhibitor selectivity is associated with a reduced interference of platelet cyclooxygenase-1 inactivation by aspirin. Proc Natl Acad Sci USA 2001; 98: 14583-8.
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 14583-14588
    • Ouellet, M.1    Riendeau, D.2    Percival, M.D.3
  • 49
    • 0020558909 scopus 로고
    • Ibuprofen protects platelet cyclooxygenase from irreversible inhibition by aspirin
    • Rao GHR, Johnson GG, Reddy KR, White JG. Ibuprofen protects platelet cyclooxygenase from irreversible inhibition by aspirin. Arteriosclerosis 1983; 3: 383-8.
    • (1983) Arteriosclerosis , vol.3 , pp. 383-388
    • Rao, G.H.R.1    Johnson, G.G.2    Reddy, K.R.3    White, J.G.4
  • 50
    • 0020360347 scopus 로고
    • Indomethacin prevents the long-lasting inhibitory effect of aspirin on human platelet cyclo-oxygenase activity
    • Livio M, Del Maschio A, Cerletti C, De Gaetano G. Indomethacin prevents the long-lasting inhibitory effect of aspirin on human platelet cyclo-oxygenase activity. Prostaglandins 1982; 23: 787-96.
    • (1982) Prostaglandins , vol.23 , pp. 787-796
    • Livio, M.1    Del Maschio, A.2    Cerletti, C.3    De Gaetano, G.4
  • 51
    • 17144407991 scopus 로고    scopus 로고
    • Pharmacodynamic interaction of naproxen with low-dose aspirin in healthy subjects
    • Capone ML, Sciulli MG, Tacconelli S et al. Pharmacodynamic interaction of naproxen with low-dose aspirin in healthy subjects. J Am Coll Cardiol 2005; 45: 1295-301.
    • (2005) J Am Coll Cardiol , vol.45 , pp. 1295-1301
    • Capone, M.L.1    Sciulli, M.G.2    Tacconelli, S.3
  • 52
    • 41249103710 scopus 로고    scopus 로고
    • The antiplatelet effect of six non-steroidal anti-inflammatory drugs and their pharmacodynamic interaction with aspirin in healthy volunteers
    • Gladding PA, Webster MW, Farrell HB, Zeng IS, Park R, Ruijne N. The antiplatelet effect of six non-steroidal anti-inflammatory drugs and their pharmacodynamic interaction with aspirin in healthy volunteers. Am J Cardiol 2008; 101: 1060-3.
    • (2008) Am J Cardiol , vol.101 , pp. 1060-1063
    • Gladding, P.A.1    Webster, M.W.2    Farrell, H.B.3    Zeng, I.S.4    Park, R.5    Ruijne, N.6
  • 53
    • 0035924765 scopus 로고    scopus 로고
    • Cyclooxygenase inhibitors and the antiplatelet effects of aspirin
    • Catella-Lawson F, Reilly MP, Kapoor SC et al. Cyclooxygenase inhibitors and the antiplatelet effects of aspirin. N Engl J Med 2001; 345: 1809-17.
    • (2001) N Engl J Med , vol.345 , pp. 1809-1817
    • Catella-Lawson, F.1    Reilly, M.P.2    Kapoor, S.C.3
  • 55
    • 0037442182 scopus 로고    scopus 로고
    • Effect of ibuprofen on cardioprotective effect of aspirin
    • MacDonald TM, Wei L. Effect of ibuprofen on cardioprotective effect of aspirin. Lancet 2003; 361: 573-4.
    • (2003) Lancet , vol.361 , pp. 573-574
    • MacDonald, T.M.1    Wei, L.2
  • 56
    • 1542499460 scopus 로고    scopus 로고
    • The effects of nonselective non-aspirin non-steroidal anti-inflammatory medications on the risk of nonfatal myocardial infarction and their interaction with aspirin
    • Kimmel SE, Berlin JA, Reilly M et al. The effects of nonselective non-aspirin non-steroidal anti-inflammatory medications on the risk of nonfatal myocardial infarction and their interaction with aspirin. J Am Coll Cardiol 2004; 43: 985-90.
    • (2004) J Am Coll Cardiol , vol.43 , pp. 985-990
    • Kimmel, S.E.1    Berlin, J.A.2    Reilly, M.3
  • 57
    • 1542499456 scopus 로고    scopus 로고
    • The case for an adverse interaction between aspirin and non-steroidal anti-inflammatory drugs: is it time to believe the hype?
    • Curtis JP, Krumholz HM. The case for an adverse interaction between aspirin and non-steroidal anti-inflammatory drugs: is it time to believe the hype? J Am Coll Cardiol 2004; 43: 991-3.
    • (2004) J Am Coll Cardiol , vol.43 , pp. 991-993
    • Curtis, J.P.1    Krumholz, H.M.2
  • 59
    • 16344367721 scopus 로고    scopus 로고
    • Current use of nonsteroidal antiinflammatory drugs and the risk of acute myocardial infarction
    • Fischer LM, Schlienger RG, Matter CM, Jick H, Meier CR. Current use of nonsteroidal antiinflammatory drugs and the risk of acute myocardial infarction. Pharmacotherapy 2005; 25: 503-10.
    • (2005) Pharmacotherapy , vol.25 , pp. 503-510
    • Fischer, L.M.1    Schlienger, R.G.2    Matter, C.M.3    Jick, H.4    Meier, C.R.5
  • 60
    • 23444453726 scopus 로고    scopus 로고
    • Ibuprofen may abrogate the benefits of aspirin when used for secondary prevention of myocardial infarction
    • Hudson M, Baron M, Rahme E, Pilote L. Ibuprofen may abrogate the benefits of aspirin when used for secondary prevention of myocardial infarction. J Rheumatol 2005; 32: 1589-93.
    • (2005) J Rheumatol , vol.32 , pp. 1589-1593
    • Hudson, M.1    Baron, M.2    Rahme, E.3    Pilote, L.4
  • 61
    • 0344005434 scopus 로고    scopus 로고
    • Aspirin, ibuprofen, and mortality after myocardial infarction: retrospective cohort study
    • Curtis JP, Wang Y, Portnay EL, Masoudi FA, Havranek EP, Krumholz HM. Aspirin, ibuprofen, and mortality after myocardial infarction: retrospective cohort study. BMJ 2003; 327: 1322-3.
    • (2003) BMJ , vol.327 , pp. 1322-1323
    • Curtis, J.P.1    Wang, Y.2    Portnay, E.L.3    Masoudi, F.A.4    Havranek, E.P.5    Krumholz, H.M.6
  • 62
    • 0036185093 scopus 로고    scopus 로고
    • Nonsteroidal antiinflammatory drugs after acute myocardial infarction
    • Ko D, Yongfel W, Berger AK, Radford MJ, Krumholz HM. Nonsteroidal antiinflammatory drugs after acute myocardial infarction. Am Heart J 2002; 143: 475-81.
