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Volumn 3, Issue 12, 2012, Pages 1500-1504

Synthesis and biological evaluation of 4-chlorocolchicine derivatives as potent anticancer agents with broad effective dosage ranges

Author keywords

[No Author keywords available]

Indexed keywords

4 CHLOROCOLCHICINE DERIVATIVE; ANTINEOPLASTIC AGENT; BENZAMIDE; COLCHICINE DERIVATIVE; CYCLOHEXANECARBOXAMIDE; GLORIOSAMINE A; ISOVALERAMIDE; UNCLASSIFIED DRUG;

EID: 84870022543     PISSN: 20402503     EISSN: 20402511     Source Type: Journal    
DOI: 10.1039/c2md20250f     Document Type: Article
Times cited : (10)

References (26)
  • 21
    • 79956105142 scopus 로고    scopus 로고
    • Compound 26 that showed the most potent activity in vitro was unsuitable for evaluation in vivo because of its low solubility for use in intravenous injections The maximum dose (MD) was defined as the maximum single dose that induced less than 20% weight loss when the derivative was intravenously administered to a mouse on day 1 and 5
    • N. Yasobu M. Kitajima N. Kogure Y. Shishido T. Matsuzaki M. Nagaoka H. Takayama ACS Med. Chem. Lett. 2011 2 348 352
    • (2011) ACS Med. Chem. Lett. , vol.2 , pp. 348-352
    • Yasobu, N.1    Kitajima, M.2    Kogure, N.3    Shishido, Y.4    Matsuzaki, T.5    Nagaoka, M.6    Takayama, H.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.