Synthesis and biological evaluation of B-ring modified colchicine and isocolchicine analogs

Bioorganic and Medicinal Chemistry Letters

Volumn 16, Issue 10, 2006, Pages 2761-2764

  Cifuentes, Michael ^a   Schilling, Brett ^b   Ravindra, Rudravajhala ^b   Winter, Jacquelyn ^a   Janik, Mark E ^a  

^a STATE UNIVERSITY OF NEW YORK AT FREDONIA   (United States)

^b BINGHAMTON UNIVERSITY   (United States)

Author keywords

Antimitotic; Colchicine; Isocolchicine; SAR; Tubulin

Indexed keywords

ANTIMITOTIC AGENT; COLCHICINE; COLCHICINE DERIVATIVE; FUNCTIONAL GROUP; ISOCOLCHICINE DERIVATIVE; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL CULTURE; CHEMICAL MODIFICATION; CONTROLLED STUDY; CYTOTOXICITY; DRUG POTENCY; DRUG SCREENING; DRUG SYNTHESIS; HUMAN; HUMAN CELL; IC 50; MALE; MICROTUBULE ASSEMBLY;

ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; COLCHICINE; HUMANS;

EID: 33645848477     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2006.02.010     Document Type: Article

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