    • (2002) Am Heart J , vol.143 , pp. 475-481
    • Ko, D.1    Yongfel, W.2    Berger, A.K.3    Radford, M.J.4    Krumholz, H.M.5
  • 63
    • 0345527977 scopus 로고    scopus 로고
    • Giving aspirin and ibuprofen after myocardial infarction: clinical consequences are still unknown
    • Kimmel SE, Strom BL. Giving aspirin and ibuprofen after myocardial infarction: clinical consequences are still unknown. BMJ 2003; 327: 1298-9.
    • (2003) BMJ , vol.327 , pp. 1298-1299
    • Kimmel, S.E.1    Strom, B.L.2
  • 64
    • 0042416748 scopus 로고    scopus 로고
    • Inhibition of clinical benefits of aspirin on first myocardial infarction by nonsteroidal anti-inflammatory drugs
    • Kurth T, Glynn RJ, Walker AM et al. Inhibition of clinical benefits of aspirin on first myocardial infarction by nonsteroidal anti-inflammatory drugs. Circulation 2003; 108: 1191-5.
    • (2003) Circulation , vol.108 , pp. 1191-1195
    • Kurth, T.1    Glynn, R.J.2    Walker, A.M.3
  • 65
    • 4344578073 scopus 로고    scopus 로고
    • Comparison of lumiracoxib with naproxen and ibuprofen in the Therapeutic Arthritis Research and Gastrointestinal Event Trial (TARGET), cardiovascular outcomes: randomised controlled trial
    • Farkouh ME, Kirshner H, Harrington RA et al. Comparison of lumiracoxib with naproxen and ibuprofen in the Therapeutic Arthritis Research and Gastrointestinal Event Trial (TARGET), cardiovascular outcomes: randomised controlled trial. Lancet 2004; 364: 675-84.
    • (2004) Lancet , vol.364 , pp. 675-684
    • Farkouh, M.E.1    Kirshner, H.2    Harrington, R.A.3
  • 66
    • 0029162250 scopus 로고
    • Misoprostol reduces serious gastrointestinal complications in patients with rheumatoid arthritis receiving nonsteroidal anti-inflammatory drugs. A randomized, double-blind, placebo-controlled trial
    • Silverstein FE, Graham DY, Senior JR et al. Misoprostol reduces serious gastrointestinal complications in patients with rheumatoid arthritis receiving nonsteroidal anti-inflammatory drugs. A randomized, double-blind, placebo-controlled trial. Ann Intern Med 1995; 123: 241-9.
    • (1995) Ann Intern Med , vol.123 , pp. 241-249
    • Silverstein, F.E.1    Graham, D.Y.2    Senior, J.R.3
  • 67
    • 0034644396 scopus 로고    scopus 로고
    • Gastrointestinal toxicity with celecoxib vs nonsteroidal anti-inflammatory drugs for osteoarthritis and rheumatoid arthritis: the CLASS study: a randomized controlled trial. Celecoxib Long-term Arthritis Safety Study
    • Silverstein FE, Faich G, Goldstein JL et al. Gastrointestinal toxicity with celecoxib vs nonsteroidal anti-inflammatory drugs for osteoarthritis and rheumatoid arthritis: the CLASS study: a randomized controlled trial. Celecoxib Long-term Arthritis Safety Study. JAMA 2000; 284: 1247-55.
    • (2000) JAMA , vol.284 , pp. 1247-1255
    • Silverstein, F.E.1    Faich, G.2    Goldstein, J.L.3
  • 68
    • 85007768013 scopus 로고    scopus 로고
    • CLASS clarification: reaffirms the medical importance of the analyses and results
    • Geis GS. CLASS clarification: reaffirms the medical importance of the analyses and results. BMJ 2003; 327: 522-3.
    • (2003) BMJ , vol.327 , pp. 522-523
    • Geis, G.S.1
  • 69
    • 4344661128 scopus 로고    scopus 로고
    • Comparison of lumiracoxib with naproxen and ibuprofen in the Therapeutic Arthritis Research and Gastrointestinal Event Trial (TARGET), reduction in ulcer complications: randomised controlled trial
    • Schnitzer TJ, Burmester GR, Mysler E et al. Comparison of lumiracoxib with naproxen and ibuprofen in the Therapeutic Arthritis Research and Gastrointestinal Event Trial (TARGET), reduction in ulcer complications: randomised controlled trial. Lancet 2004; 364: 665-74.
    • (2004) Lancet , vol.364 , pp. 665-674
    • Schnitzer, T.J.1    Burmester, G.R.2    Mysler, E.3
  • 70
    • 78649466033 scopus 로고    scopus 로고
    • [accessed 18 June 2010].
    • [accessed 18 June 2010].
  • 71
    • 37349123992 scopus 로고    scopus 로고
    • Are COX-2 inhibitors preferable to non-selective non-steroidal anti-inflammatory drugs in patients with risk of cardiovascular events taking low-dose aspirin?
    • Strand V. Are COX-2 inhibitors preferable to non-selective non-steroidal anti-inflammatory drugs in patients with risk of cardiovascular events taking low-dose aspirin? Lancet 2007; 370: 2138-51.
    • (2007) Lancet , vol.370 , pp. 2138-2151
    • Strand, V.1
  • 72
    • 77955049924 scopus 로고    scopus 로고
    • Celecoxib versus omeprazole and diclofenac in patients with osteoarthritis and rheumatoid arthritis (CONDOR): a randomised trial
    • Chan FKL, Lanas A, Scheiman J, Berger MF, Nguyen H, Goldstein JL. Celecoxib versus omeprazole and diclofenac in patients with osteoarthritis and rheumatoid arthritis (CONDOR): a randomised trial. Lancet 2010; 376: 173-9.
    • (2010) Lancet , vol.376 , pp. 173-179
    • Chan, F.K.L.1    Lanas, A.2    Scheiman, J.3    Berger, M.F.4    Nguyen, H.5    Goldstein, J.L.6
  • 73
    • 34247464709 scopus 로고    scopus 로고
    • Use of nonsteroidal antiinflammatory drugs: an update for clinicians: a scientific statement from the American Heart Association
    • Antman EM, Bennett JS, Daugherty A et al. Use of nonsteroidal antiinflammatory drugs: an update for clinicians: a scientific statement from the American Heart Association. Circulation 2007; 115: 1634-42.
