Aspirin extrusion from human platelets through multidrug resistance protein-4-Mediated transport: Evidence of a reduced drug action in patients after coronary artery bypass grafting

Journal of the American College of Cardiology

Volumn 58, Issue 7, 2011, Pages 752-761

  Mattiello, Teresa ^a   Guerriero, Raffaella ^b   Lotti, Lavinia Vittoria ^a   Trifir, Elisabetta ^a   Felli, Maria Pia ^a   Barbarulo, Alessandro ^a   Pucci, Bruna ^a   Gazzaniga, Paola ^a   Gaudio, Carlo ^a   Frati, Luigi ^a   Pulcinelli, Fabio M ^a  

^a SAPIENZA UNIVERSITY OF ROME   (Italy)

^b ISTITUTO SUPERIORE DI SANITÀ   (Italy)

Author keywords

aspirin; bypass; MRP4; platelets

Indexed keywords

ACETYLSALICYLIC ACID; CYCLOOXYGENASE 1; DIPYRIDAMOLE; MULTIDRUG RESISTANCE PROTEIN 4; PROSTAGLANDIN SYNTHASE; SMALL INTERFERING RNA; THROMBOXANE B2; VERLUKAST;

ADULT; ARTICLE; CELL CULTURE; CELL LEVEL; CLINICAL ARTICLE; CONTROLLED STUDY; CORONARY ARTERY BYPASS GRAFT; DOT HYBRIDIZATION; DRUG INTERACTION; DRUG PROTEIN INTERACTION; DRUG SENSITIVITY; DRUG TRANSPORT; ELECTRON MICROSCOPY; ENZYME ACTIVITY; FEMALE; HEMATOPOIETIC STEM CELL; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE MICROSCOPY; IMMUNOGOLD ELECTRON MICROSCOPY; IN VITRO STUDY; INHIBITION KINETICS; MALE; MEGAKARYOCYTE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN TRANSPORT; RNA INTERFERENCE; THROMBOCYTE; THROMBOCYTE AGGREGATION INHIBITION; VOLUNTEER;

ADULT; ASPIRIN; BIOLOGICAL TRANSPORT; BLOOD PLATELETS; CELLS, CULTURED; CORONARY ARTERY BYPASS; CYCLIC AMP; CYCLOOXYGENASE 1; DINOPROSTONE; DRUG INTERACTIONS; DRUG RESISTANCE; FEMALE; FIBRINOLYTIC AGENTS; HUMANS; MALE; MIDDLE AGED; MULTIDRUG RESISTANCE-ASSOCIATED PROTEINS; PLATELET AGGREGATION; PLATELET AGGREGATION INHIBITORS; PROPIONATES; PROSTAGLANDIN-ENDOPEROXIDE SYNTHASES; QUINOLINES; RNA, SMALL INTERFERING; SALICYLIC ACID; THROMBOXANE B2;

EID: 79961185454     PISSN: 07351097     EISSN: 15583597     Source Type: Journal    
DOI: 10.1016/j.jacc.2011.03.049     Document Type: Article

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