    • (2007) Circulation , vol.115 , pp. 1634-1642
    • Antman, E.M.1    Bennett, J.S.2    Daugherty, A.3
  • 74
    • 12144290072 scopus 로고    scopus 로고
    • Clinical pharmacology of platelet, monocyte, and vascular cyclooxygenase inhibition by naproxen and low-dose aspirin in healthy subjects
    • Capone ML, Tacconelli S, Sciulli MG et al. Clinical pharmacology of platelet, monocyte, and vascular cyclooxygenase inhibition by naproxen and low-dose aspirin in healthy subjects. Circulation 2004; 109: 1468-71.
    • (2004) Circulation , vol.109 , pp. 1468-1471
    • Capone, M.L.1    Tacconelli, S.2    Sciulli, M.G.3
  • 75
    • 77953806506 scopus 로고    scopus 로고
    • Bleeding complications with dual antiplatelet therapy among patients with stable vascular disease or risk factors for vascular disease: results from the Clopidogrel for High Atherothrombotic Risk and Ischemic Stabilization, Management, and Avoidance (CHARISMA) trial
    • Berger PB, Bhatt DL, Fuster V et al. Bleeding complications with dual antiplatelet therapy among patients with stable vascular disease or risk factors for vascular disease: results from the Clopidogrel for High Atherothrombotic Risk and Ischemic Stabilization, Management, and Avoidance (CHARISMA) trial. Circulation 2010; 121: 2575-83.
    • (2010) Circulation , vol.121 , pp. 2575-2583
    • Berger, P.B.1    Bhatt, D.L.2    Fuster, V.3
  • 76
    • 58749093909 scopus 로고    scopus 로고
    • Bleeding risk associated with 1 year of dual antiplatelet therapy after percutaneous coronary intervention: insights from the Clopidogrel for the Reduction of Events During Observation (CREDO) trial
    • CREDO Investigators.
    • Aronow HD, Steinhubl SR, Brennan DM, Berger PB, Topol EJ; CREDO Investigators. Bleeding risk associated with 1 year of dual antiplatelet therapy after percutaneous coronary intervention: insights from the Clopidogrel for the Reduction of Events During Observation (CREDO) trial. Am Heart J 2009; 157: 369-74.
    • (2009) Am Heart J , vol.157 , pp. 369-374
    • Aronow, H.D.1    Steinhubl, S.R.2    Brennan, D.M.3    Berger, P.B.4    Topol, E.J.5
  • 77
    • 71749087343 scopus 로고    scopus 로고
    • Risk of bleeding in patients with acute myocardial infarction treated with different combinations of aspirin, clopidogrel, and vitamin K antagonists in Denmark: a retrospective analysis of nationwide registry data
    • Sørensen R, Hansen ML, Abildstrom SZ et al. Risk of bleeding in patients with acute myocardial infarction treated with different combinations of aspirin, clopidogrel, and vitamin K antagonists in Denmark: a retrospective analysis of nationwide registry data. Lancet 2009; 374: 1967-74.
    • (2009) Lancet , vol.374 , pp. 1967-1974
    • Sørensen, R.1    Hansen, M.L.2    Abildstrom, S.Z.3
  • 78
    • 74849120868 scopus 로고    scopus 로고
    • Continuation of low-dose aspirin therapy in peptic ulcer bleeding: a randomized trial
    • Sung JJ, Lau JY, Ching JY et al. Continuation of low-dose aspirin therapy in peptic ulcer bleeding: a randomized trial. Ann Intern Med 2010; 152: 1-9.
    • (2010) Ann Intern Med , vol.152 , pp. 1-9
    • Sung, J.J.1    Lau, J.Y.2    Ching, J.Y.3
  • 79
    • 56749183852 scopus 로고    scopus 로고
    • ACCF/ACG/AHA 2008 expert consensus document on reducing the gastrointestinal risks of antiplatelet therapy and NSAID use: a report of the American College of Cardiology Foundation Task Force on Clinical Expert Consensus Documents
    • Bhatt DL, Scheiman J, Abraham NS et al. ACCF/ACG/AHA 2008 expert consensus document on reducing the gastrointestinal risks of antiplatelet therapy and NSAID use: a report of the American College of Cardiology Foundation Task Force on Clinical Expert Consensus Documents. Circulation 2008; 118: 1894-909.
    • (2008) Circulation , vol.118 , pp. 1894-1909
    • Bhatt, D.L.1    Scheiman, J.2    Abraham, N.S.3
  • 80
    • 67649861111 scopus 로고    scopus 로고
    • Famotidine for the prevention of peptic ulcers and oesophagitis in patients taking low-dose aspirin (FAMOUS): a phase III, randomised, double-blind, placebo-controlled trial
    • Taha AS, McCloskey C, Prasad R, Bezlyak V. Famotidine for the prevention of peptic ulcers and oesophagitis in patients taking low-dose aspirin (FAMOUS): a phase III, randomised, double-blind, placebo-controlled trial. Lancet 2009; 9684: 119-25.
    • (2009) Lancet , vol.9684 , pp. 119-125
    • Taha, A.S.1    McCloskey, C.2    Prasad, R.3    Bezlyak, V.4
  • 81
    • 0035967198 scopus 로고    scopus 로고
    • Preventing recurrent upper gastrointestinal bleeding in patients with Helicobacter pylori infection who are taking low-dose aspirin or naproxen
    • Chan FK, Chung SC, Suen BY et al. Preventing recurrent upper gastrointestinal bleeding in patients with Helicobacter pylori infection who are taking low-dose aspirin or naproxen. N Engl J Med 2001; 344: 967-73.
    • (2001) N Engl J Med , vol.344 , pp. 967-973
    • Chan, F.K.1    Chung, S.C.2    Suen, B.Y.3
  • 82
    • 0037182764 scopus 로고    scopus 로고
    • Lansoprazole for the prevention of recurrences of ulcer complications from long-term low-dose aspirin use
    • Lai KC, Lam SK, Chu KM et al. Lansoprazole for the prevention of recurrences of ulcer complications from long-term low-dose aspirin use. N Engl J Med 2002; 346: 2033-8.
    • (2002) N Engl J Med , vol.346 , pp. 2033-2038
    • Lai, K.C.1    Lam, S.K.2    Chu, K.M.3
  • 83
    • 78649468209 scopus 로고    scopus 로고
    • [accessed 26 October 2010].
    • & [accessed 26 October 2010].
  • 85
    • 73149119363 scopus 로고    scopus 로고
    • Identification of the human cytochrome P450 enzymes involved in the two oxidative steps in the bioactivation of clopidogrel to its pharmacologically active metabolite
    • Kazui M, Nishiya Y, Ishizuka T et al. Identification of the human cytochrome P450 enzymes involved in the two oxidative steps in the bioactivation of clopidogrel to its pharmacologically active metabolite. Drug Metab Dispos 2010; 38: 92-9.
    • (2010) Drug Metab Dispos , vol.38 , pp. 92-99
    • Kazui, M.1    Nishiya, Y.2    Ishizuka, T.3
  • 86
    • 33744968214 scopus 로고    scopus 로고
    • Increased risk of atherothrombotic events associated with cytochrome P450 3A5 polymorphism in patients taking clopidogrel
    • Suh JW, Koo BK, Zhang SY et al. Increased risk of atherothrombotic events associated with cytochrome P450 3A5 polymorphism in patients taking clopidogrel. CMAJ 2006; 174: 1715-22.
    • (2006) CMAJ , vol.174 , pp. 1715-1722
    • Suh, J.W.1    Koo, B.K.2    Zhang, S.Y.3
  • 87
    • 57149084688 scopus 로고    scopus 로고
    • Effect of atorvastatin on the pharmacokinetics and pharmacodynamics of prasugrel and clopidogrel in healthy subjects
    • Farid NA, Small DS, Payne CD et al. Effect of atorvastatin on the pharmacokinetics and pharmacodynamics of prasugrel and clopidogrel in healthy subjects. Pharmacotherapy 2008; 28: 1483-94.
    • (2008) Pharmacotherapy , vol.28 , pp. 1483-1494
    • Farid, N.A.1    Small, D.S.2    Payne, C.D.3
  • 88
    • 0036394942 scopus 로고    scopus 로고
    • Clinical significance of the cytochrome P450 2C19 genetic polymorphism
    • Desta Z, Zhao X, Shin JG, Flockhart DA. Clinical significance of the cytochrome P450 2C19 genetic polymorphism. Clin Pharmacokinet 2002; 41: 913-58.
    • (2002) Clin Pharmacokinet , vol.41 , pp. 913-958
    • Desta, Z.1    Zhao, X.2    Shin, J.G.3    Flockhart, D.A.4
  • 89
    • 65249145201 scopus 로고    scopus 로고
    • Cytochrome P450 2C19 loss-of-function polymorphism and stent thrombosis following percutaneous coronary intervention
    • Sibbing D, Stegherr J, Latz W et al. Cytochrome P450 2C19 loss-of-function polymorphism and stent thrombosis following percutaneous coronary intervention. Eur Heart J 2009; 30: 916-22.
    • (2009) Eur Heart J , vol.30 , pp. 916-922
    • Sibbing, D.1    Stegherr, J.2    Latz, W.3
  • 90
    • 58249135635 scopus 로고    scopus 로고
    • Cytochrome P450 2C19 polymorphism in young patients treated with clopidogrel after myocardial infarction: a cohort study
    • Collet JP, Hulot JS, Pena A et al. Cytochrome P450 2C19 polymorphism in young patients treated with clopidogrel after myocardial infarction: a cohort study. Lancet 2009; 373: 309-17.
    • (2009) Lancet , vol.373 , pp. 309-317
    • Collet, J.P.1    Hulot, J.S.2    Pena, A.3
  • 91
    • 69249219296 scopus 로고    scopus 로고
    • Association of cytochrome P450 2C19 genotype with the antiplatelet effect and clinical efficacy of clopidogrel therapy
    • Shuldiner AR, O'Connell JR, Bliden KP et al. Association of cytochrome P450 2C19 genotype with the antiplatelet effect and clinical efficacy of clopidogrel therapy. JAMA 2009; 302: 849-57.
    • (2009) JAMA , vol.302 , pp. 849-857
    • Shuldiner, A.R.1    O'Connell, J.R.2    Bliden, K.P.3
  • 92
    • 58749090547 scopus 로고    scopus 로고
    • Genetic determinants of response to clopidogrel and cardiovascular events
    • Simon T, Verstuyft C, Mary-Krause M et al. Genetic determinants of response to clopidogrel and cardiovascular events. N Engl J Med 2009; 360: 363-75.
    • (2009) N Engl J Med , vol.360 , pp. 363-375
    • Simon, T.1    Verstuyft, C.2    Mary-Krause, M.3
  • 93
    • 58749094444 scopus 로고    scopus 로고
    • Cytochrome p-450 polymorphisms and response to clopidogrel
    • Mega JL, Close SL, Wiviott SD et al. Cytochrome p-450 polymorphisms and response to clopidogrel. N Engl J Med 2009; 360: 354-62.
    • (2009) N Engl J Med , vol.360 , pp. 354-362
    • Mega, J.L.1    Close, S.L.2    Wiviott, S.D.3
  • 94
    • 76349098199 scopus 로고    scopus 로고
    • Cytochrome 2C19*17 allelic variant, platelet aggregation, bleeding events, and stent thrombosis in clopidogrel-treated patients with coronary stent placement
    • Sibbing D, Koch W, Gebhard D et al. Cytochrome 2C19*17 allelic variant, platelet aggregation, bleeding events, and stent thrombosis in clopidogrel-treated patients with coronary stent placement. Circulation 2010; 121: 512-8.
    • (2010) Circulation , vol.121 , pp. 512-518
    • Sibbing, D.1    Koch, W.2    Gebhard, D.3
  • 95
    • 33750079553 scopus 로고    scopus 로고
    • Influence of omeprazole on the antiplatelet action of clopidogrel associated to aspirin
    • Gilard M, Arnaud B, Le Gal G, Abgrall JF, Boschat J. Influence of omeprazole on the antiplatelet action of clopidogrel associated to aspirin. J Thromb Haemost 2006; 4: 2508-9.
    • (2006) J Thromb Haemost , vol.4 , pp. 2508-2509
    • Gilard, M.1    Arnaud, B.2    Le Gal, G.3    Abgrall, J.F.4    Boschat, J.5
  • 96
    • 38349065084 scopus 로고    scopus 로고
    • Influence of omeprazole on the antiplatelet action of clopidogrel associated with aspirin: the randomized, double-blind OCLA (Omeprazole Clopidogrel Aspirin) study
    • Gilard M, Arnaud B, Cornily JC et al. Influence of omeprazole on the antiplatelet action of clopidogrel associated with aspirin: the randomized, double-blind OCLA (Omeprazole Clopidogrel Aspirin) study. J Am Coll Cardiol 2008; 51: 256-60.
    • (2008) J Am Coll Cardiol , vol.51 , pp. 256-260
    • Gilard, M.1    Arnaud, B.2    Cornily, J.C.3
  • 97
    • 64849087438 scopus 로고    scopus 로고
    • Impact of proton pump inhibitors on the antiplatelet effects of clopidogrel
    • Sibbing D, Morath T, Stegherr J et al. Impact of proton pump inhibitors on the antiplatelet effects of clopidogrel. Thromb Haemost 2009; 101: 714-9.
    • (2009) Thromb Haemost , vol.101 , pp. 714-719
    • Sibbing, D.1    Morath, T.2    Stegherr, J.3
  • 98
    • 70049098599 scopus 로고    scopus 로고
    • Comparison of omeprazole and pantoprazole influence on a high 150-mg clopidogrel maintenance dose the PACA (Proton Pump Inhibitors And Clopidogrel Association) prospective randomized study
    • Cuisset T, Frere C, Quilici J et al. Comparison of omeprazole and pantoprazole influence on a high 150-mg clopidogrel maintenance dose the PACA (Proton Pump Inhibitors And Clopidogrel Association) prospective randomized study. J Am Coll Cardiol 2009; 54: 1149-53.
    • (2009) J Am Coll Cardiol , vol.54 , pp. 1149-1153
    • Cuisset, T.1    Frere, C.2    Quilici, J.3
  • 99
    • 77951687662 scopus 로고    scopus 로고
    • Risk of rehospitalization for patients using clopidogrel with a proton pump inhibitor
    • Stockl KM, Le L, Zakharyan A et al. Risk of rehospitalization for patients using clopidogrel with a proton pump inhibitor. Arch Intern Med 2010; 170: 704-10.
    • (2010) Arch Intern Med , vol.170 , pp. 704-710
    • Stockl, K.M.1    Le, L.2    Zakharyan, A.3
  • 100
    • 61549124132 scopus 로고    scopus 로고
    • Risk of adverse outcomes associated with concomitant use of clopidogrel and proton pump inhibitors following acute coronary syndrome
    • Ho PM, Maddox TM, Wang L et al. Risk of adverse outcomes associated with concomitant use of clopidogrel and proton pump inhibitors following acute coronary syndrome. JAMA 2009; 301: 937-44.
    • (2009) JAMA , vol.301 , pp. 937-944
    • Ho, P.M.1    Maddox, T.M.2    Wang, L.3
  • 101
    • 62649164844 scopus 로고    scopus 로고
    • A population-based study of the drug interaction between proton pump inhibitors and clopidogrel
    • Juurlink DN, Gomes T, Ko DT et al. A population-based study of the drug interaction between proton pump inhibitors and clopidogrel. CMAJ 2009; 180: 713-8.
    • (2009) CMAJ , vol.180 , pp. 713-718
    • Juurlink, D.N.1    Gomes, T.2    Ko, D.T.3
  • 102
    • 77954396061 scopus 로고    scopus 로고
    • Risk of adverse clinical outcomes with concomitant use of clopidogrel and proton pump inhibitors following percutaneous coronary intervention
    • Gupta E, Bansal D, Sotos J, Olden K. Risk of adverse clinical outcomes with concomitant use of clopidogrel and proton pump inhibitors following percutaneous coronary intervention. Dig Dis Sci 2010; 55: 1964-8.
    • (2010) Dig Dis Sci , vol.55 , pp. 1964-1968
    • Gupta, E.1    Bansal, D.2    Sotos, J.3    Olden, K.4
  • 103
    • 77950895115 scopus 로고    scopus 로고
    • Outcomes with concurrent use of clopidogrel and proton-pump inhibitors: a cohort study
    • Ray WA, Murray KT, Griffin MR et al. Outcomes with concurrent use of clopidogrel and proton-pump inhibitors: a cohort study. Ann Intern Med 2010; 152: 337-45.
    • (2010) Ann Intern Med , vol.152 , pp. 337-345
    • Ray, W.A.1    Murray, K.T.2    Griffin, M.R.3
  • 104
    • 73449122247 scopus 로고    scopus 로고
    • Cardiovascular outcomes and mortality in patients using clopidogrel with proton pump inhibitors after percutaneous coronary intervention or acute coronary syndrome
    • Rassen JA, Choudhry NK, Avorn J, Schneeweiss S. Cardiovascular outcomes and mortality in patients using clopidogrel with proton pump inhibitors after percutaneous coronary intervention or acute coronary syndrome. Circulation 2009; 120: 2322-9.
    • (2009) Circulation , vol.120 , pp. 2322-2329
    • Rassen, J.A.1    Choudhry, N.K.2    Avorn, J.3    Schneeweiss, S.4
  • 105
    • 77949690349 scopus 로고    scopus 로고
    • Meta-analysis: the effects of proton pump inhibitors on cardiovascular events and mortality in patients receiving clopidogrel
    • Kwok CS, Loke YK. Meta-analysis: the effects of proton pump inhibitors on cardiovascular events and mortality in patients receiving clopidogrel. Aliment Pharmacol Ther 2010; 31: 810-23.
    • (2010) Aliment Pharmacol Ther , vol.31 , pp. 810-823
    • Kwok, C.S.1    Loke, Y.K.2
  • 106
    • 78149487926 scopus 로고    scopus 로고
    • Clopidogrel with or without omeprazole in coronary artery disease
    • [Epub ahead of print].
    • Bhatt DL, Cryer BL, Contant CF et al. Clopidogrel with or without omeprazole in coronary artery disease. N Engl J Med 2010 [Epub ahead of print].
    • (2010) N Engl J Med
    • Bhatt, D.L.1    Cryer, B.L.2    Contant, C.F.3
  • 107
    • 77957372907 scopus 로고    scopus 로고
    • Proton-pump inhibitors are associated with increased cardiovascular risk independent of clopidogrel use
    • Charlot M, Ahlehoff O, Norgaard ML et al. Proton-pump inhibitors are associated with increased cardiovascular risk independent of clopidogrel use. Ann Intern Med 2010; 153: 378-86.
    • (2010) Ann Intern Med , vol.153 , pp. 378-386
    • Charlot, M.1    Ahlehoff, O.2    Norgaard, M.L.3
  • 108
    • 77955425743 scopus 로고    scopus 로고
    • ACCF/AHA Clopidogrel Clinical Alert: Approaches to the FDA "Boxed Warning". A Report of the American College of Cardiology Foundation Task Force on Clinical Expert Consensus Documents and the American Heart Association
    • Holmes Jr DR, Dehmer GJ, Kaul S, Leifer D, O'Gara PT, Stein CM. ACCF/AHA Clopidogrel Clinical Alert: Approaches to the FDA "Boxed Warning". A Report of the American College of Cardiology Foundation Task Force on Clinical Expert Consensus Documents and the American Heart Association. Circulation 2010; 122: 537-57.
    • (2010) Circulation , vol.122 , pp. 537-557
    • Holmes Jr, D.R.1    Dehmer, G.J.2    Kaul, S.3    Leifer, D.4    O'Gara, P.T.5    Stein, C.M.6
  • 109
    • 78649452627 scopus 로고    scopus 로고
    • FDA Letter of Approval: November 12, 2009, NDA 20-839/S-044. U.S. Food and Drug Administration. Available at: [accessed 2 July 2010].
    • Southworth MR. FDA Letter of Approval: November 12, 2009, NDA 20-839/S-044. U.S. Food and Drug Administration. Available at: [accessed 2 July 2010].
    • Southworth, M.R.1
  • 110
    • 0037422534 scopus 로고    scopus 로고
    • Atorvastatin reduces the ability of clopidogrel to inhibit platelet aggregation: a new drug-drug interaction
    • Lau WC, Waskell LA, Watkins PB et al. Atorvastatin reduces the ability of clopidogrel to inhibit platelet aggregation: a new drug-drug interaction. Circulation 2003; 107: 32-7.
    • (2003) Circulation , vol.107 , pp. 32-37
    • Lau, W.C.1    Waskell, L.A.2    Watkins, P.B.3
  • 111
    • 6344226832 scopus 로고    scopus 로고
    • Absence of interaction between atorvastatin or other statins and clopidogrel: results from the interaction study
    • Serebruany VL, Midei MG, Malinin AI et al. Absence of interaction between atorvastatin or other statins and clopidogrel: results from the interaction study. Arch Intern Med 2004; 164: 2051-7.
    • (2004) Arch Intern Med , vol.164 , pp. 2051-2057
    • Serebruany, V.L.1    Midei, M.G.2    Malinin, A.I.3
  • 112
    • 38349168982 scopus 로고    scopus 로고
    • Impact of cytochrome P450 3A4-metabolized statins on the antiplatelet effect of a 600-mg loading dose clopidogrel and on clinical outcome in patients undergoing elective coronary stent placement
    • Trenk D, Hochholzer W, Frundi D et al. Impact of cytochrome P450 3A4-metabolized statins on the antiplatelet effect of a 600-mg loading dose clopidogrel and on clinical outcome in patients undergoing elective coronary stent placement. Thromb Haemost 2008; 99: 174-81.
    • (2008) Thromb Haemost , vol.99 , pp. 174-181
    • Trenk, D.1    Hochholzer, W.2    Frundi, D.3
  • 113
    • 70349887593 scopus 로고    scopus 로고
    • Influence of statin treatment on platelet inhibition by clopidogrel - a randomized comparison of rosuvastatin, atorvastatin and simvastatin co-treatment
    • CASTOR investigators.
    • Malmström RE, Ostergren J, Jørgensen L, Hjemdahl P; CASTOR investigators. Influence of statin treatment on platelet inhibition by clopidogrel - a randomized comparison of rosuvastatin, atorvastatin and simvastatin co-treatment. J Intern Med 2009; 266: 457-66.
    • (2009) J Intern Med , vol.266 , pp. 457-466
    • Malmström, R.E.1    Ostergren, J.2    Jørgensen, L.3    Hjemdahl, P.4
  • 114
    • 0034033399 scopus 로고    scopus 로고
    • Inhibition of human cytochrome P450 enzymes by 1,4-dihydropyridine calcium antagonists: prediction of in vivo drug-drug interactions
    • Katoh M, Nakajima M, Shimada N, Yamazaki H, Yokoi T. Inhibition of human cytochrome P450 enzymes by 1, 4-dihydropyridine calcium antagonists: prediction of in vivo drug-drug interactions. Eur J Clin Pharmacol 2000; 55: 843-52.
    • (2000) Eur J Clin Pharmacol , vol.55 , pp. 843-852
    • Katoh, M.1    Nakajima, M.2    Shimada, N.3    Yamazaki, H.4    Yokoi, T.5
  • 116
    • 77955385753 scopus 로고    scopus 로고
    • Formation and fate of a sulfenic acid intermediate in the metabolic activation of the antithrombotic prodrug prasugrel (dagger)
    • Dansette PM, Thébault S, Bertho G, Mansuy D. Formation and fate of a sulfenic acid intermediate in the metabolic activation of the antithrombotic prodrug prasugrel (dagger). Chem Res Toxicol 2010; 23: 1268-74.
    • (2010) Chem Res Toxicol , vol.23 , pp. 1268-1274
    • Dansette, P.M.1    Thébault, S.2    Bertho, G.3    Mansuy, D.4
  • 117
    • 75749102996 scopus 로고    scopus 로고
    • Metabolism and disposition of the thienopyridine antiplatelet drugs ticlopidine, clopidogrel, and prasugrel in humans
    • Farid NA, Kurihara A, Wrighton SA. Metabolism and disposition of the thienopyridine antiplatelet drugs ticlopidine, clopidogrel, and prasugrel in humans. J Clin Pharmacol 2010; 50: 126-42.
    • (2010) J Clin Pharmacol , vol.50 , pp. 126-142
    • Farid, N.A.1    Kurihara, A.2    Wrighton, S.A.3
  • 118
    • 77952305027 scopus 로고    scopus 로고
    • Biotransformation of prasugrel, a novel thienopyridine antiplatelet agent, to the pharmacologically active metabolite
    • Hagihara K, Kazui M, Kurihara A et al. Biotransformation of prasugrel, a novel thienopyridine antiplatelet agent, to the pharmacologically active metabolite. Drug Metab Dispos 2010; 38: 898-904.
    • (2010) Drug Metab Dispos , vol.38 , pp. 898-904
    • Hagihara, K.1    Kazui, M.2    Kurihara, A.3
  • 119
    • 33645105318 scopus 로고    scopus 로고
    • Interaction of two major metabolites of prasugrel; a thiopyridine antiplatelet agent, with the cytochromes P450
    • Rehmel JL, Eckstein JA, Farid NA, Helm JB, Kasper SC, Kurihara A. Interaction of two major metabolites of prasugrel; a thiopyridine antiplatelet agent, with the cytochromes P450. Drug Metab Dispos 2006; 34: 600-7.
    • (2006) Drug Metab Dispos , vol.34 , pp. 600-607
    • Rehmel, J.L.1    Eckstein, J.A.2    Farid, N.A.3    Helm, J.B.4    Kasper, S.C.5    Kurihara, A.6
  • 120
    • 70350332201 scopus 로고    scopus 로고
    • A possible mechanism for the differences in efficiency and variability of active metabolite formation from thienopyridine antiplatelet agents, prasugrel and clopidogrel
    • Hagihara K, Kazui M, Kurihara A et al. A possible mechanism for the differences in efficiency and variability of active metabolite formation from thienopyridine antiplatelet agents, prasugrel and clopidogrel. Drug Metab Dispos 2009; 37: 2145-52.
    • (2009) Drug Metab Dispos , vol.37 , pp. 2145-2152
    • Hagihara, K.1    Kazui, M.2    Kurihara, A.3
  • 121
    • 37349111065 scopus 로고    scopus 로고
    • Prasugrel compared with high loading and maintenance - dose clopidogrel in patients with planned percutaneous coronary intervention: the prasugrelin comparison to clopidogrel for inhibition of platelet activation and aggregation-thrombolysis in myocardial infarction 44 trial
    • Wiviott SD, Trenk D, Frelinger AL, O'Donoghue M, Nreumann FJ, Michelson AD. Prasugrel compared with high loading and maintenance - dose clopidogrel in patients with planned percutaneous coronary intervention: the prasugrelin comparison to clopidogrel for inhibition of platelet activation and aggregation-thrombolysis in myocardial infarction 44 trial. Circulation 2007; 116: 2923-32.
    • (2007) Circulation , vol.116 , pp. 2923-2932
    • Wiviott, S.D.1    Trenk, D.2    Frelinger, A.L.3    O'Donoghue, M.4    Nreumann, F.J.5    Michelson, A.D.6
  • 122
    • 66349133650 scopus 로고    scopus 로고
    • Cytochrome P450 genetic polymorphisms and the response to prasugrel: relationship to pharmacokinetic, pharmacodynamic, and clinical outcomes
    • Mega JL, Close SL, Wiviott SD et al. Cytochrome P450 genetic polymorphisms and the response to prasugrel: relationship to pharmacokinetic, pharmacodynamic, and clinical outcomes. Circulation 2009; 119: 2553-60.
    • (2009) Circulation , vol.119 , pp. 2553-2560
    • Mega, J.L.1    Close, S.L.2    Wiviott, S.D.3
  • 123
    • 67651173161 scopus 로고    scopus 로고
    • Pharmacodynamic assessment of platelet inhibition by prasugrel vs. clopidogrel in the TRITON-TIMI 38 trial
    • Michelson AD, Frelinger III AL, Braunwald E et al. Pharmacodynamic assessment of platelet inhibition by prasugrel vs. clopidogrel in the TRITON-TIMI 38 trial. Eur Heart J 2009; 30: 1753-63.
    • (2009) Eur Heart J , vol.30 , pp. 1753-1763
    • Michelson, A.D.1    Frelinger III, A.L.2    Braunwald, E.3
  • 124
    • 36148983750 scopus 로고    scopus 로고
    • Prasugrel versus clopidogrel in patients with acute coronary syndromes
    • Wiviott SD, Braunwald E, McCabe CH et al. Prasugrel versus clopidogrel in patients with acute coronary syndromes. N Engl J Med 2007; 357: 2001-15.
    • (2007) N Engl J Med , vol.357 , pp. 2001-2015
    • Wiviott, S.D.1    Braunwald, E.2    McCabe, C.H.3
  • 125
    • 60649112469 scopus 로고    scopus 로고
    • Prasugrel compared with clopidogrel in patients undergoing percutaneous coronary intervention for ST-elevation myocardial infarction (TRITON-TIMI 38): double-blind, randomised controlled trial
    • Montalescot G, Wiviott SD, Braunwald E et al. Prasugrel compared with clopidogrel in patients undergoing percutaneous coronary intervention for ST-elevation myocardial infarction (TRITON-TIMI 38): double-blind, randomised controlled trial. Lancet 2009; 373: 723-31.
    • (2009) Lancet , vol.373 , pp. 723-731
    • Montalescot, G.1    Wiviott, S.D.2    Braunwald, E.3
  • 126
    • 73949112820 scopus 로고    scopus 로고
    • Randomized double-blind assessment of the onset and offset of the antiplatelet effects of ticagrelor versus clopidogrel in patients with stable coronary artery disease: the ONSET/OFFSET study
    • Gurbel PA, Bliden KP, Butler K et al. Randomized double-blind assessment of the onset and offset of the antiplatelet effects of ticagrelor versus clopidogrel in patients with stable coronary artery disease: the ONSET/OFFSET study. Circulation 2009; 120: 2577-85.
    • (2009) Circulation , vol.120 , pp. 2577-2585
    • Gurbel, P.A.1    Bliden, K.P.2    Butler, K.3
  • 127
    • 77950508416 scopus 로고    scopus 로고
    • Response to ticagrelor in clopidogrel nonresponders and responders and the effect of switching therapies: the RESPOND study
    • Gurbel PA, Bliden KP, Butler K et al. Response to ticagrelor in clopidogrel nonresponders and responders and the effect of switching therapies: the RESPOND study. Circulation 2010; 121: 1188-99.
    • (2010) Circulation , vol.121 , pp. 1188-1199
    • Gurbel, P.A.1    Bliden, K.P.2    Butler, K.3
  • 128
    • 70649090353 scopus 로고    scopus 로고
    • Safety and feasibility of adjunctive antiplatelet therapy with intravenous elinogrel, a direct-acting and reversible P2Y12 ADP-receptor antagonist, before primary percutaneous intervention in patients with ST-elevation myocardial infarction.
    • the Early Rapid ReversAl of platelet thromboSis with intravenous Elinogrel before PCI to optimize reperfusion in acute Myocardial Infarction (ERASE MI) pilot trial.
    • Berger JS, Roe MT, Gibson CM et al. Safety and feasibility of adjunctive antiplatelet therapy with intravenous elinogrel, a direct-acting and reversible P2Y12 ADP-receptor antagonist, before primary percutaneous intervention in patients with ST-elevation myocardial infarction: the Early Rapid ReversAl of platelet thromboSis with intravenous Elinogrel before PCI to optimize reperfusion in acute Myocardial Infarction (ERASE MI) pilot trial. Am Heart J 2009; 158: 998-1004.
    • (2009) Am Heart J , vol.158 , pp. 998-1004
    • Berger, J.S.1    Roe, M.T.2    Gibson, C.M.3
  • 129
    • 13744265417 scopus 로고    scopus 로고
    • Use of selective serotonin reuptake inhibitors and risk of upper gastrointestinal tract bleeding: a population-based cohort study
    • Dalton SO, Johansen C, Mellemkjaer L, Nørgård B, Sørensen HT, Olsen JH. Use of selective serotonin reuptake inhibitors and risk of upper gastrointestinal tract bleeding: a population-based cohort study. Arch Intern Med 2003; 163: 59-64.
    • (2003) Arch Intern Med , vol.163 , pp. 59-64
    • Dalton, S.O.1    Johansen, C.2    Mellemkjaer, L.3    Nørgård, B.4    Sørensen, H.T.5    Olsen, J.H.6
  • 130
    • 33846983203 scopus 로고    scopus 로고
    • Clinical impact of selective serotonin reuptake inhibitors therapy with bleeding risks
    • Turner MS, May DB, Arthur RR, Xiong GL. Clinical impact of selective serotonin reuptake inhibitors therapy with bleeding risks. J Intern Med 2007; 261: 205-13.
    • (2007) J Intern Med , vol.261 , pp. 205-213
    • Turner, M.S.1    May, D.B.2    Arthur, R.R.3    Xiong, G.L.4
  • 131
    • 0041967519 scopus 로고    scopus 로고
    • Selective serotonin reuptake inhibitors yield additional antiplatelet protection in patients with congestive heart failure treated with antecedent aspirin
    • Serebruany VL, Glassman AH, Malinin AI et al. Selective serotonin reuptake inhibitors yield additional antiplatelet protection in patients with congestive heart failure treated with antecedent aspirin. Eur J Heart Fail 2003; 5: 517-21.
    • (2003) Eur J Heart Fail , vol.5 , pp. 517-521
    • Serebruany, V.L.1    Glassman, A.H.2    Malinin, A.I.3
  • 132
    • 0033598594 scopus 로고    scopus 로고
    • Association between selective serotonin reuptake inhibitors and upper gastrointestinal bleeding: population based case-control study
    • De Abajo FJ, Rodríguez LA, Montero D. Association between selective serotonin reuptake inhibitors and upper gastrointestinal bleeding: population based case-control study. BMJ 1999; 319: 1106-9.
    • (1999) BMJ , vol.319 , pp. 1106-1109
    • De Abajo, F.J.1    Rodríguez, L.A.2    Montero, D.3
  • 134
    • 33748099549 scopus 로고    scopus 로고
    • Interaction between selective serotonin reuptake inhibitors and nonsteroidal antiinflammatory drugs: review of the literature
    • Mort JR, Aparasu RR, Baer RK. Interaction between selective serotonin reuptake inhibitors and nonsteroidal antiinflammatory drugs: review of the literature. Pharmacotherapy 2006; 26: 1307-13.
    • (2006) Pharmacotherapy , vol.26 , pp. 1307-1313
    • Mort, J.R.1    Aparasu, R.R.2    Baer, R.K.3
  • 135
    • 44949109396 scopus 로고    scopus 로고
    • Gastro-intestinal haemorrhage risks of selective serotonin receptor antagonist therapy: a new look
    • Opatrny L, Delaney JA, Suissa S. Gastro-intestinal haemorrhage risks of selective serotonin receptor antagonist therapy: a new look. Br J Clin Pharmacol 2008; 66: 76-81.
    • (2008) Br J Clin Pharmacol , vol.66 , pp. 76-81
    • Opatrny, L.1    Delaney, J.A.2    Suissa, S.3
  • 136
    • 38549178876 scopus 로고    scopus 로고
    • Spanish-Italian Collaborative Group for the Epidemiology of Gastrointestinal Bleeding. Risk of upper gastrointestinal bleeding and the degree of serotonin reuptake inhibition by antidepressants: a case-control study
    • Vidal X, Ibáñez L, Vendrell L, Conforti A, Laporte JR. Spanish-Italian Collaborative Group for the Epidemiology of Gastrointestinal Bleeding. Risk of upper gastrointestinal bleeding and the degree of serotonin reuptake inhibition by antidepressants: a case-control study. Drug Saf 2008; 3: 159-68.
    • (2008) Drug Saf , vol.3 , pp. 159-168
    • Vidal, X.1    Ibáñez, L.2    Vendrell, L.3    Conforti, A.4    Laporte, J.R.5
  • 137
    • 33747617316 scopus 로고    scopus 로고
    • Spironolactone and risk of upper gastrointestinal events: population based case-control study
    • Verhamme K, Mosis G, Dieleman J, Stricker B, Sturkenboom M. Spironolactone and risk of upper gastrointestinal events: population based case-control study. BMJ 2006; 333: 330.
    • (2006) BMJ , vol.333 , pp. 330
    • Verhamme, K.1    Mosis, G.2    Dieleman, J.3    Stricker, B.4    Sturkenboom, M.5
  • 138
    • 0029873619 scopus 로고    scopus 로고
    • Risk of gastrointestinal haemorrhage with calcium antagonists in hypertensive persons over 67 years old
    • Pahor M, Guralnik JM, Furberg CD, Carbonin P, Havlik RJ. Risk of gastrointestinal haemorrhage with calcium antagonists in hypertensive persons over 67 years old. Lancet 1996; 347: 1061-5.
    • (1996) Lancet , vol.347 , pp. 1061-1065
    • Pahor, M.1    Guralnik, J.M.2    Furberg, C.D.3    Carbonin, P.4    Havlik, R.J.5
  • 139
    • 0034927862 scopus 로고    scopus 로고
    • Epidemiologic review of the calcium channel blocker drugs. An up-to-date perspective on the proposed hazards
    • Kizer JR, Kimmel SE. Epidemiologic review of the calcium channel blocker drugs. An up-to-date perspective on the proposed hazards. Arch Intern Med 2001; 161: 1145-58.
    • (2001) Arch Intern Med , vol.161 , pp. 1145-1158
    • Kizer, J.R.1    Kimmel, S.E.2
  • 140
    • 70249144272 scopus 로고    scopus 로고
    • Risk of combining PPIs with thienopyridines: fact or fiction?
    • Sibbing D, Kastrati A. Risk of combining PPIs with thienopyridines: fact or fiction? Lancet 2009; 374: 952-3.
    • (2009) Lancet , vol.374 , pp. 952-953
    • Sibbing, D.1    Kastrati, A.2
  • 141
    • 73149119363 scopus 로고    scopus 로고
    • Identification of the human cytochrome P450 enzymes involved in the two oxidative steps in the bioactivation of clopidogrel to its pharmacologically active metabolite
    • Kazui M, Nishiya Y, Ishizuka T et al. Identification of the human cytochrome P450 enzymes involved in the two oxidative steps in the bioactivation of clopidogrel to its pharmacologically active metabolite. Drug Metab Dispos 2010; 38: 92-9.
    • (2010) Drug Metab Dispos , vol.38 , pp. 92-99
    • Kazui, M.1    Nishiya, Y.2    Ishizuka, T.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.